Research Topics
Genomes and Genes | Peter J VerveerSummaryCountry: Germany Publications
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Detail Information
Publications
High-resolution three-dimensional imaging of large specimens with light sheet-based microscopyPeter J Verveer
Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
Nat Methods 4:311-3. 2007..The ability to rapidly image large samples at high resolution with minimal photodamage provides new opportunities especially for the study of subcellular processes in large living specimens...
Quantitative microscopy and systems biology: seeing the whole picturePeter J Verveer
Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto Hahn Strasse 11, 44227, Dortmund, Germany
Histochem Cell Biol 130:833-43. 2008..Combined with computational approaches they allow us to obtain insights in the reaction-diffusion processes that determine biological function on the scale of cells...- Global analysis of time correlated single photon counting FRET-FLIM dataHernan E Grecco
Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto Hahn Strasse 11, 44227 Dortmund, Germany
Opt Express 17:6493-508. 2009..The proposed method is efficient and robust, and can be routinely applied to analyze FRET-FLIM data acquired in intact cells... - An acylation cycle regulates localization and activity of palmitoylated Ras isoformsOliver Rocks
Department of Structural Biology, Max Planck Institute for Molecular Physiology, Otto Hahn Strasse 11, 44227 Dortmund, Germany
Science 307:1746-52. 2005..The de/reacylation cycle also initiates Ras activation at the Golgi by transport of PM-localized Ras guanosine triphosphate. Different de/repalmitoylation kinetics account for isoform-specific activation responses to growth factors... - Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fateSilvia D M Santos
European Molecular Biology Laboratory EMBL, Cell Biology and Biophysics, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
Nat Cell Biol 9:324-30. 2007..These results show that growth factor context determines the topology of the MAPK signalling network and that the resulting dynamics govern cell fate... - FRET in cell biology: still shining in the age of super-resolution?Hernan E Grecco
Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto Hahn Strasse 11, D 44227 Dortmund, Germany
Chemphyschem 12:484-90. 2011..Herein we review the major applications in biological FRET imaging and we discuss the possibilities and challenges in the super-resolution era... - Red-edge anisotropy microscopy enables dynamic imaging of homo-FRET between green fluorescent proteins in cellsAnthony Squire
Cell Biology and Cell Biophysics Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
J Struct Biol 147:62-9. 2004.... - Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulumFawaz G Haj
Cancer Biology Program, Division of Hematology Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
Science 295:1708-11. 2002..Most of the RTKs activated at the cell surface showed interaction with PTP1B after internalization, establishing that RTK activation and inactivation are spatially and temporally partitioned within cells... 
Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatinGeorgia Xouri
Laboratory of General Biology, School of Medicine, University of Patras, Patras, Greece
EMBO J 26:1303-14. 2007..We propose that dynamic Cdt1-chromatin associations and the recruitment of Geminin to chromatin provide spatio-temporal control of the licensing process...