Christian Weimar

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint [Clinical presentation and prognosis of brain stem infarcts. An evaluation of the Stroke Databank of the German Stroke Foundation]
    C Weimar
    Neurologische Klinik der Universität GHS Essen, Hufelandstrasse 55, 45122 Essen
    Nervenarzt 73:166-73. 2002
  2. ncbi request reprint What's new in stroke prevention and treatment
    Christian Weimar
    Department of Neurology, University of Duisburg, EssenHufelandstr 55, 45122 Essen, Germany
    Expert Rev Neurother 6:185-93. 2006
  3. ncbi request reprint Development and validation of a prognostic model to predict recovery following intracerebral hemorrhage
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Neurol 253:788-93. 2006
  4. ncbi request reprint Intravenous thrombolysis in German stroke units before and after regulatory approval of recombinant tissue plasminogen activator
    C Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cerebrovasc Dis 22:429-31. 2006
  5. ncbi request reprint Distribution and outcome of symptomatic stenoses and occlusions in patients with acute cerebral ischemia
    Christian Weimar
    Departments of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Arch Neurol 63:1287-91. 2006
  6. pmc Predictive value of the Essen Stroke Risk Score and Ankle Brachial Index in acute ischaemic stroke patients from 85 German stroke units
    C Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    J Neurol Neurosurg Psychiatry 79:1339-43. 2008
  7. ncbi request reprint Adherence and quality of oral anticoagulation in cerebrovascular disease patients with atrial fibrillation
    C Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur Neurol 60:142-8. 2008
  8. doi request reprint Long-term mortality and risk of stroke after transient ischemic attack: a hospital-based cohort study
    Christian Weimar
    Dept of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:639-44. 2009
  9. doi request reprint Prediction of recurrent stroke and vascular death in patients with transient ischemic attack or nondisabling stroke: a prospective comparison of validated prognostic scores
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Stroke 41:487-93. 2010
  10. doi request reprint Recurrent stroke after cervical artery dissection
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    J Neurol Neurosurg Psychiatry 81:869-73. 2010

Collaborators

Detail Information

Publications53

  1. ncbi request reprint [Clinical presentation and prognosis of brain stem infarcts. An evaluation of the Stroke Databank of the German Stroke Foundation]
    C Weimar
    Neurologische Klinik der Universität GHS Essen, Hufelandstrasse 55, 45122 Essen
    Nervenarzt 73:166-73. 2002
    ..Mortality was 43.5% in patients with combined brainstem infarction. Our study highlights the frequency of small vessel disease as well as the relatively favorable prognosis in isolated brainstem infarction and preserved consciousness...
  2. ncbi request reprint What's new in stroke prevention and treatment
    Christian Weimar
    Department of Neurology, University of Duisburg, EssenHufelandstr 55, 45122 Essen, Germany
    Expert Rev Neurother 6:185-93. 2006
    ..A short critical evaluation at the end of selected reviews should encourage the reader to further reading of studies of interest...
  3. ncbi request reprint Development and validation of a prognostic model to predict recovery following intracerebral hemorrhage
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Neurol 253:788-93. 2006
    ..While several models have been developed to predict mortality following intracerebral hemorrhage (ICH), the functional outcome and its predictors in surviving patients have been poorly investigated so far...
  4. ncbi request reprint Intravenous thrombolysis in German stroke units before and after regulatory approval of recombinant tissue plasminogen activator
    C Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cerebrovasc Dis 22:429-31. 2006
    ..Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) within 3 h after onset of focal cerebral ischemia was approved in Germany in August 2000...
  5. ncbi request reprint Distribution and outcome of symptomatic stenoses and occlusions in patients with acute cerebral ischemia
    Christian Weimar
    Departments of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Arch Neurol 63:1287-91. 2006
    ..To describe the distribution of steno-occlusive disease and the associated rate of recurrence in patients with acute cerebral ischemia...
  6. pmc Predictive value of the Essen Stroke Risk Score and Ankle Brachial Index in acute ischaemic stroke patients from 85 German stroke units
    C Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    J Neurol Neurosurg Psychiatry 79:1339-43. 2008
    ..Risk stratification can contribute to individualised optimal secondary prevention in patients with cerebrovascular disease...
  7. ncbi request reprint Adherence and quality of oral anticoagulation in cerebrovascular disease patients with atrial fibrillation
    C Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur Neurol 60:142-8. 2008
    ..We therefore sought to investigate the prescription patterns at discharge, adherence and quality of OAC in cerebrovascular disease patients with AF...
  8. doi request reprint Long-term mortality and risk of stroke after transient ischemic attack: a hospital-based cohort study
    Christian Weimar
    Dept of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:639-44. 2009
    ..Our aim therefore was to provide a reliable estimate for TIA patients treated in German neurology departments with an acute stroke unit...
  9. doi request reprint Prediction of recurrent stroke and vascular death in patients with transient ischemic attack or nondisabling stroke: a prospective comparison of validated prognostic scores
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Stroke 41:487-93. 2010
    ..We aimed to prospectively compare the predictive accuracy of the Essen Stroke Risk Score, Stroke Prognostic Instrument, Hankey score, and the Life Long After Cerebral ischemia score...
  10. doi request reprint Recurrent stroke after cervical artery dissection
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    J Neurol Neurosurg Psychiatry 81:869-73. 2010
    ..Because only small numbers of patient with CAD have been prospectively documented and followed up, the authors aimed to investigate the prognosis under various prevention regimens...
  11. pmc Development and validation of the Essen Intracerebral Haemorrhage Score
    C Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol Neurosurg Psychiatry 77:601-5. 2006
    ..Nevertheless, outcome is favourable in about 30% of patients. Only one model for the prediction of favourable outcome has been validated so far...
  12. doi request reprint Recurrent stroke after lobar and deep intracerebral hemorrhage: a hospital-based cohort study
    C Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cerebrovasc Dis 32:283-8. 2011
    ..We therefore aimed to assess the patient characteristics and prognosis after deep and lobar ICH in a well-characterized, multicenter, hospital-based cohort...
  13. ncbi request reprint Complications following acute ischemic stroke
    Christian Weimar
    Department of Neurology, University of Essen, Essen, Germany
    Eur Neurol 48:133-40. 2002
    ..This study provides representative data on onset and severity of early neurological and medical complications as well as possible predictors for early recurrent cerebral ischemia following acute ischemic stroke...
  14. ncbi request reprint Etiology, duration, and prognosis of transient ischemic attacks: an analysis from the German Stroke Data Bank
    Christian Weimar
    Department of Neurology, University of Essen, Essen, Germany
    Arch Neurol 59:1584-8. 2002
    ..A transient ischemic attack (TIA) has been arbitrarily defined as a focal cerebral ischemic deficit lasting less than 24 hours...
  15. ncbi request reprint Central poststroke pain in a consecutive cohort of stroke patients
    Christian Weimar
    Department of Neurology, University of Essen, Germany
    Cerebrovasc Dis 14:261-3. 2002
  16. ncbi request reprint [Diagnosis related groups in stroke treatment. An analysis from the stroke data bank of the German Stroke Foundation]
    C Weimar
    Neurologische Klinik, Universitat Essen
    Dtsch Med Wochenschr 127:1627-32. 2002
    ..The upcoming introduction of diagnosis related groups (DRG) as an exclusive base for future calculation of hospital proceeds in Germany requires a thorough analysis of cost data for various diseases...
  17. ncbi request reprint Management patterns and health care use after intracerebral hemorrhage. a cost-of-illness study from a societal perspective in Germany
    Christian Weimar
    Department of Neurology, University of Essen, Germany
    Cerebrovasc Dis 15:29-36. 2003
    ..The aims of this study are to describe the management patterns, cost of treatment and overall resource utilization after intracerebral hemorrhage (ICH) as well as the major differences to ischemic stroke (IS)...
  18. ncbi request reprint Predicting functional outcome and survival after acute ischemic stroke
    Christian Weimar
    Department of Neurology, University of Essen, Hufelandstr 55, Germany
    J Neurol 249:888-95. 2002
    ..We therefore developed prognostic models for functional dependence and death after 100 days in a large cohort of stroke patients...
  19. ncbi request reprint [Treatment of ischemic stroke in 14 neurologic stroke units. An evaluation of the stroke databank of the German Stroke Aid Foundation]
    C Weimar
    Neurologische Klinik der Universität GHS Essen, Hufelandstrasse 55, 45122 Essen
    Nervenarzt 73:342-8. 2002
    ..2% of the patients regained functional independence. This study demonstrates the relatively favorable prognosis of patients in German stroke units as well as the low standardization of diagnostic work-up and treatment strategies...
  20. ncbi request reprint Neurologic worsening during the acute phase of ischemic stroke
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Arch Neurol 62:393-7. 2005
    ..Although capacities for intensive monitoring of patients with stroke are still limited, patients at risk for early neurologic worsening are poorly defined...
  21. ncbi request reprint Telmisartan on top of antihypertensive treatment does not prevent progression of cerebral white matter lesions in the prevention regimen for effectively avoiding second strokes (PRoFESS) MRI substudy
    Ralph Weber
    Department of Neurology, University Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Stroke 43:2336-42. 2012
    ..We investigated whether telmisartan prevents WML progression in the imaging substudy of the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial...
  22. doi request reprint The Essen stroke risk score predicts recurrent cardiovascular events: a validation within the REduction of Atherothrombosis for Continued Health (REACH) registry
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Stroke 40:350-4. 2009
    ..We aimed to validate the ESRS in a large cohort of outpatients with previous transient ischemic attack or stroke from the REduction of Atherothrombosis for Continued Health (REACH) Registry...
  23. doi request reprint Elevated levels of high-sensitivity C-reactive protein are associated with mild cognitive impairment and its subtypes: results of a population-based case-control study
    Martha Dlugaj
    Department of Neurology, University Hospital of Essen, University of Duisburg Essen, Essen, Germany
    J Alzheimers Dis 28:503-14. 2012
    ..These findings suggest that inflammation plays an important role in the development and presence of cognitive impairment...
  24. doi request reprint Prognosis after cryptogenic cerebral ischemia in patients with coagulopathies
    Ralph Weber
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Cerebrovasc Dis 28:611-7. 2009
    ..The goal of this prospective observational multicenter study was to determine the risk of recurrence in cryptogenic stroke patients with either no or defined coagulopathies under various prevention regimens...
  25. ncbi request reprint Adherence to secondary stroke prevention strategies--results from the German Stroke Data Bank
    Gerhard F Hamann
    Department of Neurology, Ludwig Maximilian University, Klinikum Grosshadern, Munich, Germany
    Cerebrovasc Dis 15:282-8. 2003
    ..The highest adherence rate is noticed for aspirin and oral anticoagulation. After one year, very few patients stopped taking stroke preventive medication...
  26. doi request reprint Predicting recovery after intracerebral hemorrhage--an external validation in patients from controlled clinical trials
    Christian Weimar
    Dept of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:464-9. 2009
    ..Here, we demonstrate the applicability of our models in an independent sample of ICH patients from controlled clinical trials...
  27. ncbi request reprint Assessment of functioning and disability after ischemic stroke
    Christian Weimar
    Department of Neurology, University of Essen, Essen, Germany
    Stroke 33:2053-9. 2002
    ..Functioning and disability after ischemic stroke are clinically meaningful and of major relevance to patients. Despite many instruments available to assess these outcomes, little is known about their interrelation and predictive factors...
  28. doi request reprint Vascular risk prediction in ischemic stroke patients undergoing in-patient rehabilitation - insights from the investigation of patients with ischemic stroke in neurologic rehabilitation (INSIGHT) registry
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Int J Stroke 8:503-9. 2013
    ..Quantification of risk in this setting may help to tailor therapy, increase physician awareness and patient compliance and thus to reduce recurrent vascular events...
  29. doi request reprint Discontinuation of antiplatelet study medication and risk of recurrent stroke and cardiovascular events: results from the PRoFESS study
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cerebrovasc Dis 35:538-43. 2013
    ....
  30. pmc Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy
    Ralph Weber
    Department of Neurology, University Duisburg Essen, Essen, Germany
    Stroke 43:350-5. 2012
    ..We assessed whether patients with recent noncardioembolic stroke and SBI detected on MRI are at increased risk for recurrent stroke, other cardiovascular events, and mortality...
  31. doi request reprint Intima-media thickness predicts stroke risk in the Heinz Nixdorf Recall study in association with vascular risk factors, age and gender
    Dirk M Hermann
    Department of Neurology, University Hospital Essen, Hufelandstr 55, D 45122 Essen, Germany
    Atherosclerosis 224:84-9. 2012
    ..The intima-media thickness of the common carotid artery (CIMT) is a non-invasively accessible marker of atherosclerosis, which can be used for risk evaluation...
  32. pmc Cognitive function after transapical aortic valve implantation: a single-centre study with 3-month follow-up
    Stephan C Knipp
    Department of Thoracic and Cardiovascular Surgery, West German Heart Center Essen, Essen, Germany
    Interact Cardiovasc Thorac Surg 16:116-22. 2013
    ..In this study, we prospectively examined neurological and cognitive outcomes in patients undergoing transapical (TA) and surgical aortic valve replacement (AVR)...
  33. pmc Microalbuminuria indicates long-term vascular risk in patients after acute stroke undergoing in-patient rehabilitation
    Dirk Sander
    Department of Neurology, Benedictus Krankenhaus Tutzing and Feldafing, Abteilung fur Neurologie, Dr, Appelhans Weg 6, Feldafing, 82360, Germany
    BMC Neurol 12:102. 2012
    ..We therefore aimed to examine MAU as an indicator of risk and predictor of vascular events in a prospective study...
  34. doi request reprint Medical prevention of stroke and stroke recurrence in patients with TIA and minor stroke
    Ralph Weber
    University Duisburg Essen, Department of Neurology and Stroke Center, Hufeland Street 55, 45122 Essen, Germany
    Expert Opin Pharmacother 10:1883-94. 2009
    ..Secondary stroke prevention after transient ischemic stroke (TIA) or minor stroke is of major importance in order to avoid recurrent cerebrovascular events and decrease morbidity and mortality...
  35. ncbi request reprint Improving patient selection for clinical acute stroke trials
    Christian Weimar
    Department of Neurology, University of Essen, Essen, Germany
    Cerebrovasc Dis 21:386-92. 2006
    ..To optimize patient inclusion criteria for clinical acute stroke trials...
  36. ncbi request reprint Thrombolysis in stroke despite contraindications or warnings?
    Benedikt Frank
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Stroke 44:727-33. 2013
    ..We examined outcomes from alteplase-treated versus untreated patients, registered in a trials archive, according to presence or absence of specified contraindications and warnings...
  37. ncbi request reprint Systemic risk score evaluation in ischemic stroke patients (SCALA): a prospective cross sectional study in 85 German stroke units
    Christian Weimar
    Dept of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    J Neurol 254:1562-8. 2007
    ..hospitalized with TIA/IS to stratify the risk of recurrent stroke according to the Essen Stroke Risk Score (ESRS) and of future cardiovascular events according to the ankle brachial index (ABI) as a marker of generalized atherosclerosis..
  38. doi request reprint Prevalence of mild cognitive impairment and its subtypes in the Heinz Nixdorf Recall study cohort
    Martha Dlugaj
    Department of Neurology, University Hospital Essen, Essen, Germany
    Dement Geriatr Cogn Disord 30:362-73. 2010
    ..We investigated the prevalence of mild cognitive impairment (MCI) and its subtypes according to the original (MCI-original) and modified (MCI-modified; neglecting cognitive complaints) Petersen criteria...
  39. ncbi request reprint Antithrombotic medication for stroke prevention
    Christian Weimar
    Department of Neurology and Stroke Center, University Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Expert Rev Cardiovasc Ther 7:1245-54. 2009
    ..For secondary stroke prevention in patients with atrial fibrillation, oral anticoagulation is more effective than aspirin or the combination of aspirin and clopidogrel...
  40. doi request reprint Subclinical coronary atherosclerosis predicts cardiovascular risk in different stages of hypertension: result of the Heinz Nixdorf Recall Study
    Raimund Erbel
    Department of Cardiology, University Clinic Essen, Essen, Germany
    Hypertension 59:44-53. 2012
    ..This marker of target-organ damage might be included, when lifestyle modification and pharmacotherapeutic effects in prehypertensive individuals are tested to avoid exposure to risk and increase benefit...
  41. ncbi request reprint Sleep-disordered breathing, sleep quality, and mild cognitive impairment in the general population
    Martha Dlugaj
    Department of Neurology, University Hospital of Essen, University of Duisburg Essen, Essen, Germany
    J Alzheimers Dis 41:479-97. 2014
    ....
  42. doi request reprint Ankle-brachial index predicts stroke in the general population in addition to classical risk factors
    Janine Gronewold
    Department of Neurology, University Hospital, University of Duisburg Essen, Hufelandstr 55, D 45122 Essen, Germany Electronic address
    Atherosclerosis 233:545-50. 2014
    ..Herein, we investigated the value of the ankle-brachial index (ABI), a simple non-invasive marker of atherosclerosis, as stroke predictor in addition to established risk factors that are part of the Framingham risk score (FRS)...
  43. doi request reprint International normalised ratio normalisation in patients with coumarin-related intracranial haemorrhages--the INCH trial: a randomised controlled multicentre trial to compare safety and preliminary efficacy of fresh frozen plasma and prothrombin complex--
    Thorsten Steiner
    Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany
    Int J Stroke 6:271-7. 2011
    ..of the international normalized ratio? How feasible is it to apply either of these treatments in an acute situation? What is the safety profile of each of these substances? Is there a difference in haematoma growth and clinical outcome?..
  44. doi request reprint Prevention of cardioembolic stroke in patients with atrial fibrillation
    Ralph Weber
    Department of Neurology and Stroke Center, University Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Expert Rev Cardiovasc Ther 8:1405-15. 2010
    ..Interventional therapies such as percutaneous closure of the left atrial appendage or radiofrequency catheter ablation have not yet been proven to decrease the stroke risk in patients with AF...
  45. ncbi request reprint Patent foramen ovale: paradoxical connection to migraine and stroke
    Hans Christoph Diener
    Department of Neurology, University of Duisburg Essen, Germany
    Curr Opin Neurol 18:299-304. 2005
    ..In this article we aim to elucidate the relationship between patent foramen ovale, cryptogenic stroke and migraine...
  46. ncbi request reprint Patent foramen ovale, migraine and stroke: no reason to intervene
    Hans Christoph Diener
    Department of Neurology, University Duisburg Essen, Germany
    Nat Clin Pract Cardiovasc Med 3:176-7. 2006
  47. ncbi request reprint Stroke: a new CHANCE for combination antiplatelet therapy?
    Hans Christoph Diener
    Department of Neurology and Stroke Centre, University Duisburg Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Nat Rev Neurol 9:549-50. 2013
    ..A new study in Chinese patients suggests that this risk is reduced following treatment with clopidogrel plus aspirin compared with aspirin alone. However, whether the findings can be extrapolated to other populations remains unclear...
  48. doi request reprint Antiplatelet therapy in secondary stroke prevention--state of the art
    Hans Christoph Diener
    Department of Neurology and Stroke Center, University Duisburg Essen, Essen, Germany
    J Cell Mol Med 14:2552-60. 2010
    ..For secondary stroke prevention in patients with atrial fibrillation, oral anticoagulation is more effective than aspirin or the combination of aspirin and clopidogrel...
  49. doi request reprint Preventing cardioembolic stroke in atrial fibrillation with dabigatran
    Christian Weimar
    Department of Neurology and Stroke Unit, University of Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany
    Curr Neurol Neurosci Rep 12:17-23. 2012
    ..The Hemoclot (Hyphen BioMed, Mason, OH) test to measure dabigatran serum concentration is commercially available, but presence of the drug may also be detected using the activated partial thromboplastin time or thrombin time...
  50. doi request reprint Migraine and stroke
    Zaza Katsarava
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Neurol Sci 299:42-4. 2010
    ..For many years, migraine and cerebral ischemic stroke have been linked together. The association between these two diseases is multidimensional and rather complex...
  51. doi request reprint Extent of hypoattenuation on CT angiography source images in basilar artery occlusion: prognostic value in the Basilar Artery International Cooperation Study
    Volker Puetz
    University of Technology Dresden, Dresden University Stroke Center, Department of Neurology, Fetscherstr 74, 01307 Dresden, Germany
    Stroke 42:3454-9. 2011
    ..We hypothesized that pc-ASPECTS applied to CT angiography source images predicts functional outcome of patients in the Basilar Artery International Cooperation Study (BASICS)...
  52. doi request reprint Periprocedural aspects in mechanical recanalization for acute stroke: data from the ENDOSTROKE registry
    Oliver C Singer
    Department of Neurology, Goethe University, Schleusenweg 2 16, 60528, Frankfurt Main, Germany
    Neuroradiology 55:1143-51. 2013
    ..This analysis focuses on preprocedural imaging, patient handling and referral, as well as on different treatment modalities in mechanical recanalization...
  53. ncbi request reprint Intracluster correlation coefficients and reliability of randomized multicenter stroke trials within VISTA
    Benedikt Frank
    Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Western Infirmary, UK Department of Neurology, University of Duisburg Essen, Essen, Germany
    Int J Stroke 9:602-6. 2014
    ..ICCs indicate the proportion of data variability that is explained by defined levels of clustering...