Stefan Wirtz

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. pmc Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis
    Stefan Wirtz
    Medical Department 1, University of Erlangen Nuremberg, Erlangen, Germany
    Gastroenterology 141:1875-86. 2011
  2. doi request reprint Confocal laser endomicroscopy and narrow-band imaging-aided endoscopy for in vivo imaging of colitis and colon cancer in mice
    Maximilian J Waldner
    Department of Medicine I, University of Erlangen Nuremberg, Erlangen, Germany
    Nat Protoc 6:1471-81. 2011
  3. doi request reprint A variant of Smurf2 protects mice against colitis-associated colon cancer by inducing transforming growth factor β signaling
    Heike Dornhoff
    Department of Medicine, University of Erlangen Nuremberg, Erlangen and Nuremberg, Germany
    Gastroenterology 142:1183-1194.e4. 2012
  4. doi request reprint Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis
    Tamar McHedlidze
    Medical Department 1, Friedrich Alexander University Erlangen Nuremberg, 91054 Erlangen, Germany
    Immunity 39:357-71. 2013
  5. ncbi request reprint TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
    Katharina Gerlach
    Department of Medicine 1, University of Erlangen Nuremberg, Kussmaul Campus for Medical Research, Erlangen, Germany
    Nat Immunol 15:676-86. 2014
  6. pmc The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling
    Christiane Desel
    Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Erlangen, Germany
    PLoS ONE 8:e53531. 2013
  7. doi request reprint Assessment of tumor development and wound healing using endoscopic techniques in mice
    Markus F Neurath
    Medical Clinic 1, Friedrich Alexander University, Erlangen, Germany
    Gastroenterology 139:1837-1843.e1. 2010

Collaborators

Detail Information

Publications7

  1. pmc Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis
    Stefan Wirtz
    Medical Department 1, University of Erlangen Nuremberg, Erlangen, Germany
    Gastroenterology 141:1875-86. 2011
    ..We investigated the roles of IL-27 and IL-35 in chronic inflammation of the intestine...
  2. doi request reprint Confocal laser endomicroscopy and narrow-band imaging-aided endoscopy for in vivo imaging of colitis and colon cancer in mice
    Maximilian J Waldner
    Department of Medicine I, University of Erlangen Nuremberg, Erlangen, Germany
    Nat Protoc 6:1471-81. 2011
    ..Mouse NBI endoscopy and CLE represent reliable and fast high-quality techniques for the endoscopic characterization and molecular imaging of the mucosa in colitis and colon cancer...
  3. doi request reprint A variant of Smurf2 protects mice against colitis-associated colon cancer by inducing transforming growth factor β signaling
    Heike Dornhoff
    Department of Medicine, University of Erlangen Nuremberg, Erlangen and Nuremberg, Germany
    Gastroenterology 142:1183-1194.e4. 2012
    ..We identified a splice variant of Smurf2 (ΔE2Smurf2) and investigated its role in colon carcinogenesis in mice...
  4. doi request reprint Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis
    Tamar McHedlidze
    Medical Department 1, Friedrich Alexander University Erlangen Nuremberg, 91054 Erlangen, Germany
    Immunity 39:357-71. 2013
    ..Our data reveal key immunological networks implicated in hepatic fibrosis and support the concept of modulation of IL-33 bioactivity for therapeutic purposes. ..
  5. ncbi request reprint TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
    Katharina Gerlach
    Department of Medicine 1, University of Erlangen Nuremberg, Kussmaul Campus for Medical Research, Erlangen, Germany
    Nat Immunol 15:676-86. 2014
    ....
  6. pmc The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling
    Christiane Desel
    Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Erlangen, Germany
    PLoS ONE 8:e53531. 2013
    ..Our data suggest that the glycolipid adjuvant TDB triggers Mincle-dependent IL-1 production to induce MyD88-dependent Th1/Th17 responses in vivo...
  7. doi request reprint Assessment of tumor development and wound healing using endoscopic techniques in mice
    Markus F Neurath
    Medical Clinic 1, Friedrich Alexander University, Erlangen, Germany
    Gastroenterology 139:1837-1843.e1. 2010
    ..Finally, mouse endoscopy can help to reduce animal numbers needed to gain significant experimental data...