P H Warnke

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. ncbi request reprint First experiences with recombinant human bone morphogenetic protein 7 (osteogenic protein 1) in a human case in maxillofacial surgery
    Patrick H Warnke
    Plast Reconstr Surg 111:2471-2. 2003
  2. ncbi request reprint Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Biomaterials 27:3163-7. 2006
  3. ncbi request reprint BMP-2 and bFGF in an irradiated bone model
    Ingo N G Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 36:210-7. 2008
  4. ncbi request reprint Antibacterial essential oils in malodorous cancer patients: clinical observations in 30 patients
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    Phytomedicine 13:463-7. 2006
  5. ncbi request reprint Growth and transplantation of a custom vascularised bone graft in a man
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Lancet 364:766-70. 2004
  6. doi request reprint The battle against multi-resistant strains: Renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 37:392-7. 2009
  7. ncbi request reprint The mechanical integrity of in vivo engineered heterotopic bone
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24 105 Kiel, Germany
    Biomaterials 27:1081-7. 2006
  8. ncbi request reprint Innate immunity in human bone
    P H Warnke
    Dept of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Bone 38:400-8. 2006
  9. ncbi request reprint Intraoral lesions associated with sebaceous nevus syndrome
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    J Cutan Pathol 33:175-80. 2006
  10. ncbi request reprint Repair of a human face by allotransplantation
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, 24105 Kiel, Germany
    Lancet 368:181-3. 2006

Detail Information

Publications49

  1. ncbi request reprint First experiences with recombinant human bone morphogenetic protein 7 (osteogenic protein 1) in a human case in maxillofacial surgery
    Patrick H Warnke
    Plast Reconstr Surg 111:2471-2. 2003
  2. ncbi request reprint Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Biomaterials 27:3163-7. 2006
    ..We describe our and the patient's experiences with this procedure. We give details to the benefits and limitations of this technique as it stands and outline issues that should be addressed in future human clinical trials...
  3. ncbi request reprint BMP-2 and bFGF in an irradiated bone model
    Ingo N G Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 36:210-7. 2008
    ..Bone morphogenetic protein-2 (rhBMP-2) is known to induce bone formation. The aim of this study was to analyze the effect of bFGF and rhBMP-2 in the irradiated mandible...
  4. ncbi request reprint Antibacterial essential oils in malodorous cancer patients: clinical observations in 30 patients
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    Phytomedicine 13:463-7. 2006
    ..The patients experienced great personal relief upon resolution of their malodorous conditions. Quality of life improved significantly with the resulting reintroduction of social contact with friends and relatives...
  5. ncbi request reprint Growth and transplantation of a custom vascularised bone graft in a man
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Lancet 364:766-70. 2004
    ..We aimed to repair an extended mandibular discontinuity defect by growth of a custom bone transplant inside the latissimus dorsi muscle of an adult male patient...
  6. doi request reprint The battle against multi-resistant strains: Renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 37:392-7. 2009
    ..As proven in vitro, essential oils represent a cheap and effective antiseptic topical treatment option even for antibiotic-resistant strains as MRSA and antimycotic-resistant Candida species...
  7. ncbi request reprint The mechanical integrity of in vivo engineered heterotopic bone
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24 105 Kiel, Germany
    Biomaterials 27:1081-7. 2006
    ..This differed significantly from the much lower compression resistance seen in the unadulterated BioOss [0.92 MPa (SD+/-0.04)]. Following this, the in vivo engineered bone has a similar mechanical compression stability as natural bone...
  8. ncbi request reprint Innate immunity in human bone
    P H Warnke
    Dept of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Bone 38:400-8. 2006
    ..We provide the first evidence of a previously unrecognized innate immunological function of bone through the demonstration of the presence of the human beta-defensins hBD-1, -2 and -3 in bone...
  9. ncbi request reprint Intraoral lesions associated with sebaceous nevus syndrome
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    J Cutan Pathol 33:175-80. 2006
    ..Awareness of the potential presence or development of significant intraoral lesions in association with the sebaceous nevus syndrome is important for those involved in the care of patients with this syndrome...
  10. ncbi request reprint Repair of a human face by allotransplantation
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, 24105 Kiel, Germany
    Lancet 368:181-3. 2006
  11. doi request reprint Rapid prototyping: porous titanium alloy scaffolds produced by selective laser melting for bone tissue engineering
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    Tissue Eng Part C Methods 15:115-24. 2009
    ..In summary, the scaffolds are biocompatible, and pore width influences pore overgrowth, resistance to compressive force, and porosity...
  12. doi request reprint Penicillin compared with other advanced broad spectrum antibiotics regarding antibacterial activity against oral pathogens isolated from odontogenic abscesses
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 36:462-7. 2008
    ..The in vitro results were compared with clinical observations...
  13. doi request reprint Tissue engineering of periosteal cell membranes in vitro
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    Clin Oral Implants Res 20:761-6. 2009
    ..The aim of this study was to test the ability of four collagen membranes to support and promote the proliferation of human periosteal cells...
  14. ncbi request reprint The sebaceous nevus as part of the Schimmelpenning-Feuerstein-Mims Syndrome--an obvious phacomatosis first documented in 1927
    P H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Strasse 16, 24105 Kiel, Germany
    J Cutan Pathol 30:470-2. 2003
    ..We suggest that diagnosis of the SFM syndrome is simple, considering the special linear arrangement of sebaceous nevi in cases of SFM syndrome...
  15. ncbi request reprint Linear intraoral lesions in the sebaceous nevus syndrome
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    J Am Acad Dermatol 52:62-4. 2005
  16. doi request reprint Endocultivation: the influence of delayed vs. simultaneous application of BMP-2 onto individually formed hydroxyapatite matrices for heterotopic bone induction
    S T Becker
    Department of Oral and Maxillofacial Surgery, Christian Albrechts University Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Int J Oral Maxillofac Surg 41:1153-60. 2012
    ..Delayed application of BMP was less effective for heterotopic bone formation than simultaneous application. A central channel allows homogeneous bone induction directly from the centre of the blocks...
  17. doi request reprint Life-threatening bite injury of the lower lip after use of metamizole
    S T Becker
    Department of Oral and Maxillofacial Surgery, University of Kiel, 24105 Kiel, Germany
    Oral Maxillofac Surg 12:39-41. 2008
    ..We present the case of a 37-year-old woman with an ulcer of the mucosa of the lower lip, which had been present for 10 days, and leucopenia...
  18. ncbi request reprint A new method of monitoring osteomyelitis
    I N G Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, D 24105 Kiel, Germany
    Int J Oral Maxillofac Surg 36:527-32. 2007
    ..An inexpensive tool (US$5 per analysis) for the monitoring of osteomyelitis is described...
  19. doi request reprint Gender and nasal shape: measures for rhinoplasty
    Ingo N Springer
    Department of Oral, Maxillofacial, and Facial Plastic Surgery, University of Kiel, Germany
    Plast Reconstr Surg 121:629-37. 2008
    ..Gender-specific nasal shapes are recommended for rhinoplasty. This study was conducted to clarify whether there truly are gender-related differences and to determine optimal nasal shapes in a Caucasian population...
  20. doi request reprint Endocultivation: does delayed application of BMP improve intramuscular heterotopic bone formation?
    Patrick H Warnke
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Strasse 16, 24105 Kiel, Germany
    J Craniomaxillofac Surg 38:54-9. 2010
    ..The aim of this study was to compare the application of BMP injected simultaneously during matrix implantation with delayed application four weeks after matrix implantation for endocultivation in a rat model...
  21. ncbi request reprint Acceleration of callus maturation using rhOP-1 in mandibular distraction osteogenesis in a rat model
    H Terheyden
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105 Kiel, Germany
    Int J Oral Maxillofac Surg 32:528-33. 2003
    ..A continuous bony bridging was seen in all rhOP-1 sites and in none of the control sites. The data indicate that rhOP-1 may be an option to accelerate callus maturation in mandibular distraction osteogenesis...
  22. ncbi request reprint [Critical odontogenic infection involving the mediastinum. Case report]
    M S Bartsch
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Christian Albrechts Universitat zu Kiel
    Mund Kiefer Gesichtschir 9:257-62. 2005
    ..Over the past decade the number of critical infections has increased in other medical specialties. This is usually explained by the development of multiresistant pathogens in the context of nosocomial infections...
  23. doi request reprint Platelet-rich fibrin membranes as scaffolds for periosteal tissue engineering
    Volker Gassling
    Department of Oral and Maxillofacial Surgery, University of Schleswig Holstein, Kiel, Germany
    Clin Oral Implants Res 21:543-9. 2010
    ..The aim is a comparison of PRF with the commonly used collagen membrane Bio-Gide as scaffolds for periosteal tissue engineering...
  24. doi request reprint HDR brachytherapy irradiation of the jaw - as a new experimental model of radiogenic bone damage
    Peter Niehoff
    Department of Radiotherapy Radiooncology, University of Kiel, Germany
    J Craniomaxillofac Surg 36:203-9. 2008
    ..The goal of this investigation was to establish such a standardised experimental model...
  25. doi request reprint Nasal shape and gender of the observer: implications for rhinoplasty
    Ingo N Springer
    Department of Oral and Maxillofacial and Facial Plastic Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 37:3-7. 2009
    ..In a previous study we focused on gender specific nasal shapes. The aim of this study was to evaluate if preferences in nasal shape are also dependent on the gender of the observer...
  26. doi request reprint Endocultivation: 3D printed customized porous scaffolds for heterotopic bone induction
    Stephan T Becker
    Department of Oral and Maxillofacial Surgery, Christian Albrechts University Kiel, Germany
    Oral Oncol 45:e181-8. 2009
    ..Further studies should explore if the stability of the individually designed blocks is sufficient to cultivate larger replacements without an external matrix for support...
  27. doi request reprint Massive swelling of the cervical region: an uncommon manifestation of B cell chronic lymphocytic leukemia
    Stephan T Becker
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, 24105, Kiel, Germany
    Oral Maxillofac Surg 12:205-8. 2008
    ..We suggest that plastic surgeons may refer to magnetic resonance tomography imaging and blood cell counts prior to liposuction of a massive swelling of the neck...
  28. doi request reprint Porous polymer/hydroxyapatite scaffolds: characterization and biocompatibility investigations
    Timothy Douglas
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Strasse 16, 24105, Kiel, Germany
    J Mater Sci Mater Med 20:1909-15. 2009
    ..It was shown that PLGA-HAP composites support osteoblast growth and vitality, paving the way for applications as bone tissue engineering scaffolds...
  29. doi request reprint Novel ceramic bone replacement material CeraBall seeded with human mesenchymal stem cells
    Timothy Douglas
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    Clin Oral Implants Res 21:262-7. 2010
    ..The goal of this study was to characterise 4 and 6 mm CeraBall scaffolds in vitro with a view to their future use as bone replacement materials...
  30. doi request reprint Morbidity after iliac crest bone graft harvesting over an anterior versus posterior approach
    Stephan T Becker
    Department of Oral and Maxillofacial Surgery, Christian Albrechts University, Kiel, Germany
    J Oral Maxillofac Surg 69:48-53. 2011
    ..This study assesses iliac morbidity after bone graft harvesting from the anterior and posterior ilium...
  31. doi request reprint Biocompatibility of individually designed scaffolds with human periosteum for use in tissue engineering
    Stephan T Becker
    Department of Oral and Maxillofacial Surgery, Christian Albrechts University of Kiel, Kiel, Germany
    J Mater Sci Mater Med 21:1255-62. 2010
    ..Conclusion: It can be concluded from our data that the tested materials are biocompatible for periosteal cells and thus can be used as scaffolds to augment bone using tissue engineering methods...
  32. doi request reprint Unilateral atrophy of the cheek: autologous fat injection as treatment of choice
    Volker L W Gassling
    Department of Oral and Maxillofacial Surgery, University Hospital of Schleswig Holstien, Kiel, Germany
    J Craniofac Surg 20:423-5. 2009
    ..According to the patient's wish, a correction of the left cheek was performed by autologous fat injection, which led to a highly acceptable postoperative result. We compare this treatment with different alternatives...
  33. ncbi request reprint Bone graft versus BMP-7 in a critical size defect--cranioplasty in a growing infant model
    Ingo N G Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, D 24105 Kiel, Germany
    Bone 37:563-9. 2005
    ..However, only the quantity not the quality of bone regenerates was different. Our second hypothesis was confirmed: disruption of further cranial development was not seen after bone transplantation or rhBMP-7 implantation...
  34. ncbi request reprint [Facial aesthetics Part II - effect of symmetric and asymmetric modulations of the orbital region]
    Ingo N Springer
    Universitat Kiel, Klinik fur Mund, Kiefer und Gesichtschirurgie, Arnold Heller Str 16, 24105 Kiel, Germany
    Mund Kiefer Gesichtschir 11:233-7. 2007
    ..Small asymmetrical or symmetrical lateral variations did not influence attractiveness negatively...
  35. ncbi request reprint [Facial aesthetics part I - the significance of the triangle of yarbus]
    Ingo N Springer
    Universitat Kiel, Klinik fur Mund, Kiefer und Gesichtschirurgie, Arnold Heller Str 16, 24105 Kiel, Germany
    Mund Kiefer Gesichtschir 11:145-51. 2007
    ..The significance of facial symmetry increases significantly when approaching the Yarbus triangle or the midline, respectively...
  36. ncbi request reprint Craniectomy and noggin application in an infant model
    Ingo N G Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Kiel, Germany
    J Craniomaxillofac Surg 35:177-84. 2007
    ..Secondly, that centrifugal cranial expansion would remain undisturbed whether noggin was applied or not...
  37. ncbi request reprint RhBMP-7 improves survival and eruption in a growing tooth avulsion trauma model
    Ingo N G Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Hellerstr 16, D 24105 Kiel, Germany
    Bone 37:570-7. 2005
    ..002; n=6/group). In conclusion, rhBMP-7 improved survival rates and eruption of replanted teeth in growing individuals. No adverse effects were seen. Based on the present results, future clinical trials appear to be warranted...
  38. ncbi request reprint Radiation caries--radiogenic destruction of dental collagen
    Ingo N Springer
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Strasse 16, D 24105 Kiel, Schleswig Holstein, Germany
    Oral Oncol 41:723-8. 2005
    ..In contrast, direct and instant radiogenic damage of (extracellular matrix) pulpal tissue collagen could be demonstrated...
  39. ncbi request reprint Learning by doing virtually
    N von Sternberg
    University of Hamburg, Department of Oral and Maxillofacial Surgery, Hamburg, Germany
    Int J Oral Maxillofac Surg 36:386-90. 2007
    ..Training with a virtual apicectomy simulator appears to be effective, and the skills acquired are transferable to physical reality...
  40. ncbi request reprint Two techniques for the preparation of cell-scaffold constructs suitable for sinus augmentation: steps into clinical application
    Ingo N Springer
    Department of Oral and Maxillofacial Surgery, University of Schleswig Holstein, Campus Kiel, Kiel, Germany
    Tissue Eng 12:2649-56. 2006
    ..025). No adverse effects were seen. All methods described were capable of creating new bone tissue with sufficient stability for successful implant placement...
  41. ncbi request reprint Detection of mature collagen in human dental enamel
    Yahya Acil
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Strasse 16, D 24105 Kiel, Germany
    Calcif Tissue Int 76:121-6. 2005
    ..We show that this is not the case. However, the concentration of collagen in enamel was considerably lower as compared to that in dentin...
  42. ncbi request reprint Proof of direct radiogenic destruction of collagen in vitro
    Yahya Acil
    Department of Oral and Maxillofacial Surgery, University Hospital Schleswig Holstein, Campus Kiel, Germany
    Strahlenther Onkol 183:374-9. 2007
    ..Fibroses of vessels and soft tissue are side effects of radiotherapy. The authors assumed that there was an immediate direct radiogenic damage of collagen of bone, periosteum and skin...
  43. doi request reprint Psoriasis of the tongue
    Guido C Lier
    Department of Oral and Maxillofacial Surgery, University of Kiel, Germany
    J Craniomaxillofac Surg 37:51-3. 2009
    ..Psoriasis is a common, chronic dermatologic disease. Cases affecting the oral mucous membranes are rarely reported in the international literature, in particular tongue lesions are hardly ever documented...
  44. ncbi request reprint Facial attractiveness: visual impact of symmetry increases significantly towards the midline
    Ingo N Springer
    Department of Oral and Maxillofacial and Facial Plastic Surgery, University of Kiel, Arnold Heller Strasse 16, 24105 Kiel, Germany
    Ann Plast Surg 59:156-62. 2007
    ..Under certain conditions symmetry can be completely unattractive. The visual impact of symmetry on the perception of beauty increases significantly when approaching the midline...
  45. ncbi request reprint Antibacterial essential oils reduce tumor smell and inflammation in cancer patients
    Patrick H Warnke
    J Clin Oncol 23:1588-9. 2005
  46. ncbi request reprint Tumor smell reduction with antibacterial essential oils
    Patrick H Warnke
    Cancer 100:879-80. 2004
  47. ncbi request reprint Wedge excision: treatment of choice in minimal median clefts of the upper lip
    Ingo N G Springer
    Plast Reconstr Surg 114:812-4. 2004
  48. ncbi request reprint Topical phytochemicals used to salvage the gangrenous lower limbs of type 1 diabetic patients
    Eugene Sherry
    Diabetes Res Clin Pract 62:65-6. 2003
  49. doi request reprint Metastatic melanoma of the tongue arising from oral melanosis
    Katharina C Kaehler
    Arch Dermatol 144:558-60. 2008