O Wolkenhauer

Summary

Affiliation: University of Rostock
Country: Germany

Publications

  1. ncbi SysBioMed report: advancing systems biology for medical applications
    O Wolkenhauer
    University of Rostock, Rostock, Germany
    IET Syst Biol 3:131-6. 2009
  2. ncbi Family tree of Markov models in systems biology
    M Ullah
    Systems Biology and Bioinformatics Group, University of Rostock, A Einstein Str 21, 18051 Rostock, Germany
    IET Syst Biol 1:247-54. 2007
  3. ncbi Deterministic modelling and stochastic simulation of biochemical pathways using MATLAB
    M Ullah
    Systems Biology and Bioinformatics Group, University of Rostock, Albert Einstein Street 21, Rostock 18055, Germany
    Syst Biol (Stevenage) 153:53-60. 2006
  4. ncbi Mathematical modelling unravels regulatory mechanisms of interferon-γ-induced STAT1 serine-phosphorylation and MUC4 expression in pancreatic cancer cells
    C Kossow
    Department of Systems Biology and Bioinformatics, University of Rostock, 18051 Rostock, Germany
    IET Syst Biol 6:73-85. 2012
  5. ncbi A systems- and signal-oriented approach to intracellular dynamics
    O Wolkenhauer
    Systems Biology and Bioinformatics Group, Department of Computer Science, University of Rostock, Albert Einstein Strasse 21, 18059 Rostock, Germany
    Biochem Soc Trans 33:507-15. 2005
  6. ncbi Defining systems biology: an engineering perspective
    O Wolkenhauer
    University of Rostock, Germany
    IET Syst Biol 1:204-6. 2007
  7. ncbi Model-based investigation of the transcriptional activity of p53 and its feedback loop regulation via 14-3-3σ
    J Vera
    Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
    IET Syst Biol 5:293-307. 2011

Collaborators

  • N Le Novère
  • H Herzel
  • M Ullah
  • C Kossow
  • J Vera
  • K Rateitschak
  • D Jose
  • R Jaster
  • X Lai
  • A Singh
  • S Nikolov
  • H Schmidt
  • K H Cho

Detail Information

Publications7

  1. ncbi SysBioMed report: advancing systems biology for medical applications
    O Wolkenhauer
    University of Rostock, Rostock, Germany
    IET Syst Biol 3:131-6. 2009
    ..6. The hesitant stance of the pharmaceutical industry towards major investment in systems biology research has to be addressed. 7. Leading medical journals should be encouraged to promote mathematical modelling...
  2. ncbi Family tree of Markov models in systems biology
    M Ullah
    Systems Biology and Bioinformatics Group, University of Rostock, A Einstein Str 21, 18051 Rostock, Germany
    IET Syst Biol 1:247-54. 2007
    ..As a result, a 'family tree' for stochastic models in systems biology is sketched, providing explicit derivations of their formal relationship and clarifying assumptions involved...
  3. ncbi Deterministic modelling and stochastic simulation of biochemical pathways using MATLAB
    M Ullah
    Systems Biology and Bioinformatics Group, University of Rostock, Albert Einstein Street 21, Rostock 18055, Germany
    Syst Biol (Stevenage) 153:53-60. 2006
    ..The aim is to provide a concise set of MATLAB functions that encourage the experimentation with systems biology models. All the script files are available from www.sbi.uni-rostock.de/ publications_matlab-paper.html...
  4. ncbi Mathematical modelling unravels regulatory mechanisms of interferon-γ-induced STAT1 serine-phosphorylation and MUC4 expression in pancreatic cancer cells
    C Kossow
    Department of Systems Biology and Bioinformatics, University of Rostock, 18051 Rostock, Germany
    IET Syst Biol 6:73-85. 2012
    ..In addition, our results propose that unphosphorylated or serine-phosphorylated STAT1 can act as transcription factors of MUC4, either alone by progressive binding to different sites in the promoter or both together...
  5. ncbi A systems- and signal-oriented approach to intracellular dynamics
    O Wolkenhauer
    Systems Biology and Bioinformatics Group, Department of Computer Science, University of Rostock, Albert Einstein Strasse 21, 18059 Rostock, Germany
    Biochem Soc Trans 33:507-15. 2005
    ..Using tools of control systems analysis, as embodied in the disciplines of systems biology, similar predictive modelling/simulation studies are now bearing fruit in cell signalling research...
  6. ncbi Defining systems biology: an engineering perspective
    O Wolkenhauer
    University of Rostock, Germany
    IET Syst Biol 1:204-6. 2007
  7. ncbi Model-based investigation of the transcriptional activity of p53 and its feedback loop regulation via 14-3-3σ
    J Vera
    Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
    IET Syst Biol 5:293-307. 2011
    ..Moreover, the interplay between DNA damage and 14-3-3σ may induce bistability in the oscillation of p53...