Paschal A Oude Weernink

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint Control of cellular phosphatidylinositol 4,5-bisphosphate levels by adhesion signals and rho GTPases in NIH 3T3 fibroblasts involvement of both phosphatidylinositol-4-phosphate 5-kinase and phospholipase C
    P A Weernink
    Institut fur Pharmakologie, Universitatsklinikum Essen, Germany Institut für Medizinische Mikrobiologie und Hygiene, Universitat Mainz, Germany
    Eur J Biochem 267:5237-46. 2000
  2. ncbi request reprint Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42
    Paschal A Oude Weernink
    Institut fur Pharmakologie, Universitatsklinikum Essen, Essen 45122, Germany
    J Biol Chem 279:7840-9. 2004
  3. ncbi request reprint Regulation and cellular roles of phosphoinositide 5-kinases
    Paschal A Oude Weernink
    Institut fur Pharmakologie, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Eur J Pharmacol 500:87-99. 2004
  4. ncbi request reprint Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B
    Sandrine Evellin
    Institut fur Pharmakologie, Universitatsklinikum Essen, D 45122 Essen, Germany
    J Biol Chem 277:16805-13. 2002
  5. ncbi request reprint A role for rho-kinase in rho-controlled phospholipase D stimulation by the m3 muscarinic acetylcholine receptor
    M Schmidt
    Institut fur Pharmakologie, Universitatsklinikum Essen, D 45122 Essen, Germany
    J Biol Chem 274:14648-54. 1999
  6. ncbi request reprint G protein-coupled receptor-induced sensitization of phospholipase C stimulation by receptor tyrosine kinases
    M Schmidt
    Institut fur Pharmakologie, Universitatsklinikum Essen, D 45122 Essen, Germany
    J Biol Chem 275:32603-10. 2000
  7. ncbi request reprint A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase
    M Schmidt
    Institut fur Pharmakologie, Universitatsklinikum Essen, 45122 Essen, Germany
    Nat Cell Biol 3:1020-4. 2001

Collaborators

  • Marianne Schmidt
  • Y Guo
  • C Zhang
  • Paschal A Oude Weernink
  • Karl H Jakobs
  • Sandrine Evellin
  • Jon W Lomasney
  • Frank vom Dorp
  • Karina Tysack
  • Edwin J Webb
  • Jan Nolte
  • Markus Thiel

Detail Information

Publications7

  1. ncbi request reprint Control of cellular phosphatidylinositol 4,5-bisphosphate levels by adhesion signals and rho GTPases in NIH 3T3 fibroblasts involvement of both phosphatidylinositol-4-phosphate 5-kinase and phospholipase C
    P A Weernink
    Institut fur Pharmakologie, Universitatsklinikum Essen, Germany Institut für Medizinische Mikrobiologie und Hygiene, Universitat Mainz, Germany
    Eur J Biochem 267:5237-46. 2000
    ....
  2. ncbi request reprint Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42
    Paschal A Oude Weernink
    Institut fur Pharmakologie, Universitatsklinikum Essen, Essen 45122, Germany
    J Biol Chem 279:7840-9. 2004
    ....
  3. ncbi request reprint Regulation and cellular roles of phosphoinositide 5-kinases
    Paschal A Oude Weernink
    Institut fur Pharmakologie, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Eur J Pharmacol 500:87-99. 2004
    ..Spatially and temporally organized regulation of PIP(2) synthesis by PIP5K enables dynamic and versatile PIP(2) signaling and represents an important link in the execution of cellular tasks by Rho and ARF GTPases...
  4. ncbi request reprint Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B
    Sandrine Evellin
    Institut fur Pharmakologie, Universitatsklinikum Essen, D 45122 Essen, Germany
    J Biol Chem 277:16805-13. 2002
    ....
  5. ncbi request reprint A role for rho-kinase in rho-controlled phospholipase D stimulation by the m3 muscarinic acetylcholine receptor
    M Schmidt
    Institut fur Pharmakologie, Universitatsklinikum Essen, D 45122 Essen, Germany
    J Biol Chem 274:14648-54. 1999
    ..We conclude that Rho-kinase is involved in Rho-dependent PLD stimulation by the G protein-coupled m3 mAChR in HEK-293 cells. Thus, our findings identify Rho-kinase as a novel player in the receptor-controlled PLD signaling pathway...
  6. ncbi request reprint G protein-coupled receptor-induced sensitization of phospholipase C stimulation by receptor tyrosine kinases
    M Schmidt
    Institut fur Pharmakologie, Universitatsklinikum Essen, D 45122 Essen, Germany
    J Biol Chem 275:32603-10. 2000
    ....
  7. ncbi request reprint A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase
    M Schmidt
    Institut fur Pharmakologie, Universitatsklinikum Essen, 45122 Essen, Germany
    Nat Cell Biol 3:1020-4. 2001
    ..We provide evidence that these receptor responses are mediated by a Rap GTPase, specifically Rap2B, activated by a guanine-nucleotide-exchange factor (Epac) regulated by cAMP, and involve the recently identified PLC-epsilon isoform...