J M Weitzel

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Testis-specific expression of rat mitochondrial glycerol-3-phosphate dehydrogenase in haploid male germ cells
    Joachim M Weitzel
    Institute of Medical Biochemistry and Molecular Biology, University Hospital Hamburg Eppendorf, D 20246 Hamburg, Germany
    Biol Reprod 68:699-707. 2003
  2. ncbi request reprint Regulation of mitochondrial biogenesis by thyroid hormone
    Joachim M Weitzel
    Institut fur Medizinische Biochemie und Molekularbiologie, Abteilung fur Biochemische Endokrinologie, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany
    Exp Physiol 88:121-8. 2003
  3. ncbi request reprint T3-mediated gene expression is independent of PGC-1alpha
    Anne Wulf
    Institut fur Biochemie und Molekularbiologie I, Zentrum für Experimentelle Medizin, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    Mol Cell Endocrinol 270:57-63. 2007
  4. ncbi request reprint Hepatic gene expression patterns in thyroid hormone-treated hypothyroid rats
    J M Weitzel
    Institute of Medical Biochemistry and Molecular Biology, University Hospital Hamburg Eppendorf, 20246 Hamburg, Germany
    J Mol Endocrinol 31:291-303. 2003
  5. ncbi request reprint Hormonal regulation of multiple promoters of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene: identification of a complex hormone-response element in the ubiquitous promoter B
    J M Weitzel
    Institut fur Medizinische Biochemie und Molekularbiologie, Universitatsklinikum Hamburg Eppendorf, Germany
    Eur J Biochem 268:4095-103. 2001
  6. pmc Two thyroid hormone-mediated gene expression patterns in vivo identified by cDNA expression arrays in rat
    J M Weitzel
    Institut fur Medizinische Biochemie und Molekularbiologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Nucleic Acids Res 29:5148-55. 2001
  7. pmc Chicken MAR-binding protein ARBP is homologous to rat methyl-CpG-binding protein MeCP2
    J M Weitzel
    Institut fur Physiologische Chemie, Universitats Krankenhaus Eppendorf, Hamburg, Germany
    Mol Cell Biol 17:5656-66. 1997
  8. ncbi request reprint Germ cell nuclear factor relieves cAMP-response element modulator tau-mediated activation of the testis-specific promoter of human mitochondrial glycerol-3-phosphate dehydrogenase
    Mirjana Rajkovic
    Institut fur Biochemie und Molekularbiologie, Zentrum für Experimentelle Medizin, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    J Biol Chem 279:52493-9. 2004
  9. doi request reprint T3-mediated expression of PGC-1alpha via a far upstream located thyroid hormone response element
    Anne Wulf
    Zentrum für Experimentelle Medizin, Institut fur Biochemie und Molekularbiologie I, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    Mol Cell Endocrinol 287:90-5. 2008
  10. doi request reprint The role of thyroid hormone receptor DNA binding in negative thyroid hormone-mediated gene transcription
    Anne Wulf
    Zentrum für Experimentelle Medizin, Institut fur Biochemie und Molekularbiologie I, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    J Mol Endocrinol 41:25-34. 2008

Collaborators

  • Richard Ivell
  • R Middendorff
  • Anne Wulf
  • Angelika Harneit
  • Marianne G Wetzel
  • Meike Kröger
  • Maxim Kebenko
  • Mirjana Rajkovic
  • Jennifer Merz
  • Hans J Seitz
  • Danijel Frkovic
  • Sebastian Damerow

Detail Information

Publications10

  1. ncbi request reprint Testis-specific expression of rat mitochondrial glycerol-3-phosphate dehydrogenase in haploid male germ cells
    Joachim M Weitzel
    Institute of Medical Biochemistry and Molecular Biology, University Hospital Hamburg Eppendorf, D 20246 Hamburg, Germany
    Biol Reprod 68:699-707. 2003
    ..Our results indicate that rat mGPDH is expressed by a testis-specific promoter from haploid male germ cells in a stage-specific manner...
  2. ncbi request reprint Regulation of mitochondrial biogenesis by thyroid hormone
    Joachim M Weitzel
    Institut fur Medizinische Biochemie und Molekularbiologie, Abteilung fur Biochemische Endokrinologie, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany
    Exp Physiol 88:121-8. 2003
    ....
  3. ncbi request reprint T3-mediated gene expression is independent of PGC-1alpha
    Anne Wulf
    Institut fur Biochemie und Molekularbiologie I, Zentrum für Experimentelle Medizin, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    Mol Cell Endocrinol 270:57-63. 2007
    ..Expression of T3-target genes was not changed upon knock-down of PGC-1alpha. Our data indicate that complex T3-mediated gene expression patterns are maintained independently of PGC-1alpha activation...
  4. ncbi request reprint Hepatic gene expression patterns in thyroid hormone-treated hypothyroid rats
    J M Weitzel
    Institute of Medical Biochemistry and Molecular Biology, University Hospital Hamburg Eppendorf, 20246 Hamburg, Germany
    J Mol Endocrinol 31:291-303. 2003
    ..Regulation of early-induced genes within the first 6 h after administration of T3 on transcript levels correlates with altered protein levels after 24 and 48 h in vivo...
  5. ncbi request reprint Hormonal regulation of multiple promoters of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene: identification of a complex hormone-response element in the ubiquitous promoter B
    J M Weitzel
    Institut fur Medizinische Biochemie und Molekularbiologie, Universitatsklinikum Hamburg Eppendorf, Germany
    Eur J Biochem 268:4095-103. 2001
    ..As it has recently been reported that human mGPDH promoter B is not regulated by tri-iodothyronine, this is the first example of a differentially tri-iodothyronine-regulated orthologous gene promoter in man and rat...
  6. pmc Two thyroid hormone-mediated gene expression patterns in vivo identified by cDNA expression arrays in rat
    J M Weitzel
    Institut fur Medizinische Biochemie und Molekularbiologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Nucleic Acids Res 29:5148-55. 2001
    ....
  7. pmc Chicken MAR-binding protein ARBP is homologous to rat methyl-CpG-binding protein MeCP2
    J M Weitzel
    Institut fur Physiologische Chemie, Universitats Krankenhaus Eppendorf, Hamburg, Germany
    Mol Cell Biol 17:5656-66. 1997
    ..Our results suggest that ARBP/MeCP2 is a multifunctional protein with roles in loop domain organization of chromatin, the structure of pericentromeric heterochromatin, and DNA methylation...
  8. ncbi request reprint Germ cell nuclear factor relieves cAMP-response element modulator tau-mediated activation of the testis-specific promoter of human mitochondrial glycerol-3-phosphate dehydrogenase
    Mirjana Rajkovic
    Institut fur Biochemie und Molekularbiologie, Zentrum für Experimentelle Medizin, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    J Biol Chem 279:52493-9. 2004
    ..Our data suggest a down-regulation of CREMtau-mediated gene expression by GCNF, which might be a general regulation mechanism for several postmeiotically expressed genes with a temporal expression peak during early spermatid development...
  9. doi request reprint T3-mediated expression of PGC-1alpha via a far upstream located thyroid hormone response element
    Anne Wulf
    Zentrum für Experimentelle Medizin, Institut fur Biochemie und Molekularbiologie I, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    Mol Cell Endocrinol 287:90-5. 2008
    ..Since T3 directly regulates PGC-1alpha and PGC-1alpha coactivates liganded TR, we suggest an autoregulatory feed-forward loop of PGC-1alpha activation upon T3 treatment...
  10. doi request reprint The role of thyroid hormone receptor DNA binding in negative thyroid hormone-mediated gene transcription
    Anne Wulf
    Zentrum für Experimentelle Medizin, Institut fur Biochemie und Molekularbiologie I, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    J Mol Endocrinol 41:25-34. 2008
    ..Nevertheless, the DBD is involved in mediating negative gene regulation independent of its capacity to bind DNA...