Claus Wittekindt

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint Immunohistochemical expression of VEGF and VEGF receptors in nasal polyps as compared to normal turbinate mucosa
    Claus Wittekindt
    Department of Otorhinolaryngology, University of Koln, Joseph Stelzmannstr 9, 50924 Köln, Germany
    Eur Arch Otorhinolaryngol 259:294-8. 2002
  2. ncbi request reprint Botulinum toxin A for neuropathic pain after neck dissection: a dose-finding study
    Claus Wittekindt
    Department of Otorhinolaryngology, School of Medicine, Cologne, Germany
    Laryngoscope 116:1168-71. 2006
  3. ncbi request reprint Immunohistochemistry of whole-organ sections of advanced human laryngeal cancer
    Claus Wittekindt
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Kerpener Str 62, 50924, Cologne, Germany
    Eur Arch Otorhinolaryngol 263:741-6. 2006
  4. ncbi request reprint Expression of p16 protein is associated with human papillomavirus status in tonsillar carcinomas and has implications on survival
    Claus Wittekindt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, Cologne, Germany
    Adv Otorhinolaryngol 62:72-80. 2005
  5. ncbi request reprint [ANCA-negative subglottic laryngeal stenosis in childhood]
    C Wittekindt
    Klinik und Poliklinik Fur Hals, Nasen, Ohren Heilkunde, Kopf und Hals Chirurgie am Klinikum der Universität zu Köln
    HNO 55:807-11. 2007
  6. ncbi request reprint Lymphatic malformations of the head and neck: introduction of a disease score for children, Cologne Disease Score (CDS)
    Claus Wittekindt
    Clinic of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    Int J Pediatr Otorhinolaryngol 70:1205-12. 2006
  7. ncbi request reprint [Vascularized tumor of the scalp]
    C Wittekindt
    Klinik und Poliklinik Fur Hals, Nasen und Ohrenkrankenheiten, Universitat, Cologne
    HNO 51:737-8. 2003
  8. ncbi request reprint Duplication of the external auditory canal: a report of three cases
    C Wittekindt
    Department of Otorhinolaryngology, University of Cologne, Cologne, Germany
    Int J Pediatr Otorhinolaryngol 58:179-84. 2001
  9. ncbi request reprint Rupture of the larynx in a newborn
    Claus Wittekindt
    Departments of Otorhinolaryngology and Neonatology, Children s Hospital, University of Cologne, Cologne, Germany
    Obstet Gynecol 99:904-6. 2002
  10. doi request reprint Prognostic impact of pretherapeutic laboratory values in head and neck cancer patients
    Franziska Peter
    Department of Otorhinolaryngology, Jena University Hospital, Lessingstrasse 2, 07740 Jena, Germany
    J Cancer Res Clin Oncol 139:171-8. 2013

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Immunohistochemical expression of VEGF and VEGF receptors in nasal polyps as compared to normal turbinate mucosa
    Claus Wittekindt
    Department of Otorhinolaryngology, University of Koln, Joseph Stelzmannstr 9, 50924 Köln, Germany
    Eur Arch Otorhinolaryngol 259:294-8. 2002
    ..These findings support a role for VEGF and its receptors, VEGFR-1 and VEGFR-2, in the development and perpetuation of edema and angiogenesis in nasal polyps...
  2. ncbi request reprint Botulinum toxin A for neuropathic pain after neck dissection: a dose-finding study
    Claus Wittekindt
    Department of Otorhinolaryngology, School of Medicine, Cologne, Germany
    Laryngoscope 116:1168-71. 2006
    ..Botulinum toxin type A (BtxA) has been reported to be feasible in chronic neuropathic pain after neck dissection. The impact of the dose on the outcome has not been investigated yet...
  3. ncbi request reprint Immunohistochemistry of whole-organ sections of advanced human laryngeal cancer
    Claus Wittekindt
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Kerpener Str 62, 50924, Cologne, Germany
    Eur Arch Otorhinolaryngol 263:741-6. 2006
    ..By analyzation of color-coded fusion images the spatial expression of the respective antibodies could be visualized...
  4. ncbi request reprint Expression of p16 protein is associated with human papillomavirus status in tonsillar carcinomas and has implications on survival
    Claus Wittekindt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, Cologne, Germany
    Adv Otorhinolaryngol 62:72-80. 2005
    ..02). These data indicate that p16 is a technically simple immunohistological marker, applicable for routine pathological histology, and its prognostic value for survival is fully equivalent to HPV DNA detection...
  5. ncbi request reprint [ANCA-negative subglottic laryngeal stenosis in childhood]
    C Wittekindt
    Klinik und Poliklinik Fur Hals, Nasen, Ohren Heilkunde, Kopf und Hals Chirurgie am Klinikum der Universität zu Köln
    HNO 55:807-11. 2007
    ..Surgical interventions within the larynx or trachea might only be considered after ineffective therapy with immunosuppressive drugs...
  6. ncbi request reprint Lymphatic malformations of the head and neck: introduction of a disease score for children, Cologne Disease Score (CDS)
    Claus Wittekindt
    Clinic of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    Int J Pediatr Otorhinolaryngol 70:1205-12. 2006
    ..A clinical staging system for children with lymphatic malformations that would allow for a standardized comparison of disease and treatment outcomes...
  7. ncbi request reprint [Vascularized tumor of the scalp]
    C Wittekindt
    Klinik und Poliklinik Fur Hals, Nasen und Ohrenkrankenheiten, Universitat, Cologne
    HNO 51:737-8. 2003
  8. ncbi request reprint Duplication of the external auditory canal: a report of three cases
    C Wittekindt
    Department of Otorhinolaryngology, University of Cologne, Cologne, Germany
    Int J Pediatr Otorhinolaryngol 58:179-84. 2001
    ..In this retrospective study, clinical features and anatomical relationships are described in three pediatric cases. Therapeutical guidelines for surgical management of first branchial cleft anomalies are discussed...
  9. ncbi request reprint Rupture of the larynx in a newborn
    Claus Wittekindt
    Departments of Otorhinolaryngology and Neonatology, Children s Hospital, University of Cologne, Cologne, Germany
    Obstet Gynecol 99:904-6. 2002
    ..Lesions of the laryngotrachea due to repeated intubation trauma after birth are reported...
  10. doi request reprint Prognostic impact of pretherapeutic laboratory values in head and neck cancer patients
    Franziska Peter
    Department of Otorhinolaryngology, Jena University Hospital, Lessingstrasse 2, 07740 Jena, Germany
    J Cancer Res Clin Oncol 139:171-8. 2013
    ..We investigated whether HNC and its comorbidity also influence routine laboratory values and whether these values have influence on overall survival...
  11. doi request reprint Electromyographic facial nerve monitoring during parotidectomy for benign lesions does not improve the outcome of postoperative facial nerve function: a prospective two-center trial
    Maria Grosheva
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Jena, Germany
    Laryngoscope 119:2299-305. 2009
    ..To analyze the benefit of electromyographic (EMG) neuromonitoring during primary surgery on benign parotid lesions for postoperative facial function compared to visual observation only...
  12. ncbi request reprint Mapping of Ki-67 protein distribution on whole organ serial sections of the larynx
    Claus Wittekindt
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Jena, Jena, Germany
    Acta Otolaryngol 128:207-12. 2008
    ..Immunostaining of whole organ serial sections of the larynx is feasible and will allow analysis of cellular alterations in the undisturbed anatomical context of whole organ serial sections of the larynx...
  13. ncbi request reprint Impact of lateral parotidectomy for benign tumors on quality of life
    Dirk Beutner
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    Acta Otolaryngol 126:1091-5. 2006
    ..This study supports the use of lateral parotidectomy as a safe and standardized type of surgery for benign parotid gland disease...
  14. ncbi request reprint Recurrent pleomorphic adenoma of the parotid gland: analysis of 108 consecutive patients
    Claus Wittekindt
    Clinic of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, D 50924 Cologne, Germany
    Head Neck 29:822-8. 2007
    ..Surgery for recurrent parotid pleomorphic adenoma is a challenging problem...
  15. ncbi request reprint Short-term outcome and patient satisfaction after sialendoscopy
    Tobias Kroll
    Department of Otolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Justus Liebig University Giessen, Campus Giessen, Klinikstrasse 33, 35392, Giessen, Germany
    Eur Arch Otorhinolaryngol 270:2939-45. 2013
    ..There seems to be a high patient satisfaction in these selected cases. The duration of preoperative symptoms appears to be an important factor predisposing towards poor satisfaction. ..
  16. doi request reprint Botulinum toxin type b for the treatment of a sialocele after parotidectomy
    Mira Pantel
    Department of Otorhinolaryngology, University Hospital, Friedrich Schiller University Jena, Jena, Germany
    Head Neck 35:E11-2. 2013
    ..The sialocele was effectively treated by a single injection with botulinum toxin type B combined with multiple needle aspirations...
  17. doi request reprint Diversity of treatment of T2N0 glottic cancer of the larynx: lessons to learn from epidemiological cancer registry data
    Mira Pantel
    Department of Otorhinolaryngology, University Hospital, Friedrich Schiller University Jena, Jena, Germany
    Acta Otolaryngol 131:1205-13. 2011
    ..This should be the basis for future treatment standardization. Obligatory documentation of the R status and cause of death in the cancer registries will improve the data interpretation in the future...
  18. ncbi request reprint High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases
    Jens Peter Klussmann
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    Acta Otolaryngol 126:1213-7. 2006
    ..We identified smoking as a significant risk factor for multilocular Warthin tumor development. Therefore, we recommend taking history of smoking into account when making the decisions for surgical strategy...
  19. ncbi request reprint Submandibular gland excision: 15 years of experience
    Simon Florian Preuss
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    J Oral Maxillofac Surg 65:953-7. 2007
    ..The aim of this study was to review a single institution's experience of a nonselected case series of submandibular gland excision over 15 years...
  20. doi request reprint Evaluation of peripheral vocal cord paralysis by electromyography
    Maria Grosheva
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Germany
    Laryngoscope 118:987-90. 2008
    ..To analyze the predictive value of electromyography (EMG) after peripheral vocal cord paralysis and to estimate regeneration time...
  21. doi request reprint Carcinoma ex pleomorphic adenoma of the parotid gland. Study and implications for diagnostics and therapy
    Jan Christoffer Luers
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Cologne, Cologne, Germany
    Acta Oncol 48:132-6. 2009
    ..Prognosis is thought to be poorer than for other parotid malignancies. We sought to describe a general diagnostic and therapy strategy and assess factors predicting the outcome...
  22. doi request reprint Safety and efficacy of botulinum toxin therapy in otorhinolaryngology: experience from 1,000 treatments
    Victor Helmstaedter
    Department of Otorhinolaryngology Head and Neck Surgery, University of Cologne, Cologne, Germany
    Laryngoscope 118:790-6. 2008
    ....
  23. doi request reprint Stent migration to the ileum: a potentially lethal complication after Montgomery salivary bypass tube placement for hypopharyngeal stenosis after laryngectomy
    Thomas Bitter
    Department of Otorhinolaryngology, Friedrich Schiller University, Jena, Germany
    Head Neck 34:135-7. 2012
    ..Generally, MSBT use is not associated with serious complications. Only a small number of cases with severe MSBT-associated complications have been reported in the literature...
  24. ncbi request reprint New aspects in parotid gland surgery
    Eberhard Stennert
    Clinic of Oto Rhino Laryngology, Head and Neck Surgery, University of Cologne, Germany
    Otolaryngol Pol 58:109-14. 2004
    ..Of the 139 patients with clinical N0 neck 45% had occult neck metastasis. In conclusion neck dissection should be considered as an integral part of the surgical concept in major salivary gland cancer patients...
  25. ncbi request reprint Is there a need for positron emission tomography imaging to stage the N0 neck in T1-T2 squamous cell carcinoma of the oral cavity or oropharynx?
    Ursula Schroeder
    Department of Otolaryngology Head and Neck Surgery, University of Cologne Medical Center, Cologne, Germany
    Ann Otol Rhinol Laryngol 117:854-63. 2008
    ....
  26. ncbi request reprint Successful OK-432 therapy for a supraclavicular lymphocele: report of a case
    Simon Florian Preuss
    Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, University of Cologne, Josef Stelzmann Str 9, 50924, Cologne, Germany
    Eur Arch Otorhinolaryngol 263:692-4. 2006
    ..Thus, intralesional application of OK-432 is considered a highly effective treatment for cystic masses such as lymphoceles...
  27. doi request reprint Expression of matrix metalloproteinase-9 (MMP-9) and blood vessel density in laryngeal squamous cell carcinomas
    Claus Wittekindt
    Department of Otorhinolaryngology, Justus Liebig University, Giessen, Germany
    Acta Otolaryngol 131:101-6. 2011
    ..In this study we found that inflammatory cells may be a source of MMP-9 in laryngeal cancer. MMP-9 was correlated with blood vessel density. MMP-9 may be a potential target to disrupt tumor neovascularization...
  28. ncbi request reprint Successful adjuvant tamoxifen therapy for estrogen receptor-positive metastasizing sweat gland adenocarcinoma: need for a clinical trial?
    Ursula Schröder
    Clinic of Otorhinolaryngology Head and Neck Surgery, University of Cologne, Cologne, Germany
    Ann Otol Rhinol Laryngol 113:242-4. 2004
    ..We suggest examining the hormone receptor expression in these neoplasms regularly. A prospective study should be commenced to assess the benefit of adjuvant antihormonal therapy in eccrine gland adenocarcinomas...
  29. ncbi request reprint The role of growth factors for disease and therapy in diseases of the head and neck
    O Guntinas-Lichius
    Clinic of Otolaryngology, Head and Neck Surgery, University of Cologne, Germany
    DNA Cell Biol 22:593-606. 2003
    ..This review provides a brief account of what we know regarding growth factors in otorhinolaryngology, particularly in the field of otology, wound healing, oncology, peripheral nerve regeneration, and rhinology...
  30. ncbi request reprint Hoarseness after laryngeal blunt trauma: a differential diagnosis between an injury to the external branch of the superior laryngeal nerve and an arytenoid subluxation. A case report and literature review
    U Schroeder
    ENT Department, University of Cologne, Joseph Stelzmann Str 9, 50924, Cologne, Germany
    Eur Arch Otorhinolaryngol 260:304-7. 2003
    ..Although the clinical findings are familiar sequelae of thyroid surgery, they may be misdiagnosed as arytenoid subluxation after laryngeal blunt trauma. Stroboscopy and electromyography permitted the correct diagnosis...
  31. ncbi request reprint [Chronic-persistent infection of the auricle]
    G Quante
    Klinik und Poliklinik Fur Hals, Nasen, Ohren Heilkunde, Kopf und Hals Chirurgie, Universitätsklinikum Köln
    HNO 54:35-6. 2006
  32. ncbi request reprint Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF-receptors Flt-1 and KDR/Flk-1 in the vestibule of guinea pigs
    A Hess
    Department of Oto Rhino Laryngology, University of Cologne, Joseph Stelzmannstr 9, D 50924, Cologne, France
    Neurosci Lett 280:147-50. 2000
    ..These findings give evidence that VEGF, Flt-1 and KDR/Flk-1 are constitutively expressed in the vestibule...
  33. ncbi request reprint Textured polydimethylsiloxane elastomers in the human larynx: safety and efficiency of use
    C Sittel
    Department of Otorhinolaryngology Head and Neck Surgery, University of Cologne, Germany
    J Biomed Mater Res 53:646-50. 2000
    ..Their use is a valuable and safe alternative when a definitive one-step procedure seems advantageous. However, further studies are needed to assess voice improvement in comparison to other materials...
  34. ncbi request reprint Detection of extracellular signal-regulated kinase1/2 in the inner ear of guinea pigs
    A Hess
    Department of Oto Rhino Laryngology, University of Cologne, Joseph Stelzmannstrasse 9, D 50924, Cologne, Germany
    Neurosci Lett 289:72-4. 2000
    ..These findings provide evidence that activated ERK1/2, as a general downstream signal of growth factors, may be contributed in the inner ear physiology...
  35. pmc Nuclear survivin expression is associated with HPV-independent carcinogenesis and is an indicator of poor prognosis in oropharyngeal cancer
    S F Preuss
    Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, University Hospital of Cologne, Cologne, Germany
    Br J Cancer 98:627-32. 2008
    ..975; 95% CI=2.377-107.360; P=0.004, respectively). Our data show that nuclear accumulation of survivin correlates with HPV-independent carcinogenesis and is an independent predictor of poor survival in patients with OSCC...
  36. ncbi request reprint Long-term results of the combined modality therapy for advanced cervical metastatic head and neck squamous cell carcinoma
    S F Preuss
    Department of Otorhinolaryngology, Head and Neck Surgery, Medical School, University of Cologne, Josef Stelzmann Str 9, 50924 Cologne, Germany
    Eur J Surg Oncol 33:358-63. 2007
    ..The aim of this retrospective study was to investigate the outcome of these patients uniformely using a strategy which consists of surgery for the primary tumor and the neck metastases followed by postoperative radio(chemo)therapy...
  37. ncbi request reprint [HPV-associated tonsillar cancer. An update]
    J P Klussmann
    Klinik und Poliklinik für Hals Nasen Ohren Heilkunde des Klinikum der Universität zu Köln, Cologne
    HNO 52:208-18. 2004
    ..New insights and increasing evidence for the analogy of HPV-positive HNSCC with cervical cancer are discussed. The definition of HPV-positive HNSCC has become more important due to the implications for risk factors and prognosis...
  38. ncbi request reprint [An accessory retropharyngeal bone as a rare cause of dysphagia]
    D Beutner
    Universitäts HNO Klinik Köln
    HNO 54:473-4, 476. 2006
    ..Dysphagia due to cervical spine osteophytes, Forestier's disease or progressive ossifying fibrodysplasia is well known. This case adds an isolated retropharyngeal bone formation as a rare cause of dysphagia to the literature...
  39. ncbi request reprint [Indolent neck tumour. A 47 year old patient with a painless tumour in the area of the left mandibular angle]
    S F Preuss
    Klinik und Poliklinik Fur Hals, Nasen, Ohrenheilkunde, Universitat zu Koln
    HNO 53:876-8. 2005
  40. ncbi request reprint [Painful swelling of the soft tissue of the neck]
    D Beutner
    Universitäts HNO Klinik Köln
    HNO 53:637-8. 2005
  41. ncbi request reprint Pyoderma gangrenosum in the head and neck
    Claus Wittekindt
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Cologne, Cologne, Germany
    Arch Otolaryngol Head Neck Surg 133:83-5. 2007
  42. doi request reprint Postoperative pain assessment after functional endoscopic sinus surgery (FESS) for chronic pansinusitis
    Mira Finkensieper
    Department of Otorhinolaryngology, University Hospital Jena, Lessingstrasse 2, 07740, Jena, Germany
    Eur Arch Otorhinolaryngol 270:157-66. 2013
    ..We conclude that QUIPS could help to optimize the quality of postoperative pain management following FESS...
  43. ncbi request reprint Parotidectomy for benign parotid disease at a university teaching hospital: outcome of 963 operations
    Orlando Guntinas-Lichius
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Koeln, Germany
    Laryngoscope 116:534-40. 2006
    ..All teaching operations were performed under strict microscopic control and supervision of experienced surgeons...
  44. ncbi request reprint Prognostic value of electroneurography and electromyography in facial palsy
    Maria Grosheva
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    Laryngoscope 118:394-7. 2008
    ..To compare the prognostic value of electroneurography (ENG) and needle electromyography (EMG) to estimate facial function outcome after acute facial palsy...
  45. ncbi request reprint Management of bilateral arytenoid cartilage fixation versus recurrent laryngeal nerve paralysis
    Hans Edmund Eckel
    Department of Otorhinolaryngology, University of Cologne Medical School, Cologne, Germany
    Ann Otol Rhinol Laryngol 112:103-8. 2003
    ..Additional sites of stenosis were more frequent in ACF patients. Stenosis due to RLNP could be managed endoscopically without preliminary tracheotomy, while ACF frequently required open surgery and temporary tracheotomy...
  46. ncbi request reprint Radiology quiz case 1: Intracranial schwannoma originating from the greater petrosal nerve
    Claus Wittekindt
    University of Cologne, Cologne, Germany
    Arch Otolaryngol Head Neck Surg 132:102, 104. 2006
  47. ncbi request reprint Recurrent pleomorphic adenoma of the parotid gland: a prospective histopathological and immunohistochemical study
    Eberhard Stennert
    Department of Otolaryngology Head and Neck Surgery, University of Cologne, Koeln, Germany
    Laryngoscope 114:158-63. 2004
    ..Histopathological characteristics and proliferation indices of recurrent pleomorphic adenoma were described in a series of 31 patients who were referred to the authors' clinic for revision surgery...
  48. doi request reprint Prognostic value of anterior rhinomanometry in diode laser turbinoplasty
    Gerd Fabian Volk
    Department of Otorhinolaryngology, Friedrich Schiller Universitat, Lessingstraße 2, D 07743 Jena, Germany
    Arch Otolaryngol Head Neck Surg 136:1015-9. 2010
    ..To identify objective criteria predicting the success of diode laser-assisted turbinoplasty...
  49. pmc Basics of tumor development and importance of human papilloma virus (HPV) for head and neck cancer
    Claus Wittekindt
    University Hospital Giessen and Marburg, Department of Otorhinolaryngology, Head and Neck Surgery, Giessen, Germany
    GMS Curr Top Otorhinolaryngol Head Neck Surg 11:Doc09. 2012
    ..Future therapy concepts may vary for the two subgroups of patients, particularly patients with HPV-associated OSCC may take advantage of less aggressive treatments. Finally, an outlook will be given on possible targeted therapies...
  50. ncbi request reprint Complications of suspension laryngoscopy
    Jens Peter Klussmann
    Department of Otorhinolaryngology Head and Neck Surgery, University of Cologne, Cologne, Germany
    Ann Otol Rhinol Laryngol 111:972-6. 2002
    ..Although minor complications frequently occur during SL, it is a relatively safe procedure with a low risk of significant morbidity...
  51. doi request reprint [Diagnostic and therapy of salivary gland diseases: relevant aspects for the pathologist from the clinical perspective]
    C Wittekindt
    Klinik und Poliklinik Fur Hals, Nasen, Ohrenheilkunde, Universitatsklinikum, Friedrich Schiller Universitat, Lessingstr 2, 07740 Jena
    Pathologe 30:424-31. 2009
    ..Intraglandular injections have been shown to induce salivary gland atrophy in animal experiments. The availability of biologicals is currently yielding new aspects for the treatment of Sjögren's disease...
  52. ncbi request reprint [Permeability of the round window membrane for prednisolone-21-hydrogen succinate. Prednisolone content of the perilymph after local administration vs. systemic injection]
    G Bachmann
    , Nasen, Ohrenheilkunde,
    HNO 49:538-42. 2001
    ..After application of 5 mg, the levels of prednisolone are measurable up to 16 h...
  53. doi request reprint In reference to limited parotidectomy: the role of extracapsular dissection in parotid gland neoplasms
    Dirk Beutner
    Laryngoscope 118:379; author reply 379-80. 2008