Research Topics
Species | S U WeberSummaryAffiliation: University of Bonn Country: Germany Publications
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Detail Information
Publications
A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control studyLutz E Lehmann
University Department of Anaesthesiology and Pain Therapy, Inselspital, CH 3010 Bern, Switzerland
J Transl Med 7:100. 2009..The purpose of the study was to analyze their association with the incidence and outcome of severe sepsis...
Inducibility of the endogenous antibiotic peptide beta-defensin 2 is impaired in patients with severe sepsisMalte Book
Department of Anaesthesiology and Intensive Care Medicine, Rheinische Friedrich Wilhelms University Bonn, Bonn, Germany
Crit Care 11:R19. 2007..This study investigated the basic expression levels and the ex vivo inducibility of hBD2 mRNA in peripheral whole blood cells from patients with severe sepsis in comparison to non-septic critically ill patients and healthy individuals...
[Apoptosis as a pathomechanism in sepsis]S U Weber
Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitatsklinikum Bonn, Rheinische Friedrich Wilhems Universität
Anaesthesist 53:59-65. 2004..Recent reports indicate the relevance of apoptosis in patients with severe sepsis. These results may spawn novel immunomodulatory strategies in the treatment of sepsis...
Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsisStefan U Weber
Department of Anesthesiology and Intensive Care Medicine, University Bonn Medical Center, Sigmund Freud Strasse 25, 53129 Bonn, Germany
Crit Care 12:R128. 2008..This study investigates the gene regulation of pro-apoptotic and anti-apoptotic members of the Bcl-2 family of proteins in patients with early stage severe sepsis...
Hyperbaric oxygen induces apoptosis via a mitochondrial mechanismStefan U Weber
Department of Anesthesiology and Intensive Care Medicine, University of Bonn Medical Center, Sigmund Freud Str 25, 53105 Bonn, Germany
Apoptosis 14:97-107. 2009..Regulation of Fas and Bcl-2 may be regarded as protective measures of the cell in response to hyperbaric oxygen...
Low serum alpha-tocopherol and selenium are associated with accelerated apoptosis in severe sepsisStefan U Weber
Department of Anesthesiology and Intensive Care Medicine, University of Bonn Medical Center, Bonn, Germany
Biofactors 33:107-19. 2008..Accelerated apoptosis in sepsis is associated with low alpha-tocopherol and selenium. The results support the investigation of micronutrient supplementation strategies in severe sepsis...
A single exposure to hyperbaric oxygen increases levels of circulating nucleosomes but does not induce mononuclear cell apoptosis in diversS U Weber
Department of Anesthesiology and Intensive Care Medicine, University of Bonn Medical Center, Bonn, Germany
Undersea Hyperb Med 36:117-25. 2009..mRNA levels of Bcl-2, Bcl-xl and Bax were not altered. In conclusion, while evidence of elevated levels of circulating nucleosomes was found, mononuclear cell apoptosis was not affected by a single exposure to hyperbaric oxygen...
[Traumatic tricuspid valve insufficiency with right-to-left shunt: bridging using extracorporeal venovenous membrane oxygenation]S U Weber
Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53105, Bonn, Deutschland
Anaesthesist 61:41-6. 2012..The patient could be successfully treated by the combination of extracorporeal membrane oxygenation for bridging, interventional ASD occlusion and in the long-term by operative reconstruction of the tricuspid valve...
