Research Topics
Genomes and Genes | S K WeilandSummaryAffiliation: University of Ulm Country: Germany Publications
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Publications
Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methodsS K Weiland
Dept of Epidemiology, University of Ulm, Helmholzstr 22, 89081, Ulm, Germany
Eur Respir J 24:406-12. 2004..The majority of centres are in countries that participated in International Study of Asthma and Allergies in Childhood Phase I and reflect almost the full range of the observed variability in Phase I prevalence rates...
Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in childrenS K Weiland
Department of Epidemiology, University of Ulm, Ulm, Germany
Occup Environ Med 61:609-15. 2004..To investigate the association between climate and atopic diseases using worldwide data from 146 centres of the International Study of Asthma and Allergies in Childhood (ISAAC)...
International variations in associations of allergic markers and diseases in children: ISAAC Phase TwoG Weinmayr
Institute of Epidemiology, Ulm University, Helmholtzstrasse 22, Ulm, Germany
Allergy 65:766-75. 2010..We analysed the association between SPTs, total and allergen-specific IgE and their relationships to allergic symptoms in centres with diverse living conditions...
A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2J Genuneit
Institute of Epidemiology, Ulm University, Ulm, Germany
Clin Exp Allergy 39:1875-88. 2009..We investigated their associations with wheeze and allergy in a case-control sample from Phase 2 of the International Study of Asthma and Allergies in Childhood...
Effect of diet on asthma and allergic sensitisation in the International Study on Allergies and Asthma in Childhood (ISAAC) Phase TwoGabriele Nagel
Institute of Epidemiology, Ulm University, Ulm, Germany
Thorax 65:516-22. 2010..A study was undertaken to assess the association between dietary factors, asthma and allergy in a large international study including objective measurements of atopy...
International variations in bronchial responsiveness in children: findings from ISAAC phase twoGisela Büchele
Institute of Epidemiology, University of Ulm, Ulm, Germany
Pediatr Pulmonol 45:796-806. 2010..Bronchial responsiveness is an objectively measurable trait related to asthma. Its prevalence and association with asthma symptoms among children in many countries are unknown...
Effect of breastfeeding on asthma, lung function and bronchial hyperreactivity in ISAAC Phase IIG Nagel
Institute of Epidemiology, Ulm University, Ulm, Germany
Eur Respir J 33:993-1002. 2009..These findings may explain some of the controversy regarding breastfeeding, since the direction of the association with breastfeeding depends on the predominating wheeze phenotype (e.g. atopic, nonatopic)...
The relation of markers of fetal growth with asthma, allergies and serum immunoglobulin E levels in children at age 5-7 yearsG Bolte
Department of Epidemiology, University of Ulm, Ulm, Germany
Clin Exp Allergy 34:381-8. 2004..It has been suggested that fetal growth and maturation have an impact on the development of allergic diseases later in life...
Secular changes of anthropometric measures for the past 30 years in South-West GermanyG Nagel
Institute of Epidemiology, Ulm University, Ulm, Germany
Eur J Clin Nutr 63:1440-3. 2009..Body fat among 6- to 9-year-old children increased dramatically within 30 years. Moreover, our data suggest substantial changes in body composition among normal-weight children towards an increased body fat mass...
International variation in prevalence of rhinitis and its relationship with sensitisation to perennial and seasonal allergensG Weinmayr
Institute of Epidemiology, Ulm University, Helmholtzstr 22, D 89075 Ulm, Germany
Eur Respir J 32:1250-61. 2008..Atopy seems to be only marginally relevant for rhinitis without conjunctivitis, which seems mainly to reflect nonatopic rhinitis...
Atopic sensitization and the international variation of asthma symptom prevalence in childrenGudrun Weinmayr
Institute of Epidemiology, Ulm University, Helmholtzstrasse 22, D 89075 Ulm, Germany
Am J Respir Crit Care Med 176:565-74. 2007..Atopic sensitization has long been known to be related to asthma in children, but its role in determining asthma prevalence remains to be elucidated further...
Obesity and incidence of cancer: a large cohort study of over 145,000 adults in AustriaK Rapp
Department of Epidemiology, University of Ulm, Helmholtzstrasse 22, 89081 Ulm, Germany
Br J Cancer 93:1062-7. 2005..56 for BMI> or =35 kg m(-2)). Incidence of breast cancer was positively associated with high BMI only after age 65 years. These findings provide further evidence that overweight is associated with the incidence of several types of cancer...
Smoking and the incidence of asthma during adolescence: results of a large cohort study in GermanyJ Genuneit
Department of Epidemiology, University of Ulm, Helmholtzstr 22, D-89081 Ulm, Germany
Thorax 61:572-8. 2006..Relatively lower plasma levels of alpha(1)-antitrypsin, although well above currently accepted thresholds, may increase susceptibility to respiratory disease among atopic smokers...
Fatty acids in serum cholesteryl esters in relation to asthma and lung function in childrenG Bolte
Department of Epidemiology, University of Ulm, Ulm, Germany
Clin Exp Allergy 36:293-302. 2006..Elevated arachidonic acid levels in children with asthma may be because of a disturbed balance in the metabolism of n-6 PUFA or may be secondary to inflammation in these patients...
Satellite symposium: Asthma in the World. Asthma among children in EuropeS K Weiland
Department of Epidemiology, University of Ulm, Ulm, Germany
Allergol Immunopathol (Madr) 32:100. 2004
Fasting blood glucose and cancer risk in a cohort of more than 140,000 adults in AustriaK Rapp
Department of Epidemiology, University of Ulm, Ulm, Germany
Diabetologia 49:945-52. 2006..We investigated relations between fasting blood glucose and the incidence of cancer...
Type of kindergarten and other potential determinants of overweight in pre-school childrenK Rapp
Department of Epidemiology, University of Ulm, Heimholtzstrasse 22, D 89081 Ulm, Germany
Public Health Nutr 8:642-9. 2005..The study aimed to assess the relationship of various types of kindergarten differing in length of care and food availability with the development of overweight in pre-school children...
Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in ChildhoodBengt Bjorksten
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Pediatr Allergy Immunol 19:110-24. 2008..The increases were more pronounced in the older age group, suggesting that environmental influences on the development of allergy may not be limited to early childhood...
Association between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sampleM Kabesch
University Children s Hospital Munich, Munich, Germany
Clin Exp Allergy 34:340-5. 2004..Recently it has been suggested that a proteinase inhibitor gene, SPINK5, which is located on chromosome 5q31, may play a role in the pathogenesis of atopic diseases...
Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programmeRichard Beasley
Medical Research Institute of New Zealand, Wellington, New Zealand
Lancet 372:1039-48. 2008..We studied 6-7-year-old children from Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) programme to investigate the association between paracetamol consumption and asthma...
Symptoms of asthma and the home environment. The ISAAC I and III cross-sectional surveys in Münster, GermanyT Behrens
Institute of Epidemiology and Social Medicine, , , Germany
Int Arch Allergy Immunol 137:53-61. 2005..The effect of allergy-related change in behavior and the results observed concerning the ownership of pets at different ages underline the need of establishing a precise temporal relationship between disease and exposure...
Alpha1 antitrypsin and the prevalence and severity of asthmaO S von Ehrenstein
University Children's Hospital, Munich, Germany
Arch Dis Child 89:230-1. 2004..Asthmatics with low levels of alpha1-AT were particularly prone to develop airway hyperresponsiveness and reduced lung function...
Are asthma and allergies in children and adolescents increasing? Results from ISAAC phase I and phase III surveys in Münster, GermanyW Maziak
Institute of Epidemiology and Social Medicine, University of Munster, Germany
Allergy 58:572-9. 2003..To assess time trends in symptoms of asthma, allergic rhinitis, and atopic eczema among children in Münster, Germany...
Urban traffic and pollutant exposure related to respiratory outcomes and atopy in a large sample of childrenT Nicolai
University Children s Hospital, Munich, Germany
Eur Respir J 21:956-63. 2003..However, effects of socioeconomic factors associated with living close to busy roads cannot be ruled out...
The management of childhood asthma in the communityW Maziak
Institute of Epidemiology and Social Medicine, , , Germany
Eur Respir J 20:1476-82. 2002..Further efforts to improve the diagnosis and treatment of childhood asthma are needed. These should aim to increase awareness of the chronic nature of asthma and the need for treatment according to current guidelines...
Cancer and non-cancer mortality in a cohort of recent entrants (1981-2000) to the German rubber industryD Taeger
Occup Environ Med 64:560-1. 2007
Leisure time activity and new onset of wheezing during adolescenceC Vogelberg
University Children s Hospital, Fetscherstr 74, 01307, Dresden, Germany
Eur Respir J 30:672-6. 2007..However, the present data do not allow for determining whether smoking operated as a confounder or as an intermediate factor, i.e. whether physical activities prevented active smoking...
A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseasesM Kabesch
University Children s Hospital, Ludwig Maximilian s University Munich, Munchen, Germany
Allergy 59:520-5. 2004....
Polymorphisms in eosinophil pathway genes, asthma and atopyM Kabesch
University Children s Hospital, Ludwig Maximilians University Munich, Munich, Germany
Allergy 62:423-8. 2007....
No increase in the prevalence of asthma, allergies, and atopic sensitisation among children in Germany: 1992-2001I K Zöllner
Department of Epidemiology and Health Reporting, Baden Wuerttemberg State Health Office, Wiederholdstr 15, D 70174 Stuttgart, Germany
Thorax 60:545-8. 2005..The aim of this study was to investigate time trends in the prevalence of asthma and allergic sensitisation among school children in Germany between 1992 and 2001...
Lung function of school children with low levels of alpha1-antitrypsin and tobacco smoke exposureO S von Ehrenstein
University Children's Hospital Munich, Germany
Eur Respir J 19:1099-106. 2002....
Asthma prevalence in adults: good news?S K Weiland
Thorax 59:637-8. 2004
Cancer mortality in German carbon black workers 1976-98J Wellmann
Institute of Epidemiology and Social Medicine, University of Munster, Munster, Germany
Occup Environ Med 63:513-21. 2006..Few studies have investigated cancer risks in carbon black workers and the findings were inconclusive...
Glutathione S transferase deficiency and passive smoking increase childhood asthmaM Kabesch
University Children s Hospital, Ludwig Maxmilians University Munich, Lindwurmstrasse 4, D 80337 Munich, Germany
Thorax 59:569-73. 2004..It has been suggested that the genetically determined deficiency of glutathione S transferase (GST) enzymes involved in the detoxification of environmental tobacco smoke (ETS) components may contribute to the development of asthma...
The cooperation of medical informatics, biometry and epidemiologyR Klar
Methods Inf Med 45:331-5. 2006
Nonatopic asthma is associated with helminth infections and bronchiolitis in poor childrenM U Pereira
Paediatric Pulmonary Research Laboratory, Biomedical Research Institute, Pontifical Catholic University of Rio Grande de Sul, Porto Alegre, Brazil
Eur Respir J 29:1154-60. 2007....
International correlations between indicators of prevalence, hospital admissions and mortality for asthma in childrenH R Anderson
Division of Community Health Sciences, St George s, University of London, UK
Int J Epidemiol 37:573-82. 2008..There are extensive data on the prevalence of childhood asthma world-wide but the relationships between asthma symptom prevalence, mortality and hospital admissions have not been investigated...
STAT1 gene variations, IgE regulation and atopyL A Pinto
University Children s Hospital, Ludwig Maximilian s University Munich, Munich, Germany
Allergy 62:1456-61. 2007....
The use of anti-asthmatic drugs in children: results of a community-based survey in GermanyC Beimfohr
Institute of Epidemiology and Social Medicine, , Domagkstr. 3, , Germany
Pharmacoepidemiol Drug Saf 10:315-21. 2001..Most of the anti-inflammatory drugs used were SCG, which may indicate under-treatment with inhaled steroids...
