J Weglage

Summary

Country: Germany

Publications

  1. ncbi request reprint Behavioural and emotional problems in early-treated adolescents with phenylketonuria in comparison with diabetic patients and healthy controls
    J Weglage
    Department of Pediatrics, University of Munster, Germany
    J Inherit Metab Dis 23:487-96. 2000
  2. ncbi request reprint Normal clinical outcome in untreated subjects with mild hyperphenylalaninemia
    J Weglage
    Department of Pediatrics, University of Munster, Albert Schweitzer Str 33, 48129 Munster, Germany
    Pediatr Res 49:532-6. 2001
  3. ncbi request reprint Individual blood-brain barrier phenylalanine transport determines clinical outcome in phenylketonuria
    J Weglage
    Department of Pediatrics, University of Munster, Germany
    Ann Neurol 50:463-7. 2001
  4. ncbi request reprint Tetrahydrobiopterin responsiveness in a large series of phenylketonuria patients
    J Weglage
    Department of Pediatrics, University Hospital of Munster, Germany
    J Inherit Metab Dis 25:321-2. 2002
  5. ncbi request reprint Individual blood-brain barrier phenylalanine transport in siblings with classical phenylketonuria
    J Weglage
    Department of Pediatrics, University of Munster, Munster, Germany
    J Inherit Metab Dis 25:431-6. 2002
  6. ncbi request reprint Frontal lobe-dependent functions in treated phenylketonuria: blood phenylalanine concentrations and long-term deficits in adolescents and young adults
    R Feldmann
    Department of Pediatrics, University of Munster, Munster, Germany
    J Inherit Metab Dis 28:445-55. 2005
  7. ncbi request reprint Neurocognitive functioning in adults with phenylketonuria: results of a long term study
    J Weglage
    University of Munster, Department of Pediatrics, Albert Schweitzer Campus 1, 48149 Munster, Germany
    Mol Genet Metab 110:S44-8. 2013
  8. ncbi request reprint In vivo proton magnetic resonance spectroscopy in phenylketonuria
    H E Möller
    Institute for Physical Chemistry, University of Munster, Germany
    Eur J Pediatr 159:S121-5. 2000
  9. doi request reprint Cognitive function in patients with epidermolysis bullosa: social adjustment and emotional problems
    R Feldmann
    University Hospital, Pediatrics, Munster, Germany
    Klin Padiatr 224:22-5. 2012
  10. ncbi request reprint [Intelligence, attention, and memory in patients with myasthenia gravis]
    R Feldmann
    Klinik und Poliklinik für Kinder und Jugendmedizin, Universitatsklinikum Munster
    Nervenarzt 76:960, 962-6. 2005

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Behavioural and emotional problems in early-treated adolescents with phenylketonuria in comparison with diabetic patients and healthy controls
    J Weglage
    Department of Pediatrics, University of Munster, Germany
    J Inherit Metab Dis 23:487-96. 2000
    ..Thus, medical treatment should be accompanied by psychological support for the families...
  2. ncbi request reprint Normal clinical outcome in untreated subjects with mild hyperphenylalaninemia
    J Weglage
    Department of Pediatrics, University of Munster, Albert Schweitzer Str 33, 48129 Munster, Germany
    Pediatr Res 49:532-6. 2001
    ..Nevertheless, problems of maternal phenylketonuria should still be taken into account...
  3. ncbi request reprint Individual blood-brain barrier phenylalanine transport determines clinical outcome in phenylketonuria
    J Weglage
    Department of Pediatrics, University of Munster, Germany
    Ann Neurol 50:463-7. 2001
    ..This observation may lead to individual dietary recommendations in the future...
  4. ncbi request reprint Tetrahydrobiopterin responsiveness in a large series of phenylketonuria patients
    J Weglage
    Department of Pediatrics, University Hospital of Munster, Germany
    J Inherit Metab Dis 25:321-2. 2002
    ..In a group of 87 consecutive patients with hyperphenylalaninaemia born since 1990, only 3 patients showed a (temporary) decrease of serum phenylalanine levels after tetrahydrobiopterin (BH4) loading in usual doses (20 mg/kg body weight)...
  5. ncbi request reprint Individual blood-brain barrier phenylalanine transport in siblings with classical phenylketonuria
    J Weglage
    Department of Pediatrics, University of Munster, Munster, Germany
    J Inherit Metab Dis 25:431-6. 2002
    ..The results indicate that blood-brain barrier transport characteristics and the resultant brain phenylalanine levels are causative factors for the individual clinical outcome in PKU...
  6. ncbi request reprint Frontal lobe-dependent functions in treated phenylketonuria: blood phenylalanine concentrations and long-term deficits in adolescents and young adults
    R Feldmann
    Department of Pediatrics, University of Munster, Munster, Germany
    J Inherit Metab Dis 28:445-55. 2005
    ..Elevated phenylalanine concentrations seem to exert a global effect slowing performance speed. This effect is enduring in adolescence and early adulthood...
  7. ncbi request reprint Neurocognitive functioning in adults with phenylketonuria: results of a long term study
    J Weglage
    University of Munster, Department of Pediatrics, Albert Schweitzer Campus 1, 48149 Munster, Germany
    Mol Genet Metab 110:S44-8. 2013
    ..A controlled long-term study was performed to assess the neurological and neuropsychological performance in adult patients with early-treated phenylketonuria (PKU)...
  8. ncbi request reprint In vivo proton magnetic resonance spectroscopy in phenylketonuria
    H E Möller
    Institute for Physical Chemistry, University of Munster, Germany
    Eur J Pediatr 159:S121-5. 2000
    ..In single cases of untreated, normal intelligent patients, abnormally low [Phe]brain < or = 0.15 mmol/l were observed despite high stationary Phe levels ([Phe]blood = 1.15 +/- 0.10 mmol/l)...
  9. doi request reprint Cognitive function in patients with epidermolysis bullosa: social adjustment and emotional problems
    R Feldmann
    University Hospital, Pediatrics, Munster, Germany
    Klin Padiatr 224:22-5. 2012
    ..Children with Epidermolysis bullosa (EB) suffer from an intractable, burdensome skin disease that may result in cognitive as well as social and emotional problems...
  10. ncbi request reprint [Intelligence, attention, and memory in patients with myasthenia gravis]
    R Feldmann
    Klinik und Poliklinik für Kinder und Jugendmedizin, Universitatsklinikum Munster
    Nervenarzt 76:960, 962-6. 2005
    ..Performance on memory tasks has been reported to correlate with disease activity, but memory in MG patients was also recently found to be unimpaired...
  11. ncbi request reprint Neurofibromatosis type 1: motor and cognitive function and T2-weighted MRI hyperintensities
    R Feldmann
    Department of Pediatrics, University Hospital of Munster, Germany
    Neurology 61:1725-8. 2003
    ..More than 50% of patients with NF1 show focal areas of high signal intensity (T2H) on T2-weighted MRI of the brain. It has been hypothesized that T2H may be associated with the cognitive and motor problems...
  12. ncbi request reprint Investigation of the cerebral energy status in patients with glutaric aciduria type I by 31P magnetic resonance spectroscopy
    H E Möller
    Max Planck Institut für neuropsychologische Forschung, Leipzig, Germany
    Neuropediatrics 34:57-60. 2003
    ..However, as MRS was performed during stable clinical conditions, the possibility of a PCr decrease during acute metabolic crises cannot be assessed...