Matthias Woenckhaus

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc A patient with testicular pseudolymphoma - a rare condition mimicking malignancy: a case report
    Roman Ganzer
    Department of Urology, University of Regensburg, St Josef s Hospital, Landshuter Straße 65, 93053 Regensburg, Germany
    J Med Case Reports 1:71. 2007
  2. pmc Microsatellite analysis of pleural supernatants could increase sensitivity of pleural fluid cytology
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    J Mol Diagn 7:517-24. 2005
  3. ncbi request reprint Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, D 93053 Regensburg, Germany
    Hum Pathol 39:126-36. 2008
  4. ncbi request reprint Microsatellite instability at chromosome 8p in non-small cell lung cancer is associated with lymph node metastasis and squamous differentiation
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, Regensburg, Germany
    Int J Oncol 23:1357-63. 2003
  5. ncbi request reprint Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers
    M Woenckhaus
    Department of Pathology, University of Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    J Pathol 210:192-204. 2006
  6. pmc Nuclear and cytoplasmic Maspin expression in primary non-small cell lung cancer
    Matthias Woenckhaus
    Institute of Pathology, University of Regensburg, Regensburg, Germany
    J Clin Pathol 60:483-6. 2007
  7. ncbi request reprint Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers
    Ulrike Grepmeier
    Department of Pathology, University of Regensburg, Germany
    Int J Oncol 27:481-8. 2005
  8. ncbi request reprint Multitarget FISH and LOH analyses at chromosome 3p in non-small cell lung cancer and adjacent bronchial epithelium
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, Germany
    Am J Clin Pathol 123:752-61. 2005
  9. ncbi request reprint Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer
    Wolfgang Dietmaier
    Department of Pathology and Molecular Diagnostics, University of Regensburg, Germany
    Int J Cancer 118:2247-54. 2006
  10. ncbi request reprint Elevated nuclear maspin expression is associated with microsatellite instability and high tumour grade in colorectal cancer
    Marcus Bettstetter
    Department of Pathology, University of Regensburg, D 93053 Regensburg, Germany
    J Pathol 205:606-14. 2005

Detail Information

Publications31

  1. pmc A patient with testicular pseudolymphoma - a rare condition mimicking malignancy: a case report
    Roman Ganzer
    Department of Urology, University of Regensburg, St Josef s Hospital, Landshuter Straße 65, 93053 Regensburg, Germany
    J Med Case Reports 1:71. 2007
    ..A pseudolymphoma is a rare benign lesion which can only be distinguished from a malignant lymphoma by immuno-histochemistry and molecular-genetical investigation techniques...
  2. pmc Microsatellite analysis of pleural supernatants could increase sensitivity of pleural fluid cytology
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    J Mol Diagn 7:517-24. 2005
    ....
  3. ncbi request reprint Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, D 93053 Regensburg, Germany
    Hum Pathol 39:126-36. 2008
    ....
  4. ncbi request reprint Microsatellite instability at chromosome 8p in non-small cell lung cancer is associated with lymph node metastasis and squamous differentiation
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, Regensburg, Germany
    Int J Oncol 23:1357-63. 2003
    ..The tetranucleotide marker panel used in this study was able to indicate lymph node metastasis and high risk disease in patients with resectable squamous cell lung cancer...
  5. ncbi request reprint Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers
    M Woenckhaus
    Department of Pathology, University of Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    J Pathol 210:192-204. 2006
    ..These genes are involved in the metabolism of xenobiotics (eg GPX2 and FMO3) and may represent cigarette smoke-induced, cancer-related molecular targets that may be utilized to identify smokers with increased risk for lung cancer...
  6. pmc Nuclear and cytoplasmic Maspin expression in primary non-small cell lung cancer
    Matthias Woenckhaus
    Institute of Pathology, University of Regensburg, Regensburg, Germany
    J Clin Pathol 60:483-6. 2007
    ..To investigate whether nuclear and cytoplasmic Maspin expression is associated with distinct clinicopathological parameters and TP53 expression in a representative series of primary non-small cell lung cancer (NSCLC)...
  7. ncbi request reprint Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers
    Ulrike Grepmeier
    Department of Pathology, University of Regensburg, Germany
    Int J Oncol 27:481-8. 2005
    ..These chromosomal regions represent interesting loci for potential NSCLC associated tumor suppressor genes and could be useful as screening markers for molecular risk assessment of smokers...
  8. ncbi request reprint Multitarget FISH and LOH analyses at chromosome 3p in non-small cell lung cancer and adjacent bronchial epithelium
    Matthias Woenckhaus
    Department of Pathology, University of Regensburg, Germany
    Am J Clin Pathol 123:752-61. 2005
    ..Multicolor FISH analysis is able to detect a tumor-associated molecular field effect in bronchi adjacent to NSCLC...
  9. ncbi request reprint Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer
    Wolfgang Dietmaier
    Department of Pathology and Molecular Diagnostics, University of Regensburg, Germany
    Int J Cancer 118:2247-54. 2006
    ..Patients with negative immunohistochemical Maspin expression do not benefit from 5-FU treatment and may be candidates for an alternative (non-5-FU based) adjuvant therapy regime...
  10. ncbi request reprint Elevated nuclear maspin expression is associated with microsatellite instability and high tumour grade in colorectal cancer
    Marcus Bettstetter
    Department of Pathology, University of Regensburg, D 93053 Regensburg, Germany
    J Pathol 205:606-14. 2005
    ..013), de-differentiated tumours (p = 0.006), and at the invasion front. These findings provide new insights into the role of maspin in colorectal cancer progression and may be useful for diagnosis and treatment strategies...
  11. doi request reprint Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation
    Benedikt Gröschl
    Institute of Pathology and Molecular Pathology Diagnostic Unit, University of Regensburg, Germany
    Int J Cancer 132:1537-46. 2013
    ..Furthermore, DUSP4 overexpression led to increased proliferation in CRC cell lines. Our findings suggest that DUSP4 acts as an important regulator of cell growth within the MAPK pathway and causes enhanced cell growth in MSI-H CRC...
  12. ncbi request reprint Tissue microarray analysis of methylthioadenosine phosphorylase protein expression in melanocytic skin tumors
    Peter J Wild
    Institute of Pathology and Department of Dermatology, University of Regensburg, Germany
    Arch Dermatol 142:471-6. 2006
    ..This was not seen in the patients with MTAP-negative tumors. Conclusion Methylthioadenosine phosphorylase protein expression may be a predictive marker of interferon therapy resistance in patients with melanoma and disease progression...
  13. ncbi request reprint Vertigo and hearing disturbance as the first sign of a glioblastoma (World Health Organization grade IV)
    Anna K Licht
    Department of Otorhinolaryngology, University of Regensburg, Regensburg, Germany
    Otol Neurotol 25:174-7. 2004
    ..To describe vertigo and hearing disturbance as a first sign of glioblastoma...
  14. ncbi request reprint Association of Crohn's disease and latent celiac disease: a case report and review of the literature
    Jörg Schedel
    Department of Internal Medicine I, University Hospital of Regensburg, 93042 Regensburg, Germany
    Int J Colorectal Dis 20:376-80. 2005
    ..Celiac disease, on the other hand, is defined by histologically proven villous atrophy associated with hyperplasia of crypts, lymphocytic infiltration and clinical improvement after a gluten-free diet...
  15. ncbi request reprint Langerhans' cell histiocytosis with bilateral temporal bone involvement
    Tobias Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Germany
    Am J Otolaryngol 24:265-70. 2003
    ..The etiology of LCH remains unclear to date. It is currently believed that clonal accumulation and proliferation of CD1a-positive Langerhans' cells are causative...
  16. ncbi request reprint Renal cell carcinoma metastases to the thyroid gland-8 cases reported
    Igors Iesalnieks
    Department of Surgery, University Regensburg, Germany
    Thyroid 17:49-52. 2007
    ..Clinically important, isolated metastases to the thyroid gland is a rare occurrence. Renal cell carcinoma (RCC) is the most common primary tumor site. We report on 8 cases of late onset metachronous thyroid metastases of RCC...
  17. ncbi request reprint Unilateral adult malignant optic nerve glioma
    Bettina Wabbels
    Department of Paediatric Ophthalmology, Strabismology and Ophthalmogenetics, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 242:741-8. 2004
    ..They represent a clinical entity different from the more common childhood benign optic nerve gliomas, which are frequently associated with neurofibromatosis I...
  18. doi request reprint Contrast-enhanced ultrasound in diagnosing liver malignancy
    I Zuber-Jerger
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Clin Hemorheol Microcirc 43:109-18. 2009
    ..The aim of our study was to evaluate contrast ultrasound signs in diagnosing malignant liver lesions...
  19. doi request reprint Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases
    A Gaumann
    Institute of Pathology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042, Regensburg, Germany
    Virchows Arch 453:473-84. 2008
    ..Despite myofibroblastic phenotype, APC/beta-catenin pathway changes are rare. Cyclin D1, only expressed in the myxofibrosarcoma-type, is likely transcribed via factors other than beta-catenin...
  20. ncbi request reprint Quantitative gene expression analysis of fractalkine using laser microdissection in biopsies from kidney allografts with acute rejection
    M C Pietrzyk
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, 94042 Regensburg, Germany
    Transplant Proc 36:2659-61. 2004
    ..37 to 5.11] to 7.07 [1.19 to 73.49] (P < .01). Furthermore, there was a trend toward higher glomerular FKN expression among patients with more severe rejection. Our results suggest a role of FKN in acute renal allograft rejection...
  21. ncbi request reprint [Renal cell carcinoma metastases to the thyroid gland -- report of 3 cases and review of the literature]
    I Iesalnieks
    Klinik und Poliklinik für Chirurgie, Universitatsklinikum Regensburg
    Zentralbl Chir 131:235-9. 2006
    ..In those patients who have undergone complete resection, 5-year-survival-rates of 50 % have been reported. We describe 3 cases of surgically treated thyroid metastases of RCC, and review the literature...
  22. ncbi request reprint Defining high-fat-diet rat models: metabolic and molecular effects of different fat types
    R Buettner
    Department of Internal Medicine I, University of Regensburg, 93042 Regensburg, Germany
    J Mol Endocrinol 36:485-501. 2006
    ..Diets based on LC-SFA and MUFA induced hepatic steatosis with SREBP1c activation. This points to an intact transcriptional hepatic insulin effect despite resistance to insulin's metabolic actions...
  23. ncbi request reprint A patient with myelofibrosis complicated by refractory ascites and portal hypertension: to tips or not to tips? A case report with discussion of the mechanism of ascites formation
    R Wiest
    Dept of Internal Medicine I, University Hospital, Regensburg, Germany
    Scand J Gastroenterol 39:389-94. 2004
    ..In conclusion, TIPS may be considered as rescue management for refractory ascites secondary to portal hypertension, but caution in respect to the presence and/or development of peritoneal or other ectopic haematopoesis has to be taken...
  24. ncbi request reprint Efficient analysis of hepatic glucose output and insulin action using a liver slice culture system
    R Buettner
    Department of Internal Medicine I, University of Regensburg, Germany
    Horm Metab Res 37:127-32. 2005
    ..However, whether this method is suitable to measure hepatic glucose output is unknown...
  25. pmc Discrepancy between mRNA and protein expression of tumour suppressor maspin in synovial tissue may contribute to synovial hyperplasia in rheumatoid arthritis
    J Schedel
    Department of Internal Medicine I, Division of Rheumatology and Clinical Immunology, University Hospital of Regensburg, D 93042 Regensburg, Germany
    Ann Rheum Dis 63:1205-11. 2004
    ..To investigate the expression of maspin in RA synovial tissue and compare it with the expression in osteoarthritis (OA) and normal synovial tissue (NS)...
  26. ncbi request reprint [Autoimmune cholangitis with vasculitic ulcers, rheumatoid arthritis and IgA glomerulonephritis]
    J Schedel
    Klinik und Poliklinik für Innere Medizin I, Klinikum der Universitat Regensburg
    Dtsch Med Wochenschr 129:2409-12. 2004
    ..The patient was in a reduced general condition and cachectic nutritional state. She had slight scleral icterus, the liver being palpable 5 cm under the costal margin, edema of the lower limbs and two ulcers at the right foot...
  27. ncbi request reprint Insular carcinomas of the thyroid exhibit poor prognosis and long-term survival in comparison to follicular and papillary T4 carcinomas
    Ayman Agha
    Department of Surgery, University of Regensburg Medical Center, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Langenbecks Arch Surg 392:671-7. 2007
    ..Whether the insular component is an independent factor for poor prognosis remains unclear. Therefore, in the present study, we compared the survival of patients with advanced insular, follicular, and papillary thyroid cancer...
  28. ncbi request reprint Effectiveness of parathyroid-hormone measurement in detecting patients with multiple gland disease causing primary hyperparathyroidism
    Ayman Agha
    Department of Surgery, University Hospital of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Langenbecks Arch Surg 392:703-8. 2007
    ..The aim of the study was to evaluate the efficacy of iPTH monitoring in treating pHPT resulting from multiple gland disease...
  29. ncbi request reprint Fatty liver: imaging patterns and pitfalls
    Okka W Hamer
    Department of Diagnostic Radiology, University Hospital of Regensburg, Regensburg, Germany
    Radiographics 26:1637-53. 2006
    ..In addition, knowledge of the risk factors and the pathophysiologic, histologic, and epidemiologic features of fat accumulation may be useful for avoiding diagnostic pitfalls and planning an appropriate work-up in difficult cases...
  30. ncbi request reprint Correlation between neovascularisation and neuroendocrine differentiation in prostatic carcinoma
    R Grobholz
    Department of Pathology, Ruprecht Karls University Heidelberg, University Hospital Mannheim, Mannheim, Germany
    Pathol Res Pract 196:277-84. 2000
    ..0006). These observations support the concept that increased neovascularisation is influenced not only by poor pathological grading but also by a high NE differentiation...
  31. ncbi request reprint WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer
    Christoph Wissmann
    metaGen Pharmaceuticals GmbH, Oudenarder Strasse 16, 13347 Berlin, Germany
    J Pathol 201:204-12. 2003
    ..However, down-regulation of WIF1 correlated with higher tumour stage in urinary bladder tumours (pTa versus pT1-pT4; p = 0.038)...