Research Topics
| C WaltherSummaryAffiliation: University of Leipzig Country: Germany Publications
| Collaborators
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Detail Information
Publications
Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trialClaudia Walther
Department of Cardiology, University of Leipzig, Heart Center, 4289 Leipzig, Germany
Circulation 120:2251-9. 2009....
Increasing physical education in high school students: effects on concentration of circulating endothelial progenitor cellsClaudia Walther
Department of Cardiology, Heart Center, University of Leipzig, Leipzig, Germany
Eur J Cardiovasc Prev Rehabil 15:416-22. 2008..In the context of primary prevention, the impact of regular physical activity on the amount and function of EPC has not yet been investigated in school children...
Regular exercise training compared with percutaneous intervention leads to a reduction of inflammatory markers and cardiovascular events in patients with coronary artery diseaseClaudia Walther
Department of Cardiology, Heart Center, University of Leipzig, Leipzig, Germany
Eur J Cardiovasc Prev Rehabil 15:107-12. 2008..We investigated the impact of 2 years regular ET versus percutaneous intervention (PCI) on chronic inflammation and cardiovascular events...
[Intensified school sports improve fitness]C Walther
Oberärztin der Abt für Kardiologie, Herzzentrum der Universitat Leipzig
MMW Fortschr Med 149:34-5, 37. 2007..Daily periods of inactivity should be limited to fewer than two hours. Measures aimed at improving mobility should be made available in kindergartens, schools and universities...
Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repairYasuharu Matsumoto
Department of Cardiology, Heart Center Leipzig, University of Leipzig, Strumpellstrasse 39, D 04289 Leipzig, Germany
Eur Heart J 30:346-55. 2009..This study investigated whether degenerative AV stenosis (AS) is associated with the presence of valvular endothelial senescence and a reduction in the number and function of endothelial progenitor cells (EPCs)...
Early clinical results after stentless mitral valve implantation and comparison with conventional valve repair or replacementT Walther
University Leipzig, Heartcenter, Department of Cardiac Surgery, Leipzig, Germany
Circulation 100:II78-83. 1999..A new quadricusp stentless mitral bioprosthetic valve (QMV) is evaluated and compared with current standards...
Regression of left ventricular hypertrophy after surgical therapy for aortic stenosis is associated with changes in extracellular matrix gene expressionT Walther
Department of Cardiac Surgery, Heartcenter, University Leipzig, Leipzig, Germany
Circulation 104:I54-8. 2001..The aim of this study was to examine whether there is an association between LVH regression and extracellular matrix (ECM) gene expression...
[Percutaneous revascularization of long-standing chronic occlusion of the superficial femoral artery. A pilot study]H Krankenberg
Herzzentrum der Universitat Leipzig, Klinik für Kardiologie Innere Medizin
Dtsch Med Wochenschr 126:491-5. 2001..It was the aim of our study to evaluate this technique, the initial technical success and the follow-up patency rates after percutaneous revascularization of long chronic occlusion of the the SFA...
Stentless tricuspid valve replacementT Walther
Department of Cardiac Surgery, Heart Center, University of Leipzig, Germany
Ann Thorac Surg 68:1858-9; discussion 1860. 1999..Transvalvular hemodynamics are excellent, and right ventricular function can be preserved by suspending the valve at the papillary muscles...
Quadrileaflet stentless mitral valve replacementT Walther
Department of Cardiac Surgery, Leipzig University, Germany
Thorac Cardiovasc Surg 47:357-60. 1999..The study evaluates clinical results and hemodynamic parameters one year after implantation of a stentless quadrileaflet mitral valve (QMV)...
Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure: A randomized trialR Hambrecht
Klinik für Innere Medizin Kardiologie, Universitat Leipzig, Herzzentrum GmbH, Russenstrasse 19, 04289 Leipzig, Germany
JAMA 283:3095-101. 2000..Exercise training in patients with chronic heart failure improves work capacity by enhancing endothelial function and skeletal muscle aerobic metabolism, but effects on central hemodynamic function are not well established...
Combined stentless mitral valve implantation and radiofrequency ablationT Walther
Department of Heart Surgery, Heartcenter, University of Leipzig, Germany
Ann Thorac Surg 70:1080-2. 2000..The aim of this study was to evaluate the results of combined stentless mitral valve (SMV) replacement and intraoperative radiofrequency ablation for chronic atrial fibrillation (IRAAF) to restore physiologic hemodynamic function...
[Treatment of peripheral arterial thromboembolic occlusions using a new percutaneous mechanical thrombectomy system]H Krankenberg
Universitat Leipzig, Herzzentrum GmbH, Klinik für Kardiologie Innere Medizin
Rofo 173:236-9. 2001..We report our experience with a new percutaneous thrombectomy device for the treatment of thromboembolic occlusions of peripheral arteries...
Images in clinical medicine. Cardiac constriction due to a calcified pericardiumSven Mobius-Winkler
University of Leipzig Heart Center, 04289 Leipzig, Germany
N Engl J Med 355:e19. 2006
Reverse remodeling of cardiac collagen protein expression after surgical therapy for experimental aortic stenosisThomas Walther
University of Leipzig, Heart Center, Clinic for Heart Surgery, Leipzig, Germany
J Heart Valve Dis 15:651-6. 2006..Reversal of myocardial collagen gene expression was examined in parallel to left ventricular reverse remodeling after surgical correction of experimental aortic stenosis...
Changes in myocardial perfusion due to physical exercise in patients with stable coronary artery diseaseKai Kendziorra
Department of Nuclear Medicine, University of Leipzig, Stephanstrasse 9a, 04103, Leipzig, Germany
Eur J Nucl Med Mol Imaging 32:813-9. 2005..The aim of this study was to evaluate changes in myocardial stress perfusion after 1 year of exercise training in comparison with the effects of PTCA in patients with CAD...
Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: a randomized trialRainer Hambrecht
Universitat Leipzig, Herzzentrum GmbH, Klinik für Innere Medizin Kardiologie, Leipzig, Germany
Circulation 109:1371-8. 2004....
Early results with stentless mitral valve replacementThomas Walther
Universitat Leipzig, Herzzentrum, Klinik fur Herzchirurgie, Leipzig, Germany
J Heart Valve Dis 13:766-770; discussion 770-1. 2004..Implantation of a chordally supported stentless mitral valve (SMV) may be the strategy of choice for patients with severe degenerative mitral valve disease. Herein, the early clinical results of this surgical technique were analyzed...
Facilitated endoscopic beating heart coronary artery bypass grafting using a magnetic coupling deviceVolkmar Falk
Department of Cardiac Surgery, Heartcenter, University of Leipzig, Germany
J Thorac Cardiovasc Surg 126:1575-9. 2003..The potential benefits of the endoscopic Magnetic Vascular Positioner device (Ventrica, Inc, Fremont, Calif) to facilitate construction of a coronary anastomosis in a closed chest environment were evaluated...
Exercise training in patients with severe chronic heart failure: impact on left ventricular performance and cardiac size. A retrospective analysis of the Leipzig Heart Failure Training TrialSandra Erbs
, Herzzentrum GmbH, , Leipzig, Germany
Eur J Cardiovasc Prev Rehabil 10:336-44. 2003..CONCLUSIONS: In patients with advanced CHF (NYHA class III), long-term exercise training is associated with an enhanced physical work capacity, an improvement in stroke volume and a reduction in cardiomegaly...
Midterm results after stentless mitral valve replacementThomas Walther
Klinik fur Herzchirurgie, Universitat Leipzig, Herzzentrum, Leipzig, Germany
Circulation 108:II85-9. 2003..To analyze the midterm clinical results after stentless mitral valve (SMV) replacement...
Left ventricular reverse remodeling after surgical therapy for aortic stenosis: correlation to Renin-Angiotensin system gene expressionThomas Walther
Universitat Leipzig, Herzzentrum, Klinik fur Herzchirurgie, Leipzig, Germany
Circulation 106:I23-6. 2002..Surgical therapy for aortic stenosis leads to reverse remodeling, with normalization of left ventricular hypertrophy (LVH). The aim of this study was to examine Renin-Angiotensin system (RAS) gene expression in this setting...
Hemodynamic evaluation of stentless mitral valve replacementThomas Walther
Klinik fur Herzchirurgie, Herzzentrum, Universitat Leipzig, Germany
Artif Organs 26:847-50. 2002..TEE and TTE are extremely useful to assist SMV implantation as well as for regular follow-up evaluation. The hemodynamic function after SMV implantation with preservation of the annulo-ventricular continuity is promising...
Clinical experience with stentless mitral valve replacementFriedrich W Mohr
Heart Center, University of Leipzig, Leipzig, Germany
Ann Thorac Surg 79:772-5. 2005..CONCLUSIONS: The clinical experience after 5.5 years of SMV implantation is promising. Preservation of annuloventricular continuity is advantageous. However, long-term durability remains to be proved...
The effect of exercise training on endothelial function in cardiovascular disease in humansClaudia Walther
University of Leipzig, Heart Center, Department of Internal Medicine/Cardiology, Leipzig, Germany
Exerc Sport Sci Rev 32:129-34. 2004..Regular exercise training is a nonpharmacological option to improve endothelial dysfunction in patients with cardiovascular disease by increasing NO bioavailability...
Anti-inflammatory effects of physical exercise. A new mechanism to explain the benefits of cardiac rehabilitation?Stephan Gielen
J Cardiopulm Rehabil 25:339-42. 2005
