Zhike Zi

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. doi A tutorial on mathematical modeling of biological signaling pathways
    Zhike Zi
    bioss Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany
    Methods Mol Biol 880:41-51. 2012
  2. doi Sensitivity analysis approaches applied to systems biology models
    Z Zi
    University of Freiburg, bioss Centre for Biological Signalling Studies, Freiburg, Germany
    IET Syst Biol 5:336-6. 2011
  3. pmc A quantitative study of the Hog1 MAPK response to fluctuating osmotic stress in Saccharomyces cerevisiae
    Zhike Zi
    Centre for Biological Signalling Studies bioss, University of Freiburg, Freiburg, Germany
    PLoS ONE 5:e9522. 2010
  4. doi SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models
    Zhike Zi
    bioss Centre for Biological Signalling Studies, Center for Biological Systems Analysis ZBSA, University of Freiburg, Freiburg, Germany
    Bioinformatics 27:1028-9. 2011
  5. pmc Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics
    Zhike Zi
    BIOSS Centre for Biological Signalling Studies and Center for Biological Systems Analysis ZBSA, University of Freiburg, Freiburg, Germany
    Mol Syst Biol 7:492. 2011
  6. doi Dynamics of TGF-β/Smad signaling
    Zhike Zi
    bioss Centre for Biological Signalling Studies, University of Freiburg, Freiburg 79104, Germany
    FEBS Lett 586:1921-8. 2012

Detail Information

Publications6

  1. doi A tutorial on mathematical modeling of biological signaling pathways
    Zhike Zi
    bioss Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany
    Methods Mol Biol 880:41-51. 2012
    ..This chapter introduces how to use the bottom-up approach to establish mathematical models for cell signaling studies...
  2. doi Sensitivity analysis approaches applied to systems biology models
    Z Zi
    University of Freiburg, bioss Centre for Biological Signalling Studies, Freiburg, Germany
    IET Syst Biol 5:336-6. 2011
    ....
  3. pmc A quantitative study of the Hog1 MAPK response to fluctuating osmotic stress in Saccharomyces cerevisiae
    Zhike Zi
    Centre for Biological Signalling Studies bioss, University of Freiburg, Freiburg, Germany
    PLoS ONE 5:e9522. 2010
    ..The Hog1 mitogen-activated protein kinase (MAPK) pathway is crucial for the adaption of yeast cells to external osmotic changes...
  4. doi SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models
    Zhike Zi
    bioss Centre for Biological Signalling Studies, Center for Biological Systems Analysis ZBSA, University of Freiburg, Freiburg, Germany
    Bioinformatics 27:1028-9. 2011
    ..The tool is developed and parallelized using the message passing interface (MPI) protocol, which provides good scalability with the number of processors...
  5. pmc Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics
    Zhike Zi
    BIOSS Centre for Biological Signalling Studies and Center for Biological Systems Analysis ZBSA, University of Freiburg, Freiburg, Germany
    Mol Syst Biol 7:492. 2011
    ..Our results suggest that long-term switch-like signaling responses in the TGF-β pathway might be critical for cell fate determination...
  6. doi Dynamics of TGF-β/Smad signaling
    Zhike Zi
    bioss Centre for Biological Signalling Studies, University of Freiburg, Freiburg 79104, Germany
    FEBS Lett 586:1921-8. 2012
    ..These studies reveal many interesting dynamics of TGF-β signaling and how cells quantitatively decode variable doses of TGF-β stimulation...