Joachim Wistuba

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. doi request reprint Animal models for Klinefelter's syndrome and their relevance for the clinic
    Joachim Wistuba
    Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University Clinics, Domagkstrasse 11, 48149 Munster, Germany
    Mol Hum Reprod 16:375-85. 2010
  2. doi request reprint Experimental endocrine manipulation by contraceptive regimen in the male marmoset (Callithrix jacchus)
    Joachim Wistuba
    Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Munster, Albert Schweitzer Campus 1, 48129 Munster, Germany
    Reproduction 145:439-51. 2013
  3. ncbi request reprint Male congenital hypothyroid Pax8-/- mice are infertile despite adequate treatment with thyroid hormone
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, Domagkstr 11, 48149 Munster, Germany
    J Endocrinol 192:99-109. 2007
  4. doi request reprint Male 41, XXY* mice as a model for klinefelter syndrome: hyperactivation of leydig cells
    Joachim Wistuba
    Centre of Reproductive Medicine and Andrology, University Clinics, Domagkstrasse 11, 48149 Muenster, Germany
    Endocrinology 151:2898-910. 2010
  5. ncbi request reprint Meiosis in autologous ectopic transplants of immature testicular tissue grafted to Callithrix jacchus
    Joachim Wistuba
    Institute of Reproductive Medicine, University Munster, 48129 Munster, Germany
    Biol Reprod 74:706-13. 2006
  6. ncbi request reprint Changes in endocrine profile and reproductive organs during puberty in the male marmoset monkey (Callithrix jacchus)
    Ramesh K Chandolia
    Institute for Reproductive Medicine of the University, Domagkstr 11, D 48129 Muenster, Germany
    Reproduction 132:355-63. 2006
  7. doi request reprint New horizons for in vitro spermatogenesis? An update on novel three-dimensional culture systems as tools for meiotic and post-meiotic differentiation of testicular germ cells
    Jan Bernd Stukenborg
    Institute of Reproductive and Regenerative Biology of the Centre of Reproductive Medicine and Andrology, University Munster, Domagkstrasse 11 48129, Munster, Germany
    Mol Hum Reprod 15:521-9. 2009
  8. doi request reprint Impaired recognition memory in male mice with a supernumerary X chromosome
    Lars Lewejohann
    Department of Behavioural Biology, University of Munster, Munster, Germany
    Physiol Behav 96:23-9. 2009
  9. ncbi request reprint Norethisterone enanthate has neither a direct effect on the testis nor on the epididymis: a study in adult male cynomolgus monkeys (Macaca fascicularis)
    Aris Junaidi
    Institute of Reproductive Medicine of the University, Munster, Germany
    Eur J Endocrinol 152:655-61. 2005
  10. doi request reprint Complete spermatogenesis in orthotopic but not in ectopic transplants of autologously grafted marmoset testicular tissue
    C Marc Luetjens
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, Munster, Germany
    Endocrinology 149:1736-47. 2008

Collaborators

Detail Information

Publications27

  1. doi request reprint Animal models for Klinefelter's syndrome and their relevance for the clinic
    Joachim Wistuba
    Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University Clinics, Domagkstrasse 11, 48149 Munster, Germany
    Mol Hum Reprod 16:375-85. 2010
    ....
  2. doi request reprint Experimental endocrine manipulation by contraceptive regimen in the male marmoset (Callithrix jacchus)
    Joachim Wistuba
    Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University of Munster, Albert Schweitzer Campus 1, 48129 Munster, Germany
    Reproduction 145:439-51. 2013
    ..In conclusion, marmosets showed a different response to regimens of male contraception from macaques or men and have to be considered as a problematic model for preclinical trials of male hormonal contraception...
  3. ncbi request reprint Male congenital hypothyroid Pax8-/- mice are infertile despite adequate treatment with thyroid hormone
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, Domagkstr 11, 48149 Munster, Germany
    J Endocrinol 192:99-109. 2007
    ..It remains to be elucidated whether congenital hypothyroid male patients with mutations in the Pax8 gene are similarly affected...
  4. doi request reprint Male 41, XXY* mice as a model for klinefelter syndrome: hyperactivation of leydig cells
    Joachim Wistuba
    Centre of Reproductive Medicine and Andrology, University Clinics, Domagkstrasse 11, 48149 Muenster, Germany
    Endocrinology 151:2898-910. 2010
    ..We suggest that the embedding of Leydig cells into the changed testicular environment in 41 XX(Y)* males as such influences their endocrine function...
  5. ncbi request reprint Meiosis in autologous ectopic transplants of immature testicular tissue grafted to Callithrix jacchus
    Joachim Wistuba
    Institute of Reproductive Medicine, University Munster, 48129 Munster, Germany
    Biol Reprod 74:706-13. 2006
    ..Further studies have to be performed to overcome the meiotic arrest to explore the model further and to develop therapeutic options...
  6. ncbi request reprint Changes in endocrine profile and reproductive organs during puberty in the male marmoset monkey (Callithrix jacchus)
    Ramesh K Chandolia
    Institute for Reproductive Medicine of the University, Domagkstr 11, D 48129 Muenster, Germany
    Reproduction 132:355-63. 2006
    ....
  7. doi request reprint New horizons for in vitro spermatogenesis? An update on novel three-dimensional culture systems as tools for meiotic and post-meiotic differentiation of testicular germ cells
    Jan Bernd Stukenborg
    Institute of Reproductive and Regenerative Biology of the Centre of Reproductive Medicine and Andrology, University Munster, Domagkstrasse 11 48129, Munster, Germany
    Mol Hum Reprod 15:521-9. 2009
    ..Further research efforts are required to reveal the applicability of this culture technique for human germ cells and the functionality of the spermatozoa for generating offspring...
  8. doi request reprint Impaired recognition memory in male mice with a supernumerary X chromosome
    Lars Lewejohann
    Department of Behavioural Biology, University of Munster, Munster, Germany
    Physiol Behav 96:23-9. 2009
    ..We suggest that the altered endocrine state and/or changes in the dosage of X-linked genes in the XX(Y*) mouse model affect brain function, in particular those regions responsible for cognition and learning behavior...
  9. ncbi request reprint Norethisterone enanthate has neither a direct effect on the testis nor on the epididymis: a study in adult male cynomolgus monkeys (Macaca fascicularis)
    Aris Junaidi
    Institute of Reproductive Medicine of the University, Munster, Germany
    Eur J Endocrinol 152:655-61. 2005
    ..If NETE has a direct effect on spermatogenesis and/or epididymal function, some changes in testicular histology, sperm motility and/or morphology should occur soon after exposure to NETE...
  10. doi request reprint Complete spermatogenesis in orthotopic but not in ectopic transplants of autologously grafted marmoset testicular tissue
    C Marc Luetjens
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, Munster, Germany
    Endocrinology 149:1736-47. 2008
    ..Autologous grafting of nonhuman primate testicular tissues can result in complete spermatogenesis. Our findings indicate that transplantation site and developmental age of the tissue play a role more important than the endocrine milieu...
  11. ncbi request reprint LHR splicing variants and gene expression in the marmoset monkey
    Caroline Michel
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, D 48149 Muenster, Germany
    Mol Cell Endocrinol 279:9-15. 2007
    ..We conclude that LHR splicing in the marmoset displays a homogenous pattern and that the main function of the LHR is established in the testis, reaching its highest efficiency during pubertal maturation...
  12. ncbi request reprint Coculture of spermatogonia with somatic cells in a novel three-dimensional soft-agar-culture-system
    Jan Bernd Stukenborg
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, 48129 Munster, Germany
    J Androl 29:312-29. 2008
    ..We conclude that our enrichment and culture approach is highly useful for exploration of SSC expansion and have found indications that the system supports differentiation up to the level of postmeiotic germ cells...
  13. doi request reprint Comparative marker analysis after isolation and culture of testicular cells from the immature marmoset
    Silvia Albert
    Center of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, Albert Schweitzer Campus 1, University of Munster, Munster, Germany
    Cells Tissues Organs 196:543-54. 2012
    ..The PTC culture system established in this study will facilitate the identification of factors influencing male sex differentiation and spermatogenesis...
  14. ncbi request reprint Pharmacokinetics and pharmacodynamics of injectable testosterone undecanoate in castrated cynomolgus monkeys (Macaca fascicularis) are independent of different oil vehicles
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, Munster, Germany
    J Med Primatol 34:178-87. 2005
    ..The results suggest that TU in soybean oil produces similar effects as TU in the other vehicles. This study in non-human primates provides no objection to testing of this new preparation in humans...
  15. ncbi request reprint Organization of seminiferous epithelium in primates: relationship to spermatogenic efficiency, phylogeny, and mating system
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, D 48149 Munster, Germany
    Biol Reprod 69:582-91. 2003
    ..We speculate that the presence of a single-stage/multistage organization might simply reflect germ cell clonal size. Our findings further indicate that sperm competition in primates is not reflected at the level of testicular function...
  16. ncbi request reprint Cografting of hamster (Phodopus sungorus) and marmoset (Callithrix jacchus) testicular tissues into nude mice does not overcome blockade of early spermatogenic differentiation in primate grafts
    Joachim Wistuba
    Institute of Reproductive Medicine, University Munster, 48129 Munster, Germany
    Biol Reprod 71:2087-91. 2004
    ..Our results indicate that the conditions needed for initiation of spermatogenesis in the marmoset are remarkably different from those present in most other mammals...
  17. ncbi request reprint A new subclass of the luteinizing hormone/chorionic gonadotropin receptor lacking exon 10 messenger RNA in the New World monkey (Platyrrhini) lineage
    Jorg Gromoll
    Institute of Reproductive Medicine of the University, University of Munster, D 48129 Munster, Germany
    Biol Reprod 69:75-80. 2003
    ..In addition, the high expression of CG beta in the marmoset pituitary suggests a physiological role of CG in the reproductive function of these primates beyond pregnancy...
  18. ncbi request reprint Primate spermatogenesis: new insights into comparative testicular organisation, spermatogenic efficiency and endocrine control
    C Marc Luetjens
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, D 48129 Minster, Germany
    Biol Rev Camb Philos Soc 80:475-88. 2005
    ..In summary, key spermatogenic features are preserved across all primate taxa whereas male reproductive endocrinology features appear substantially different in the neotropical primates compared to other primate lineages...
  19. ncbi request reprint Minutes of the 14th European workshop on molecular and cellular endocrinology of the testis
    Jorg Gromoll
    Institute of Reproductive Medicine of the University, Domagkstrasse 11, D 48129 Munster, Germany
    Mol Cell Endocrinol 257:1-5. 2006
  20. ncbi request reprint Transgenic mouse models and germ cell transplantation: two excellent tools for the analysis of genes regulating male fertility
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, Domagkstr 11, 48149, Munster, Germany
    Mol Genet Metab 77:61-7. 2002
    ..The successful culture, cryopreservation, and stable transfection of spermatogonial stem cells combined with the germ cell transplantation technique provide an alternative route for manipulation of the male germ line...
  21. ncbi request reprint Impaired cardiac contraction and relaxation and decreased expression of sarcoplasmic Ca2+-ATPase in mice lacking the CREM gene
    Frank U Müller
    Institute of Pharmacology and Toxicology, University of Munster, Germany
    FASEB J 17:103-5. 2003
    ....
  22. doi request reprint Expression of selected genes escaping from X inactivation in the 41, XX(Y)* mouse model for Klinefelter's syndrome
    Steffi Werler
    Institute of Reproductive and Regenerative Biology, Centre of Reproductive Medicine and Andrology, University Clinics, Muenster, Germany
    Acta Paediatr 100:885-91. 2011
    ..We evaluated the expression of selected X-linked genes in our 41, XX(Y)* male mice to determine whether these genes escape inactivation and whether tissue-specific differences occur...
  23. doi request reprint Testosterone-induced prostate growth is blocked by co- and preadministration of norethisterone enanthate in castrated cynomolgus monkeys
    Joachim Wistuba
    Centre of Reproductive Medicine and Andrology, University Hospital, Munster, Germany joachim wistuba ukmuenster de
    Urol Int 88:358-64. 2012
    ..Examining the role of progestins, we studied the effects of norethisterone (NET) on testosterone undecanoate (TU)-induced prostate growth in castrated macaques...
  24. ncbi request reprint Intrauterine bisphenol A exposure leads to stimulatory effects on Sertoli cell number in rats
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, Domagkstrasse11, 48149 Munster, Germany
    Environ Res 91:95-103. 2003
    ....
  25. ncbi request reprint Transplantation of wild-type spermatogonia leads to complete spermatogenesis in testes of cyclic 3',5'-adenosine monophosphate response element modulator-deficient mice
    Joachim Wistuba
    Institute of Reproductive Medicine of the University, D 48129 Munster, Germany
    Biol Reprod 67:1052-7. 2002
    ..The testicular environment of CREM-deficient mice is not essentially affected and is able to support complete spermatogenesis in the presence of wild-type germ cells...
  26. ncbi request reprint The epithelia of the protrusible tongue of Eurycea longicauda guttolineata (Hoolbrook 1838) (Urodela: Plethodontidae)
    Alfred Opolka
    Klinik und Poliklinik für Allgemeine Chirurgie, University of Munster, Munster, Germany
    Eur J Morphol 41:9-22. 2003
    ..The cells of this gland are stain strongly with alcian blue (pH 1.0) mainly in the basal part of the gland. The results of this are compared to the tongue pad and the lingual gland of Salamandra salamandra and Ambystoma mexicanum...
  27. ncbi request reprint Tooth development in Ambystoma mexicanum: phosphatase activities, calcium accumulation and cell proliferation in the tooth-forming tissues
    Joachim Wistuba
    Institute of Animal Evolution and Ecology, University of Munster, Hüfferstrasse 1, 48149 Munster, Germany
    Ann Anat 185:239-45. 2003
    ....