M Wilke

Summary

Country: Germany

Publications

  1. ncbi request reprint LI-tool: a new toolbox to assess lateralization in functional MR-data
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    J Neurosci Methods 163:128-36. 2007
  2. doi request reprint Template-O-Matic: a toolbox for creating customized pediatric templates
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Neuroimage 41:903-13. 2008
  3. pmc An iterative jackknife approach for assessing reliability and power of FMRI group analyses
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Tubingen, Germany
    PLoS ONE 7:e35578. 2012
  4. doi request reprint An alternative approach towards assessing and accounting for individual motion in fMRI timeseries
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, and Department of Neuroradiology, University of Tubingen, Germany
    Neuroimage 59:2062-72. 2012
  5. pmc Global and local development of gray and white matter volume in normal children and adolescents
    Marko Wilke
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Exp Brain Res 178:296-307. 2007
  6. ncbi request reprint An fMRI task battery for assessing hemispheric language dominance in children
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, Germany
    Neuroimage 32:400-10. 2006
  7. ncbi request reprint Comprehensive language mapping in children, using functional magnetic resonance imaging: what's missing counts
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Neuroreport 16:915-9. 2005
  8. doi request reprint Somatosensory system in two types of motor reorganization in congenital hemiparesis: topography and function
    Marko Wilke
    Pediatric Neurology and Developmental Medicine, University Children s Hospital, University of Tubingen, Tubingen, Germany
    Hum Brain Mapp 30:776-88. 2009
  9. ncbi request reprint Voxel-based morphometry in adolescents with bipolar disorder: first results
    Marko Wilke
    Imaging Research Center and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Psychiatry Res 131:57-69. 2004
  10. doi request reprint Combined functional and causal connectivity analyses of language networks in children: a feasibility study
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, University Children s Hospital, Tubingen, Tubingen, Germany
    Brain Lang 108:22-9. 2009

Detail Information

Publications38

  1. ncbi request reprint LI-tool: a new toolbox to assess lateralization in functional MR-data
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    J Neurosci Methods 163:128-36. 2007
    ..To allow a more standardized, reproducible and accessible evaluation of laterality effects, current and new approaches have been implemented in a versatile toolbox running within the spm2 or spm5 software environment...
  2. doi request reprint Template-O-Matic: a toolbox for creating customized pediatric templates
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Neuroimage 41:903-13. 2008
    ..We compare the performance of this approach with the current method of template generation and discuss the implications of our approach...
  3. pmc An iterative jackknife approach for assessing reliability and power of FMRI group analyses
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Tubingen, Germany
    PLoS ONE 7:e35578. 2012
    ..The approach is tested using different scenarios from a recent fMRI study (children performing a "dual-use" fMRI task, n = 39), and the implications of this approach are discussed...
  4. doi request reprint An alternative approach towards assessing and accounting for individual motion in fMRI timeseries
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, and Department of Neuroradiology, University of Tubingen, Germany
    Neuroimage 59:2062-72. 2012
    ..A more individualized approach to explaining motion-related variance may therefore be beneficial, depending on the scenario...
  5. pmc Global and local development of gray and white matter volume in normal children and adolescents
    Marko Wilke
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Exp Brain Res 178:296-307. 2007
    ..The knowledge of such influence allows for the consideration of age- and gender-effects in future pediatric neuroimaging studies and advances our understanding of normal and abnormal brain development...
  6. ncbi request reprint An fMRI task battery for assessing hemispheric language dominance in children
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, Germany
    Neuroimage 32:400-10. 2006
    ..It may thus be a useful tool in assessing normal and pathological language organization...
  7. ncbi request reprint Comprehensive language mapping in children, using functional magnetic resonance imaging: what's missing counts
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Neuroreport 16:915-9. 2005
    ..They also allow robust mapping of receptive language areas...
  8. doi request reprint Somatosensory system in two types of motor reorganization in congenital hemiparesis: topography and function
    Marko Wilke
    Pediatric Neurology and Developmental Medicine, University Children s Hospital, University of Tubingen, Tubingen, Germany
    Hum Brain Mapp 30:776-88. 2009
    ..This preserved pattern of somatosensory organization argues in favor of a differential lesion effect on motor and somatosensory functions and demonstrates a limited compensatory potential for the latter...
  9. ncbi request reprint Voxel-based morphometry in adolescents with bipolar disorder: first results
    Marko Wilke
    Imaging Research Center and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Psychiatry Res 131:57-69. 2004
    ..VBM confirmed bilaterally larger basal ganglia. Localized gray matter deficits in bipolar subjects were found in the medial temporal lobe, orbito-frontal cortex, and the anterior cingulate, confirming and extending earlier studies...
  10. doi request reprint Combined functional and causal connectivity analyses of language networks in children: a feasibility study
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, University Children s Hospital, Tubingen, Tubingen, Germany
    Brain Lang 108:22-9. 2009
    ....
  11. pmc Functional magnetic resonance imaging in pediatrics
    M Wilke
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Neuropediatrics 34:225-33. 2003
    ..We conclude that fMRI can successfully be applied in children and holds great promise for both research and clinical purposes...
  12. doi request reprint Manual, semi-automated, and automated delineation of chronic brain lesions: a comparison of methods
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Neuroimage 56:2038-46. 2011
    ..The detection of indirect lesion effects may be another application of such approaches in the future...
  13. doi request reprint Clinical functional MRI of the language domain in children with epilepsy
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Hum Brain Mapp 32:1882-93. 2011
    ..We conclude that important confounds need to be considered and that the pattern of language reorganization may be distinct from the patterns seen in later-onset epilepsy...
  14. ncbi request reprint Normative pediatric brain data for spatial normalization and segmentation differs from standard adult data
    M Wilke
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Ohio, USA
    Magn Reson Med 50:749-57. 2003
    ..To assess the effects of using pediatric a priori brain information, the data obtained in this study is available to the scientific community from our website (www.irc.cchmc.org)...
  15. ncbi request reprint Bright spots: correlations of gray matter volume with IQ in a normal pediatric population
    Marko Wilke
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Neuroimage 20:202-15. 2003
    ..The implications of our findings for normal development, pathological processes, and our understanding of cognition are discussed and related to previous findings...
  16. doi request reprint Why one task is not enough: functional MRI for atypical language organization in two children
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Eur J Paediatr Neurol 14:474-8. 2010
    ..These cases underline the necessity to use more than one fMRI task for the determination of hemispheric dominance, whenever possible. This is particularly relevant in children as unusual patterns of reorganization may be more likely...
  17. pmc Variability of gray and white matter during normal development: a voxel-based MRI analysis
    Marko Wilke
    Pediatric Psychiatry Imaging Research Center ML 5031, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Neuroreport 14:1887-90. 2003
    ..Our results emphasize the necessity to take this variability into account when planning pediatric neuroimaging studies...
  18. ncbi request reprint A combined bootstrap/histogram analysis approach for computing a lateralization index from neuroimaging data
    Marko Wilke
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Hoppe Seyler Str 1, 72076 Tubingen, Germany
    Neuroimage 33:522-30. 2006
    ..We conclude that the proposed methods yield a robust and specific lateralization index, sensitively detect outliers and allow to assess the underlying data quality...
  19. ncbi request reprint Reorganization of the cerebro-cerebellar network of language production in patients with congenital left-hemispheric brain lesions
    K Lidzba
    Department of Developmental Neurology, University Children s Hospital, Hoppe Seyler Str 1, Tubingen 72076, Germany
    Brain Lang 106:204-10. 2008
    ..We suggest that the developing brain reacts to early focal lesions in the left hemisphere with a mirror-image organization of the entire cerebro-cerebellar network engaged in speech production...
  20. pmc BOLD fMRI signal increases with age in selected brain regions in children
    Mark B Schapiro
    Division of Neurology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center and Research Foundation, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Neuroreport 15:2575-8. 2004
    ..Thus, BOLD effect increases with age in children during sensorimotor and language tasks...
  21. doi request reprint Increases in language lateralization in normal children as observed using magnetoencephalography
    Volker Ressel
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Hoppe Seyler Str 1, Tubingen 72076, Germany
    Brain Lang 106:167-76. 2008
    ..As performance in the VI task showed no correlation with age, this increase seems to be unrelated to performance. These results confirm an increase in hemispheric specialization as a function of normal brain maturation...
  22. ncbi request reprint Language lateralization in magnetoencephalography: two tasks to investigate hemispheric dominance
    Volker Ressel
    Department of Pediatric Neurology and Developmental Medicine, Children s Hospital, University of Tubingen, Germany
    Neuroreport 17:1209-13. 2006
    ..Our new vowel identification task yields significant left-lateralization in posterior language regions, making this silent and child-friendly task a valuable alternative for non-invasive language assessment in difficult populations...
  23. ncbi request reprint Lesion-induced right-hemispheric language and organization of nonverbal functions
    Karen Lidzba
    Department of Pediatric Neurology and Developmental Medicine, University Children s Hospital, Tubingen, Germany
    Neuroreport 17:929-33. 2006
    ..Instead, verbal and nonverbal functions were mediated by a common right-hemispheric network. This argues in favour of the 'crowding hypothesis'...
  24. ncbi request reprint Visuospatial deficits in patients with early left-hemispheric lesions and functional reorganization of language: consequence of lesion or reorganization?
    Karen Lidzba
    Department of Pediatric Neurology and Developmental Medicine, University Children s Hospital, Hoppe Seyler Str 1, D 72076 Tubingen, Germany
    Neuropsychologia 44:1088-94. 2006
    ..The scope of this study was to examine the relations between visuospatial skills and hemispheric preference for language, and between visuospatial skills and cerebral lesion size...
  25. pmc Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI study
    Vincent J Schmithorst
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, OH 45229, USA
    Hum Brain Mapp 26:139-47. 2005
    ..The results are consistent with the hypothesis that regionally specific increased fiber organization is a mechanism responsible for the normal development of white matter tracts...
  26. pmc Language processing during natural sleep in a 6-year-old boy, as assessed with functional MR imaging
    Marko Wilke
    Imaging Research Center and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, OH 45229, USA
    AJNR Am J Neuroradiol 24:42-4. 2003
    ..Our findings suggest that language processing does occur during natural sleep, even in young children. This potentially allows for an assessment of language functions, even in sleeping children...
  27. ncbi request reprint Automated detection of gray matter malformations using optimized voxel-based morphometry: a systematic approach
    M Wilke
    Imaging Research Center, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neuroimage 20:330-43. 2003
    ..Our approach, involving systematic alterations of parameters and evaluation, may be useful for other studies...
  28. ncbi request reprint Differences in white matter architecture between musicians and non-musicians: a diffusion tensor imaging study
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, Suite R056A, Cincinnati, OH 45229, USA
    Neurosci Lett 321:57-60. 2002
    ..Further areas also showed significant differences. We hypothesize that these changes are due to the cognitive and motor effects, respectively, of musical training...
  29. ncbi request reprint Assessment of spatial normalization of whole-brain magnetic resonance images in children
    Marko Wilke
    Imaging Research Center, Children s Hospital Research Foundation at Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Hum Brain Mapp 17:48-60. 2002
    ..Also, to minimize the amount of deformation during non-linear spatial normalization, a pediatric template should be used. Further implications of our findings on developmental neuroimaging studies are discussed...
  30. doi request reprint Motor cortex plasticity in ischemic perinatal stroke: a transcranial magnetic stimulation and functional MRI study
    Michael Walther
    Department of Neuropediatrics and Muscle Disorders, University Children s Hospital, Freiburg, Germany
    Pediatr Neurol 41:171-8. 2009
    ....
  31. pmc Infant brain probability templates for MRI segmentation and normalization
    Mekibib Altaye
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Neuroimage 43:721-30. 2008
    ..These templates may be used as prior probability distributions for segmentation and normalization; a key to improving the accuracy of these procedures in special populations...
  32. pmc Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging study
    Vincent J Schmithorst
    Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave, Suite R050A, Cincinnati, OH 45229, USA
    Radiology 222:212-8. 2002
    ..To evaluate differences in white matter diffusion properties as a function of age in healthy children and adolescents...
  33. ncbi request reprint Prefrontal-thalamic-cerebellar gray matter networks and executive functioning in schizophrenia
    NICOLAS RUSCH
    IRCCS Fondazione Santa Lucia, Rome, Italy
    Schizophr Res 93:79-89. 2007
    ....
  34. ncbi request reprint Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study
    Caleb M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Bipolar Disord 6:197-203. 2004
    ..In this study we utilized diffusion tensor imaging (DTI) to examine prefrontal white matter in patients with bipolar disorder...
  35. ncbi request reprint Anatomical signatures of dyslexia in children: unique information from manual and voxel based morphometry brain measures
    Mark A Eckert
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305, USA
    Cortex 41:304-15. 2005
    ..We conclude that manual and automated methods provide valuable and complementary approaches to the search for functionally significant neurobiological characteristics of dyslexia...
  36. ncbi request reprint Voxel-based morphometry in the detection of dysplasia and neoplasia in childhood epilepsy: combined grey/white matter analysis augments detection
    Jason M Bruggemann
    Sydney Children s Hospital and University of New South Wales, Randwick, New South Wales, Australia
    Epilepsy Res 77:93-101. 2007
    ..The aim of this exploratory study was to evaluate combined analysis of grey and white matter using VBM for detecting focal lesions underlying childhood epilepsy, and to establish the optimal statistical parameters in this context...
  37. ncbi request reprint Brain representation of active and passive hand movements in children
    Andrea Guzzetta
    Department of Developmental Neuroscience, Stella Maris Scientific Institute, Pisa, Italy
    Pediatr Res 61:485-90. 2007
    ..Passive and active tasks confirmed to be tightly coupled, thus supporting the idea of the former as a helpful performance-independent paradigm in the study of brain reorganization and presurgical assessment...
  38. ncbi request reprint Comparison of standard and optimized voxel-based morphometry for analysis of brain changes associated with temporal lobe epilepsy
    Simon S Keller
    Magnetic Resonance and Image Analysis Research Centre MARIARC, University of Liverpool, Pembroke Place, PO Box 147, Liverpool L69 3BX, UK
    Neuroimage 23:860-8. 2004
    ..We suggest that in studies of neurological disorders, optimized VBM analyses of GMV may reveal subtle neuroanatomical changes that are not identified in analyses of GMC...