Dirk Vordermark

Summary

Country: Germany

Publications

  1. ncbi 3-D reconstruction of anterior mantle-field techniques in Hodgkin's disease survivors: doses to cardiac structures
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Germany
    Radiat Oncol 1:10. 2006
  2. ncbi Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26)
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Wurzburg, Germany
    BMC Cancer 6:247. 2006
  3. ncbi Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Strahlenther Onkol 179:801-11. 2003
  4. ncbi Glucose requirement for hypoxic accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha)
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Josef Schneider Str 11, 97080 Wurzburg, Germany
    Cancer Lett 230:122-33. 2005
  5. ncbi Patterns of care in the radiotherapy of prostate cancer in Northern Bavaria 1998-2000
    Dirk Vordermark
    Department of Radiation Oncology, University of Wuerzburg, Josef Schneider Strasse 11, 97080 Wurzburg, Germany
    Strahlenther Onkol 183:314-20. 2007
  6. ncbi Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Germany
    BMC Cancer 5:55. 2005
  7. ncbi Local control in 118 consecutive high-risk breast cancer patients treated with breast-conserving therapy
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, 97080 Wurzburg, Germany
    Oncol Rep 18:1335-9. 2007
  8. ncbi Prospective evaluation of quality of life after permanent prostate brachytherapy with I-125: importance of baseline symptoms and of prostate-V150
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Radiother Oncol 91:217-24. 2009
  9. ncbi Plasma osteopontin levels in patients with head and neck cancer and cervix cancer are critically dependent on the choice of ELISA system
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Germany
    BMC Cancer 6:207. 2006
  10. ncbi 3-D conformal treatment of prostate cancer to 74 Gy vs. high-dose-rate brachytherapy boost: a cross-sectional quality-of-life survey
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Acta Oncol 45:708-16. 2006

Detail Information

Publications67

  1. ncbi 3-D reconstruction of anterior mantle-field techniques in Hodgkin's disease survivors: doses to cardiac structures
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Germany
    Radiat Oncol 1:10. 2006
    ..Dose-volume histograms (DVHs) were generated for these heart structures and results compared between techniques...
  2. ncbi Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26)
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Wurzburg, Germany
    BMC Cancer 6:247. 2006
    ....
  3. ncbi Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Strahlenther Onkol 179:801-11. 2003
    ..Recently, the immunohistochemical detection of proteins involved in the "hypoxic response" of tumor cells has been discussed as a method to estimate hypoxia in clinical tumor specimens...
  4. ncbi Glucose requirement for hypoxic accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha)
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Josef Schneider Str 11, 97080 Wurzburg, Germany
    Cancer Lett 230:122-33. 2005
    ..This glucose effect was confirmed in a hypoxia-responsive-element (HRE)/enhanced-green-fluorescent-protein (EGFP) reporter assay in transfected HT 1080 cells and possibly explains a lack of HIF-1alpha protein in hypoxic tumor cells...
  5. ncbi Patterns of care in the radiotherapy of prostate cancer in Northern Bavaria 1998-2000
    Dirk Vordermark
    Department of Radiation Oncology, University of Wuerzburg, Josef Schneider Strasse 11, 97080 Wurzburg, Germany
    Strahlenther Onkol 183:314-20. 2007
    ..A patterns-of-care study of radiotherapy (RT) in prostate cancer was performed in Northern Bavaria, Germany, to characterize patient selection, treatment strategies and outcome for the time period 1998-2000...
  6. ncbi Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Germany
    BMC Cancer 5:55. 2005
    ..Hypofractionated stereotactic radiotherapy (HFSRT) is one salvage treatment option in previously irradiated patients with recurrent malignant glioma. We analyzed the results of HFSRT and prognostic factors in a single-institution series...
  7. ncbi Local control in 118 consecutive high-risk breast cancer patients treated with breast-conserving therapy
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, 97080 Wurzburg, Germany
    Oncol Rep 18:1335-9. 2007
    ..Younger patients and patients who received adjuvant chemotherapy (due to the presence of histopathological risk factors) were at increased risk of in-breast recurrence and should be considered for intensified local treatment...
  8. ncbi Prospective evaluation of quality of life after permanent prostate brachytherapy with I-125: importance of baseline symptoms and of prostate-V150
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Radiother Oncol 91:217-24. 2009
    ..Detailed knowledge of quality of life (QoL) after permanent I-125 brachytherapy may aid in counselling patients with early-stage prostate cancer...
  9. ncbi Plasma osteopontin levels in patients with head and neck cancer and cervix cancer are critically dependent on the choice of ELISA system
    Dirk Vordermark
    Dept of Radiation Oncology, University of Wurzburg, Germany
    BMC Cancer 6:207. 2006
    ..The clinical introduction of plasma OPN measurements requires the availability of a reliable enzyme-linked immunosorbence assay (ELISA)...
  10. ncbi 3-D conformal treatment of prostate cancer to 74 Gy vs. high-dose-rate brachytherapy boost: a cross-sectional quality-of-life survey
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Acta Oncol 45:708-16. 2006
    ..Dose escalation in prostate cancer by either 3-DC boost to 74 Gy or HDR brachytherapy boost appears to result in similar HRQOL profiles...
  11. ncbi Cell type-specific association of hypoxia-inducible factor-1 alpha (HIF-1 alpha) protein accumulation and radiobiologic tumor hypoxia
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Wurzburg, Germany
    Int J Radiat Oncol Biol Phys 58:1242-50. 2004
    ..To explain this discrepancy, we studied the in vitro conditions under which HIF-1 alpha protein accumulates...
  12. ncbi Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo
    Harun M Said
    Department of Radiation Oncology, University of Wurzburg, D 97080 Wurzburg, Germany
    Oncol Rep 21:237-46. 2009
    ....
  13. ncbi Rapid detection of the hypoxia-regulated CA-IX and NDRG1 gene expression in different glioblastoma cells in vitro
    Harun M Said
    Department of Radiation Oncology, University of Wurzburg, 97080 Wurzburg, Germany
    Oncol Rep 20:413-9. 2008
    ....
  14. ncbi Effects of HIF-1 inhibition by chetomin on hypoxia-related transcription and radiosensitivity in HT 1080 human fibrosarcoma cells
    Adrian Staab
    Department of Radiation Oncology, University of Wurzburg, 97080 Wurzburg, Germany
    BMC Cancer 7:213. 2007
    ..We investigated whether targeting of HIF-1 using chetomin, a disrupter of the interaction of HIF-1 with the transcriptional coactivator p300, influences the radiosensitivity of hypoxic HT 1080 human fibrosarcoma cells...
  15. ncbi Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoietin, VEGF and HIF-1alpha in human glioma in vitro and in vivo
    Harun M Said
    Department of Radiation Oncology, University of Wurzburg, Germany
    Radiother Oncol 83:398-405. 2007
    ....
  16. ncbi Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro
    Adrian Staab
    Department of Radiation Oncology, University of Wurzburg, Wurzburg, Germany
    Strahlenther Onkol 187:252-9. 2011
    ....
  17. ncbi Distinct effects of rectum delineation methods in 3D-conformal vs. IMRT treatment planning of prostate cancer
    Matthias Guckenberger
    Department of Radiation Oncology, University of Wuerzburg, Josef Schneider Str, 11, 97080 Wuerzburg, Germany
    Radiat Oncol 1:34. 2006
    ..The dose distribution to the rectum, delineated as solid organ, rectal wall and rectal surface, in 3D conformal (3D-CRT) and intensity-modulated radiotherapy treatment (IMRT) planning for localized prostate cancer was evaluated...
  18. ncbi Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas
    Carsten Hagemann
    Department of Neurosurgery, University of Wurzburg, D 97080 Wurzburg, Germany
    Oncol Rep 20:301-8. 2008
    ..Our findings are significant as the expression of ASPM may be used as a marker for glioma malignancy and represents a potential therapeutic target...
  19. ncbi GAPDH is not regulated in human glioblastoma under hypoxic conditions
    Harun M Said
    University of Wurzburg, Dept of Radiation Oncology, Germany
    BMC Mol Biol 8:55. 2007
    ..HIF-1alpha protein regulation under hypoxia was also determined on mRNA level in vitro in GaMG and on protein level in U251, U373 and GaMG cells...
  20. ncbi Does intensity modulated radiation therapy (IMRT) prevent additional toxicity of treating the pelvic lymph nodes compared to treatment of the prostate only?
    Matthias Guckenberger
    Department of Radiation Oncology, Julius Maximilians University, Wuerzburg, Germany
    Radiat Oncol 3:3. 2008
    ..To evaluate the risk of rectal, bladder and small bowel toxicity in intensity modulated radiation therapy (IMRT) of the prostate only compared to additional irradiation of the pelvic lymphatic region...
  21. ncbi Distinct patterns of hypoxic expression of carbonic anhydrase IX (CA IX) in human malignant glioma cell lines
    Harun M Said
    Department of Radiation Oncology, University of Wuerzburg, Josef Schneider Strasse 11, 97080 Wuerzburg, Germany
    J Neurooncol 81:27-38. 2007
    ..Therefore, immunohistochemical CA IX staining in human malignant glioma specimens can result from low oxygen concentrations or constitutive, oncogene-related, overexpression both of which may be prognostically relevant...
  22. ncbi Precision required for dose-escalated treatment of spinal metastases and implications for image-guided radiation therapy (IGRT)
    Matthias Guckenberger
    Department of Radiation Oncology, University of Wuerzburg, Wuerzburg, Germany
    Radiother Oncol 84:56-63. 2007
    ..To evaluate the precision required in dose-escalated IMRT treatment of spinal metastases and paraspinal tumors...
  23. ncbi Influence of rectum delineation (rectal volume vs. rectal wall) on IMRT treatment planning of the prostate
    Matthias Guckenberger
    Department of Radiation Oncology, University of Wuerzburg, Wuerzburg, Germany
    Strahlenther Onkol 182:721-6. 2006
    ..To evaluate the delineation of either the rectal volume (RV) or the rectal wall (RW) in intensity-modulated radiotherapy (IMRT) for prostate cancer: influence on dose distribution to the targets and organs at risk (OARs) was investigated...
  24. ncbi Modulation of carbonic anhydrase 9 (CA9) in human brain cancer
    Harun M Said
    Department of Radiation, Oncology, University of Wurzburg, Josef Schneider Strasse 11, Wurzburg, Germany
    Curr Pharm Des 16:3288-99. 2010
    ....
  25. ncbi Cardiac magnetic resonance imaging findings in 20-year survivors of mediastinal radiotherapy for Hodgkin's disease
    Wolfram Machann
    Department of Radiology, University of Wurzburg, Wurzburg, Germany
    Int J Radiat Oncol Biol Phys 79:1117-23. 2011
    ..Cardiac magnetic resonance imaging (MRI) permits excellent quantification of cardiac function and identification of localized myocardial defects and has now been applied to a group of 20-year Hodgkin's disease survivors...
  26. ncbi RAF expression in human astrocytic tumors
    Carsten Hagemann
    Department of Neurosurgery, Tumorbiology Laboratory, University of Wurzburg, D 97080 Wurzburg, Germany
    Int J Mol Med 23:17-31. 2009
    ..Our data indicate that RAF proteins might be valuable targets for small molecule therapies. However, initially specific functions of RAF during tumorigenesis have to be elucidated...
  27. ncbi Reliability of the bony anatomy in image-guided stereotactic radiotherapy of brain metastases
    Matthias Guckenberger
    Department of Radiation Oncology, Julius Maximilians University, Wuerzburg, Germany
    Int J Radiat Oncol Biol Phys 69:294-301. 2007
    ..To evaluate whether the position of brain metastases remains stable between planning and treatment in cranial stereotactic radiotherapy (SRT)...
  28. ncbi Characterization of carbonic anhydrase IX (CA IX) as an endogenous marker of chronic hypoxia in live human tumor cells
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Josef Schneider Str, 97080 Wurzburg, Germany
    Int J Radiat Oncol Biol Phys 61:1197-207. 2005
    ....
  29. ncbi Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells
    Harun M Said
    Harun M Said, Buelent Polat, Mathias Guckenberger, Adrian Staab, Astrid Katzer, Michael Flentje, Dirk Vordermark, Department of Radiation Oncology, University of Wuerzburg, 97080 Wurzburg, Germany
    World J Clin Oncol 3:104-10. 2012
    ....
  30. ncbi Modulation of glucose metabolism inhibits hypoxic accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha)
    Adrian Staab
    Department of Radiotherapy, University of Wuerzburg, Germany
    Strahlenther Onkol 183:366-73. 2007
    ..The aim of this study was to investigate the underlying mechanism of this effect...
  31. ncbi Association of anorectal dose-volume histograms and impaired fecal continence after 3D conformal radiotherapy for carcinoma of the prostate
    Dirk Vordermark
    Department of Radiation Oncology, , Josef-Schneider-Street 11, , Germany
    Radiother Oncol 69:209-14. 2003
    ..CONCLUSIONS: Excluding the inferior part of the anal canal from the treated volume in 3D conformal therapy for carcinoma of the prostate appears to be a promising strategy to prevent radiation-induced fecal incontinence...
  32. ncbi Response of the plasma hypoxia marker osteopontin to in vitro hypoxia in human tumor cells
    Harun M Said
    Department of Radiation Oncology, , , Germany
    Radiother Oncol 76:200-5. 2005
    ..OPN mRNA response to hypoxia and reoxygenation was very heterogeneous between cell lines. CONCLUSION: Reoxygenation rather than hypoxia appears to induce OPN secretion from human tumor cells in a cell-type specific manner...
  33. ncbi Steep dose gradients for simultaneous integrated boost IMRT
    Klaus Bratengeier
    Universitat Wurzburg, Klinik und Poliklinik für Strahlentherapie, Josef Schneider Str 11, D 97080 Wurzburg, Germany
    Z Med Phys 19:129-35. 2009
    ..The segment numbers were lower or equal--with better sparing of the surrounding tissue. In summary, it was demonstrated that 2-Step IMRT was able to achieve steep dose gradients for SIB constellations...
  34. ncbi Target motion measurement without implanted markers and its validation by comparison with manually obtained data
    Lucia Vences
    , , Josef-Schneider-Str. 11, , Germany
    Med Phys 32:3431-9. 2005
    ..The results of this novel method were validated by comparison with manually determined target position...
  35. ncbi Magnitude and clinical relevance of translational and rotational patient setup errors: a cone-beam CT study
    Matthias Guckenberger
    Department of Radiation Oncology, University of Wuerzburg, Wuerzburg, Germany
    Int J Radiat Oncol Biol Phys 65:934-42. 2006
    ..To establish volume imaging using an on-board cone-beam CT (CB-CT) scanner for evaluation of three-dimensional patient setup errors...
  36. ncbi Chronic fatigue after radiotherapy for carcinoma of the prostate: correlation with anorectal and genitourinary function
    Dirk Vordermark
    Department of Radiation Oncology, , Josef-Schneider-Strasse 11, Germany
    Radiother Oncol 62:293-7. 2002
    ..2+/-1.8 and 5%, respectively). Fatigue was significantly correlated with fecal incontinence and urinary symptoms, suggesting an association of chronic fatigue and late radiation toxicity in carcinoma of the prostate...
  37. ncbi Adverse effect of a distended rectum in intensity-modulated radiotherapy (IMRT) treatment planning of prostate cancer
    Matthias Guckenberger
    Department of Radiation Oncology, University of Wuerzburg, Germany
    Radiother Oncol 79:59-64. 2006
    ....
  38. ncbi Egr-1 is not upregulated in response to hypoxic and oxygenation conditions in human glioblastoma in vitro
    Harun M Said
    Department of Radiation Oncology, University of W rzburg, 97080 W rzburg, Germany
    Mol Med Report 2:757-63. 2009
    ....
  39. ncbi Hypoxia-specific targets in cancer therapy: role of splice variants
    Dirk Vordermark
    Department of Radiation Oncology, Martin Luther University Halle Wittenberg, Germany
    BMC Med 8:45. 2010
    ..This preliminary study addresses the possibility that specific targeting of individual isoforms resulting from alternative splicing may play a role in HIF-1-directed treatment approaches...
  40. ncbi Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro
    Harun M Said
    Department of Radiation Oncology, Faculty of Medicine, , , Germany
    BMC Res Notes 2:8. 2009
    ..The results confirm our previous findings in human glioblastoma that this gene is not an attractive target for tumor therapeutic approaches because of the lack of GAPDH regulation under hypoxia...
  41. ncbi Impaired sphincter function and good quality of life in anal carcinoma patients after radiotherapy: a paradox?
    Dirk Vordermark
    Department of Radiation Oncology, University of Wurzburg, Germany
    Front Radiat Ther Oncol 37:132-9. 2002
  42. ncbi The relationship between belly board position and patient anatomy and its influence on dose-volume histogram of small bowel for postoperative radiotherapy of rectal cancer
    Oliver Koelbl
    Department of Radiotherapy, University of Wuerzburg, Josef-Schneider-Strasse 11, 97080 Wuerzburg, Germany
    Radiother Oncol 67:345-9. 2003
    ....
  43. ncbi Evaluation of hypoxia-inducible factor-1alpha (HIF-1alpha) as an intrinsic marker of tumor hypoxia in U87 MG human glioblastoma: in vitro and xenograft studies
    Dirk Vordermark
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA
    Int J Radiat Oncol Biol Phys 56:1184-93. 2003
    ..High protein levels have been linked to poor prognosis in several tumor types, and HIF-1alpha has been suggested as a potential endogenous marker of tumor hypoxia and associated radioresistance...
  44. ncbi Ten years of progress in radiation oncology
    Dirk Vordermark
    Department of Radiation Oncology, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    BMC Cancer 11:503. 2011
    ....
  45. ncbi Secretory activity and cell cycle alteration of alveolar type II cells in the early and late phase after irradiation
    Jochen Willner
    Department of Radiotherapy, University of Wuerzburg, Wuerzburg, Germany
    Int J Radiat Oncol Biol Phys 55:617-25. 2003
    ..We analyzed the secretory function and proliferation parameters of alveolar type II cells in the early (until 24 h) and late phase (1-5 weeks) after irradiation (RT) in vitro and in vivo...
  46. ncbi Patient information in radiation oncology: a cross-sectional pilot study using the EORTC QLQ-INFO26 module
    Johannes Adler
    Department of Radiation Oncology, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    Radiat Oncol 4:40. 2009
    ..The purpose of the present study was to assess perception of information in cancer patients during radiotherapy as well as media preferences and specifically the utilization of the internet...
  47. ncbi Quality of training in radiation oncology in Germany. Results of a 2006 survey
    Robert Semrau
    Department of Radiation Oncology, University Hospital Cologne, Germany
    Strahlenther Onkol 184:239-44. 2008
    ..To evaluate residents' satisfaction with their training in radiation oncology, the first nationwide survey was done in 2006. Results were presented at the 2006 annual meeting of the German Society of Radiation Oncology (DEGRO)...
  48. ncbi Radiation therapy and internet - what can patients expect? homepage analysis of german radiotherapy institutions
    Stefan Janssen
    Department of Radiation Oncology, Medical School Hannover, Hannover, Germany
    Strahlenther Onkol 186:700-4. 2010
    ..There is a confusing amount of medical websites with a great diversity of quality. Websites of radiotherapy institutions could offer a safe and an easy-to-control way to assist patients' requests...
  49. ncbi Temporal changes in quality of life (QoL) of patients with primary brain tumors: raw QoL data from a randomized trial as reference for future studies
    Dirk Vordermark
    J Clin Oncol 26:2061-2; author reply 2062. 2008
  50. ncbi Radiotherapy of prostate cancer with multileaf collimators (MLCs) optimization of the undulating dose distribution at the MLC edge
    Oliver Koelbl
    Department of Radiotherapy, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Strahlenther Onkol 181:108-12. 2005
    ..A technical modification for radiotherapy of prostate cancer is presented to smooth the scalloped dose pattern that occurs at treatment field edge, when a multileaf collimator (MLC) has been used...
  51. ncbi An experimental evaluation of three preoperative radiation regimens for resectable rectal cancer
    Genc Basha
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Belgium
    Ann Surg Oncol 9:292-7. 2002
    ..CONCLUSIONS: A shorter treatment time offered the best therapeutic efficacy. The schedule involving two daily fractions of 3 Gy over 5 days should be less toxic than 5 x 5 Gy and may therefore provide a therapeutic advantage...
  52. ncbi Lack of survival benefit after stereotactic radiosurgery boost for glioblastoma multiforme: randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients
    Dirk Vordermark
    Int J Radiat Oncol Biol Phys 62:296-7; author reply 297. 2005
  53. ncbi In regard to Kapp et al.: experience with split-course external beam irradiation +/- chemotherapy and integrated (192)Ir high-dose-rate brachytherapy in the treatment of primary carcinomas of the anal canal. IJROBP 2001;49:997--1005
    Dirk Vordermark
    Int J Radiat Oncol Biol Phys 52:580-1. 2002
  54. ncbi Significance of hypoxia in malignant glioma. Re: Evans et al. Hypoxia is important in the biology and aggression of human glial brain tumors. Clin Cancer Res 2004;10:8177-84
    Dirk Vordermark
    Clin Cancer Res 11:3966-7; author reply 3967-8. 2005
  55. ncbi Cardiac toxicity of mediastinal radiotherapy: which are the critical structures?
    Dirk Vordermark
    J Clin Oncol 23:3634-6; author reply 3636. 2005
  56. ncbi Immunohistochemical detection of osteopontin in advanced head-and-neck cancer: prognostic role and correlation with oxygen electrode measurements, hypoxia-inducible-factor-1alpha-related markers, and hemoglobin levels
    Matthias Bache
    Department of Radiotherapy, Martin-Luther-University Halle-Wittenberg, Halle, Germany
    Int J Radiat Oncol Biol Phys 66:1481-7. 2006
    ..When the results of OPN, HIF-1alpha, and CA IX immunohistochemistry are combined into a hypoxic profile, a strong and statistically significant impact on overall survival is found...
  57. ncbi Prophylactic radiotherapy for glioblastoma in the elderly
    Dirk Vordermark
    N Engl J Med 357:195-6; author reply 196. 2007
  58. ncbi Skin-sparing intensity-modulated radiotherapy of the breast
    Dirk Vordermark
    J Clin Oncol 26:3292; author reply 3292-3. 2008
  59. ncbi Transperineal injection of hyaluronic acid in anterior perirectal fat to decrease rectal toxicity from radiation delivered with intensity-modulated brachytherapy or EBRT for prostate cancer patients: in regard to Prada et al. (Int J Radiat Oncol Biol Phys
    Dirk Vordermark
    Int J Radiat Oncol Biol Phys 71:316-7. 2008
  60. ncbi Quality of life and satisfaction with outcome among prostate-cancer survivors
    Dirk Vordermark
    N Engl J Med 359:201; author reply 201-2. 2008
  61. ncbi Potential and limitations of intensity-modulated radiotherapy in anal cancer
    Dirk Vordermark
    J Clin Oncol 26:688; author reply 688-9. 2008
  62. ncbi In regard to DAI et al.: inhibition of hypoxia inducible factor 1alpha causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells. IJROBP 2003;55:1027-1036)
    Dirk Vordermark
    Int J Radiat Oncol Biol Phys 57:1196. 2003
  63. ncbi Immunohistochemical detection of HIF-1alpha and CAIX in advanced head-and-neck cancer. Prognostic role and correlation with tumor markers and tumor oxygenation parameters
    Matthias Kappler
    Department of Radiotherapy, Martin Luther University of Halle Wittenberg, Germany
    Strahlenther Onkol 184:393-9. 2008
    ..Furthermore, the association of these hypoxia markers with tumor markers or tumor oxygenation parameters is of importance for understanding the relationship between the different factors...
  64. ncbi Similar radiation sensitivities of acutely and chronically hypoxic cells in HT 1080 fibrosarcoma xenografts
    Dirk Vordermark
    Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University School of Medicine, CCSR-South, Room 1255, 269 Campus Drive, Stanford, California 94305-5152, USA
    Radiat Res 159:94-101. 2003
    ..We therefore conclude that, at least in this tumor model, the radiation sensitivity of chronically hypoxic cells is similar to that of the acutely hypoxic cells...
  65. ncbi Expression of hypoxia-inducible factor-1alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis
    Dirk Vordermark
    Cancer 94:2317-8; author reply 2318-9. 2002
  66. ncbi Avoiding bias in the prospective evaluation of patients with brain metastases
    Dirk Vordermark
    J Clin Oncol 25:4023; author reply 4024-5. 2007
  67. ncbi Quality of life after treatment for prostate cancer: no difference between surgery and radiotherapy?
    Dirk Vordermark
    J Clin Oncol 21:4655; author reply 4655-6. 2003