Uwe A Wittel

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. pmc The pathobiological impact of cigarette smoke on pancreatic cancer development (review)
    Uwe A Wittel
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    Int J Oncol 41:5-14. 2012
  2. pmc Cigarette smoke-induced pancreatic damage: experimental data
    Uwe A Wittel
    Departement of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    Langenbecks Arch Surg 393:581-8. 2008
  3. doi request reprint Taurocholate-induced pancreatitis: a model of severe necrotizing pancreatitis in mice
    Uwe A Wittel
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    Pancreas 36:e9-21. 2008
  4. ncbi request reprint Dissecting the effect of moxifloxacin in mice with infected necrosis in taurocholate induced necrotizing pancreatitis
    Gabriel J Seifert
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
    Pancreatology 14:179-85. 2014
  5. ncbi request reprint Infected pancreatic necrosis increases the severity of experimental necrotizing pancreatitis in mice
    Philipp J Poxleitner
    From the Department of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    Pancreas 42:1150-6. 2013
  6. doi request reprint Systemic differential gene regulation of the inter-α-trypsin inhibitor family in acute necrotizing pancreatitis in mice
    Gabriel Seifert
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    J Surg Res 180:e83-90. 2013
  7. ncbi request reprint Influence of PMN leukocyte-mediated pancreatic damage on the systemic immune response in severe acute pancreatitis in rats
    Uwe A Wittel
    Department of General, Visceral, and Transplantation Surgery, University of Freiburg, 79106 Freiburg, Germany
    Dig Dis Sci 49:1348-57. 2004
  8. ncbi request reprint Oxygen radical production precedes alcohol-induced acute pancreatitis in rats
    Uwe A Wittel
    Department of General Surgery, University of Ulm, Ulm, Germany
    Pancreas 26:e74-80. 2003
  9. ncbi request reprint Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats
    Uwe A Wittel
    Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska 68198 5870, USA
    Am J Gastroenterol 101:148-59. 2006

Collaborators

Detail Information

Publications9

  1. pmc The pathobiological impact of cigarette smoke on pancreatic cancer development (review)
    Uwe A Wittel
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    Int J Oncol 41:5-14. 2012
    ..This sheds new light on cigarette smoke-induced acinar cell damage. On this background, our objective is to outline a multifactorial model of tobacco smoke-induced pancreatic carcinogenesis...
  2. pmc Cigarette smoke-induced pancreatic damage: experimental data
    Uwe A Wittel
    Departement of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    Langenbecks Arch Surg 393:581-8. 2008
    ..Despite of this clear epidemiological correlation, cigarette smoke-induced pancreatic damage has only been investigated in a small number of experimental studies...
  3. doi request reprint Taurocholate-induced pancreatitis: a model of severe necrotizing pancreatitis in mice
    Uwe A Wittel
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    Pancreas 36:e9-21. 2008
    ....
  4. ncbi request reprint Dissecting the effect of moxifloxacin in mice with infected necrosis in taurocholate induced necrotizing pancreatitis
    Gabriel J Seifert
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
    Pancreatology 14:179-85. 2014
    ....
  5. ncbi request reprint Infected pancreatic necrosis increases the severity of experimental necrotizing pancreatitis in mice
    Philipp J Poxleitner
    From the Department of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    Pancreas 42:1150-6. 2013
    ..To examine mechanisms underlying this clinical observation, we developed and tested a model, in which primary infection of necrosis is achieved in taurocholate-induced pancreatitis in mice...
  6. doi request reprint Systemic differential gene regulation of the inter-α-trypsin inhibitor family in acute necrotizing pancreatitis in mice
    Gabriel Seifert
    Department of General and Visceral Surgery, Universitatsklinik Freiburg, Freiburg, Germany
    J Surg Res 180:e83-90. 2013
    ..We investigated the differential gene expression in typically affected organs in a mouse model of severe necrotizing pancreatitis...
  7. ncbi request reprint Influence of PMN leukocyte-mediated pancreatic damage on the systemic immune response in severe acute pancreatitis in rats
    Uwe A Wittel
    Department of General, Visceral, and Transplantation Surgery, University of Freiburg, 79106 Freiburg, Germany
    Dig Dis Sci 49:1348-57. 2004
    ..Only the treatment with anti-ICAM-1 mAb affected these changes, indicating that immunological changes in necrotizing pancreatitis are only in part affected by early PMN leukocyte-mediated pancreatic damage...
  8. ncbi request reprint Oxygen radical production precedes alcohol-induced acute pancreatitis in rats
    Uwe A Wittel
    Department of General Surgery, University of Ulm, Ulm, Germany
    Pancreas 26:e74-80. 2003
    ..Ethanol is involved in approximately 40% of the cases of acute pancreatitis...
  9. ncbi request reprint Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats
    Uwe A Wittel
    Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska 68198 5870, USA
    Am J Gastroenterol 101:148-59. 2006
    ..In the present study, we investigated the effect of cigarette smoke inhalation on the pancreas...