Jutta Veits

Summary

Country: Germany

Publications

  1. pmc Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryos
    Ahmed S Abdel-Moneim
    Virology Department, Faculty of Veterinary Medicine, Beni Suef University, Beni Suef, Egypt
    Virol J 6:15. 2009
  2. doi request reprint Protective efficacy of several vaccines against highly pathogenic H5N1 avian influenza virus under experimental conditions
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald Insel Riems, Germany
    Vaccine 26:1688-96. 2008
  3. pmc Highly pathogenic H5N1 influenza viruses carry virulence determinants beyond the polybasic hemagglutinin cleavage site
    Jessica Bogs
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    PLoS ONE 5:e11826. 2010
  4. ncbi request reprint The UL47 gene of avian infectious laryngotracheitis virus is not essential for in vitro replication but is relevant for virulence in chickens
    Dorothee Helferich
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    J Gen Virol 88:732-42. 2007
  5. ncbi request reprint Vaccination with Newcastle disease virus vectored vaccine protects chickens against highly pathogenic H7 avian influenza virus
    Diana Schröer
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, D 17493 Greifswald Insel Riems, Germany
    Avian Dis 53:190-7. 2009
  6. doi request reprint Level of protection of chickens against highly pathogenic H5 avian influenza virus with Newcastle disease virus based live attenuated vector vaccine depends on homology of H5 sequence between vaccine and challenge virus
    Angela Römer-Oberdörfer
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, D 17493 Greifswald Insel Riems, Germany
    Vaccine 26:2307-13. 2008
  7. pmc Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Boddenblick 5a, D 17493 Greifswald Insel Riems, Germany
    Proc Natl Acad Sci U S A 103:8197-202. 2006
  8. ncbi request reprint Identification of transcripts and protein products of the UL31, UL37, UL46, UL47, UL48, UL49 and US4 gene homologues of avian infectious laryngotracheitis virus
    Dorothee Helferich
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    J Gen Virol 88:719-31. 2007
  9. doi request reprint Protection of chickens against H5N1 highly pathogenic avian influenza virus infection by live vaccination with infectious laryngotracheitis virus recombinants expressing H5 hemagglutinin and N1 neuraminidase
    Sophia P Pavlova
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    Vaccine 27:773-85. 2009
  10. ncbi request reprint Identification and functional analysis of membrane proteins gD, gE, gI, and pUS9 of Infectious laryngotracheitis virus
    Sophia Pavlova
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, 17493 Greifswald Insel Riems, Germany
    Avian Dis 57:416-26. 2013

Collaborators

Detail Information

Publications31

  1. pmc Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryos
    Ahmed S Abdel-Moneim
    Virology Department, Faculty of Veterinary Medicine, Beni Suef University, Beni Suef, Egypt
    Virol J 6:15. 2009
    ..Aim of this study was to investigate by immunohistochemistry (IHC) the tissue tropism of avian infectious bronchitis virus (IBV) strain M41 in experimentally infected chicken embryos...
  2. doi request reprint Protective efficacy of several vaccines against highly pathogenic H5N1 avian influenza virus under experimental conditions
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald Insel Riems, Germany
    Vaccine 26:1688-96. 2008
    ....
  3. pmc Highly pathogenic H5N1 influenza viruses carry virulence determinants beyond the polybasic hemagglutinin cleavage site
    Jessica Bogs
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    PLoS ONE 5:e11826. 2010
    ..Moreover, besides the polybasic cleavage site, the additional virulence determinants of H5N1 HPAIV are located within the HA itself and in other viral proteins...
  4. ncbi request reprint The UL47 gene of avian infectious laryngotracheitis virus is not essential for in vitro replication but is relevant for virulence in chickens
    Dorothee Helferich
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    J Gen Virol 88:732-42. 2007
    ..As all immunized animals were protected against subsequent challenge infection with virulent ILTV, the UL47 deletion mutant might be suitable as a live-virus vaccine...
  5. ncbi request reprint Vaccination with Newcastle disease virus vectored vaccine protects chickens against highly pathogenic H7 avian influenza virus
    Diana Schröer
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, D 17493 Greifswald Insel Riems, Germany
    Avian Dis 53:190-7. 2009
    ..Furthermore, the immunized birds developed antibodies against the AIV nucleoprotein after challenge infection. Thus, NDVH7m could be used as a marker vaccine against subtype H7 avian influenza...
  6. doi request reprint Level of protection of chickens against highly pathogenic H5 avian influenza virus with Newcastle disease virus based live attenuated vector vaccine depends on homology of H5 sequence between vaccine and challenge virus
    Angela Römer-Oberdörfer
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, D 17493 Greifswald Insel Riems, Germany
    Vaccine 26:2307-13. 2008
    ..Our data thus show that application of a vector-based vaccine in the control of influenza may require adaptation of the vaccine to currently circulating viruses...
  7. pmc Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Boddenblick 5a, D 17493 Greifswald Insel Riems, Germany
    Proc Natl Acad Sci U S A 103:8197-202. 2006
    ..Therefore, recombinant NDVH5m is suitable as a bivalent vaccine against NDV and AIV and may be used as marker vaccine for the control of avian influenza...
  8. ncbi request reprint Identification of transcripts and protein products of the UL31, UL37, UL46, UL47, UL48, UL49 and US4 gene homologues of avian infectious laryngotracheitis virus
    Dorothee Helferich
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    J Gen Virol 88:719-31. 2007
    ..Taken together, these results indicate that the functions of all of the investigated ILTV proteins are related to those of their homologues in other alphaherpesviruses...
  9. doi request reprint Protection of chickens against H5N1 highly pathogenic avian influenza virus infection by live vaccination with infectious laryngotracheitis virus recombinants expressing H5 hemagglutinin and N1 neuraminidase
    Sophia P Pavlova
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    Vaccine 27:773-85. 2009
    ..Furthermore, chickens vaccinated with ILTV vectors can be easily differentiated from influenza virus-infected animals by the absence of serum antibodies against the AIV nucleoprotein...
  10. ncbi request reprint Identification and functional analysis of membrane proteins gD, gE, gI, and pUS9 of Infectious laryngotracheitis virus
    Sophia Pavlova
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, 17493 Greifswald Insel Riems, Germany
    Avian Dis 57:416-26. 2013
    ..Since homologous gene-deletion mutants of other alphaherpesviruses are in use as live vaccines, the generated ILTV recombinants might be also suitable for this application...
  11. pmc Avian influenza virus hemagglutinins H2, H4, H8, and H14 support a highly pathogenic phenotype
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, 17493 Greifswald Insel Riems, Germany
    Proc Natl Acad Sci U S A 109:2579-84. 2012
    ..Therefore, the restriction of natural HPAIV to serotypes H5 and H7 is likely a result of their unique predisposition for acquisition of a polybasic HA cleavage site...
  12. doi request reprint H9 avian influenza reassortant with engineered polybasic cleavage site displays a highly pathogenic phenotype in chicken
    Sandra Gohrbandt
    Friedrich Loeffler Institute, Institute of Molecular Biology, Greifswald Insel Riems, Germany
    J Gen Virol 92:1843-53. 2011
    ..23. These results suggest that an HPAIV with a subtype other than H5 or H7 would only emerge under conditions where the HA gene could acquire a polybasic cleavage site and the other viral genes carry additional virulence determinants...
  13. ncbi request reprint Efficacy of Newcastle disease virus recombinant expressing avian influenza virus H6 hemagglutinin against Newcastle disease and low pathogenic avian influenza in chickens and turkeys
    Diana Schröer
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, D 17493 Greifswald Insel Riems, Germany
    Avian Dis 55:201-11. 2011
    ..Therefore, the vector virus has to be improved to overcome these limitations...
  14. ncbi request reprint Live vaccination with an H5-hemagglutinin-expressing infectious laryngotracheitis virus recombinant protects chickens against different highly pathogenic avian influenza viruses of the H5 subtype
    Sophia P Pavlova
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    Vaccine 27:5085-90. 2009
    ..Vaccination with HA-expressing ILTV also allowed differentiation of immunized from AIV-infected animals by serological tests for antibodies against influenza virus nucleoprotein...
  15. ncbi request reprint Coexpression of avian influenza virus H5 and N1 by recombinant Newcastle disease virus and the impact on immune response in chickens
    Kristina Ramp
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, D 17493 Greifswald Insel Riems, Germany
    Avian Dis 55:413-21. 2011
    ..Furthermore, expression of AIV N1, in addition to AIV H5 by NDV, did not increase protection against HPAIV H5N1...
  16. pmc Chimeric newcastle disease virus protects chickens against avian influenza in the presence of maternally derived NDV immunity
    Constanze Steglich
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    PLoS ONE 8:e72530. 2013
    ..Thus, tailored NDV vector vaccines can be provided for use in the presence or absence of routine NDV vaccination. ..
  17. pmc Reversion of PB2-627E to -627K during replication of an H5N1 Clade 2.2 virus in mammalian hosts depends on the origin of the nucleoprotein
    Jessica Bogs
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald Insel Riems, Germany
    J Virol 85:10691-8. 2011
    ..However, the prompt reversion to PB2-627K in MDCK cells and mice suggests that the clade 2.2 H5N1 HPAIV may have had a history of intermediate mammalian hosts...
  18. ncbi request reprint Molecular biology of avian infectious laryngotracheitis virus
    Walter Fuchs
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Boddenblick 5a, 17493 Greifswald Insel Riems, Germany
    Vet Res 38:261-79. 2007
    ..Since they include immunogenic envelope glycoproteins, these results can contribute to the improvement of virus diagnostics, and to the development of marker vaccines...
  19. doi request reprint In vitro and in vivo characterization of glycoprotein C-deleted infectious laryngotracheitis virus
    Sophia P Pavlova
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    J Gen Virol 91:847-57. 2010
    ....
  20. doi request reprint Amino acids adjacent to the haemagglutinin cleavage site are relevant for virulence of avian influenza viruses of subtype H5
    Sandra Gohrbandt
    Friedrich Loeffler Institut, Institute of Molecular Biology, Greifswald Insel Riems, Germany
    J Gen Virol 92:51-9. 2011
    ..These data suggest that evolution of H5 HPAIVs from low-pathogenic precursors, besides acquisition of a polybasic cleavage site, involves adaptation of neighbouring regions...
  21. ncbi request reprint Enhancement of pathogenicity of Newcastle disease virus by alteration of specific amino acid residues in the surface glycoproteins F and HN
    Angela Römer-Oberdörfer
    Institute of Molecular Biology, Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    Avian Dis 50:259-63. 2006
    ..5. The HN mutation visibly altered conformation of the protein, resulting in the formation of disulfide-linked HN dimers that may indicate that this HN conformation is beneficial for the virulent phenotype...
  22. doi request reprint Identification and functional analysis of the small membrane-associated protein pUL11 of avian infectious laryngotracheitis virus
    Walter Fuchs
    Institute of Molecular Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    Virus Res 163:599-608. 2012
    ..The now available unique pUL11-specific mAb will help to further analyze this function, which is presumably mediated by physical interactions with other viral gene products, in cultured cells and in the natural animal host of ILTV...
  23. doi request reprint Genetic changes that accompanied shifts of low pathogenic avian influenza viruses toward higher pathogenicity in poultry
    El Sayed M Abdelwhab
    Friedrich Loeffler Institut, Greifswald Insel Riems, Germany
    Virulence 4:441-52. 2013
    ..Mutations that were found directly in those outbreaks are more likely to be linked to virulence, pathogenesis, and early adaptation of AIV...
  24. pmc In vitro and in vivo relevance of infectious laryngotracheitis virus gJ proteins that are expressed from spliced and nonspliced mRNAs
    Walter Fuchs
    Institute of Molecular Biology, Friedrich Loeffler Institut, Boddenblick 5a, 17493 Greifswald Insel Riems, Germany
    J Virol 79:705-16. 2005
    ..Thus, gJ deletion mutants of ILTV might be usable as attenuated live-virus vaccines. Furthermore, the gJ gene might constitute a reliable marker for serological discrimination between vaccinated and field virus-infected chickens...
  25. ncbi request reprint Contribution of the length of the HN protein and the sequence of the F protein cleavage site to Newcastle disease virus pathogenicity
    Angela Römer-Oberdörfer
    Institute of Molecular Biology, Friedrich Loeffler Institutes, Federal Research Centre for Virus Diseases of Animals, D 17493 Greifswald Insel Riems, Germany
    J Gen Virol 84:3121-9. 2003
    ..5 and suggests the involvement of additional virulence determinants that contribute to the pathogenicity of NDV...
  26. doi request reprint Protein display by bovine herpesvirus type 1 glycoprotein B
    Gunther M Keil
    Friedrich Loeffler Institut, Boddenblick 5a, 17493 Greifswald Insel Riems, Germany
    Vet Microbiol 143:29-36. 2010
    ..g. gene therapy applications especially when biologically active ligands need to be presented...
  27. pmc Acquisition of a polybasic hemagglutinin cleavage site by a low-pathogenic avian influenza virus is not sufficient for immediate transformation into a highly pathogenic strain
    Olga Stech
    Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Greifswald Insel Riems, Germany
    J Virol 83:5864-8. 2009
    ....
  28. ncbi request reprint [Recombinant viruses of poultry as vector vaccines against fowl plague]
    Walter Fuchs
    Institut fur Molekularbiologie, Friedrich Loeffler Institut, Bundesforschungsinstitut für Tiergesundheit, Greifswald Insel Riems
    Berl Munch Tierarztl Wochenschr 119:160-6. 2006
    ..An H5-expressing FPV recombinant is already in use in Central America and Southeast Asia but without accompanying marker diagnostics. Advantages and disadvantages of the different viral vectors are discussed...
  29. ncbi request reprint Isolation and characterization of monoclonal antibodies against structural proteins of infectious laryngotracheitis virus
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institutes, Federal Research Centre for Virus Diseases of Animals, Boddenblick 5a, D 17493 Greifswald Insel Riems, Germany
    Avian Dis 47:330-42. 2003
    ..The remaining ILTV-specific MAbs recognized viral proteins of 22 kD (group IV) and 38 kD (group V) that were not further characterized up to now...
  30. ncbi request reprint Five unique open reading frames of infectious laryngotracheitis virus are expressed during infection but are dispensable for virus replication in cell culture
    Jutta Veits
    Institute of Molecular Biology, Friedrich Loeffler Institutes, Federal Research Centre for Virus Diseases of Animals, D 17493 Greifswald Insel Riems, Germany
    J Gen Virol 84:1415-25. 2003
    ..These findings indicate that the ILTV-specific ORF A to ORF E genes might be important for virus replication in the natural host organism...
  31. ncbi request reprint Deletion of the non-essential UL0 gene of infectious laryngotracheitis (ILT) virus leads to attenuation in chickens, and UL0 mutants expressing influenza virus haemagglutinin (H7) protect against ILT and fowl plague
    Jutta Veits
    Institutes of Molecular Biology, Friedrich Loeffler Institutes, Federal Research Centre for Virus Diseases of Animals, D 17493 Greifswald Insel Riems, Germany
    J Gen Virol 84:3343-52. 2003
    ..Unlike inactivated influenza virus vaccines, HA-expressing ILTV recombinants should be suitable for mass application and would also permit serological discrimination between vaccinated and virus-infected animals in the field...