R Weimer

Summary

Affiliation: University of Giessen
Country: Germany

Publications

  1. ncbi request reprint Switch from cyclosporine A to tacrolimus in renal transplant recipients: impact on Th1, Th2, and monokine responses
    R Weimer
    Department of Internal Medicine, Giessen, Germany
    Hum Immunol 61:884-97. 2000
  2. ncbi request reprint sCD30 and neopterin as risk factors of chronic renal transplant rejection: impact of cyclosporine A, tacrolimus, and mycophenolate mofetil
    R Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplant Proc 37:1776-8. 2005
  3. ncbi request reprint ATG induction therapy: long-term effects on Th1 but not on Th2 responses
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transpl Int 18:226-36. 2005
  4. ncbi request reprint Mycophenolate mofetil-based immunosuppression and cytokine genotypes: effects on monokine secretion and antigen presentation in long-term renal transplant recipients
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplantation 75:2090-9. 2003
  5. doi request reprint Impact of maintenance immunosuppressive regimens--balance between graft protective suppression of immune functions and a near physiological immune response
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Klinikstrasse 36, Giessen, Germany
    Transpl Int 24:596-609. 2011
  6. ncbi request reprint Post-transplant sCD30 and neopterin as predictors of chronic allograft nephropathy: impact of different immunosuppressive regimens
    R Weimer
    Department of Internal Medicine, University Clinic of Giessen and Marburg, Germany
    Am J Transplant 6:1865-74. 2006
  7. ncbi request reprint Immunoglobulin induction therapy in renal transplant recipients: Effects on immunoglobulin and regulatory antibody levels
    A Staak
    Department of Internal Medicine, University Clinic of Giessen and Marburg, Campus Giessen, Giessen, Germany
    Transplant Proc 38:3483-5. 2006
  8. ncbi request reprint Effects of three immunosuppressive regimens on CD4 helper function, B cell monocyte and cytokine responses in renal transplant recipients: 4-month follow-up of a prospective randomized study
    R Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplant Proc 34:2377-8. 2002
  9. doi request reprint One hundred six live kidney donors in a single German transplantation center: renal, physical, and psychological follow-up
    S Albertsmeyer
    Department of Internal Medicine, University Clinic of Giessen and Marburg, Giessen, Germany
    Transplant Proc 42:3992-3. 2010
  10. doi request reprint The risk of polyomavirus-associated graft nephropathy is increased by a combined suppression of CD8 and CD4 cell-dependent immune effects
    F C Renner
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplant Proc 45:1608-10. 2013

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Switch from cyclosporine A to tacrolimus in renal transplant recipients: impact on Th1, Th2, and monokine responses
    R Weimer
    Department of Internal Medicine, Giessen, Germany
    Hum Immunol 61:884-97. 2000
    ..However, enhanced humoral immune responses, Th2 and monokine responses, might have a negative impact on long-term graft function...
  2. ncbi request reprint sCD30 and neopterin as risk factors of chronic renal transplant rejection: impact of cyclosporine A, tacrolimus, and mycophenolate mofetil
    R Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplant Proc 37:1776-8. 2005
    ..001) and neopterin levels (P = .006). Our data indicate that the Th2 activation marker sCD30 provides a risk factor for chronic rejection independent of classical immunological risk factors and may be down-regulated using Tacr treatment...
  3. ncbi request reprint ATG induction therapy: long-term effects on Th1 but not on Th2 responses
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transpl Int 18:226-36. 2005
    ....
  4. ncbi request reprint Mycophenolate mofetil-based immunosuppression and cytokine genotypes: effects on monokine secretion and antigen presentation in long-term renal transplant recipients
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplantation 75:2090-9. 2003
    ..It has been suggested that increased monocyte responses might play a role in chronic allograft rejection...
  5. doi request reprint Impact of maintenance immunosuppressive regimens--balance between graft protective suppression of immune functions and a near physiological immune response
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Klinikstrasse 36, Giessen, Germany
    Transpl Int 24:596-609. 2011
    ....
  6. ncbi request reprint Post-transplant sCD30 and neopterin as predictors of chronic allograft nephropathy: impact of different immunosuppressive regimens
    R Weimer
    Department of Internal Medicine, University Clinic of Giessen and Marburg, Germany
    Am J Transplant 6:1865-74. 2006
    ..Our data suggest that elevated sCD30 and neopterin predict graft deterioration by CAN. Tacr effectively downregulates these responses and might be of advantage in patients with elevated sCD30 or neopterin...
  7. ncbi request reprint Immunoglobulin induction therapy in renal transplant recipients: Effects on immunoglobulin and regulatory antibody levels
    A Staak
    Department of Internal Medicine, University Clinic of Giessen and Marburg, Campus Giessen, Giessen, Germany
    Transplant Proc 38:3483-5. 2006
    ..IVIG induction enhanced immunoregulatory antibody levels early posttransplant, which might provide graft protective effects...
  8. ncbi request reprint Effects of three immunosuppressive regimens on CD4 helper function, B cell monocyte and cytokine responses in renal transplant recipients: 4-month follow-up of a prospective randomized study
    R Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplant Proc 34:2377-8. 2002
  9. doi request reprint One hundred six live kidney donors in a single German transplantation center: renal, physical, and psychological follow-up
    S Albertsmeyer
    Department of Internal Medicine, University Clinic of Giessen and Marburg, Giessen, Germany
    Transplant Proc 42:3992-3. 2010
    ..The objective of this study was to analyze the psychological and physical status as well as renal outcomes of 106 live kidney donors between 1993 and 2003...
  10. doi request reprint The risk of polyomavirus-associated graft nephropathy is increased by a combined suppression of CD8 and CD4 cell-dependent immune effects
    F C Renner
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplant Proc 45:1608-10. 2013
    ..Recipients who progressed from BK viremia to overt PAN showed an additional immunologic defect in CD4(+) T-cell function. Patients on a Tac- plus MMF-based immunosuppression were at higher risk to develop BK viremia...
  11. doi request reprint Impact of pretransplant intravenous immunoglobulin administration on anti-AB0 antibody levels in AB0-incompatible living donor kidney transplantation
    F C Renner
    Department of Internal Medicine, Nephrology and Renal Transplantation, University of Giessen, Germany
    Transplant Proc 42:4003-5. 2010
    ..From March 2007 to July 2010, we performed 14 AB0-incompatible (AB0i) living kidney transplantations using donor blood group-specific immunoadsorption (IA), anti-CD20 monoclonal antibody, and intravenous immunoglobulin (IVIG) pretreatment...
  12. doi request reprint New-onset diabetes mellitus after renal transplantation
    M Eckhard
    3rd Med Dept, University Hospital Giessen and Marburg, Giessen, Germany
    Transplant Proc 41:2544-5. 2009
    ..New-onset diabetes mellitus after organ transplantation (PTDM) significantly impairs patient and organ survival. Published rates of PTDM range from 2% to 54%, depending on the definition...
  13. doi request reprint Postoperative bleeding after AB0-incompatible living donor kidney transplantation
    F C Renner
    Department of Internal Medicine, Nephrology and Renal Transplantation, University of Giessen, Germany
    Transplant Proc 42:4164-6. 2010
    ..Since 2007, we have performed 14 AB0-incompatible (AB0i) living kidney transplantations to increase the number of living kidney transplantations...
  14. ncbi request reprint Tacrolimus intoxication resolved by gastrointestinal bleeding: case report
    F C Renner
    Renal Transplant Unit, University Clinic of Giessen and Marburg, Giessen, Germany
    Transplant Proc 39:522-5. 2007
    ..We concluded that exchange blood transfusions offer an alternative therapeutic approach for patients with severe liver function impairment and tacrolimus intoxication...
  15. ncbi request reprint CD26 expression and enzymatic activity in recipients of kidney allografts
    S Korom
    Department of General and Thoracic Surgery, University Hospital, Justus Liebig University, Giessen, Germany
    Transplant Proc 34:1753-4. 2002
  16. ncbi request reprint Split renal function measured by triphasic helical CT
    Nils Hackstein
    Radiologische Gemeinschaftspraxis am Evangelischen Krankenhaus, Paul Zipp Str 171, 35398 Giessen, Germany
    Eur J Radiol 61:303-9. 2007
    ..To present a method for calculating split renal function solely from routine triphasic helical computed tomography (CT)...
  17. ncbi request reprint Dendritic cell deficiency in the blood of kidney transplant patients on long-term immunosuppression: results of a prospective matched-cohort study
    H Hackstein
    Department for Internal Medicine, Justus Liebig University, Giessen, Germany
    Am J Transplant 5:2945-53. 2005
    ..DC deficiency may have important implications with respect to viral infections and tumor development...
  18. ncbi request reprint Acute rejection of experimental lung allografts: characterization of intravascular mononuclear leukocytes
    Sonja Blöcher
    Laboratory of Experimental Surgery, Department of General and Thoracic Surgery, Justus Liebig University Giessen, University of Giessen Lung Center, Giessen, Germany
    Clin Immunol 124:98-108. 2007
    ..In conclusion, during rejection, monocytes with unusual properties accumulate and T-lymphocytes are activated in lung allograft blood vessels...
  19. ncbi request reprint The effect of ATG on cytokine and cytotoxic T-lymphocyte gene expression in renal allograft recipients during the early post-transplant period
    Tania Simon
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Clin Transplant 17:217-24. 2003
    ..In the present study, we analyzed the effect of ATG-induction therapy on expression of 10 immunologically relevant genes in the early post-transplant period...
  20. doi request reprint Observational support for an immunoregulatory role of CD3+CD4+CD25+IFN-gamma+ blood lymphocytes in kidney transplant recipients with good long-term graft outcome
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Transpl Int 21:646-60. 2008
    ..Our data support an immunoregulatory role of CD3+CD4+CD25+Foxp3+IFN-gamma+ cells in a subgroup of transplant recipients with good graft acceptance...
  21. ncbi request reprint Evaluation of T-cell receptor repertoires in patients with long-term renal allograft survival
    Cristiam M Alvarez
    Grupo de Inmunologia Celular e Inmunogenetica, Universidad de Antioquia, Medellin, Colombia
    Am J Transplant 5:746-56. 2005
    ....