Ulrich Otto Wenzel

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Renovascular hypertension does not influence repair of glomerular lesions induced by anti-thymocyte glomerulonephritis
    U O Wenzel
    Division of Nephrology, Department of Medicine, and Department of Pathology, University Hospital Hamburg, Germany
    Kidney Int 58:1135-47. 2000
  2. ncbi request reprint A patient with autosomal dominant polycystic kidney and liver disease presenting with urinary tract infection...'Unable to see the wood for the trees'
    Ulrich Wenzel
    Department of Medicine, Division of Nephrology, Martinistr 52, 20246 Hamburg, Germany
    Nephrol Dial Transplant 21:2333-4. 2006
  3. ncbi request reprint Treatment of arterial hypertension in obese patients
    Ulrich O Wenzel
    III Medizinische Klinik, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany
    Contrib Nephrol 151:230-42. 2006
  4. ncbi request reprint Aldosterone antagonists: silver bullet or just sodium excretion and potassium retention?
    U Wenzel
    University Hospital of Hamburg, Department of Medicine, Division of Nephrology, Hamburg, Germany
    Kidney Int 71:374-6. 2007
  5. ncbi request reprint My doctor said I should drink a lot! Recommendations for fluid intake in patients with chronic kidney disease
    Ulrich O Wenzel
    University Hospital of Hamburg Eppendorf, Department of Medicine, Division of Nephrology, Martinistrasse 52, Hamburg, 20246 Germany
    Clin J Am Soc Nephrol 1:344-6. 2006
  6. ncbi request reprint Aldosterone and progression of renal disease
    Ulrich Wenzel
    Department of Medicine, Division of Nephrology, University Hospital of Hamburg, Hamburg, Germany
    Curr Opin Nephrol Hypertens 17:44-50. 2008
  7. ncbi request reprint Management of arterial hypertension in obese patients
    Ulrich O Wenzel
    III Medizinische Klinik, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Curr Hypertens Rep 9:491-7. 2007
  8. ncbi request reprint [Quality of life under antihypertensive therapy: essentially for compliance]
    U Wenzel
    III Medizinische Klinik, Universitatsklinikum, Hamburg Eppendorf
    MMW Fortschr Med 150:30-2. 2008
  9. doi request reprint The angiotensin II type 2 receptor in renal disease
    Ulrich Otto Wenzel
    Department of Medicine, Division of Nephrology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Renin Angiotensin Aldosterone Syst 11:37-41. 2010
  10. ncbi request reprint Massive bleeding after biopsy of a renal allograft
    U Wenzel
    Department of Medicine, Division of Nephrology, University Hospital of Hamburg, Hamburg, Germany
    Kidney Int 69:1101. 2006

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Renovascular hypertension does not influence repair of glomerular lesions induced by anti-thymocyte glomerulonephritis
    U O Wenzel
    Division of Nephrology, Department of Medicine, and Department of Pathology, University Hospital Hamburg, Germany
    Kidney Int 58:1135-47. 2000
    ..To evaluate this effect, we applied a model of glomerulonephritis in rats with two-kidney, one-clip hypertension and studied the effect of hypertension on the healing process of this nephritis...
  2. ncbi request reprint A patient with autosomal dominant polycystic kidney and liver disease presenting with urinary tract infection...'Unable to see the wood for the trees'
    Ulrich Wenzel
    Department of Medicine, Division of Nephrology, Martinistr 52, 20246 Hamburg, Germany
    Nephrol Dial Transplant 21:2333-4. 2006
  3. ncbi request reprint Treatment of arterial hypertension in obese patients
    Ulrich O Wenzel
    III Medizinische Klinik, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany
    Contrib Nephrol 151:230-42. 2006
    ..Sodium retention plays a central role in the development of obesity-related hypertension. Therefore, treatment with an ACE-inhibitors or a diuretic should be considered as first-line antihypertensive drug therapy in obesity-hypertension...
  4. ncbi request reprint Aldosterone antagonists: silver bullet or just sodium excretion and potassium retention?
    U Wenzel
    University Hospital of Hamburg, Department of Medicine, Division of Nephrology, Hamburg, Germany
    Kidney Int 71:374-6. 2007
    ..Innovative approaches are needed to keep patients with chronic kidney disease off dialysis. Blockade of the aldosterone pathway may prove to be such a beneficial therapeutic concept...
  5. ncbi request reprint My doctor said I should drink a lot! Recommendations for fluid intake in patients with chronic kidney disease
    Ulrich O Wenzel
    University Hospital of Hamburg Eppendorf, Department of Medicine, Division of Nephrology, Martinistrasse 52, Hamburg, 20246 Germany
    Clin J Am Soc Nephrol 1:344-6. 2006
  6. ncbi request reprint Aldosterone and progression of renal disease
    Ulrich Wenzel
    Department of Medicine, Division of Nephrology, University Hospital of Hamburg, Hamburg, Germany
    Curr Opin Nephrol Hypertens 17:44-50. 2008
    ..These therapies, however, provide only imperfect protection, since they cannot always prevent endstage renal failure...
  7. ncbi request reprint Management of arterial hypertension in obese patients
    Ulrich O Wenzel
    III Medizinische Klinik, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Curr Hypertens Rep 9:491-7. 2007
    ..Therefore, an ACE inhibitor or diuretic should be considered as first-line antihypertensive drug therapy in obesity-hypertension...
  8. ncbi request reprint [Quality of life under antihypertensive therapy: essentially for compliance]
    U Wenzel
    III Medizinische Klinik, Universitatsklinikum, Hamburg Eppendorf
    MMW Fortschr Med 150:30-2. 2008
  9. doi request reprint The angiotensin II type 2 receptor in renal disease
    Ulrich Otto Wenzel
    Department of Medicine, Division of Nephrology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Renin Angiotensin Aldosterone Syst 11:37-41. 2010
    ..However, further research is needed to explore the question whether AT(2) receptor stimulation may represent a new therapeutic strategy for the treatment of chronic kidney disease...
  10. ncbi request reprint Massive bleeding after biopsy of a renal allograft
    U Wenzel
    Department of Medicine, Division of Nephrology, University Hospital of Hamburg, Hamburg, Germany
    Kidney Int 69:1101. 2006
  11. ncbi request reprint Beneficial and adverse renal and vascular effects of the vasopeptidase inhibitor omapatrilat in renovascular hypertensive rats
    Ulrich O Wenzel
    University Hospital of Hamburg Eppendorf, Department of Medicine, Division of Nephrology, Pav 61, Martinistrasse 52, D 20246 Hamburg, Germany
    Nephrol Dial Transplant 18:2005-13. 2003
    ....
  12. ncbi request reprint [The treatment of arterial hypertension. An inquiry among doctors in general practice]
    U Wenzel
    Abteilung für Nephrologie Osteologie, Klinik und Poliklinik für Innere Medizin, Universitatsklinikum Hamburg Eppendorf, Hamburg
    Dtsch Med Wochenschr 126:1454-9. 2001
    ..There are many drugs used in the treatment of hypertension. National and international expert committees regularly publish recommendations for antihypertensive treatment. It is not known how doctors in general practive treat hypertension...
  13. ncbi request reprint Chronic anti-Thy-1 nephritis is aggravated in the nonclipped but not in the clipped kidney of Goldblatt hypertensive rats
    Ulrich O Wenzel
    Division of Nephrology, Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Kidney Int 61:2119-31. 2002
    ..To test whether a chronic model of the Thy-1 nephritis is more susceptible to high blood pressure, the repetitive hit model was evaluated in rats with 2-kidney, 1-clip Goldblatt hypertension...
  14. ncbi request reprint Angiotensin II infusion ameliorates the early phase of a mesangioproliferative glomerulonephritis
    Ulrich O Wenzel
    Division of Nephrology, Department of Medicine, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Kidney Int 61:1020-9. 2002
    ..Inhibition of the renin-angiotensin system slows the progression of chronic renal disease...
  15. doi request reprint Aliskiren accumulation in the kidney: no major role for binding to renin or prorenin
    Sascha Lange
    Division of Nephrology, Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Hypertens 31:713-9. 2013
    ..This may be attributable to drug accumulation in the kidney as recently shown in rats and mice. Since aliskiren binds to renin we examined in the present study whether this accumulation depends on the renin content of the kidney...
  16. doi request reprint AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease
    Christoph Fraune
    Div of Nephrology, Dept of Medicine, Universitatsklinikum Hamburg Eppendorf, Martinistraβe 52, 20246 Hamburg, Germany
    Am J Physiol Renal Physiol 303:F1037-48. 2012
    ..These observations underscore the pivotal role of targeting ANG II to reduce renal injury...
  17. ncbi request reprint [48-year-old patient with right sided flank pain and hypertension of recent onset. Secondary hypertension caused by embolic renal infarcts due to dissecting renal artery aneurysms]
    D Ameis
    Zentrum fur Innere Medizin, Medizinische Klinik I, Universitätsklinikum Eppendorf, Martinistrasse 52, 20246 Hamburg
    Internist (Berl) 43:1129-32. 2002
  18. ncbi request reprint [Hypertensive disorders in pregnancy]
    G Wolf
    Medizinische Klinik, Abteilung Nephrologie und Osteologie, Universitatsklinikum Hamburg Eppendorf
    Med Klin (Munich) 96:78-86. 2001
    ..Hypertensive pregnant patients should be treated in tertiary centers with an interdisciplinary approach involving obstetricians, neonatologists, and nephrologists...
  19. ncbi request reprint Angiotensin II induces p27(Kip1) expression in renal tubules in vivo: role of reactive oxygen species
    G Wolf
    Department of Medicine, Division of Nephrology and Osteology, University of Hamburg, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Mol Med (Berl) 79:382-9. 2001
    ....
  20. ncbi request reprint Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II
    F Kirchhoff
    Division of Nephrology, Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Kidney Int 73:643-50. 2008
    ..Our study describes a new model of hypertensive end-organ damage and repair in C57BL/6 mice...
  21. ncbi request reprint Antihypertensive therapy induces compartment-specific chemokine expression and a Th1 immune response in the clipped kidney of Goldblatt hypertensive rats
    O M Steinmetz
    Dept of Medicine, Division of Nephrology, University Hospital of Hamburg Eppendorf, 20246 Hamburg, Germany
    Am J Physiol Renal Physiol 292:F876-87. 2007
    ..These findings suggest that the Th1 chemokines IP10 and Mig as well as their receptor CXCR3 are potential targets for therapeutic interventions in ischemic nephropathy...
  22. ncbi request reprint Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats
    C Krebs
    Division of Nephrology, Department of Medicine, University Hospital of Hamburg, Hamburg, Germany
    Kidney Int 72:725-30. 2007
    ..We propose that renin and the (pro)renin receptor may play a profibrotic role in the clipped kidney of Goldblatt rats treated for hypertension...
  23. ncbi request reprint Telmisartan improves endothelial function in patients with essential hypertension
    Ralf A Benndorf
    Clinical Pharmacology Unit, Institute of Experimental and Clinical Pharmacology, University Medical Center, Hamburg Eppendorf, Germany
    J Cardiovasc Pharmacol 50:367-71. 2007
    ..We therefore investigated whether the new ARB telmisartan improves endothelial function and renal vascular resistance in patients with essential hypertension...
  24. ncbi request reprint The renin-angiotensin system and progression of renal disease: from hemodynamics to cell biology
    Gunter Wolf
    Department of Medicine, Division of Nephrology and Osteology, University of Hamburg, Germany
    Nephron Physiol 93:P3-13. 2003
    ..Finally, clinical implications are suggested based on data from clinical studies. A thorough understanding of the RAS is important to recognize the potential of nephroprotective strategies through inhibition of its components...
  25. ncbi request reprint Angiotensin II and cell cycle regulation
    Gunter Wolf
    Department of Medicine, Division of Nephrology and Osteology, University of Hamburg, University Hospital, Germany
    Hypertension 43:693-8. 2004
    ..We review the various angiotensin II-mediated growth processes and their relationship to events governing cell cycle regulation...
  26. ncbi request reprint Angiotensin II upregulates toll-like receptor 4 on mesangial cells
    Gunter Wolf
    Klinik fur Innere Medizin III, University of Jena, Germany, and Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Am Soc Nephrol 17:1585-93. 2006
    ..g., extracellular matrix components) in addition to microbial products, AngII-mediated upregulation of TLR4 also could be relevant for the development of inflammation in many noninfectious renal diseases...