Dorothee Viemann

Summary

Country: Germany

Publications

  1. doi H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response
    Dorothee Viemann
    Institute of Immunology, University of Muenster, Muenster, Germany
    J Immunol 186:164-73. 2011
  2. ncbi TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells
    Dorothee Viemann
    Department of Experimental Dermatology and Interdisciplinary Clinical Research Center, University of Munster, Röntgenstr 21, 48149 Munster, Germany
    J Leukoc Biol 80:174-85. 2006
  3. ncbi Expression of toll-like receptors in neonatal sepsis
    Dorothee Viemann
    Department of Pediatrics, University of Munster, Germany
    Pediatr Res 58:654-9. 2005
  4. ncbi Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells
    Dorothee Viemann
    Institute of Experimental Dermatology, Integrated Functional Genomics, and the Interdisciplinary Clinical Research Center, University Hospital Muenster, University of Muenster, Röntgenstrasse 21, 48149 Muenster, Germany
    Blood 105:2955-62. 2005
  5. pmc Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages
    Judith Friesenhagen
    Institute of Immunology, University of Muenster, Muenster, Germany
    J Leukoc Biol 92:11-20. 2012
  6. ncbi Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells
    Dorothee Viemann
    Department of Experimental Dermatology, University Hospital Munster, Muenster, Germany
    Blood 103:3365-73. 2004
  7. ncbi The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappaB and hypoxia-inducible factor-1alpha
    Dorothee Viemann
    Institute of Experimental Dermatology, Interdisciplinary Center of Clinical Research, and Department of Pediatrics, University of Munster, Munster, Germany
    J Immunol 178:3198-207. 2007
  8. ncbi MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program
    Dorothee Viemann
    Institute of Experimental Dermatology, University of Munster, Germany
    Blood 109:2453-60. 2007
  9. doi Endothelial cells present an innate resistance to glucocorticoid treatment: implications for therapy of primary vasculitis
    Paola Koenen
    Institute of Immunology, University of Muenster, Muenster, Germany
    Ann Rheum Dis 71:729-36. 2012
  10. doi Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3
    Katarzyna Barczyk
    Institute of Immunology, University of Muenster, Muenster, Germany
    Blood 116:446-55. 2010

Collaborators

Detail Information

Publications20

  1. doi H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response
    Dorothee Viemann
    Institute of Immunology, University of Muenster, Muenster, Germany
    J Immunol 186:164-73. 2011
    ....
  2. ncbi TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells
    Dorothee Viemann
    Department of Experimental Dermatology and Interdisciplinary Clinical Research Center, University of Munster, Röntgenstr 21, 48149 Munster, Germany
    J Leukoc Biol 80:174-85. 2006
    ..The establishment of EC type-specific expression patterns may thus provide the basis for a selective manipulation of specific endothelial subtypes in different inflammatory diseases...
  3. ncbi Expression of toll-like receptors in neonatal sepsis
    Dorothee Viemann
    Department of Pediatrics, University of Munster, Germany
    Pediatr Res 58:654-9. 2005
    ..The definition of TLR expression patterns might open a new field of therapeutic targets for neonatal sepsis...
  4. ncbi Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells
    Dorothee Viemann
    Institute of Experimental Dermatology, Integrated Functional Genomics, and the Interdisciplinary Clinical Research Center, University Hospital Muenster, University of Muenster, Röntgenstrasse 21, 48149 Muenster, Germany
    Blood 105:2955-62. 2005
    ..MRP8/MRP14 may represent novel targets for anti-inflammatory strategies...
  5. pmc Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages
    Judith Friesenhagen
    Institute of Immunology, University of Muenster, Muenster, Germany
    J Leukoc Biol 92:11-20. 2012
    ..In summary, our data provide first evidences for a strategy of how HPAIVs avoid initial inflammatory responses of macrophages facilitating virus spreading and progression to the systemic stage of disease...
  6. ncbi Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells
    Dorothee Viemann
    Department of Experimental Dermatology, University Hospital Munster, Muenster, Germany
    Blood 103:3365-73. 2004
    ..Thus, these results define a list of primary candidates for targeted modulation of endothelial functions during inflammation...
  7. ncbi The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappaB and hypoxia-inducible factor-1alpha
    Dorothee Viemann
    Institute of Experimental Dermatology, Interdisciplinary Center of Clinical Research, and Department of Pediatrics, University of Munster, Munster, Germany
    J Immunol 178:3198-207. 2007
    ....
  8. ncbi MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program
    Dorothee Viemann
    Institute of Experimental Dermatology, University of Munster, Germany
    Blood 109:2453-60. 2007
    ..Excessive release of cytotoxic MRP8/MRP14 by activated phagocytes might therefore present an important molecular pathomechanism contributing to endothelial damage during vasculitis and other inflammatory diseases...
  9. doi Endothelial cells present an innate resistance to glucocorticoid treatment: implications for therapy of primary vasculitis
    Paola Koenen
    Institute of Immunology, University of Muenster, Muenster, Germany
    Ann Rheum Dis 71:729-36. 2012
    ..In contrast to other chronic inflammatory diseases glucocorticoids alone do not maintain sufficient remission in primary vasculitis. The reasons for this therapeutic failure remain unclear...
  10. doi Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3
    Katarzyna Barczyk
    Institute of Immunology, University of Muenster, Muenster, Germany
    Blood 116:446-55. 2010
    ....
  11. doi Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4
    Dirk Foell
    Department of Pediatric Rheumatology and Immunology, University Children s Hospital Muenster, Muenster, Germany
    Am J Respir Crit Care Med 187:1324-34. 2013
    ..However, the exact role of human S100A12 during early steps of immune activation and sepsis is only partially described thus far...
  12. pmc Keratinocytes determine Th1 immunity during early experimental leishmaniasis
    Jan M Ehrchen
    Institute of Immunology, University of Muenster, Muenster, Germany
    PLoS Pathog 6:e1000871. 2010
    ..Thus, our data indicate for the first time that epidermal cytokine expression is a decisive factor in the generation of protective Th1 immunity and contributes to the outcome of infection with this important human pathogen...
  13. ncbi Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis
    Michael Frosch
    Institute of Experimental Dermatology and Department of Pediatrics, University of Munster, Munster, Germany
    Arthritis Rheum 48:2622-6. 2003
    ....
  14. doi Highly pathogenic influenza viruses inhibit inflammatory response in monocytes via activation of rar-related orphan receptor RORα
    Judith Friesenhagen
    Institute of Immunology, University of Munster, Munster, Germany Friesenhagen Judith mh hannover de
    J Innate Immun 5:505-18. 2013
    ..In summary, our study reveals a novel RORα-dependent escape mechanism by which H5N1 prevents an effective inflammatory response of monocytes blocking NF-κB-dependent gene expression...
  15. doi Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome
    Mirco Schmolke
    Institute of Molecular Virology, Center of Molecular Biology of Inflammation and Interdisciplinary Center of Medical Research, Universitaetsklinikum Muenster, Muenster, Germany
    J Immunol 183:5180-9. 2009
    ..Control experiments with a low pathogenic influenza strain revealed a much weaker and less NF-kappaB-dependent host cell response...
  16. ncbi Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12
    Helmut Wittkowski
    Interdisciplinary Centre for Clinical Research, Department of Pediatrics, University of Muenster, University Hospital, Albert Schweitzer Strasse 33, Muenster, Germany
    Arthritis Rheum 56:4174-81. 2007
    ..The aim of this study was to investigate circulating sRAGE in an acute inflammatory disorder and to compare these data directly with concentrations of the proinflammatory RAGE ligand S100A12...
  17. pmc The cyclic AMP response element modulator {alpha} suppresses CD86 expression and APC function
    Martina Ahlmann
    Institute of Immunology, University of Munster, Germany
    J Immunol 182:4167-74. 2009
    ..We conclude that CREMalpha is an important negative regulator of costimulation and APC-dependent T cell function both in vitro and in vivo...
  18. ncbi Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome
    Helmut Wittkowski
    Department of Pediatrics, Interdisciplinary Center of Clinical Research, Institute of Experimental Dermatology, University of Muenster, Germany
    Crit Care Med 35:1369-75. 2007
    ..Additional in vivo and in vitro experiments were performed to further analyze the contribution of S100A12 to pulmonary inflammation...
  19. ncbi Potentials and pitfalls of DNA array analysis of the endothelial stress response
    Dorothee Viemann
    Institute of Experimental Dermatology, Department of Pediatrics and Integrated Functional Genomics, University of Munster, Röntgenstr 21, Germany
    Biochim Biophys Acta 1746:73-84. 2005
    ..We also attempt to outline some of the caveats and standard criteria that have to be considered in order to realize the full potential of microarrays in inflammation research...
  20. ncbi Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells
    Verena Müller
    Department of Dermatology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany
    J Immunol 179:8435-45. 2007
    ..Our study provides the first comprehensive analysis of endothelial gene responses to C. albicans and presents novel insights into the complex signaling patterns triggered by this important pathogen...