Barbara Waidner

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi request reprint Pathogenesis of Helicobacter pylori infection
    Paul Hofman
    INSERM 0215 and Laboratory of Clinical and Experimental Pathology, Faculty of Medicine and Pasteur Hospital, University of Nice, 06002 Nice, France
    Helicobacter 9:15-22. 2004
  2. pmc Helicobacter pylori possesses four coiled-coil-rich proteins that form extended filamentous structures and control cell shape and motility
    Mara Specht
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann Herder Straße 11, D 79104 Freiburg, Germany
    J Bacteriol 193:4523-30. 2011
  3. pmc A novel system of cytoskeletal elements in the human pathogen Helicobacter pylori
    Barbara Waidner
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Freiburg, Germany
    PLoS Pathog 5:e1000669. 2009
  4. pmc The Helicobacter pylori CrdRS two-component regulation system (HP1364/HP1365) is required for copper-mediated induction of the copper resistance determinant CrdA
    Barbara Waidner
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann Herder Strasse 11, D 79104 Freiburg, Germany
    J Bacteriol 187:4683-8. 2005
  5. pmc Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori
    Barbara Waidner
    Department of Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, D 79104 Freiburg, Germany
    J Bacteriol 184:6700-8. 2002
  6. pmc Magnesium uptake by CorA is essential for viability of the gastric pathogen Helicobacter pylori
    Jens Pfeiffer
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital of Freiburg, D 79104 Freiburg, Germany
    Infect Immun 70:3930-4. 2002
  7. pmc Localization of FtsZ in Helicobacter pylori and consequences for cell division
    Mara Specht
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Freiburg, Germany
    J Bacteriol 195:1411-20. 2013
  8. pmc Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization
    Barbara Waidner
    Institute of Medical Microbiology and Hygiene, Department of Medical Microbiology and Hygiene, University Hospital of Freiburg, Germany
    Infect Immun 70:3923-9. 2002
  9. pmc The putative assembly factor CcoH is stably associated with the cbb3-type cytochrome oxidase
    Grzegorz Pawlik
    Institut fur Biochemie und Molekularbiologie, Albert Ludwigs Universitat Freiburg, D 79104 Freiburg, Germany
    J Bacteriol 192:6378-89. 2010
  10. ncbi request reprint An interferon-gamma-binding protein of novel structure encoded by the fowlpox virus
    Florian Puehler
    Department of Virology, University of Freiburg, D 79104 Freiburg, Germany
    J Biol Chem 278:6905-11. 2003

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Pathogenesis of Helicobacter pylori infection
    Paul Hofman
    INSERM 0215 and Laboratory of Clinical and Experimental Pathology, Faculty of Medicine and Pasteur Hospital, University of Nice, 06002 Nice, France
    Helicobacter 9:15-22. 2004
    ..pylori. There is still a lot to be learned, but the promising discoveries summarized here, demonstrate that the investigation of the bacterial survival strategies will give novel insights into pathogenesis and disease development...
  2. pmc Helicobacter pylori possesses four coiled-coil-rich proteins that form extended filamentous structures and control cell shape and motility
    Mara Specht
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann Herder Straße 11, D 79104 Freiburg, Germany
    J Bacteriol 193:4523-30. 2011
    ..Despite the presence of morphologically unaltered flagella, all ccrp mutants displayed significantly reduced motility...
  3. pmc A novel system of cytoskeletal elements in the human pathogen Helicobacter pylori
    Barbara Waidner
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Freiburg, Germany
    PLoS Pathog 5:e1000669. 2009
    ..pylori. Our findings reveal that Ccrp proteins, but not MreB, affect cell morphology, while both cytoskeletal components affect the development of pathogenicity factors and/or cell cycle progression...
  4. pmc The Helicobacter pylori CrdRS two-component regulation system (HP1364/HP1365) is required for copper-mediated induction of the copper resistance determinant CrdA
    Barbara Waidner
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann Herder Strasse 11, D 79104 Freiburg, Germany
    J Bacteriol 187:4683-8. 2005
    ..A direct role of CrdR in transcriptional regulation of crdA was confirmed by in vitro binding of CrdR to the crdA upstream region. A 21-nucleotide sequence located near the crdA promoter was shown to be required for CrdR binding...
  5. pmc Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori
    Barbara Waidner
    Department of Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, D 79104 Freiburg, Germany
    J Bacteriol 184:6700-8. 2002
    ..In summary, results from RNA profiling identified the novel H. pylori-specific copper resistance determinants CrdA (HP1326) and CrdB (HP1327), which are required for adaptation to copper-rich environmental conditions...
  6. pmc Magnesium uptake by CorA is essential for viability of the gastric pathogen Helicobacter pylori
    Jens Pfeiffer
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital of Freiburg, D 79104 Freiburg, Germany
    Infect Immun 70:3930-4. 2002
    ..pylori. The drastic Mg(2+) requirement (20 mM) of H. pylori corA mutants indicates that CorA plays a key role in the adaptation to the low-Mg(2+) conditions predominant in the gastric environment...
  7. pmc Localization of FtsZ in Helicobacter pylori and consequences for cell division
    Mara Specht
    Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Freiburg, Germany
    J Bacteriol 195:1411-20. 2013
    ..pylori and E. coli FtsZ filaments in the heterologous system of Drosophila melanogaster S2 Schneider cells revealed that both have different filamentation properties in vivo, suggesting a unique intrinsic characteristic of each protein...
  8. pmc Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization
    Barbara Waidner
    Institute of Medical Microbiology and Hygiene, Department of Medical Microbiology and Hygiene, University Hospital of Freiburg, Germany
    Infect Immun 70:3923-9. 2002
    ..In summary, the pfr phenotypes observed give new insights into prokaryotic ferritin functions and indicate that iron storage and homeostasis are of extraordinary importance for H. pylori to survive in its hostile natural environment...
  9. pmc The putative assembly factor CcoH is stably associated with the cbb3-type cytochrome oxidase
    Grzegorz Pawlik
    Institut fur Biochemie und Molekularbiologie, Albert Ludwigs Universitat Freiburg, D 79104 Freiburg, Germany
    J Bacteriol 192:6378-89. 2010
    ..Thus, CcoH behaves more like a bona fide subunit of the cbb(3)-Cox than an assembly factor per se...
  10. ncbi request reprint An interferon-gamma-binding protein of novel structure encoded by the fowlpox virus
    Florian Puehler
    Department of Virology, University of Freiburg, D 79104 Freiburg, Germany
    J Biol Chem 278:6905-11. 2003
    ....
  11. pmc Iron-responsive regulation of the Helicobacter pylori iron-cofactored superoxide dismutase SodB is mediated by Fur
    Florian D Ernst
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Dijkzigt L 4, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    J Bacteriol 187:3687-92. 2005
    ..In conclusion, H. pylori Fur is a versatile regulator involved in many pathways essential for gastric colonization, including superoxide stress defense...
  12. ncbi request reprint Transcriptional profiling of Helicobacter pylori Fur- and iron-regulated gene expression
    Florian D Ernst
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Dijkzigt L 455, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Microbiology 151:533-46. 2005
    ..pylori Fur is a versatile regulator involved in many pathways essential for gastric colonization. These findings further delineate the central role of Fur in regulating the unique capacity of H. pylori to colonize the human stomach...
  13. pmc The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistance
    Jetta J E Bijlsma
    Department of Medical Microbiology, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    Infect Immun 70:606-11. 2002
    ..From this we conclude that Fur is involved in the growth at acidic pH of H. pylori; as such, it is the first regulatory protein implicated in the acid resistance of this important human pathogen...