Alexander Weymann

Summary

Country: Germany

Publications

  1. ncbi request reprint Development and evaluation of a perfusion decellularization porcine heart model--generation of 3-dimensional myocardial neoscaffolds
    Alexander Weymann
    Department of Cardiac Surgery, University of Heidelberg, Im Neuenheimer Feld 326 OG 2, 69120 Heidelberg, Germany
    Circ J 75:852-60. 2011
  2. doi request reprint In vitro generation of atrioventricular heart valve neoscaffolds
    Alexander Weymann
    Heart and Marfan Center, Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, UK
    Artif Organs 38:E118-28. 2014
  3. ncbi request reprint Q50, an iron-chelating and zinc-complexing agent, improves cardiac function in rat models of ischemia/reperfusion-induced myocardial injury
    Sevil Korkmaz
    Laboratory of Cardiac Surgery, Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Circ J 77:1817-26. 2013
  4. ncbi request reprint Surgical management of subaortic stenosis
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 19:390-3. 2013
  5. doi request reprint Nitric oxide- and heme-independent activation of soluble guanylate cyclase attenuates peroxynitrite-induced endothelial dysfunction in rat aorta
    Sevil Korkmaz
    Department of Cardiac Surgery, Laboratory of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    J Cardiovasc Pharmacol Ther 18:70-7. 2013
  6. doi request reprint Continuous-flow left ventricular assist device therapy in patients with preoperative hepatic failure: are we pushing the limits too far?
    Alexander Weymann
    Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, UK Department of Cardiac Surgery, Heart Center, University of Heidelberg, Heidelberg, Germany
    Artif Organs 39:336-42. 2015
  7. pmc Total aortic arch replacement: superior ventriculo-arterial coupling with decellularized allografts compared with conventional prostheses
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 9:e103588. 2014
  8. ncbi request reprint Tricuspid valve endocarditis with septic pulmonary emboli in a drug addict
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 18:481-4. 2012
  9. pmc Bioartificial heart: a human-sized porcine model--the way ahead
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center University of Heidelberg, Heidelberg, Germany
    PLoS ONE 9:e111591. 2014
  10. pmc Gender-specific differences in outcome of ascending aortic aneurysm surgery
    Carsten J Beller
    Heart Centre Heidelberg, Clinic for Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 10:e0124461. 2015

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Development and evaluation of a perfusion decellularization porcine heart model--generation of 3-dimensional myocardial neoscaffolds
    Alexander Weymann
    Department of Cardiac Surgery, University of Heidelberg, Im Neuenheimer Feld 326 OG 2, 69120 Heidelberg, Germany
    Circ J 75:852-60. 2011
    ..The aim of this study was to evaluate the potential of a perfusion decellularization model for whole heart tissue engineering...
  2. doi request reprint In vitro generation of atrioventricular heart valve neoscaffolds
    Alexander Weymann
    Heart and Marfan Center, Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, UK
    Artif Organs 38:E118-28. 2014
    ..These results warrant further research toward the generation of atrioventricular heart valve neoscaffolds on the basis of decellularized xenogeneic tissue...
  3. ncbi request reprint Q50, an iron-chelating and zinc-complexing agent, improves cardiac function in rat models of ischemia/reperfusion-induced myocardial injury
    Sevil Korkmaz
    Laboratory of Cardiac Surgery, Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Circ J 77:1817-26. 2013
    ....
  4. ncbi request reprint Surgical management of subaortic stenosis
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 19:390-3. 2013
    ..A calcified subaortic membrane was identified. The membrane was removed and the aneurysm was treated with a Bentall procedure. The patient recovered smoothly from surgery and was doing well 6 months after discharge. ..
  5. doi request reprint Nitric oxide- and heme-independent activation of soluble guanylate cyclase attenuates peroxynitrite-induced endothelial dysfunction in rat aorta
    Sevil Korkmaz
    Department of Cardiac Surgery, Laboratory of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    J Cardiovasc Pharmacol Ther 18:70-7. 2013
    ....
  6. doi request reprint Continuous-flow left ventricular assist device therapy in patients with preoperative hepatic failure: are we pushing the limits too far?
    Alexander Weymann
    Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, UK Department of Cardiac Surgery, Heart Center, University of Heidelberg, Heidelberg, Germany
    Artif Organs 39:336-42. 2015
    ....
  7. pmc Total aortic arch replacement: superior ventriculo-arterial coupling with decellularized allografts compared with conventional prostheses
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 9:e103588. 2014
    ..This study investigated ventriculoarterial coupling and vascular impedance after replacement of the aortic arch with conventional prostheses vs. decellularized allografts...
  8. ncbi request reprint Tricuspid valve endocarditis with septic pulmonary emboli in a drug addict
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 18:481-4. 2012
    ..The infected tricuspid valve was replaced with a mechanical heart valve, and the patient recovered uneventfully from surgery...
  9. pmc Bioartificial heart: a human-sized porcine model--the way ahead
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center University of Heidelberg, Heidelberg, Germany
    PLoS ONE 9:e111591. 2014
    ..Native hearts decellularized with preserved architecture and vasculature may provide an acellular tissue platform for organ regeneration. We sought to develop a tissue-engineered whole-heart neoscaffold in human-sized porcine hearts...
  10. pmc Gender-specific differences in outcome of ascending aortic aneurysm surgery
    Carsten J Beller
    Heart Centre Heidelberg, Clinic for Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 10:e0124461. 2015
    ..Gender specific differences receive increasing attention and are known to affect the outcome of cardiovascular diseases. We investigated possible risk-factors for gender-specific differences in ascending aortic aneurysm surgery...
  11. pmc Acute ethanol exposure increases the susceptibility of the donor hearts to ischemia/reperfusion injury after transplantation in rats
    Shiliang Li
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 7:e49237. 2012
    ..The aims of this work were 1) to evaluate in rats the time-course cardiac effects of acute ethanol-exposure and 2) to explore how its abuse by donors might affect recipients in cardiac pump function after transplantation...
  12. ncbi request reprint Reendothelialization of human heart valve neoscaffolds using umbilical cord-derived endothelial cells
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center, University of Heidelberg, Heidelberg, Germany
    Circ J 77:207-16. 2013
    ..The aim of this study was to develop tissue engineered heart valves combining human umbilical vein endothelial cells (HUVECs) and decellularized human heart valve matrices...
  13. doi request reprint Constrictive pericarditis: risks, aetiologies and outcomes after total pericardiectomy: 24 years of experience
    Gabor Szabo
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Eur J Cardiothorac Surg 44:1023-8; discussion 1028. 2013
    ..This study was designed to compare the association of aetiology of constrictive pericarditis and other clinical variables, with long-term survival after total pericardiectomy...
  14. ncbi request reprint Entanglement of a circular mapping catheter in the mitral valve with persistent iatrogenic atrial septal defect after attempted pulmonary vein isolation: a word of caution
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 20:250-2. 2014
    ..Following multiple failed attempts to remove the catheter in the catheterization laboratory, the patient needed an emergency operation using the heart-lung machine...
  15. doi request reprint Massive calcified tricuspid valve endocarditis in a patient with dual lumen tunneled venous catheter
    Mina Farag
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 20:730-3. 2014
    ..The calcification aroused from the tip of the dual lumen tunneled venous catheter used for routine dialysis. We replaced the tricuspid valve with mechanical valve prosthesis and reconstructed the right atrium. ..
  16. doi request reprint Extracorporeal life support with an integrated left ventricular vent in children with a low cardiac output
    Stany Sandrio
    1Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Cardiol Young 24:654-60. 2014
    ..The aim of this study was to evaluate our experience in central extracorporeal life support with an integrated left ventricular vent in children with cardiac failure...
  17. ncbi request reprint Orthotopic heart transplantation in a patient with persistent left superior vena cava
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center, University of Heidelberg, Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 18:554-6. 2012
    ..We would like to discuss this rare case of an orthotopic heart transplantation in a recipient with an unknown history of persistent left superior vena cava...
  18. doi request reprint Treatment of ascending aortic aneurysms using different surgical techniques: a single-centre experience with 548 patients
    Klaus Kallenbach
    Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany
    Eur J Cardiothorac Surg 44:337-45. 2013
    ..Here, we describe the early and late outcomes after composite replacement (CR), supracommissural aortic replacement (SCR) and aortic valve-sparing (AVS) operations...
  19. doi request reprint Enhancement of myocardial and vascular function after phosphodiesterase-5 inhibition in a rat model
    Sivakkanan Loganathan
    Department of Cardiac Surgery, University of Heidelberg, Im Neuenheimer Feld 326, Heidelberg, Germany
    Thorac Cardiovasc Surg 60:247-54. 2012
    ..In the present study, we investigated the effects of vardenafil on myocardial contractility and vascular function in a dose-response study...
  20. ncbi request reprint Thromboembolus crossing patent foramen ovale: appearance in multislice computed tomography and echocardiography
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center, University of Heidelberg, INF 110, 69120 Heidelberg, Germany
    Ann Thorac Cardiovasc Surg 18:256-8. 2012
    ..Furthermore, a highly mobile mass trapped in her patent foramen ovale was identified. She underwent emergency cardiac embolectomy and was discharged from our hospital with conventional anticoagulant therapy...
  21. doi request reprint Resolution of heart block after surgical correction of failed transcatheter aortic valve implantation
    Alexander Weymann
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom Electronic address
    Ann Thorac Surg 99:1437-9. 2015
    ..Removal of a CoreValve prosthesis (Medtronic Inc, Minneapolis, MN) with standard aortic valve replacement resulted in restoration of sinus rhythm and valvular competencies. ..
  22. doi request reprint Gender differences in continuous-flow left ventricular assist device therapy as a bridge to transplantation: a risk-adjusted comparison using a propensity score-matching analysis
    Alexander Weymann
    Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, UK Department of Cardiac Surgery, Heart Center, University of Heidelberg, Heidelberg, Germany
    Artif Organs 39:212-9. 2015
    ..Further studies are required to identify additional demographic and clinical factors that modulate outcomes and will enhance the ability to risk-stratify cfLVAD recipients. ..
  23. doi request reprint The Ross procedure: suitable for everyone?
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center University of Heidelberg, INF 110, 69120 Heidelberg, Germany
    Expert Rev Cardiovasc Ther 12:549-56. 2014
    ..However, the Ross procedure is a complex operation; careful patient selection and experience of the surgeon are mandatory requirements to achieve satisfactory results. ..
  24. pmc Surgical treatment of infective endocarditis in active intravenous drug users: a justified procedure?
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center, University Hospital of Heidelberg, Im Neuenheimer Feld 110, Heidelberg 69120, Germany
    J Cardiothorac Surg 9:58. 2014
    ....
  25. doi request reprint Reproducibility in echocardiographic two- and three-dimensional mitral valve assessment
    Maximilian Dominik Hien
    Department of Anesthesiology, University of Heidelberg, Heidelberg, Germany Department of Pediatrics, University of Heidelberg, Heidelberg, Germany Research Training Group 1126, German Research Foundation DFG, Bonn, Germany
    Echocardiography 31:311-7. 2014
    ..This multicenter study aimed to determine reliability of 2D and 3DTEE mitral valve evaluations by calculating inter-observer agreement between various echocardiographers...
  26. doi request reprint Temporary tricuspid valve detachment for ventricular septal defect closure: is it worth doing it?
    Alexander Weymann
    Department of Cardiac Surgery, Heart Center University of Heidelberg, Heidelberg, Germany
    Heart Surg Forum 16:E99-102. 2013
    ..Tricuspid valve detachment (TVD) may improve the access for closing certain ventricular septal defects (VSDs), but it has some potential risks. We aimed to study the benefits and drawbacks of this technique...
  27. doi request reprint Experts and beginners benefit from three-dimensional echocardiography: a multicenter study on the assessment of mitral valve prolapse
    Maximilian Dominik Hien
    Research Training Group 1126, German Research Foundation, Heidelberg, Germany
    J Am Soc Echocardiogr 26:828-34. 2013
    ..This multicenter study was designed to assess the differences between experts and inexperienced echocardiographers in localizing MVP and ruptured chordae tendineae using 2D and real-time 3D TEE...
  28. pmc Eprosartan improves cardiac function in swine working heart model of ischemia-reperfusion injury
    Alexander Weymann
    Department of Cardiac Surgery, Heart and Marfan Center University of Heidelberg, Heidelberg, Germany
    Med Sci Monit Basic Res 20:55-62. 2014
    ..We sought to evaluate the regional effect of Eprosartan on postinfarct ventricular remodeling and myocardial function in an isolated swine working heart model of ischemia-reperfusion injury...
  29. doi request reprint Comparison of intraoperative three-dimensional Doppler color flow mapping to assess mitral regurgitation
    Maximilian D Hien
    Department of Pediatric Cardiology, University Medical Center, University of Heidelberg, Heidelberg, Germany
    Echocardiography 29:849-57. 2012
    ..The aim of this study was to determine the VCA in the operative setting and to compare it to alternative 3D and standard 2D methods, with respect to different etiologies of MR...