Tim Wehner

Summary

Country: Germany

Publications

  1. doi request reprint Optimization of intramedullary nailing by numerical simulation of fracture healing
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, Ulm University, Helmholtzstrasse 14, 89081 Ulm, Germany
    J Orthop Res 30:569-73. 2012
  2. ncbi request reprint Internal loads in the human tibia during gait
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, University of Ulm, Germany
    Clin Biomech (Bristol, Avon) 24:299-302. 2009
  3. ncbi request reprint Influence of the fixation stability on the healing time--a numerical study of a patient-specific fracture healing process
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Ulm University, Helmholtzstrasse 14, Ulm, Germany
    Clin Biomech (Bristol, Avon) 25:606-12. 2010
  4. doi request reprint Internal forces and moments in the femur of the rat during gait
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Ulm University, Helmholtzstrasse 14, Ulm, Germany
    J Biomech 43:2473-9. 2010
  5. doi request reprint Improvement of the shear fixation stability of intramedullary nailing
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Ulm University, Germany
    Clin Biomech (Bristol, Avon) 26:147-51. 2011
  6. ncbi request reprint Disadvantages of interfragmentary shear on fracture healing--mechanical insights through numerical simulation
    Malte Steiner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University of Ulm, Ulm, Germany
    J Orthop Res 32:865-72. 2014
  7. doi request reprint Conversion from external fixator to intramedullary nail causes a second hit and impairs fracture healing in a severe trauma model
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, University of Ulm, Helmholtzstrasse 14, 89081 Ulm, Germany
    J Orthop Res 31:465-71. 2013
  8. pmc C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Helmholtzstr 14, 89081 Ulm, Germany
    J Orthop Res 30:581-6. 2012
  9. doi request reprint Systemic inflammation induced by a thoracic trauma alters the cellular composition of the early fracture callus
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, Center of Surgery, University of Ulm, Ulm, Germany
    J Trauma Acute Care Surg 74:531-7. 2013
  10. pmc The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing
    Aline Heilmann
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Ulm, Germany
    PLoS ONE 8:e84232. 2013

Collaborators

Detail Information

Publications19

  1. doi request reprint Optimization of intramedullary nailing by numerical simulation of fracture healing
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, Ulm University, Helmholtzstrasse 14, 89081 Ulm, Germany
    J Orthop Res 30:569-73. 2012
    ..To avoid a prolonged healing time, the nail should be thick, and the annular gap should be as narrow as possible. Alternatively, using steel instead of titanium may also help to avoid a prolonged healing time...
  2. ncbi request reprint Internal loads in the human tibia during gait
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, University of Ulm, Germany
    Clin Biomech (Bristol, Avon) 24:299-302. 2009
    ..Inverse dynamic musculoskeletal models were successfully used to determine the muscle forces in the lower extremities, however the internal loads expressed as forces and moments along the human tibia during gait have not been reported...
  3. ncbi request reprint Influence of the fixation stability on the healing time--a numerical study of a patient-specific fracture healing process
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Ulm University, Helmholtzstrasse 14, Ulm, Germany
    Clin Biomech (Bristol, Avon) 25:606-12. 2010
    ..The aim of this study was to simulate a patient-specific human healing process using a numerical algorithm and to retrospectively analyse the influence of the fixation stability on the healing time...
  4. doi request reprint Internal forces and moments in the femur of the rat during gait
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Ulm University, Helmholtzstrasse 14, Ulm, Germany
    J Biomech 43:2473-9. 2010
    ..Knowledge of the internal loads in the femur of the rat allows adjustment of the biomechanical properties of fixation devices in fracture healing studies to the desired interfragmentary movement...
  5. doi request reprint Improvement of the shear fixation stability of intramedullary nailing
    Tim Wehner
    Institute of Orthopaedic Research and Biomechanics, Ulm University, Germany
    Clin Biomech (Bristol, Avon) 26:147-51. 2011
    ..The aims of this study were to simulate the shear interfragmentary movement during gait for a human tibia treated with intramedullary nailing and to investigate if this movement could be lowered by implant design modifications...
  6. ncbi request reprint Disadvantages of interfragmentary shear on fracture healing--mechanical insights through numerical simulation
    Malte Steiner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University of Ulm, Ulm, Germany
    J Orthop Res 32:865-72. 2014
    ..Therefore, our findings suggest that osteosynthesis implants can be optimized, in particular, to limit translational interfragmentary shear under musculoskeletal loading...
  7. doi request reprint Conversion from external fixator to intramedullary nail causes a second hit and impairs fracture healing in a severe trauma model
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, University of Ulm, Helmholtzstrasse 14, 89081 Ulm, Germany
    J Orthop Res 31:465-71. 2013
    ..The results indicate that accumulation of second hits after multiple injuries could lead to aggravation of the fracture healing outcome...
  8. pmc C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Helmholtzstr 14, 89081 Ulm, Germany
    J Orthop Res 30:581-6. 2012
    ..C5a could possibly represent a target to prevent delayed bone healing in patients with severe trauma...
  9. doi request reprint Systemic inflammation induced by a thoracic trauma alters the cellular composition of the early fracture callus
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, Center of Surgery, University of Ulm, Ulm, Germany
    J Trauma Acute Care Surg 74:531-7. 2013
    ..The underlying cellular mechanisms, however, have as yet remained unknown. Therefore, the aim of this study was to analyze the cellular and morphologic composition of the early fracture callus after a blunt chest trauma...
  10. pmc The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing
    Aline Heilmann
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Ulm, Germany
    PLoS ONE 8:e84232. 2013
    ..The finding that Fzd9, in addition to its role in physiological bone remodeling, regulates bone repair may have implications for the development of treatments for poorly or non-healing fractures...
  11. pmc Prediction of fracture healing under axial loading, shear loading and bending is possible using distortional and dilatational strains as determining mechanical stimuli
    Malte Steiner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University of Ulm, Ulm, Germany
    J R Soc Interface 10:20130389. 2013
    ....
  12. doi request reprint Metaphyseal fracture healing follows similar biomechanical rules as diaphyseal healing
    Lutz Claes
    Center of Musculoskeletal Research, Institute of Orthopaedic Research and Biomechanics, University of Ulm, Ulm, Germany
    J Orthop Res 29:425-32. 2011
    ..It is therefore proposed that metaphyseal bone healing follows similar biomechanical principles as diaphyseal healing...
  13. ncbi request reprint Distinct frequency dependent effects of whole-body vibration on non-fractured bone and fracture healing in mice
    Esther Wehrle
    Institute of Orthopaedic Research and Biomechanics, Centre of Musculoskeletal Research, University of Ulm, Helmholtzstr 14, 89081 Ulm, Germany
    J Orthop Res 32:1006-13. 2014
    ..2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:1006-1013, 2014. ..
  14. doi request reprint Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice
    Aline Heilmann
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Ulm, Germany
    J Orthop Res 31:1845-50. 2013
    ..2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31:1845-1850, 2013. ..
  15. doi request reprint A computational method for determining tissue material properties in ovine fracture calluses using electronic speckle pattern interferometry and finite element analysis
    Malte Steiner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University of Ulm, Germany
    Med Eng Phys 34:1521-5. 2012
    ..In conclusion, a numerical method was developed to determine material properties straight from independent fracture callus specimens based on experimentally derived local mechanical conditions...
  16. doi request reprint Experimental blunt chest trauma impairs fracture healing in rats
    Stefan Recknagel
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Ulm, Germany
    J Orthop Res 29:734-9. 2011
    ..In confirming the clinical evidence, this study reports for the first time that a blunt chest trauma considerably impaired bone healing, possibly via the interaction of the induced systemic inflammation with local inflammatory processes...
  17. ncbi request reprint Numerical simulation of callus healing for optimization of fracture fixation stiffness
    Malte Steiner
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University Hospital Ulm, Ulm, Germany
    PLoS ONE 9:e101370. 2014
    ..The negative influence of one improper stiffness can be compensated by adjustment of the stiffness in the other direction. ..
  18. doi request reprint Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD)
    Ronny Bindl
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Helmholtzstr 14, 89081, Ulm, Germany
    J Orthop Res 31:1851-7. 2013
    ..Our results indicate that fracture healing requires central regulation and that thyroxine T4 and 17β-estradiol contribute to the complex pathomechanisms of delayed metaphyseal bone healing in HPD-sheep...
  19. doi request reprint Fracture healing in mice under controlled rigid and flexible conditions using an adjustable external fixator
    Viktoria Röntgen
    Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research, University of Ulm, Ulm, Germany
    J Orthop Res 28:1456-62. 2010
    ..In summary, flexible external fracture fixation of the mouse femur led to delayed fracture healing in comparison to a more rigid situation...