A Zittermann

..However, more controlled clinical trials are needed to investigate whether optimal oral vitamin D supplementation is able to reduce CVD morbidity and mortality...

..The data suggest that normal menstrual cycling in young women is associated with monthly fluctuations in bone turnover. This physiological effect of the menstrual cycle is most probably related to variations in serum E2 concentrations...

..High intake of soy products has been suggested to prevent breast cancer, osteoporosis, and cardiovascular diseases...

..The oral dose necessary to achieve adequate serum 25(OH)D levels is probably much higher than the current recommendations of 5-15 microg/d...

..This study was designed to evaluate the association between vitamin D status and congestive heart failure (CHF)...

..The acute effects of physical activity on intestinal calcium (Ca) uptake and on bone metabolism are not known...

..In contrast, therapy with very high pharmacological doses of the vitamin K2 menatetrenone has impressively been used to prevent further bone mineral loss and fracture risk in osteoporotic patients...

..Little is known about the onset and degree of biochemical and functional alterations in calcium metabolism during microgravity...

..There is evidence from animal studies that lactose has a beneficial effect on intestinal calcium absorption. However, data concerning the effect of lactose on calcium absorption in lactose-tolerant adults are inconclusive...

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..Distinct effects on estrogen-related diseases can be explained at least in part by the different affinity of isoflavones to estrogen receptors alpha and beta and the distinct tissue distribution of these receptors...

..Results are a further indication that monthly fluctuations of bone resorption in young women are mediated by sex hormones and that osteoclastic activity is stimulated by cytokines in vivo...

..To clarify the potential role of vitamin D supplementation on bone metabolism in congestive heart failure (CHF) patients with low vitamin D status and insufficient dietary calcium intake...

..CONCLUSIONS: Data indicate an uncoupling of bone formation and bone resorption in AN, which is primarily the result of a low BMI and influenced by the duration of the disease...

..These changes appear in association with the onset of a negative nitrogen balance, but decreased bone collagen synthesis and enhanced collagen breakdown occur after a time lag of several weeks...

..Variations in 25OHD levels are in line with the seasonal fluctuations in vitamin D status...

..However, the low serum levels of intact osteocalcin and the high ratio of undercarboxylated-to-intact osteocalcin deserve further consideration...

..We conclude that the low vitamin D status of infants born in winter may at least in part adversely affect biomarkers of allergy risk...

..Our data provide evidence for the involvement of an impaired vitamin D-parathyroid hormone axis in the progression of CHF...

..At present, daily oral intake of 50-100 microg vitamin D seems to be the most effective way to improve vitamin D status in CHF patients...

..As a consequence, legislation has to be changed to allow higher amounts of vitamin D in fortified foods and supplements...

..Preventive strategies are able to normalize bone metabolism and to attenuate the high bone loss during the first year after heart transplantation...

..63 years). In summary, the present data suggest that short-term treatment with atorvastatin may have age-dependent effects on biochemical markers of bone turnover in postmenopausal women...

..However, as an invasive procedure it is associated with a definite risk for complications. Therefore, it was examined whether changes in QT time and QT dispersion on the surface ECG are able to predict an acute cellular rejection...

..We assessed the value of deceleration time (dt) of diastolic wave of pulmonary venous flow (PVF) (PVF_dt) as noninvasive estimation of pulmonary wedge pressure (PWP) in candidates for and recipients of heart transplantation...

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..001). Our results demonstrate that CHF patients and controls differed in several vitamin D-associated lifestyle factors and in alcohol consumption during earlier periods of their lives...

..Vitamin D receptor knockout mice develop typical signs of congestive heart failure (CHF). In approximately 20% of stable CHF patients, frankly low concentrations of the vitamin D hormone calcitriol are found...

..Our data demonstrate that long-term survival is acceptable in heart transplant recipients with preoperatively diagnosed DM and DRCs. Consequently, advanced DM should no longer be a relative contraindication for heart transplantation...

..The effects of vitamin D excess and deficiency on vascular calcification are reviewed in this article...

..However, reliable data on mortality and its risk factors in octogenarians after replacement of aortic bioprostheses are limited...

..All newly developed procedures for the treatment of aortic stenosis therefore will have to prove their superiority in future...

..Reliable data on mortality and risk factors in octogenarians after replacement of aortic valve prostheses are scanty, however...

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..This study aimed to further evaluate the role of the Thr164Ile-beta(2)AR in CHF. For this we hypothesized that the Thr164Ile-beta(2)AR variant should be more abundant in HTX-patients than in patients with stable CHF or healthy controls...

..To determine whether genetic factors are involved in the development of renal dysfunction under immunosuppressive therapy, we screened various genes for sequence variations...