Jochen Wohrle

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. ncbi request reprint PFO closuRE and CryptogenIc StrokE (PRECISE) registry: a multi-center, international registry
    Jochen Wohrle
    Department of Internal Medicine II, Cardiology, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Clin Res Cardiol 101:787-93. 2012
  2. doi request reprint Impact of cell number and microvascular obstruction in patients with bone-marrow derived cell therapy: final results from the randomized, double-blind, placebo controlled intracoronary Stem Cell therapy in patients with Acute Myocardial Infarction (SCAMI)
    Jochen Wohrle
    Clinic for Internal Medicine II, University of Ulm, Ulm, Germany
    Clin Res Cardiol 102:765-70. 2013
  3. doi request reprint Impact of bivalirudin and paclitaxel-eluting stents on outcomes in patients undergoing primary percutaneous coronary intervention of the left anterior descending artery
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Am J Cardiol 112:753-60. 2013
  4. doi request reprint Paclitaxel-coated balloon with bare-metal stenting in patients with chronic total occlusions in native coronary arteries
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Catheter Cardiovasc Interv 81:793-9. 2013
  5. doi request reprint SeQuentPlease World Wide Registry: clinical results of SeQuent please paclitaxel-coated balloon angioplasty in a large-scale, prospective registry study
    Jochen Wohrle
    Department of Internal Medicine II Cardiology, University of Ulm, Ulm, Germany
    J Am Coll Cardiol 60:1733-8. 2012
  6. ncbi request reprint Drug-coated balloons for coronary and peripheral interventional procedures
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Curr Cardiol Rep 14:635-41. 2012
  7. ncbi request reprint Effect of bivalirudin compared with unfractionated heparin plus abciximab on infarct size and myocardial recovery after primary percutaneous coronary intervention: the horizons-AMI CMRI substudy
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Ulm, Germany
    Catheter Cardiovasc Interv 79:1083-9. 2012
  8. doi request reprint Prevalence of myocardial scar in patients with cryptogenic cerebral ischemic events and patent foramen ovale
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Ulm, Germany
    JACC Cardiovasc Imaging 3:833-9. 2010
  9. doi request reprint Carbon-coated stents in patients with acute coronary syndromes
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Clin Cardiol 32:E1-6. 2009
  10. doi request reprint Impact of percutaneous device implantation for closure of patent foramen ovale on valve insufficiencies
    Jochen Wohrle
    Department of Internal Medicine II Cardiology, University of Ulm, Albert Einstein Allee 23, Ulm 89081, Germany
    Circulation 119:3002-8. 2009

Detail Information

Publications44

  1. ncbi request reprint PFO closuRE and CryptogenIc StrokE (PRECISE) registry: a multi-center, international registry
    Jochen Wohrle
    Department of Internal Medicine II, Cardiology, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Clin Res Cardiol 101:787-93. 2012
    ..The primary objective of the study was to determine the degree of risk for stroke or transient ischemic attack (TIA) in patients after Premere™ PFO closure device implantation...
  2. doi request reprint Impact of cell number and microvascular obstruction in patients with bone-marrow derived cell therapy: final results from the randomized, double-blind, placebo controlled intracoronary Stem Cell therapy in patients with Acute Myocardial Infarction (SCAMI)
    Jochen Wohrle
    Clinic for Internal Medicine II, University of Ulm, Ulm, Germany
    Clin Res Cardiol 102:765-70. 2013
    ....
  3. doi request reprint Impact of bivalirudin and paclitaxel-eluting stents on outcomes in patients undergoing primary percutaneous coronary intervention of the left anterior descending artery
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Am J Cardiol 112:753-60. 2013
    ..PES reduced revascularization rates in this population but did not have a significant impact on mortality...
  4. doi request reprint Paclitaxel-coated balloon with bare-metal stenting in patients with chronic total occlusions in native coronary arteries
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Catheter Cardiovasc Interv 81:793-9. 2013
    ..We sought to evaluate the efficacy and safety of paclitaxel-coated balloon plus bare-metal stenting (BMS) in chronic total occlusions (CTOs)...
  5. doi request reprint SeQuentPlease World Wide Registry: clinical results of SeQuent please paclitaxel-coated balloon angioplasty in a large-scale, prospective registry study
    Jochen Wohrle
    Department of Internal Medicine II Cardiology, University of Ulm, Ulm, Germany
    J Am Coll Cardiol 60:1733-8. 2012
    ..This study sought to assess the safety and efficacy of paclitaxel-coated balloon (PCB) angioplasty in an international, multicenter, prospective, large-scale registry study...
  6. ncbi request reprint Drug-coated balloons for coronary and peripheral interventional procedures
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Curr Cardiol Rep 14:635-41. 2012
    ..Registries indicate PCB to also be effective in lesions below the knee. Since there is no certain class effect, efficacy and safety have to be demonstrated for different types of PCB for coronary and peripheral interventions...
  7. ncbi request reprint Effect of bivalirudin compared with unfractionated heparin plus abciximab on infarct size and myocardial recovery after primary percutaneous coronary intervention: the horizons-AMI CMRI substudy
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Ulm, Germany
    Catheter Cardiovasc Interv 79:1083-9. 2012
    ..Whether a possible reduction in infarct size with bivalirudin may have contributed to the enhanced survival with this agent is unknown...
  8. doi request reprint Prevalence of myocardial scar in patients with cryptogenic cerebral ischemic events and patent foramen ovale
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Ulm, Germany
    JACC Cardiovasc Imaging 3:833-9. 2010
    ..This study sought to evaluate the prevalence of subclinical myocardial infarctions with cardiovascular magnetic resonance imaging (CMRI) in patients with patent foramen ovale (PFO) after cryptogenic cerebral ischemic events...
  9. doi request reprint Carbon-coated stents in patients with acute coronary syndromes
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Clin Cardiol 32:E1-6. 2009
    ..We evaluated angiographic and clinical results of non-drug-eluting carbon-coated stents...
  10. doi request reprint Impact of percutaneous device implantation for closure of patent foramen ovale on valve insufficiencies
    Jochen Wohrle
    Department of Internal Medicine II Cardiology, University of Ulm, Albert Einstein Allee 23, Ulm 89081, Germany
    Circulation 119:3002-8. 2009
    ..We studied the acute and long-term impact of percutaneous device implantation for PFO closure on valve insufficiencies in cardiac magnetic resonance imaging...
  11. pmc Angiographic results of the cobalt chromium Vision and Mini-Vision stents
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Can J Cardiol 25:581-4. 2009
    ..In the Basel Stent Kosten Effektivitats Trial (BASKET), target vessel revascularization after six months was nonsignificantly different between DES and BMS with clinical follow-up...
  12. doi request reprint Results of intracoronary stem cell therapy after acute myocardial infarction
    Jochen Wohrle
    University of Ulm, Clinic for Internal Medicine II, Ulm, Germany
    Am J Cardiol 105:804-12. 2010
    ....
  13. doi request reprint Impact of transfer for primary percutaneous coronary intervention on survival and clinical outcomes (from the HORIZONS-AMI Trial)
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Germany
    Am J Cardiol 106:1218-24. 2010
    ..In conclusion, in the HORIZONS-AMI trial, 30-day and 1-year survival rates and clinical outcomes were comparable in patients with STEMI requiring and not requiring transfer for primary PCI...
  14. doi request reprint Prospective randomised trial evaluating a paclitaxel-coated balloon in patients treated with endothelial progenitor cell capturing stents for de novo coronary artery disease
    Jochen Wohrle
    Clinic of Internal Medicine II, University of Ulm, Germany
    Heart 97:1338-42. 2011
    ..Percutaneous coronary intervention with stent implantation is limited by the occurrence of re-stenosis and the risk of stent thromboses...
  15. doi request reprint Everolimus-eluting stents for treatment of chronic total coronary occlusions
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Clin Res Cardiol 101:23-8. 2012
    ..We sought to determine the antiproliferative impact of the everolimus-eluting Xience V stent in CTOs...
  16. doi request reprint Impact of pioglitazone on coronary endothelial function in non-diabetic patients with coronary artery disease
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Clin Res Cardiol 97:726-33. 2008
    ..We studied the hypothesis that pioglitazone improves coronary endothelial dysfunction in non-diabetic patients with coronary artery disease (CAD) in a randomized, placebo-controlled, double-blind trial...
  17. ncbi request reprint Patients with in-stent restenoses: comparison of intracoronary beta-brachytherapy using a rhenium-188 filled balloon catheter with the polymer-based paclitaxel-eluting taxus-express stent
    J Wohrle
    Department of Internal Medicine II, University of Ulm, Robert Koch Str 8, 89081 Ulm, Germany
    Nuklearmedizin 46:185-91. 2007
    ..We compared the intracoronary beta-brachytherapy using a liquid rhenium-188 filled balloon with the slow-release, polymer-based, paclitaxel-eluting Taxus-Express stent for treatment of in-stent restenoses...
  18. ncbi request reprint Repeat intracoronary beta-brachytherapy using a rhenium-188-filled balloon catheter for recurrent restenosis in patients who failed intracoronary radiation therapy
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, 89081 Ulm, Germany
    Cardiovasc Revasc Med 7:2-6. 2006
    ..We report clinical and angiographic data regarding the safety and efficacy of rhenium-188 brachytherapy in restenoses after brachytherapy failure...
  19. ncbi request reprint Intracoronary beta-brachytherapy using a rhenium-188 filled balloon catheter in restenotic lesions of native coronary arteries and venous bypass grafts
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Eur J Nucl Med Mol Imaging 33:1314-20. 2006
    ..Against this background, we wanted to assess the impact of intracoronary beta-brachytherapy using a liquid (188)Re-filled balloon in restenotic lesions in native coronary arteries and venous bypass grafts...
  20. ncbi request reprint Closure of patent foramen ovale after cryptogenic stroke
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, 89081 Ulm, Germany
    Lancet 368:350-2. 2006
  21. ncbi request reprint Myocardial perfusion reserve in cardiovascular magnetic resonance: Correlation to coronary microvascular dysfunction
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    J Cardiovasc Magn Reson 8:781-7. 2006
    ..CMR combined with adenosine could be proposed as a non-invasive tool to evaluate CMD...
  22. ncbi request reprint [Stent thrombosis in the era of drug-eluting stents]
    Jochen Wohrle
    Klinik fur Innere Medizin II, Universitatsklinikum Ulm, Ulm
    Herz 32:411-8. 2007
    ..In complex lesions combined antiplatelet treatment should be prescribed 24 months or longer (e.g., DES after brachytherapy). Patients scheduled for surgical procedures or patients with reduced compliance should not be treated with DES...
  23. ncbi request reprint Comparison of the slow-release polymer-based paclitaxel-eluting Taxus-Express stent with the bare-metal Express stent for saphenous vein graft interventions
    J Wohrle
    Department of Internal Medicine II, University of Ulm, Germany
    Clin Res Cardiol 96:70-6. 2007
    ..Furthermore, a meta-analysis was performed regarding use of drug-eluting (DES) vs bare-metal stents (BMS) in SVG lesions...
  24. ncbi request reprint Cardiac magnetic resonance imaging and transesophageal echocardiography in patients with transcatheter closure of patent foramen ovale
    Thorsten Nusser
    Department of Internal Medicine II Cardiology, University of Ulm, Ulm, Germany
    J Am Coll Cardiol 48:322-9. 2006
    ..We studied the value of cardiac magnetic resonance imaging (CMRI) before and after closure of patent foramen ovale (PFO) in patients with cryptogenic ischemic events...
  25. ncbi request reprint Pioglitazone reduces neointima volume after coronary stent implantation: a randomized, placebo-controlled, double-blind trial in nondiabetic patients
    Nikolaus Marx
    Department of Internal Medicine II, Cardiology, University of Ulm, Ulm, Germany
    Circulation 112:2792-8. 2005
    ..In a randomized, placebo-controlled, double-blind trial, we examined the effect of 6-month pioglitazone therapy on neointima volume after coronary stenting in nondiabetic coronary artery disease patients...
  26. ncbi request reprint Intracoronary beta-irradiation with a rhenium-188-filled balloon catheter: a randomized trial in patients with de novo and restenotic lesions
    Martin Hoher
    Department of Internal Medicine II, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Circulation 107:3022-7. 2003
    ..Intracoronary irradiation reduces neointimal proliferation. We studied the efficacy of a self-centering liquid rhenium-188-filled balloon catheter for coronary beta-brachytherapy...
  27. doi request reprint Is contrast-enhanced cardiac magnetic resonance imaging at 3 T superior to 1.5 T for detection of coronary artery disease?
    Thomas Walcher
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081, Ulm, Germany
    Int J Cardiovasc Imaging 29:355-61. 2013
    ..3 vs. 88.9 %). This study showed that CMR at 3 T in a routine clinical setting is superior to 1.5 T in detection of significant CAD. 3 T might become the preferred CMR field strength for evaluation of CAD in clinical practice...
  28. ncbi request reprint Reduction of major adverse cardiac events with intracoronary compared with intravenous bolus application of abciximab in patients with acute myocardial infarction or unstable angina undergoing coronary angioplasty
    Jochen Wohrle
    Internal Medicine II, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Circulation 107:1840-3. 2003
    ..We studied whether intracoronary bolus administration of abciximab is associated with a reduced MACE rate compared with the standard intravenous bolus application...
  29. ncbi request reprint Diagnostic performance of magnetic resonance first pass perfusion imaging is equally potent in female compared to male patients with coronary artery disease
    Nico Merkle
    Clinic of Internal Medicine II Cardiology, University Hospital of Ulm, Albert Einstein Allee 23, 89081, Ulm, Germany
    Clin Res Cardiol 99:21-8. 2010
    ..Therefore, we tested the diagnostic power of cardiac magnetic resonance first pass perfusion imaging (CMR-FPPI) for the diagnosis of significant coronary stenoses in females versus males...
  30. pmc Assessment of myocardial perfusion for detection of coronary artery stenoses by steady-state, free-precession magnetic resonance first-pass imaging
    Nico Merkle
    Department of Internal Medicine II, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Heart 93:1381-5. 2007
    ..To evaluate the diagnostic impact of magnetic resonance imaging (MRI) first-pass perfusion using steady-state, free-precession (SSFP) sequences with parallel imaging (SENSE) for detection of coronary stenoses...
  31. ncbi request reprint No effect of highly dosed nitric oxide donor molsidomine on the angiographic restenosis rate after percutaneous coronary angioplasty: a randomized, placebo controlled, double-blind trial
    Jochen Wohrle
    Department of Cardiology, University of Ulm, Ulm, Germany
    Can J Cardiol 19:495-500. 2003
    ..Because these effects are mainly dose dependent, NO-releasing drugs have to be applied at a high dose to have an effect on restenotic mechanisms...
  32. doi request reprint Angiographic validation of magnetic resonance assessment of myocardium at risk in non-ST-elevation myocardial infarction
    Dominik Buckert
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081, Ulm, Germany
    Int J Cardiovasc Imaging 29:1295-301. 2013
    ..6 %). There is a good correlation between the AAR assessed by CMR and by angiography (r = 0.65, p < 0.001). T2-weigthed CMR is able to quantify the AAR with very good correlation to the angiographic APPROACH-score in NSTEMI patients...
  33. ncbi request reprint Myocardial perfusion reserve assessed by T2-prepared steady-state free precession blood oxygen level-dependent magnetic resonance imaging in comparison to fractional flow reserve
    Thomas Walcher
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 2, Ulm, Germany
    Circ Cardiovasc Imaging 5:580-6. 2012
    ..The aim of our study was to analyze the potential diagnostic accuracy of BOLD CMR in comparison to invasively measured FFR, which served as gold standard for a hemodynamic significant coronary lesion...
  34. ncbi request reprint Sequelae of acute myocardial infarction regarding cardiac structure and function and their prognostic significance as assessed by magnetic resonance imaging
    Vinzenz Hombach
    Department of Internal Medicine II Cardiology, University of Ulm, Robert Koch Strasse 8, D 89081 Ulm, Germany
    Eur Heart J 26:549-57. 2005
    ..Because of its high spatial resolution and tissue contrast, magnetic resonance imaging (MRI) was used to assess cardiac structure and function in a large population of patients with acute myocardial infarction (AMI)...
  35. ncbi request reprint Quantification of mitral regurgitation by the proximal flow convergence method--comparison of transthoracic and transesophageal echocardiography
    Georg Grossmann
    Department of Internal Medicine, University of Ulm, Germany
    Clin Cardiol 25:517-24. 2002
    ..No dataexist to indicate whether transthoracic (TTE) and transesophageal echocardiography (TEE) are of comparable value for the detection and quantification of mitral regurgitation using the proximal flow convergence method...
  36. doi request reprint Characterization of patients with acute chest pain using cardiac magnetic resonance imaging
    Vinzenz Hombach
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    Clin Res Cardiol 97:760-7. 2008
    ....
  37. doi request reprint Everolimus-eluting stents compared with paclitaxel-eluting stents for treatment of coronary in-stent restenoses
    Sinisa Markovic
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, Ulm, Germany
    Cardiovasc Revasc Med 13:307-10. 2012
    ..We evaluated the outcome of EES compared with PES for treatment of restenosis in bare-metal and drug-eluting stents (DES)...
  38. doi request reprint Quantification of myocardial perfusion reserve at 1.5 and 3.0 Tesla: a comparison to fractional flow reserve
    Peter Bernhardt
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Int J Cardiovasc Imaging 28:2049-56. 2012
    ..76.9 %). Quantitative analysis of CMR myocardial perfusion reserve at 1.5 and 3 T is capable to detect hemodynamic significance of coronary artery stenoses. Diagnostic accuracy at 3 T is to be superior to 1.5 T...
  39. ncbi request reprint Re-angioplasty of in-stent restenosis versus balloon restenoses--a matched pair comparison
    Jochen Wohrle
    Department of Cardiology, University of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Int J Cardiol 93:257-62. 2004
    ....
  40. pmc Electrocardiographic and cardiac magnetic resonance imaging parameters as predictors of a worse outcome in patients with idiopathic dilated cardiomyopathy
    Vinzenz Hombach
    Clinic of Internal Medicine II, University Hospital Ulm, Albert Einstein Allee 23, Ulm 89081, Germany
    Eur Heart J 30:2011-8. 2009
    ..We assessed the prognostic value of cardiac magnetic resonance (CMR) parameters in addition to conventional clinical and electrocardiographic characteristics...
  41. doi request reprint Angiographic results of a Tacrolimus-eluting stent in acute coronary syndrome lesions
    Angelika Rinker
    Department of Internal Medicine II, University of Ulm, Albert Einstein Allee 23, 89081 Ulm, Germany
    Clin Res Cardiol 98:89-93. 2009
    ....
  42. doi request reprint Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial
    Ingo Eitel
    Heart Center, Department of Internal Medicine, Cardiology, University of Leipzig, Leipzig, Germany
    J Am Coll Cardiol 61:1447-54. 2013
    ....
  43. ncbi request reprint Intracoronary application of abciximab in patients with ST-elevation myocardial infarction
    Jochen Wohrle
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    EuroIntervention 3:465-9. 2008
    ..02-7.44; p<0.0001) and female gender (OR 2.05; 95%-CI 1.15-3.65, p=0.014). Conclusions: The intracoronary administration of the abciximab bolus during PCI in STEMI patients is safe and associated with a low rate of MACE at 30 days...
  44. ncbi request reprint Intravenous zanamivir for patients with pneumonitis due to pandemic (H1N1) 2009 influenza virus
    Georg Härter
    University Hospital Ulm, Dept of Clinical Infectious Diseases and Clinical immunology, Comprehensive Infectious Diseases Center Ulm and Clinic of Internal Medicine III, Albert Einstein Allee 23, 89081 Ulm, Germany
    Clin Infect Dis 50:1249-51. 2010
    ..Zanamivir given intravenously may be a therapeutic option in patients with critical illness and mechanical ventilation...