Jan M Weber

Summary

Affiliation: University of Duisburg-Essen
Country: Germany

Publications

  1. pmc Control of replication initiation by the Sum1/Rfm1/Hst1 histone deacetylase
    Jan M Weber
    Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, 45117 Essen, Germany
    BMC Mol Biol 9:100. 2008
  2. pmc Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79
    Stefan Ehrentraut
    Abteilung fur Genetik, Zentrum für Medizinische Biotechnologie ZMB, Universitat Duisburg Essen, D 45141 Essen, Germany
    Genes Dev 25:1835-46. 2011
  3. pmc Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange
    Franziska Heise
    Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, Essen, Germany
    Nucleic Acids Res 40:65-74. 2012
  4. pmc Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate
    Stefan Ehrentraut
    Abteilung für Genetik and Abteilung für Bioinformatik, Zentrum für Medizinische Biotechnologie, Universitat Duisburg Essen, D 45117 Essen, Germany
    Proc Natl Acad Sci U S A 107:5522-7. 2010
  5. pmc Design of a minimal silencer for the silent mating-type locus HML of Saccharomyces cerevisiae
    Jan M Weber
    Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, 45117 Essen, Germany
    Nucleic Acids Res 38:7991-8000. 2010

Collaborators

Detail Information

Publications5

  1. pmc Control of replication initiation by the Sum1/Rfm1/Hst1 histone deacetylase
    Jan M Weber
    Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, 45117 Essen, Germany
    BMC Mol Biol 9:100. 2008
    ..Sum1 is part of the Sum1/Rfm1/Hst1 complex that represses meiotic genes during vegetative growth via histone deacetylation by the histone deacetylase (HDAC) Hst1...
  2. pmc Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79
    Stefan Ehrentraut
    Abteilung fur Genetik, Zentrum für Medizinische Biotechnologie ZMB, Universitat Duisburg Essen, D 45141 Essen, Germany
    Genes Dev 25:1835-46. 2011
    ..In summary, the unique folding of this conserved Sir3 AAA(+) domain generates novel surface regions that mediate Sir3-Sir4 and Sir3-nucleosome interactions, both being required for the proper assembly of heterochromatin in living cells...
  3. pmc Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange
    Franziska Heise
    Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, Essen, Germany
    Nucleic Acids Res 40:65-74. 2012
    ....
  4. pmc Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate
    Stefan Ehrentraut
    Abteilung für Genetik and Abteilung für Bioinformatik, Zentrum für Medizinische Biotechnologie, Universitat Duisburg Essen, D 45117 Essen, Germany
    Proc Natl Acad Sci U S A 107:5522-7. 2010
    ..In essence, OAADPR therefore is unavailable for binding to Sir3, preventing SIR propagation...
  5. pmc Design of a minimal silencer for the silent mating-type locus HML of Saccharomyces cerevisiae
    Jan M Weber
    Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, 45117 Essen, Germany
    Nucleic Acids Res 38:7991-8000. 2010
    ..Moreover, deletions of SIR1 and DOT1 lead to complete derepression of the HML-SS ΔI silencer. This fully functional, minimal HML-E silencer will therefore be useful to identify novel factors involved in HML silencing...