Christian Walter

Summary

Affiliation: University of Mainz
Country: Germany

Publications

  1. doi request reprint Analysis of reasons for osteonecrosis of the jaws
    Christian Walter
    Oral and Maxillofacial Surgery Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:2221-6. 2014
  2. doi request reprint Radiologic bone loss in patients with bisphosphonate-associated osteonecrosis of the jaws: a case-control study
    Christian Walter
    Oral and Maxillofacial Surgery Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:385-90. 2014
  3. doi request reprint The anatomy of non-carious cervical lesions
    C Walter
    Oral and Maxillofacial Surgery, University Medical Center Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:139-46. 2014
  4. doi request reprint Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro
    C Walter
    Department of Oral and Maxillofacial Surgery, Plastic Surgery, Johannes Gutenberg University Mainz, Mainz, Germany
    Oral Dis 17:194-9. 2011
  5. pmc Prevalence of bisphosphonate associated osteonecrosis of the jaws in multiple myeloma patients
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131 Mainz, Deutschland
    Head Face Med 6:11. 2010
  6. ncbi request reprint Prevalence of bisphosphonate associated osteonecrosis of the jaw within the field of osteonecrosis
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Support Care Cancer 15:197-202. 2007
  7. doi request reprint Incidence of bisphosphonate-associated osteonecrosis of the jaws in breast cancer patients
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie Johannes Gutenberg Universit├Ąt Mainz, Mainz, Germany
    Cancer 115:1631-7. 2009
  8. doi request reprint Prevalence and risk factors of bisphosphonate-associated osteonecrosis of the jaw in prostate cancer patients with advanced disease treated with zoledronate
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Mainz, Germany
    Eur Urol 54:1066-72. 2008
  9. doi request reprint Influence of bisphosphonates on the osteoblast RANKL and OPG gene expression in vitro
    Felix Peter Koch
    Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Mainz, Germany
    Clin Oral Investig 16:79-86. 2012
  10. doi request reprint The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study
    Andreas M Pabst
    Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 16:87-93. 2012

Detail Information

Publications27

  1. doi request reprint Analysis of reasons for osteonecrosis of the jaws
    Christian Walter
    Oral and Maxillofacial Surgery Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:2221-6. 2014
    ..The aim of this retrospective study was to analyze the frequency and overall proportion of BP-ONJ within the field of osteonecrosis. The data was compared to a similar study performed in 2005...
  2. doi request reprint Radiologic bone loss in patients with bisphosphonate-associated osteonecrosis of the jaws: a case-control study
    Christian Walter
    Oral and Maxillofacial Surgery Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:385-90. 2014
    ..The aim of this study was to evaluate the periodontal status of BP-ONJ patients using panoramic radiographs compared to a control...
  3. doi request reprint The anatomy of non-carious cervical lesions
    C Walter
    Oral and Maxillofacial Surgery, University Medical Center Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:139-46. 2014
    ..Two very distinct variations are known: wedge-shaped and saucer-shaped lesions. Reasons for occurrence of two forms might include different contributing factors...
  4. doi request reprint Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro
    C Walter
    Department of Oral and Maxillofacial Surgery, Plastic Surgery, Johannes Gutenberg University Mainz, Mainz, Germany
    Oral Dis 17:194-9. 2011
    ..The aim of this in vitro study was to investigate the effect of different potent bisphosphonates on osteoblasts, fibroblasts and human umbilicord vein endothelial cells (HUVEC)...
  5. pmc Prevalence of bisphosphonate associated osteonecrosis of the jaws in multiple myeloma patients
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131 Mainz, Deutschland
    Head Face Med 6:11. 2010
    ..Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is an adverse effect of bisphosphonate treatment with varying reported incidence rates...
  6. ncbi request reprint Prevalence of bisphosphonate associated osteonecrosis of the jaw within the field of osteonecrosis
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Support Care Cancer 15:197-202. 2007
    ..Prevalence of bisphosphonate-associated osteonecrosis of the jaws within the catchment area of a university hospital maxillofacial unit and to review the outcome of treatment...
  7. doi request reprint Incidence of bisphosphonate-associated osteonecrosis of the jaws in breast cancer patients
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie Johannes Gutenberg Universit├Ąt Mainz, Mainz, Germany
    Cancer 115:1631-7. 2009
    ..Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is a relatively new disease. The aim of this study was to evaluate the prevalence of BP-ONJ in breast cancer patients with osseous metastasis and bisphosphonate therapy...
  8. doi request reprint Prevalence and risk factors of bisphosphonate-associated osteonecrosis of the jaw in prostate cancer patients with advanced disease treated with zoledronate
    Christian Walter
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Mainz, Germany
    Eur Urol 54:1066-72. 2008
    ..Since 2003, a previously unknown side-effect of bisphosphonates-bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ)-has been described, and frequency has since increased. An exact incidence is still unknown...
  9. doi request reprint Influence of bisphosphonates on the osteoblast RANKL and OPG gene expression in vitro
    Felix Peter Koch
    Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Mainz, Germany
    Clin Oral Investig 16:79-86. 2012
    ..Interestingly, clodronate might have little influence on osteoblast/osteoclast interaction with respect to OPG and RANKL gene expression...
  10. doi request reprint The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study
    Andreas M Pabst
    Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 16:87-93. 2012
    ..Furthermore, this in vitro study confirms the theory that perioperative interruption of bisphosphonate application during dental surgical procedures might be feasible to promote better tissue regeneration and wound healing...
  11. doi request reprint Zoledronate, ibandronate and clodronate enhance osteoblast differentiation in a dose dependent manner--a quantitative in vitro gene expression analysis of Dlx5, Runx2, OCN, MSX1 and MSX2
    Felix Peter Koch
    Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University Mainz, Augustusplatz 2, Mainz, Germany
    J Craniomaxillofac Surg 39:562-9. 2011
    ..The nitrogen-containing bisphosphonates appear to enhance bone density by stimulation of osteoblast differentiation. Non-nitrogen-containing bisphosphonates seem to have less influence on osteoblast differentiation...
  12. doi request reprint Osteogenic differentiation of periodontal fibroblasts is dependent on the strength of mechanical strain
    Collin Jacobs
    Department of Orthodontics, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany
    Arch Oral Biol 58:896-904. 2013
    ..Aim of this study was to investigate the osteogenic differentiation of human periodontal ligament fibroblasts (HPdLF) depending on the applied strength of mechanical strain compared to osteoblasts (HOB)...
  13. pmc Current state of orthodontic patients under bisphosphonate therapy
    Elena Krieger
    Department of Orthodontics, Medical Centre of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany
    Head Face Med 9:10. 2013
    ..Therefore, the aim of this research was to evaluate and demonstrate the reported effects and the current state of scientific research regarding orthodontic treatment and bisphosphonate medication exclusively in humans...
  14. doi request reprint Interactions between endothelial progenitor cells (EPC) and titanium implant surfaces
    Thomas Ziebart
    Department of Oral and Maxillofacial Surgery, University medical centre of Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 17:301-9. 2013
    ..The aim of our in vitro study was to investigate the reactions of EPCs in contact with different commercially available implant surfaces...
  15. doi request reprint Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro
    Thomas Ziebart
    Klinik fur Mund, Kiefer und Gesichtschirurgie, Johannes Gutenberg Universitat Mainz, Augustusplatz 2, 55131 Mainz, Germany
    Clin Oral Investig 15:105-11. 2011
    ..The increased impact by highly potent bisphosphonates on HUVEC and EPC may explain the high prevalence of BP-ONJ in patients undergoing this treatment...
  16. ncbi request reprint Actinomycosis of the jaws--histopathological study of 45 patients shows significant involvement in bisphosphonate-associated osteonecrosis and infected osteoradionecrosis
    Torsten Hansen
    Institute of Pathology, University of Mainz, Langenbeckstr 1, 55101, Mainz, Germany
    Virchows Arch 451:1009-17. 2007
    ..Patients with Actinomycosis of the jaws during or after these forms of anti-cancer therapy are suggested to represent a distinct patient cohort with a relevant impairment of their general condition...
  17. doi request reprint Mechanical loading influences the effects of bisphosphonates on human periodontal ligament fibroblasts
    Collin Jacobs
    Department of Orthodontics, Medical Center, Johannes Gutenberg of University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 19:699-708. 2015
    ..The object of the study was to investigate the changes produced by tensile strain on human periodontal ligament fibroblasts (HPdLFs) treated with clodronate or zoledronate...
  18. doi request reprint Induction of IL-6 and MMP-8 in human periodontal fibroblasts by static tensile strain
    Collin Jacobs
    Department of Orthodontics, University Medical Center, Johannes Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 18:901-8. 2014
    ..Aim of this study was to investigate the inflammatory response and synthesis of proteinases by human periodontal ligament fibroblast (HPdLF) dependent on different strengths of static tensile strain (STS)...
  19. doi request reprint Analysis of implant-failure predictors in the posterior maxilla: a retrospective study of 1395 implants
    Andreas Max Pabst
    Department of Oral and Maxillofacial Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany Electronic address
    J Craniomaxillofac Surg 43:414-20. 2015
    ..6 mm), the middle- (3.6-4.5 mm) and the wide diameter implants (>4.5 mm) were 92.5%, 87.9% and 89.6%, respectively (p = 0.0425). None of the parameters evaluated were identified as predictor of implant failure in the posterior maxilla...
  20. doi request reprint Influence of osteotomy procedure and surgical experience on early complications after orthognathic surgery in the mandible
    Bilal Al-Nawas
    Department of Oral, Maxillofacial and Plastic Surgery, Head Univ Prof Dr Med Dr Med Dent Wilfried Wagner, University Medical Centre Mainz, Augustusplatz 2, 55131 Mainz, Germany
    J Craniomaxillofac Surg 42:e284-8. 2014
    ..This study evaluated the influence of osteotomy procedure and surgical experience on early complication rates following orthognathic surgery in the mandible...
  21. doi request reprint Osteonecrosis of the jaw related to sunitinib
    Felix P Koch
    Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University, Mund, Kiefer und Gesichtschirurgie, Mainz, Germany
    Oral Maxillofac Surg 15:63-6. 2011
    ..After initial therapy with interferon and vinblastine, a relapse occurred and the therapy was changed to sorafenib, followed by sunitinib. Osteonecrosis of the lower jaw appeared 1 year after initial and exclusive therapy with sunitinib...
  22. ncbi request reprint Increased numbers of osteoclasts expressing cysteine proteinase cathepsin K in patients with infected osteoradionecrosis and bisphosphonate-associated osteonecrosis--a paradoxical observation?
    Torsten Hansen
    Institute of Pathology, Johannes Gutenberg University of Mainz, Langenbeckstr 1, 55101, Mainz, Germany
    Virchows Arch 449:448-54. 2006
    ....
  23. pmc Malignant lymphomas in the head and neck region--a retrospective, single-center study over 41 years
    Christian Walter
    1 Oral and Maxillofacial Surgery Plastic Surgery of the University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany
    Int J Med Sci 12:141-5. 2015
    ..The aim of this study was to retrospectively investigate the site of occurrence of lymphomas in the head and neck area and to analyze the typical symptoms of patients who presented at an oral and maxillofacial surgical department...
  24. doi request reprint In vitro effects of bisphosphonates on chemotaxis, phagocytosis, and oxidative burst of neutrophil granulocytes
    Nadine Hagelauer
    Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg University, Augustusplatz 2, 55131, Mainz, Germany
    Clin Oral Investig 19:139-48. 2015
    ..Neutrophil granulocytes are essential for sufficient wound healing; therefore, the influence of different bisphosphonates on neutrophil granulocytes was the focus of this study...
  25. doi request reprint Concomitant dental injuries in maxillofacial fractures - a retrospective analysis of 1219 patients
    Roman K Rahimi-Nedjat
    Department of Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    Dent Traumatol 30:435-41. 2014
    ..In a retrospective study, the frequency of dental lesions in inpatients with traumatic facial injuries was analyzed...
  26. doi request reprint [Orthodontic treatment of patients medicated with bisphosphonates-a clinical case report]
    Elena Krieger
    Department of Orthodontics, Medical Center of Johannes Gutenberg University Mainz, Mainz, Germany
    J Orofac Orthop 74:28-39. 2013
    ..Bisphosphonates (BP) are an established medication, e.g., for the prevention/therapy of osteoporosis. The effects of the changed bone metabolism for orthodontic treatments are unknown...
  27. doi request reprint Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation
    Julia Karbach
    Department for Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Augustusplatz 2, 55131 Mainz, Germany
    Clin Oral Investig 16:1305-12. 2012
    ..Reduced susceptibility of C. albicans might introduce complications to therapy. Findings of more non-albicans strains show a change in colonization which should be examined in further studies...