Research Topics
Species | Hui ZhouSummaryAffiliation: University of Bonn Country: Germany Publications
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Detail Information
Publications
Carcinoma of the ampulla of Vater: comparative histologic/immunohistochemical classification and follow-upHui Zhou
Department of Pathology, University of Bonn, Bonn, Germany
Am J Surg Pathol 28:875-82. 2004..The overall survival was significantly shorter in males (P = 0.032) and patients with positive nodal stage (N1 < N0; P = 0.0025)...
Stem cell marker expression in small cell lung carcinoma and developing lung tissueLin Kristin Koch
Institut of Pathology, University of Bonn, Bonn, Germany
Hum Pathol 39:1597-605. 2008..Taken together, we show that small cell lung cancers and clustered epithelial cells in developing proximal bronchi share the expression of stem cell markers, suggesting a possible histogenetic link...- Pathogenesis of carcinoma of the papilla of VaterHans-Peter Fischer
Department of Pathology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany
J Hepatobiliary Pancreat Surg 11:301-9. 2004..Consequently, the histologic classification should reflect the histogenesis of ampullary tumors from the two different types of papillary mucosa... - Gene expression profiling identifies new biological markers of neoplastic germ cellsKatharina Biermann
Institute of Pathology, University Hospital Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany
Anticancer Res 27:3091-100. 2007..There is only limited knowledge about gene expression in human testicular germ cell tumors of adolescents and adults (TGCTs), and, in particular in its preinvasive stage intratubular germ cell neoplasia unclassified (IGCNU)... - Gonadoblastoma: evidence for a stepwise progression to dysgerminoma in a dysgenetic ovaryKatharina Pauls
Institute of Pathology, University of Bonn, Bonn, Germany
Virchows Arch 447:603-9. 2005..Our results show that gonadoblastomas mimic female fetal ovary and exhibit a stepwise progression from follicular pattern to coronary pattern and finally to dysgerminomas... - Genome-wide expression profiling reveals new insights into pathogenesis and progression of testicular germ cell tumorsKatharina Biermann
Department of Pathology, University of Bonn, Bonn, Germany
Cancer Genomics Proteomics 4:359-67. 2007..In summary, our data identified tumor type-specific gene signatures of GCT and provided new insights into genetic pathways driving the transition to seminomas and embryonal carcinomas from their respective precursor lesions... - Spatial expression of germ cell markers during maturation of human fetal male gonads: an immunohistochemical studyKatharina Pauls
Institute of Pathology and Department of Developmental Pathology, University of Bonn, Germany
Hum Reprod 21:397-404. 2006..The aim of the present study was to examine fetal male germ cells for expression of proteins associated with differentiation and maturation and to compare them with morphologically defined subpopulations... - Acute adenoviral infection of a graft by serotype 35 following renal transplantationNicolaus Friedrichs
Institute of Pathology, University of Bonn, Bonn, Germany
Pathol Res Pract 199:565-70. 2003..Our case highlights the importance of applying all possible diagnostic techniques, including histological evaluation of renal biopsies... - Uterine tumor resembling an ovarian sex cord tumor associated with metastasisKatharina Biermann
Department of Pathology, University of Bonn, Bonn, Germany
Int J Gynecol Pathol 27:58-60. 2008..This case indicates that although the majority of UTROSCT are benign tumors, some of them might undergo malignant transformation and have a metastatic potency... - Primary peripancreatic lymph node gastrinoma in a woman with MEN1Hui Zhou
Department of Pathology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany
J Hepatobiliary Pancreat Surg 13:477-81. 2006..To our knowledge, this is the only well-documented case of a primary lymph node gastrinoma in a patient with MEN1. Our case supports the idea that any gastrinoma in patients with MEN1 should be surgically resected for cure if possible... - c-KIT codon 816 mutation in a recurrent and metastatic dysgerminoma of a 14-year-old girl: case studyKatharina Pauls
Department of Pathology, University of Bonn, Germany
Virchows Arch 445:651-4. 2004..Our case raises the question of whether exon 17 c-KIT mutations might be involved in the pathogenesis of dysgerminoma and whether exon 17 KIT mutations may predict aggressive and chemotherapy-resistant behavior of dysgerminomas... - Podocalyxin-like protein 1 expression is useful to differentiate pancreatic ductal adenocarcinomas from adenocarcinomas of the biliary and gastrointestinal tractsJasmin Teresa Ney
Institute of Pathology, University of Bonn, Bonn, Germany
Hum Pathol 38:359-64. 2007..Adenocarcinomas of the lung and prostate, and liver metastases of colorectal carcinomas lacked PODXL-1 expression. It is concluded that immunoreactivity for PODXL-1 favors a pancreatic origin if ampullary carcinoma is excluded... - Primitive neuroectodermal tumor (PNET) in the differential diagnosis of malignant kidney tumorsNicolaus Friedrichs
Department of Pathology, Universitiy of Bonn, Germany
Pathol Res Pract 198:563-9. 2002..Eighteen months after therapy, the patient is in excellent health condition without any evidence of tumor recurrence... - Plasma cell granuloma of the thyroid gland mimicking carcinoma: a case report and review of the literatureLydia Kriegl
Institute of Pathology, Ludwig Maximilians University of Munich, Germany
Pathol Res Pract 203:813-7. 2007..This is the first case in which molecular pathological analyses for EBV and HHV8 DNA were made. As these were negative, distinct etiological features were suggested... - Glycosylphosphatidylinositol (GPI) anchor is required in Aspergillus fumigatus for morphogenesis and virulenceHong Li
State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, and The General Hospital of Chinese People s Armed Police Forces, Beijing 100080, China
Mol Microbiol 64:1014-27. 2007..In vivo assays revealed that the mutant exhibited a reduced virulence in immunocompromised mice. The GPI anchor was not essential for viability, but required for the cell wall integrity, morphogenesis and virulence in A. fumigatus... 
O-Mannosyltransferase 1 in Aspergillus fumigatus (AfPmt1p) is crucial for cell wall integrity and conidium morphology, especially at an elevated temperatureHui Zhou
State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
Eukaryot Cell 6:2260-8. 2007..In a mouse model, Afpmt1 was not required for the virulence of A. fumigatus under the experimental conditions used...- Salivary proteomic and genomic biomarkers for primary Sjögren's syndromeShen Hu
University of California, Los Angeles, California, USA
Arthritis Rheum 56:3588-600. 2007..To identify a panel of protein and messenger RNA (mRNA) biomarkers in human whole saliva (WS) that may be used in the detection of primary Sjögren's syndrome (SS)... - Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independentlyJen Zen Chuang
Department of Ophthalmology, Weill Medical College of Cornell University, New York, New York 10012, USA
J Biol Chem 277:19831-8. 2002..Collectively, these results suggest that MRJ has a relevant functional role in neurons... - Oxidative stress, defense response, and early biomarkers for lead-contaminated soil in Vicia faba seedlingsCheng Run Wang
State Key Laboratory of Pollution Control and Resources Reuse, School of Environment, Nanjing University, Nanjing 210093, China
Environ Toxicol Chem 27:970-7. 2008..The results showed that O*(2)(-), hsp 70, and guaiacol peroxidase isoenzymes had the most sensitive responses in the seedlings and these parameters could be potential early biomarkers of soil Pb contamination... - Exon-level expression profiling: a comprehensive transcriptome analysis of oral fluidsZhanzhi Hu
Dental Research Institute, 73 017 Center for Health Sciences, University of California, Los Angeles, CA 90095 1668, USA
Clin Chem 54:824-32. 2008..The aim of this study was to provide proof-of-concept data on the combination of a universal mRNA-amplification method with exon arrays for candidate selection and a multiplex preamplification method for easy validation... - Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtinChuan En Wang
Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA
J Cell Biol 181:803-16. 2008.... - Deletion of the msdS/AfmsdC gene induces abnormal polarity and septation in Aspergillus fumigatusYanjie Li
State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China
Microbiology 154:1960-72. 2008..Although the mechanism by which the N-glycan processing affects polarity and septation is unclear, our results show that msdS is involved in polarity and septation in A. fumigatus... - snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genomeJian-Hua Yang
Key Laboratory of Gene Engineering of the Ministry of Education, Zhongshan University, Guangzhou 510275, PR China
Nucleic Acids Res 34:5112-23. 2006..The results of this study provide the most comprehensive listing of two families of snoRNA genes in the human genome till date... - Rice embryogenic calli express a unique set of microRNAs, suggesting regulatory roles of microRNAs in plant post-embryogenic developmentYu-Chun Luo
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, PR China
FEBS Lett 580:5111-6. 2006..By exploiting the correlations between the differential expression patterns of these miRNAs and their targets, the regulatory roles of the miRNAs on meristem maintenance and embryogenesis were indicated... - G(1)-phase specific apoptosis in liver carcinoma cell line induced by copper-1,10-phenanthrolineHui Zhou
College of Life Sciences, Wuhan University, 430072, Wuhan, PR China
Int J Biochem Cell Biol 34:678-84. 2002..Apoptosis induced by IICu(OP)(2) was limited to G(1)-phase cells. Using cyclin analysis, the expression of cyclin E in G(1) was blocked. Thus, it was concluded that IICu(OP)(2) can induce G(1)-phase specific apoptosis in Bel-7402... - Mislocalization of eNOS and upregulation of cerebral vascular Ca2+ channel activity in angiotensin-hypertensionVolodymyr Gerzanich
Department of Neurosurgery, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201-1595, USA
Hypertension 41:1124-30. 2003..These data provide the first evidence linking Ang-induced eNOS mislocalization, eNOS dysfunction, and Ca2+ channel upregulation, and they provide novel mechanistic insights into pathological changes in LSAs associated with stroke... - The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativaChun-Long Chen
Key Laboratory of Gene Engineering of the Ministry of Education, Biotechnology Research Center, Zhoushan University, Guangzhou 510275, China
Nucleic Acids Res 31:2601-13. 2003..Thus, the large snoRNA gene family in plants can serve as an excellent model for a rapid and functional evolution... - Trans-cellular proliferating cell nuclear antigen gene activation in cerebral vascular smooth muscle by endothelial oxidative injury in vivoVolodymyr Gerzanich
Department of Neurosurgery, University of Maryland School of Medicine, 22 South Greene St, Baltimore, MD 21201 1595, USA
Arterioscler Thromb Vasc Biol 23:2048-54. 2003..This study was undertaken to assess the role of vascular smooth muscle cell (VSMC) Ca2+ channels and Ca2+/calmodulin-dependent protein kinase II (CaMKII) in gene regulation after oxidative endothelial injury (OEI)... - Alternative splicing of cGMP-dependent protein kinase I in angiotensin-hypertension: novel mechanism for nitrate tolerance in vascular smooth muscleVolodymyr Gerzanich
Department of Neurosurgery, University of Maryland at Baltimore, Baltimore, MD, USA
Circ Res 93:805-12. 2003..Our data identify a functional role for cGKIbeta in VSMCs previously ascribed exclusively to cGKIalpha. Ang-induced alternative splicing of cGKI represents a novel mechanism for reducing sensitivity to NO/cGMP... - [Effect of ornidazole on sperm in rats and its mechanism of action]Xue Bing Pang
Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
Zhonghua Nan Ke Xue 11:26-8. 2005..To explore the reductive effect of ornidazole on sperm motility in rats and its mechanism of action... - Identification and functional analysis of 20 Box H/ACA small nucleolar RNAs (snoRNAs) from Schizosaccharomyces pombeSi-Guang Li
Key Laboratory of Gene Engineering of the Ministry of Education, Biotechnology Research Center, Zhongshan University, Guangzhou 510275, China
J Biol Chem 280:16446-55. 2005..pombe snoRNAs, with their functional homologues in diverse organisms, suggests a mechanism by which the snoRNAs have evolved in coordination with rRNAs to preserve the post-transcriptional modification sites among distant eukaryotes... - Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAsZhan-Peng Huang
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, Zhongshan University, Guangzhou 510275, Republic of China
RNA 11:1303-16. 2005..These results demonstrate the extensive utilization of introns for coding of snoRNAs in the host genes and shed light on further research of other noncoding RNA genes in the large introns of the Drosophila genome... - High diversity of endophytic fungi from the pharmaceutical plant, Heterosmilax japonica Kunth revealed by cultivation-independent approachXiao-Xia Gao
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, PR China
FEMS Microbiol Lett 249:255-66. 2005..Furthermore, our result also showed that the samples collected in spring harbored more abundant endophytic populations than that in summer, implying a seasonal fluctuation for the endophytes in H. japonica... - [Effect of yiqijiedu granule on the implanted-tumor protein expression in nasopharyngeal carcinoma]Fa qing Tang
Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha 410008
Zhong Nan Da Xue Xue Bao Yi Xue Ban 29:577-82. 2004..To investigate the inhibitory mechanism of Yiqijiedu granule on the implanted-tumor growth of nasopharyngeal carcinoma in nude mice... - Differential immunoscreening identifies a glycosylation variant of the epidermal growth factor receptor in ME-180 cervical carcinoma cellsYi Te Hsu
Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA
Hybridoma (Larchmt) 24:225-30. 2005..Overall, our study suggests that the differentially glycosylated EGF receptor could potentially serve as a unique target for the immunotherapeutic treatment of cervical cancer... - [Impact of cytochrome P450 CYP2C9 variant allele CYP2C9 * 3 on the pharmacokinetics of glibenclamide and lornoxicam in Chinese subjects]Yi fan Zhang
Laboratory of Drug Metabolism and Pharmacokinetics, Shenyang Pharmaceutical University, Shenyang 110016, China
Yao Xue Xue Bao 40:796-9. 2005..To investigate the impact of CYP2C9 * 3 on the pharmacokinetics of glibenclamide and lornoxicam... - The SNPlex genotyping system: a flexible and scalable platform for SNP genotypingAndreas R Tobler
Applied Biosystems, Foster City, CA 94404, USA
J Biomol Tech 16:398-406. 2005..The SNPlex Genotyping System is an efficient and reliable tool for a broad range of genotyping applications, supported by applications for study design, data analysis, and data management... - The expression and significance of CATSPER1 in human testis and ejaculated spermatozoaHong Gang Li
Centre of Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Asian J Androl 8:301-6. 2006..The influence of anti-human CATSPER1 antibody upon human sperm motility was used to evaluate the function of human CATSPER1 and to estimate its possible use as a target for immunocontraception... - GDP-mannose pyrophosphorylase is essential for cell wall integrity, morphogenesis and viability of Aspergillus fumigatusHechun Jiang
State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China
Microbiology 154:2730-9. 2008..Our results showed that the Afsrb1 gene is essential for cell wall integrity, morphogenesis and viability of Aspergillus fumigatus...