Research Topics
| Christian WalterSummaryAffiliation: University of Mainz Country: Germany Publications
| Collaborators |
Detail Information
Publications
Prevalence of bisphosphonate associated osteonecrosis of the jaw within the field of osteonecrosisChristian Walter
Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131, Mainz, Germany
Support Care Cancer 15:197-202. 2007..Prevalence of bisphosphonate-associated osteonecrosis of the jaws within the catchment area of a university hospital maxillofacial unit and to review the outcome of treatment...
Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitroC Walter
Department of Oral and Maxillofacial Surgery, Plastic Surgery, Johannes Gutenberg University Mainz, Mainz, Germany
Oral Dis 17:194-9. 2011..The aim of this in vitro study was to investigate the effect of different potent bisphosphonates on osteoblasts, fibroblasts and human umbilicord vein endothelial cells (HUVEC)...
Prevalence of bisphosphonate associated osteonecrosis of the jaws in multiple myeloma patientsChristian Walter
Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131 Mainz, Deutschland
Head Face Med 6:11. 2010..Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is an adverse effect of bisphosphonate treatment with varying reported incidence rates...
Incidence of bisphosphonate-associated osteonecrosis of the jaws in breast cancer patientsChristian Walter
Klinik fur Mund, Kiefer und Gesichtschirurgie Johannes Gutenberg Universität Mainz, Mainz, Germany
Cancer 115:1631-7. 2009..Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is a relatively new disease. The aim of this study was to evaluate the prevalence of BP-ONJ in breast cancer patients with osseous metastasis and bisphosphonate therapy...
Prevalence and risk factors of bisphosphonate-associated osteonecrosis of the jaw in prostate cancer patients with advanced disease treated with zoledronateChristian Walter
Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Mainz, Germany
Eur Urol 54:1066-72. 2008..Since 2003, a previously unknown side-effect of bisphosphonates-bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ)-has been described, and frequency has since increased. An exact incidence is still unknown...
Influence of bisphosphonates on the osteoblast RANKL and OPG gene expression in vitroFelix Peter Koch
Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Mainz, Germany
Clin Oral Investig 16:79-86. 2012..Interestingly, clodronate might have little influence on osteoblast/osteoclast interaction with respect to OPG and RANKL gene expression...
The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro studyAndreas M Pabst
Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
Clin Oral Investig 16:87-93. 2012..Furthermore, this in vitro study confirms the theory that perioperative interruption of bisphosphonate application during dental surgical procedures might be feasible to promote better tissue regeneration and wound healing...
Zoledronate, ibandronate and clodronate enhance osteoblast differentiation in a dose dependent manner--a quantitative in vitro gene expression analysis of Dlx5, Runx2, OCN, MSX1 and MSX2Felix Peter Koch
Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University Mainz, Augustusplatz 2, Mainz, Germany
J Craniomaxillofac Surg 39:562-9. 2011..The nitrogen-containing bisphosphonates appear to enhance bone density by stimulation of osteoblast differentiation. Non-nitrogen-containing bisphosphonates seem to have less influence on osteoblast differentiation...
Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitroThomas Ziebart
Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131 Mainz, Germany
Clin Oral Investig 15:105-11. 2011..The increased impact by highly potent bisphosphonates on HUVEC and EPC may explain the high prevalence of BP-ONJ in patients undergoing this treatment...
Actinomycosis of the jaws--histopathological study of 45 patients shows significant involvement in bisphosphonate-associated osteonecrosis and infected osteoradionecrosisTorsten Hansen
Institute of Pathology, University of Mainz, Langenbeckstr 1, 55101, Mainz, Germany
Virchows Arch 451:1009-17. 2007..Patients with Actinomycosis of the jaws during or after these forms of anti-cancer therapy are suggested to represent a distinct patient cohort with a relevant impairment of their general condition...
Interactions between endothelial progenitor cells (EPC) and titanium implant surfacesThomas Ziebart
Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
Clin Oral Investig 17:301-9. 2013..The aim of our in vitro study was to investigate the reactions of EPCs in contact with different commercially available implant surfaces...
Osteonecrosis of the jaw related to sunitinibFelix P Koch
Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University, Mund, Kiefer und Gesichtschirurgie, Mainz, Germany
Oral Maxillofac Surg 15:63-6. 2011..CONCLUSIONS: Bisphosphonates had never been applied. With increasing application of multi-kinase inhibitors, complications due to osteonecrosis could occur more frequently...
Increased numbers of osteoclasts expressing cysteine proteinase cathepsin K in patients with infected osteoradionecrosis and bisphosphonate-associated osteonecrosis--a paradoxical observation?Torsten Hansen
Institute of Pathology, Johannes Gutenberg University of Mainz, Langenbeckstr 1, 55101, Mainz, Germany
Virchows Arch 449:448-54. 2006....
Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiationJulia Karbach
Department for Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany
Clin Oral Investig 16:1305-12. 2012..Reduced susceptibility of C. albicans might introduce complications to therapy. Findings of more non-albicans strains show a change in colonization which should be examined in further studies...
