B Watzl

Summary

Country: Germany

Publications

  1. ncbi Short-term moderate aflatoxin B1 exposure has only minor effects on the gut-associated lymphoid tissue of Brown Norway rats
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Toxicology 138:93-102. 1999
  2. ncbi Daily moderate amounts of red wine or alcohol have no effect on the immune system of healthy men
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Eur J Clin Nutr 58:40-5. 2004
  3. ncbi Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Haid und Neu Strasse 9, DE 76131 Karlsruhe, Germany
    Ann Nutr Metab 47:255-61. 2003
  4. ncbi Acute intake of moderate amounts of red wine or alcohol has no effect on the immune system of healthy men
    Bernhard Watzl
    Institute for Nutritional Physiology, Federal Research Centre for Nutrition, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    Eur J Nutr 41:264-70. 2002
  5. ncbi Inulin, oligofructose and immunomodulation
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Br J Nutr 93:S49-55. 2005
  6. ncbi Dietary wheat germ agglutinin modulates ovalbumin-induced immune responses in Brown Norway rats
    B Watzl
    Institute of Nutritional Physiology, Institute of Hygiene and Toxicology, Federal Research Centre for Nutrition, Haid und Neu Str, 9, 76131 Karlsruhe, Germany
    Br J Nutr 85:483-90. 2001
  7. ncbi Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Br J Nutr 82:383-9. 1999
  8. ncbi Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice
    A Bub
    Institute for Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Eur J Nutr 40:113-20. 2001
  9. ncbi Prolonged tomato juice consumption has no effect on cell-mediated immunity of well-nourished elderly men and women
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    J Nutr 130:1719-23. 2000
  10. ncbi Cloudy apple juice decreases DNA damage, hyperproliferation and aberrant crypt foci development in the distal colon of DMH-initiated rats
    S W Barth
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Carcinogenesis 26:1414-21. 2005

Collaborators

Detail Information

Publications30

  1. ncbi Short-term moderate aflatoxin B1 exposure has only minor effects on the gut-associated lymphoid tissue of Brown Norway rats
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Toxicology 138:93-102. 1999
    ..The low exposure, as it may predominantly occur in western countries, does not appear to increase the risk for sensitization to dietary antigens...
  2. ncbi Daily moderate amounts of red wine or alcohol have no effect on the immune system of healthy men
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Eur J Clin Nutr 58:40-5. 2004
    ..To investigate whether the daily intake of red wine (RW) at a dose which inversely correlates with cardiovascular disease (CVD) risk modulates immune functions in healthy men...
  3. ncbi Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Haid und Neu Strasse 9, DE 76131 Karlsruhe, Germany
    Ann Nutr Metab 47:255-61. 2003
    ....
  4. ncbi Acute intake of moderate amounts of red wine or alcohol has no effect on the immune system of healthy men
    Bernhard Watzl
    Institute for Nutritional Physiology, Federal Research Centre for Nutrition, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    Eur J Nutr 41:264-70. 2002
    ..In contrast, wine constituents such as ethanol and polyphenols are known to suppress immunity...
  5. ncbi Inulin, oligofructose and immunomodulation
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Br J Nutr 93:S49-55. 2005
    ..Human studies are needed to find out whether IN/OF have the potential to modulate systemic immunity in well-nourished individuals and to lower the risk of diseases such as colon cancer...
  6. ncbi Dietary wheat germ agglutinin modulates ovalbumin-induced immune responses in Brown Norway rats
    B Watzl
    Institute of Nutritional Physiology, Institute of Hygiene and Toxicology, Federal Research Centre for Nutrition, Haid und Neu Str, 9, 76131 Karlsruhe, Germany
    Br J Nutr 85:483-90. 2001
    ..In conclusion, these data suggest that high dietary intake of lectins such as WGA may affect the allergic response towards oral antigens in the gut-associated lymphoid tissue...
  7. ncbi Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Br J Nutr 82:383-9. 1999
    ..This modulation could not be explained by changes in the plasma carotenoid concentrations. The active constituents in tomato juice as well as the biological significance of this immunomodulation remain to be determined...
  8. ncbi Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice
    A Bub
    Institute for Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    Eur J Nutr 40:113-20. 2001
    ....
  9. ncbi Prolonged tomato juice consumption has no effect on cell-mediated immunity of well-nourished elderly men and women
    B Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    J Nutr 130:1719-23. 2000
    ..In conclusion, these results show that prolonged tomato juice consumption increased plasma lycopene concentrations without significantly affecting cell-mediated immunity in well-nourished elderly subjects...
  10. ncbi Cloudy apple juice decreases DNA damage, hyperproliferation and aberrant crypt foci development in the distal colon of DMH-initiated rats
    S W Barth
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Carcinogenesis 26:1414-21. 2005
    ..Since both formulations contained comparable concentrations and types of monomeric polyphenols, complex polyphenols or non-polyphenolic compounds, such as pectin might be responsible for the stronger cancer-preventive effect by CloA...
  11. ncbi Modulation of innate and adaptive immunity by the probiotic Bifidobacterium longum PCB133 in turkeys
    S Seifert
    Department of Physiology and Biochemistry of Nutrition, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
    Poult Sci 90:2275-80. 2011
    ..In conclusion, first scientific evidence on the application of the probiotic strain B. longum PCB133 in turkeys beginning at 2 wk of age does not support an improvement in live performance, humoral immunity, or innate immunity...
  12. ncbi PASSCLAIM--gut health and immunity
    John H Cummings
    Pathology and Neuroscience, University of Dundee Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Eur J Nutr 43:II118-II173. 2004
    ..g. change in antibody in blood or response to antigens. determining the incidence and severity of infection in target populations during naturally occurring episodes or in response to attenuated pathogens...
  13. ncbi No differences in DNA damage and antioxidant capacity between intervention groups of healthy, nonsmoking men receiving 2, 5, or 8 servings/day of vegetables and fruit
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Nutr Cancer 60:164-70. 2008
    ....
  14. ncbi Inulin and oligofructose: review of experimental data on immune modulation
    Stephanie Seifert
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, 76131 Karlsruhe, Germany
    J Nutr 137:2563S-2567S. 2007
    ....
  15. ncbi Effect of consumption of organically and conventionally produced apples on antioxidant activity and DNA damage in humans
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, D 76131 Karlsruhe, Germany
    J Agric Food Chem 55:7716-21. 2007
    ....
  16. ncbi Consumption of prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis has minor effects on selected immune parameters in polypectomised and colon cancer patients
    Monika Roller
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Str 9, D 76131 Karlsruhe, Germany
    Br J Nutr 97:676-84. 2007
    ..In conclusion, supplementation with this SYN has minor stimulatory effects on the systemic immune system of the two study groups. Further studies in humans should aim to focus on the gut-associated immune system...
  17. ncbi Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients
    Joseph Rafter
    Department of Medical Nutrition, Karolinska Institutet, Huddinge, Sweden, University College Cork, Cork, Ireland
    Am J Clin Nutr 85:488-96. 2007
    ..Animal studies suggest that prebiotics and probiotics exert protective effects against tumor development in the colon, but human data supporting this suggestion are weak...
  18. ncbi Cloudy apple juice is more effective than apple polyphenols and an apple juice derived cloud fraction in a rat model of colon carcinogenesis
    Stephan W Barth
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    J Agric Food Chem 55:1181-7. 2007
    ..These results demonstrate that CloA had a higher cancer-preventive potential than the fractions and further, besides PF, identified CF as an additional bioactive fraction of CloA...
  19. ncbi A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Redox Rep 10:325-31. 2005
    ....
  20. ncbi A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men
    Bernhard Watzl
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Am J Clin Nutr 82:1052-8. 2005
    ..Whether different intakes of vegetables and fruit modulate immunologic markers is currently not known...
  21. ncbi Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in healthy young men on a low-carotenoid diet supplemented with tomato juice
    Achim Bub
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid und Neu Str 9, Karlsruhe, Germany
    Br J Nutr 93:291-7. 2005
    ....
  22. ncbi Effects of supplementing a low-carotenoid diet with a tomato extract for 2 weeks on endogenous levels of DNA single strand breaks and immune functions in healthy non-smokers and smokers
    Karlis Briviba
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Carcinogenesis 25:2373-8. 2004
    ..009)...
  23. ncbi Intestinal immunity of rats with colon cancer is modulated by oligofructose-enriched inulin combined with Lactobacillus rhamnosus and Bifidobacterium lactis
    Monika Roller
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition and Food, Haid-und-Neu-Str. 9, 76131 Karlsruhe, Germany
    Br J Nutr 92:931-8. 2004
    ..PRE and PRO provided in combination as SYN may contribute to the suppression of colon carcinogenesis by modulating the gut-associated lymphoid tissue...
  24. ncbi Prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis modulates intestinal immune functions in rats
    Monika Roller
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Karlsruhe, Germany
    J Nutr 134:153-6. 2004
    ..The combined application of PRO and PRE has different effects from those of the individual supplements, but does not simply result in additive or synergistic effects...
  25. ncbi Fruit juice consumption modulates antioxidative status, immune status and DNA damage
    Achim Bub
    Institute of Nutritional Physiology, Federal Research Centre for Nutrition, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    J Nutr Biochem 14:90-8. 2003
    ..Further studies should focus on the time-delay between juice intake and changes in measured physiological functions, as well as on active polyphenolic metabolites mediating the observed effects...
  26. ncbi Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in R-allele-carrier but not in QQ homozygous elderly subjects on a tomato-rich diet
    Achim Bub
    Federal Research Centre for Nutrition, Institute of Nutritional Physiology, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    Eur J Nutr 41:237-43. 2002
    ..Paraoxonase (PON1) protects LDL from oxidation and may therefore retard the development of atherosclerosis. The PON1-192 polymorphism is associated with diminished PON1 concentrations and an increased risk for CHD in RR-allele subjects...
  27. ncbi Adhesive and chemokine stimulatory properties of potentially probiotic Lactobacillus strains
    Maria G Vizoso Pinto
    Institute of Hygiene and Toxicology, Federal Research Centre for Nutrition and Food, Haid und Neu Strasse 9, D 76131 Karlsruhe, Germany
    J Food Prot 70:125-34. 2007
    ..johnsonii BFE 6128 showed good adherence, coaggregated with pathogens, and stimulated chemokine production of intestinal epithelial cells, traits that may be considered promising for their development as probiotic strains...
  28. ncbi Consumption of vegetables and fruits and risk of breast cancer
    Bernhard Watzl
    JAMA 293:2209-10; author reply 2210. 2005
  29. ncbi Obesity-related promotion of aberrant crypt foci in DMH-treated obese Zucker rats correlates with dyslipidemia rather than hyperinsulinemia
    Tatiana C L Koch
    Department of Nutritional Physiology and Biochemistry, Max Rubner Institute, Haid und Neu Strasse 9, 76131 Karlsruhe, Germany
    Eur J Nutr 47:161-70. 2008
    ..Obesity and energy restriction modulate the development of precancerous aberrant crypt foci (ACF) in animal models of colon cancer...
  30. ncbi Markers to measure immunomodulation in human nutrition intervention studies
    Ruud Albers
    Unilever Health Institute, PO Box 114, NL 3130 AC Vlaardingen, The Netherlands
    Br J Nutr 94:452-81. 2005
    ..It would be valuable to include several immune markers in addition to clinical outcome in future clinical trials in this area, as there is too little evidence that correlates markers with global health improvement...