Research Topics
| Wolfram WindischSummaryAffiliation: University of Freiburg Country: Germany Publications
| Collaborators
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Detail Information
Publications
Respiratory muscle training in restrictive thoracic disease: a randomized controlled trialStephan Budweiser
Center for Pneumology, Donaustauf Hospital, Donaustauf, Germany
Arch Phys Med Rehabil 87:1559-65. 2006..RMT was practicable and safe despite severe respiratory impairment. Further evaluation, including different training intensities and modalities, seems warranted...- Weaning from mechanical ventilation by long-term nasal positive pressure ventilation in two patients with acute respiratory distress syndrome associated with pneumococcal sepsisWolfram Windisch
Department of Pneumology, University Medical Clinic Freiburg, Germany
Respiration 69:464-7. 2002.... - Inspiratory muscle strength in chronic obstructive pulmonary disease depending on disease severityHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Freiburg, Germany
Clin Sci (Lond) 113:243-9. 2007..57; P<0.001). Inspiratory muscle strength, as reliably assessed by TwPmo, decreased with increasing severity of COPD and should be considered as an important factor in rating disease severity and to reflect burden in COPD... - New physiological insights into exercise-induced diaphragmatic fatigueHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Physiol Neurobiol 158:88-96. 2007..In addition, TwPdi is highly correlated to key-measures of ergospirometry, approving the physiological thesis that muscle strength is progressively enhanced and escapes fatiguing failure during high-intensity exercise performance... 
Independence of exercise-induced diaphragmatic fatigue from ventilatory demandsHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Physiol Neurobiol 161:101-7; discussion 108-10. 2008..Therefore, ventilatory demands regulate diaphragmatic force-generation during exercise, whereas DF must be attributed to non-ventilatory controlled feedback mechanisms...- Outcome of patients with stable COPD receiving controlled noninvasive positive pressure ventilation aimed at a maximal reduction of Pa(CO2)Wolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Chest 128:657-62. 2005..Therefore, the 2-year survival and changes in lung function and blood gas levels were analyzed in patients with stable hypercapnic COPD in whom controlled pressure-limited NPPV was titrated to achieve a maximal improvement in Pa(CO2)... - Influence of different trigger techniques on twitch mouth pressure during bilateral anterior magnetic phrenic nerve stimulationWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Chest 128:190-5. 2005.... - Nocturnal non-invasive positive pressure ventilation: physiological effects on spontaneous breathingWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Physiol Neurobiol 150:251-60. 2006.... - Comparison of volume- and pressure-limited NPPV at night: a prospective randomized cross-over trialWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, 79106 Freiburg, Germany
Respir Med 99:52-9. 2005.... - Long-term survival of a patient with congenital central hypoventilation syndrome despite the lack of continuous ventilatory supportWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Freiburg, Germany
Respiration 71:195-8. 2004..CCHS can be managed with NPPV despite mental retardation, even over a long-term period... - The Severe Respiratory Insufficiency (SRI) Questionnaire: a specific measure of health-related quality of life in patients receiving home mechanical ventilationWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
J Clin Epidemiol 56:752-9. 2003..The objective of this study was to develop a specific instrument for measuring health-related quality of life (HRQL) in patients receiving home mechanical ventilation (HMV)... - Evaluation of health-related quality of life using the MOS 36-Item Short-Form Health Status Survey in patients receiving noninvasive positive pressure ventilationWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, 79106, Freiburg, Germany
Intensive Care Med 29:615-21. 2003.... - Post-exercise diaphragm shielding: a novel approach to exercise-induced diaphragmatic fatigueHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Physiol Neurobiol 162:230-7. 2008..This suggests that DF neither reflects impaired diaphragmatic function nor impairs exercise performance; rather it is likely to reflect post-exercise diaphragm shielding... - Diaphragmatic fatigue is counterbalanced during exhaustive long-term exerciseHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Freiburg, Germany
Respir Physiol Neurobiol 172:106-13. 2010..7+/-0.8 kPa vs. 1.9+/-0.6 kPa). In conclusion, diaphragmatic contractility tends to decrease but manifestation of diaphragmatic fatigue is counterbalanced during self-paced long-term exhaustive exercise at maximally tolerated loading... - Biometric approximation of diaphragmatic contractility during sustained hyperpneaHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5 D, 79106, Germany
Respir Physiol Neurobiol 176:90-7. 2011..Thus, reasons other than diaphragmatic fatigue are likely to be responsible for task failure during sustained hyperpnea... - Impairment of respiratory muscle function in pulmonary hypertensionHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, D 79106 Freiburg Germany
Clin Sci (Lond) 114:165-71. 2008..Furthermore, the 6-min walking distance is significantly linked to parameters assessing inspiratory muscle strength... - Noninvasive ventilation in COPD: impact of inspiratory pressure levels on sleep qualityMichael Dreher
Department of Pneumology, University Medical Center, Freiburg, Germany
Chest 140:939-45. 2011..Therefore, the present study assessed the difference in sleep quality during HI-NPPV and LI-NPPV... - Average volume-assured pressure support in obesity hypoventilation: A randomized crossover trialJan Hendrik Storre
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D-79106 Freiburg, Germany
Chest 130:815-21. 2006..AVAPS provided additional benefits on ventilation quality, thus resulting in a more efficient decrease of PtcCO2. However, this did not provide further clinical benefits regarding sleep quality and HRQL... - Controlled twitch mouth pressure reliably predicts twitch esophageal pressureHans Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Physiol Neurobiol 156:276-82. 2007..15kPa (-0.03 to 0.32). TwPmo is an excellent predictor for TwPes when using a fully automated and controlled inspiratory pressure trigger. Thus, measurement of TwPmo could become a standard means assessing inspiratory muscle strength... - High-intensity versus low-intensity non-invasive ventilation in patients with stable hypercapnic COPD: a randomised crossover trialMichael Dreher
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Thorax 65:303-8. 2010..The conventional approach of low-intensity non-invasive positive pressure ventilation (NPPV) produces only minimal physiological and clinical benefits in patients with stable hypercapnic chronic obstructive pulmonary disease (COPD)... 
High-intensity non-invasive positive pressure ventilation for stable hypercapnic COPDWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Germany
Int J Med Sci 6:72-6. 2009....- Transcutaneous PCO2 monitoring during initiation of noninvasive ventilationJan H Storre
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Chest 132:1810-6. 2007..To assess the efficacy of transcutaneous Pco2 (Ptcco2) measurements for monitoring alveolar ventilation in patients requiring noninvasive positive-pressure ventilation (NPPV)... - Characteristics of diaphragmatic fatigue during exhaustive exercise until task failureDavid Johannes Walker
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Physiol Neurobiol 176:14-20. 2011..This confirms previous assumptions postulating that respiratory performance is sustained without further fatigue of the primary inspiratory muscle... - Clinical impact of leak compensation during non-invasive ventilationJan Hendrik Storre
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Med 103:1477-83. 2009..This study aimed to assess the impact of leak compensation capabilities during pressure- and volume-limited non-invasive positive-pressure ventilation (NPPV) in COPD patients... - Proportional assist ventilation improves exercise capacity in patients with obesityMichael Dreher
Department of Pneumology, University Hospital Freiburg, Freiburg, Germany
Respiration 80:106-11. 2010..Exercise capacity is reduced in obese patients due to disadvantageous respiratory mechanics that lead to dyspnea. Proportional assist ventilation (PAV) has the potential to unload resistive and elastic burdens of the ventilatory system... - The Severe Respiratory Insufficiency Questionnaire was valid for COPD patients with severe chronic respiratory failureWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
J Clin Epidemiol 61:848-53. 2008..The present study was aimed at reexamining the internal structure of the SRI specifically for chronic obstructive pulmonary disease (COPD) patients... - Transcutaneous monitoring as a replacement for arterial PCO(2) monitoring during nocturnal non-invasive ventilationJan Hendrik Storre
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Respir Med 105:143-50. 2011..The present study was aimed at investigating the capability of modern PtcCO(2)-monitoring to reliably assess alveolar ventilation during nocturnal NPPV... - Sedation during flexible bronchoscopy in patients with pre-existing respiratory failure: Midazolam versus Midazolam plus AlfentanilMichael Dreher
Department of Pneumology, University Hospital, Freiburg, Germany
Respiration 79:307-14. 2010.... - When should home mechanical ventilation be started in patients with different neuromuscular disorders?Michael Dreher
Department of Pneumology, University Hospital Freiburg, Germany
Respirology 12:749-53. 2007..This study assessed the differences in the physiological parameters of patients with neuromuscular disease commenced on HMV for the treatment of symptomatic chronic hypercapnic respiratory failure... - Non-invasive ventilation applied for recovery from exercise-induced diaphragmatic fatigueHans Joachim Kabitz
Department of Pneumologya, University Hospital Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
Open Respir Med J 2:16-21. 2008.... - Impact of impaired inspiratory muscle strength on dyspnea and walking capacity in sarcoidosisHans-Joachim Kabitz
Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D-79106 Freiburg, Germany
Chest 130:1496-502. 2006.... - Flow-dependent resistance of nasal masks used for non-invasive positive pressure ventilationWolfram Windisch
Department of Pneumology, University Hospital Freiburg, Freiburg, Germany
Respirology 11:471-6. 2006..Therefore, this study was aimed at investigating the resistance of nasal masks used for NPPV... - [Health-related quality of life of patients receiving home mechanical ventilation: the Spanish version of the severe respiratory insufficiency questionnaire]Jose Luis López-Campos
Sección de Neumología y Alergia, Hospital Universitario Puerta del Mar, Cadiz, Espana
Arch Bronconeumol 42:588-93. 2006..Questionnaire for the Spanish population, the first health-related quality of life questionnaire specifically designed for patients receiving home mechanical ventilation... - Prognostic value of mouth occlusion pressure in patients with chronic ventilatory failureStephan Budweiser
Center for Pneumology, Donaustauf Hospital, Ludwigstrasse 68, D 93093, Donaustauf, Germany
Respir Med 101:2343-51. 2007..Mouth occlusion pressure measurement is widely used for assessment of respiratory muscle function, particularly in patients with respiratory failure. However, its predictive value for long-term survival remains largely unexplored... - Health-related quality of life in patients with chronic respiratory failure after long-term mechanical ventilationSara Euteneuer
Krankenhaus Kloster Grafschaft, Schmallenberg, Germany
Respir Med 100:477-86. 2006..Despite severe physical handicaps due to CRF mental health is only mildly compromised... - Predictors of survival in COPD patients with chronic hypercapnic respiratory failure receiving noninvasive home ventilationStephan Budweiser
Center for Pneumology, Donaustauf Hospital, Donaustauf, Germany
Chest 131:1650-8. 2007..Knowledge of prognostic parameters under these conditions is limited but may be clinically helpful and highlight the role of noninvasive ventilation... - PHOX2B mutation-confirmed congenital central hypoventilation syndrome: presentation in adulthoodNick A Antic
Adelaide Institute for Sleep Health, Repatriation General Hospital, Daw Park, South Australia, Australia, and Sleep Disorders Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
Am J Respir Crit Care Med 174:923-7. 2006..Report of these cases should lead to a more rapid identification of CCHS presenting in adulthood...