Katja C Weisel

Summary

Country: Germany

Publications

  1. doi request reprint Regulation of FLT3 and its ligand in normal hematopoietic progenitor cells
    Katja C Weisel
    Medical Center, Department of Hematology, Oncology and Immunology, University of Tubingen, Otfried Muller Strasse 10, 72076 Tubingen, Germany
    Ann Hematol 88:203-11. 2009
  2. doi request reprint Development of rapid light-chain deposition disease in hepatic arteries with severe ischemic cholangitis in a multiple myeloma patient treated with melphalan, prednisone and lenalidomide
    Katja C Weisel
    Medical Center, Department of Hematology, Oncology and Immunology, University of Tubingen, Otfried Muller Strasse 10, 72076, Tubingen, Germany
    Int J Hematol 89:91-4. 2009
  3. doi request reprint Epstein-Barr virus-associated B-cell lymphoma secondary to FCD-C therapy in patients with peripheral T-cell lymphoma
    Katja C Weisel
    Department of Hematology, Medizinische Klinik, Universitäaetsklinik Tübingen, Tubingen, Germany
    Int J Hematol 88:434-40. 2008
  4. doi request reprint Wnt1 overexpression leads to enforced cardiomyogenesis and inhibition of hematopoiesis in murine embryonic stem cells
    Katja C Weisel
    University of Tubingen, Medical Center, Department of Hematology, Oncology and Immunology, Tubingen, Germany
    Stem Cells Dev 19:745-51. 2010
  5. doi request reprint Extended in vitro expansion of adult, mobilized CD34+ cells without significant cell senescence using a stromal cell coculture system with single cytokine support
    Katja C Weisel
    Department of Hematology, Oncology, and Immunology, University of Tubingen, Medical Center, Tubingen, Germany
    Stem Cells Dev 18:229-34. 2009
  6. ncbi request reprint Effect of FLT3 inhibition on normal hematopoietic progenitor cells
    Katja C Weisel
    University of Tubingen, Medical Center, Department of Hematology, Oncology and Immunology, Otfried Muller Strasse 10, 72076 Tubingen, Germany
    Ann N Y Acad Sci 1106:190-6. 2007
  7. ncbi request reprint Stromal cell lines from the aorta-gonado-mesonephros region are potent supporters of murine and human hematopoiesis
    Katja C Weisel
    Laboratory of Developmental Hematopoiesis, Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Exp Hematol 34:1505-16. 2006
  8. ncbi request reprint Genetic and functional characterization of isolated stromal cell lines from the aorta-gonado-mesonephros region
    Katja C Weisel
    University of Tubingen, Department of Hematology, Oncology, and Immunology, Otfried Muller Strasse 10, 72076 Tubingen, Germany
    Ann N Y Acad Sci 1044:51-9. 2005
  9. ncbi request reprint Intravascular lymphoma - a rare cause of hemolytic anemia and neurologic disorders
    Katja C Weisel
    Department of Hematology, Oncology and Immunology, University of Tubingen, Medical Center, Otfried Muller Strasse 10, D 72076 Tubingen, Germany
    Hematol J 5:444-6. 2004
  10. ncbi request reprint Osteoprotegerin positively regulates hematopoietic progenitor cells
    Eric Schweikle
    University of Tubingen, Medical Center, Department of Hematology, Oncology and Immunology, Germany
    Curr Stem Cell Res Ther 7:72-7. 2012

Collaborators

Detail Information

Publications18

  1. doi request reprint Regulation of FLT3 and its ligand in normal hematopoietic progenitor cells
    Katja C Weisel
    Medical Center, Department of Hematology, Oncology and Immunology, University of Tubingen, Otfried Muller Strasse 10, 72076 Tubingen, Germany
    Ann Hematol 88:203-11. 2009
    ..In conclusion, FLT3 and its ligand regulate proliferation of hematopoietic progenitor cells in an autocrine/paracrine manner Nonspecific inhibition of FLT3 may contribute to hematotoxicity caused by imatinib treatment...
  2. doi request reprint Development of rapid light-chain deposition disease in hepatic arteries with severe ischemic cholangitis in a multiple myeloma patient treated with melphalan, prednisone and lenalidomide
    Katja C Weisel
    Medical Center, Department of Hematology, Oncology and Immunology, University of Tubingen, Otfried Muller Strasse 10, 72076, Tubingen, Germany
    Int J Hematol 89:91-4. 2009
    ..Histopathological analysis revealed LCDD of the hepatic arteries as the underlying cause. This is to our knowledge the first case of LCDD of terminal liver arteries as a cause of intrahepatic ischemic cholangitis...
  3. doi request reprint Epstein-Barr virus-associated B-cell lymphoma secondary to FCD-C therapy in patients with peripheral T-cell lymphoma
    Katja C Weisel
    Department of Hematology, Medizinische Klinik, Universitäaetsklinik Tübingen, Tubingen, Germany
    Int J Hematol 88:434-40. 2008
    ..We suggest to monitor the cellular immune status in combination with the EBV load in high risk patients for early detection-and possibly intervention-of EBV-associated lymphoma...
  4. doi request reprint Wnt1 overexpression leads to enforced cardiomyogenesis and inhibition of hematopoiesis in murine embryonic stem cells
    Katja C Weisel
    University of Tubingen, Medical Center, Department of Hematology, Oncology and Immunology, Tubingen, Germany
    Stem Cells Dev 19:745-51. 2010
    ..These findings suggest that Wnt1 may regulate differentiation of immature mesodermal cells in a tissue-specific manner...
  5. doi request reprint Extended in vitro expansion of adult, mobilized CD34+ cells without significant cell senescence using a stromal cell coculture system with single cytokine support
    Katja C Weisel
    Department of Hematology, Oncology, and Immunology, University of Tubingen, Medical Center, Tubingen, Germany
    Stem Cells Dev 18:229-34. 2009
    ..In conclusion, OP9/TPO system provides extensive stem cell expansion without concomitant telomere erosion for both CB and adult CD34(+) cells. Termination of adult CD34(+) cell cocultures seems to be independent of telomere length...
  6. ncbi request reprint Effect of FLT3 inhibition on normal hematopoietic progenitor cells
    Katja C Weisel
    University of Tubingen, Medical Center, Department of Hematology, Oncology and Immunology, Otfried Muller Strasse 10, 72076 Tubingen, Germany
    Ann N Y Acad Sci 1106:190-6. 2007
    ..Blocking the FLT3 ligand by a neutralizing antibody partially restored the effects of FLT3 inhibition. These findings might explain hematotoxicity of tyrosine kinase inhibitors such as imatinib...
  7. ncbi request reprint Stromal cell lines from the aorta-gonado-mesonephros region are potent supporters of murine and human hematopoiesis
    Katja C Weisel
    Laboratory of Developmental Hematopoiesis, Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Exp Hematol 34:1505-16. 2006
    ..In addition, extensive phenotypic analysis should elucidate possible mechanisms involved in maintenance of hematopoietic stem cell function...
  8. ncbi request reprint Genetic and functional characterization of isolated stromal cell lines from the aorta-gonado-mesonephros region
    Katja C Weisel
    University of Tubingen, Department of Hematology, Oncology, and Immunology, Otfried Muller Strasse 10, 72076 Tubingen, Germany
    Ann N Y Acad Sci 1044:51-9. 2005
    ..Stromal gene array analysis has identified genes that could play a role in hematopoietic support...
  9. ncbi request reprint Intravascular lymphoma - a rare cause of hemolytic anemia and neurologic disorders
    Katja C Weisel
    Department of Hematology, Oncology and Immunology, University of Tubingen, Medical Center, Otfried Muller Strasse 10, D 72076 Tubingen, Germany
    Hematol J 5:444-6. 2004
    ..We describe here a 76-year-old woman with the clinical diagnoses of hemolytic anemia and progressive lethargy where intravascular lymphomatosis turned out as the underlying cause of the disease...
  10. ncbi request reprint Osteoprotegerin positively regulates hematopoietic progenitor cells
    Eric Schweikle
    University of Tubingen, Medical Center, Department of Hematology, Oncology and Immunology, Germany
    Curr Stem Cell Res Ther 7:72-7. 2012
    ..The observed effects were partially antagonized by addition of RANKL. In conclusion, these findings suggest an important role of OPG maintaining progenitor cell function in the osteoblastic niche...
  11. ncbi request reprint Differential effects of G protein coupled receptors on hematopoietic progenitor cell growth depend on their signaling capacities
    Xingkui Xue
    Department of Medicine II, University of Tubingen, Otfried Muller Str 10, 72076 Tubingen, Germany
    Ann N Y Acad Sci 1106:180-9. 2007
    ....
  12. ncbi request reprint Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells VI, University of Tübingen, Germany, September 14-16, 2006
    Katja C Weisel
    Department of Hematology, Oncology and Immunology, University Medical Center II, Tubingen, Germany
    Exp Hematol 35:1005-14. 2007
  13. pmc Modulation of CXC chemokine receptor expression and function in human neutrophils during aging in vitro suggests a role in their clearance from circulation
    Katja C Weisel
    Department of Medicine II, University of Tubingen, Tubingen, Germany
    Mediators Inflamm 2009:790174. 2009
    ..Partially retained responsiveness to interleukin-8 may be important for neutrophil function when senescence occurs after extravasation in inflamed tissues...
  14. doi request reprint Successful treatment of patients with multiple myeloma and impaired renal function with lenalidomide: results of 4 German centers
    Katharina Oehrlein
    Division of Hematology, Oncology and Immunology, Medical Department, University Hospital of Tubingen, Tubingen, Germany
    Clin Lymphoma Myeloma Leuk 12:191-6. 2012
    ..Analysis showed myeloma overall response rate of 84%, with 42% of patients with improvement of renal function. Lenalidomide/dexamethasone is highly effective, with acceptable toxicity in the renally impaired patient group...
  15. doi request reprint Extracorporeal light chain elimination: high cut-off (HCO) hemodialysis parallel to chemotherapy allows for a high proportion of renal recovery in multiple myeloma patients with dialysis-dependent acute kidney injury
    Nils Heyne
    Department of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tubingen, Tubingen, Germany
    Ann Hematol 91:729-35. 2012
    ..Timely diagnosis and onset of therapy is essential for improving renal outcome...
  16. doi request reprint Proteasome inhibition by bortezomib: effect on HLA-antibody levels and specificity in sensitized patients awaiting renal allograft transplantation
    Martina Guthoff
    Department of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, Otfried Muller Str 10, 72076 Tubingen, Germany
    Transpl Immunol 26:171-5. 2012
    ..Here, we report the effect of bortezomib preconditioning on HLA antibody titers and specificity in highly sensitized patients awaiting renal allograft transplantation...
  17. ncbi request reprint Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells V, University of Tübingen, Germany, September 16-18, 2004
    Katja C Weisel
    Department of Hematology, Oncology and Immunology, University Medical Center II, Tubingen, Germany
    Exp Hematol 33:513-22. 2005
  18. ncbi request reprint Elevated telomerase activity and minimal telomere loss in cord blood long-term cultures with extensive stem cell replication
    Loretta Gammaitoni
    Department of Oncological Sciences, IRCC Institute for Cancer Research and Treatment, Laboratory of Clinical Oncology, University of Turin Medical School, Prov 142, 10060 Candiolo, Turin, Italy
    Blood 103:4440-8. 2004
    ..There is clearly a clinical value for a system that provides extensive stem cell expansion without concomitant telomere erosion...