J Volkmann

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. doi request reprint Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: a randomised, multicentre study
    Karsten Witt
    Christian Albrechts University, Kiel, Germany
    Lancet Neurol 7:605-14. 2008
  2. ncbi request reprint Long-term results of bilateral pallidal stimulation in Parkinson's disease
    Jens Volkmann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Cologne, Germany
    Ann Neurol 55:871-5. 2004
  3. doi request reprint Neuropsychiatric effects of subthalamic neurostimulation in Parkinson disease
    Jens Volkmann
    Department of Neurology, Universitatsklinikum Schleswig Holstein, Campus Kiel, Arnold Heller Strasse 3, Haus 41, 24105 Kiel, Germany
    Nat Rev Neurol 6:487-98. 2010
  4. ncbi request reprint Introduction to the programming of deep brain stimulators
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 17:S181-7. 2002
  5. ncbi request reprint Deep brain stimulation for dystonia: patient selection and evaluation
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 17:S112-5. 2002
  6. doi request reprint Deep brain stimulation for Parkinson's disease
    J Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Parkinsonism Relat Disord 13:S462-5. 2007
  7. ncbi request reprint Update on surgery for Parkinson's disease
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Curr Opin Neurol 20:465-9. 2007
  8. ncbi request reprint Basic algorithms for the programming of deep brain stimulation in Parkinson's disease
    Jens Volkmann
    Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
    Mov Disord 21:S284-9. 2006
  9. doi request reprint Long-term effects of pallidal or subthalamic deep brain stimulation on quality of life in Parkinson's disease
    Jens Volkmann
    Neurologische Klinik der Christian Albrechts Universität, Kiel, Germany
    Mov Disord 24:1154-61. 2009
  10. doi request reprint Failure of deep brain stimulation of the posterior inferior hypothalamus in chronic cluster headache - report of two cases and review of the literature
    M O Pinsker
    Department of Neurosurgery, UK SH, Kiel, Kiel, Germany
    Zentralbl Neurochir 69:76-9. 2008

Collaborators

Detail Information

Publications76

  1. doi request reprint Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: a randomised, multicentre study
    Karsten Witt
    Christian Albrechts University, Kiel, Germany
    Lancet Neurol 7:605-14. 2008
    ..To assess the neuropsychiatric consequences of DBS in patients with PD we did an ancillary protocol as part of a randomised study that compared DBS with the best medical treatment...
  2. ncbi request reprint Long-term results of bilateral pallidal stimulation in Parkinson's disease
    Jens Volkmann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Cologne, Germany
    Ann Neurol 55:871-5. 2004
    ..Replacement of pallidal electrodes into the subthalamic nucleus in four patients could restore the initial benefit of deep brain stimulation and allowed a significant reduction of dopaminergic drug therapy...
  3. doi request reprint Neuropsychiatric effects of subthalamic neurostimulation in Parkinson disease
    Jens Volkmann
    Department of Neurology, Universitatsklinikum Schleswig Holstein, Campus Kiel, Arnold Heller Strasse 3, Haus 41, 24105 Kiel, Germany
    Nat Rev Neurol 6:487-98. 2010
    ..Here, we summarize the neuropsychiatric changes observed after STN HFS and try to disentangle their various etiologies...
  4. ncbi request reprint Introduction to the programming of deep brain stimulators
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 17:S181-7. 2002
    ..They also describe noninvasive technical trouble shooting by using programming features of the commercially available neurostimulation devices...
  5. ncbi request reprint Deep brain stimulation for dystonia: patient selection and evaluation
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 17:S112-5. 2002
    ..This article discusses the different factors influencing patient selection for surgical treatment and describes standardized methods and the caveats for clinical documentation of treatment results in dystonia...
  6. doi request reprint Deep brain stimulation for Parkinson's disease
    J Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Parkinsonism Relat Disord 13:S462-5. 2007
    ..Current evidence suggests that for patients fulfilling these selection criteria deep brain stimulation of the subthalamic nucleus is superior to standard oral drug therapy in maintaining a good level of health-related quality of life...
  7. ncbi request reprint Update on surgery for Parkinson's disease
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Curr Opin Neurol 20:465-9. 2007
    ....
  8. ncbi request reprint Basic algorithms for the programming of deep brain stimulation in Parkinson's disease
    Jens Volkmann
    Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
    Mov Disord 21:S284-9. 2006
    ..The basic programming algorithms for thalamic, subthalamic, and pallidal stimulation in PD are explained and summarized in flowcharts...
  9. doi request reprint Long-term effects of pallidal or subthalamic deep brain stimulation on quality of life in Parkinson's disease
    Jens Volkmann
    Neurologische Klinik der Christian Albrechts Universität, Kiel, Germany
    Mov Disord 24:1154-61. 2009
    ..Despite sustained motor improvements many of these initial benefits were lost after 3 years. This may reflect either progression of the disease or adaptive changes in the subjective perception of health-related wellbeing over time...
  10. doi request reprint Failure of deep brain stimulation of the posterior inferior hypothalamus in chronic cluster headache - report of two cases and review of the literature
    M O Pinsker
    Department of Neurosurgery, UK SH, Kiel, Kiel, Germany
    Zentralbl Neurochir 69:76-9. 2008
    ..Recently, deep brain stimulation of the posterior hypothalamus has been shown to be effective in the treatment of drug-resistant chronic cluster headache...
  11. doi request reprint Accuracy and distortion of deep brain stimulation electrodes on postoperative MRI and CT
    M O Pinsker
    Department of Neurosurgery, UK SH, Kiel, Germany
    Zentralbl Neurochir 69:144-7. 2008
    ..The goal of this study was to determine the relation and size of these artefacts to the electrodes by comparing the position of the electrodes in postoperative MR and CT imaging...
  12. doi request reprint Deep brain stimulation of the internal globus pallidus in dystonia: target localisation under general anaesthesia
    M O Pinsker
    Department of Neurosurgery, University Hospital of Schleswig Holstein, Campus Kiel, Kiel, Germany
    Acta Neurochir (Wien) 151:751-8. 2009
    ....
  13. doi request reprint Neuronal activity of the human subthalamic nucleus in the parkinsonian and nonparkinsonian state
    F Steigerwald
    Department of Neurology, Christian Albrechts Universitat Kiel, Schittenhelmstr 10, D 24105 Kiel, Germany
    J Neurophysiol 100:2515-24. 2008
    ..In addition, they emphasize abnormalities in the patterning and dynamics of neuronal discharges in the parkinsonian STN, which support current concepts of abnormal motor loop oscillations in Parkinson's disease...
  14. doi request reprint Subthalamic nucleus stimulation modulates audiospinal reactions in Parkinson disease
    M Potter
    Department of Neurology, Christian Albrechts University, Schittenhelmstr 10 m D 24105 Kiel, Germany
    Neurology 70:1445-51. 2008
    ..In this study, we assessed whether modulation of basal ganglia activity by high-frequency stimulation of the subthalamic nucleus (STN-HFS) in PD had an impact on the brainstem-controlled startle system...
  15. doi request reprint Kinematic effects of subthalamic stimulation on reach-to-grasp movements in Parkinson's disease
    M Pötter-Nerger
    Dept of Neurology, Christian Albrecht University, Kiel, Germany
    Parkinsonism Relat Disord 19:32-6. 2013
    ..Parkinsonian patients demonstrate particular difficulties when performing sequential motor tasks compared to simple movements indicating an important role of the basal ganglia in switching between different motor programs...
  16. ncbi request reprint Safety and efficacy of pallidal or subthalamic nucleus stimulation in advanced PD
    J Volkmann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Neurology 56:548-51. 2001
    ..These advantages contrasted with a need for more intensive postoperative monitoring and a higher incidence of adverse events related to levodopa withdrawal...
  17. doi request reprint Electrode implantation for deep brain stimulation in dystonia: a fast spin-echo inversion-recovery sequence technique for direct stereotactic targeting of the GPI
    M O Pinsker
    Department of Neurosurgery, UK SH, Kiel, Kiel, Germany
    Zentralbl Neurochir 69:71-5. 2008
    ..We present our technique for direct preoperative visualization of the target using a fast spin-echo inversion-recovery (FSE-IR) sequence...
  18. ncbi request reprint Effect of propofol anesthesia on pallidal neuronal discharges in generalized dystonia
    F Steigerwald
    Department of Neurology, Christian Albrechts University, Schittenhelmstr 10, D 24105 Kiel, Germany
    Neurosci Lett 386:156-9. 2005
    ..Our data support the pathophysiological model of a decreased basal ganglia output in dystonia and argue against a possible pharmacological artifact...
  19. doi request reprint Impact of subthalamic stimulation and medication on proximal and distal bradykinesia in Parkinson's disease
    M Pötter-Nerger
    Department of Neurology, Christian Albrecht University, Kiel, Germany
    Eur Neurol 62:114-9. 2009
    ..To evaluate the usefulness of a new instrument for bedside testing of proximal arm and distal finger tapping performance in patients with Parkinson's disease (PD)...
  20. ncbi request reprint Stimulation of subthalamic fibre tracts reduces dyskinesias in STN-DBS
    J Herzog
    Department of Neurology, Neurozentrum, Christian Albrechts Universitat Kiel, Kiel, Germany
    Mov Disord 22:679-84. 2007
    ..We propose that pallidofugal fiber tracts play a major role in the etiopathology of dyskinesias and their blockade through DBS may explain our observations...
  21. ncbi request reprint Deep brain stimulation of the internal pallidum did not improve chorea in a patient with neuro-acanthocytosis
    G Wihl
    Department of Neurology, Heinrich Heine University Dusseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
    Mov Disord 16:572-5. 2001
    ..Prior to this surgery the patient had experienced a striking but short lived amelioration of symptoms with clozapine therapy...
  22. ncbi request reprint Influence of alcohol on gait in patients with essential tremor
    S Klebe
    Department of Neurology, Christian Albrechts Universitat Kiel, Germany
    Neurology 65:96-101. 2005
    ..To study the effect of ethanol on gait in patients with essential tremor (ET)...
  23. pmc Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: evaluation of active electrode contacts
    W Hamel
    Department of Neurosurgery, Christian Albrechts University, Kiel, Germany
    J Neurol Neurosurg Psychiatry 74:1036-46. 2003
    ..The site of permanent stimulation is the subject of ongoing debate, as stimulation both within and adjacent to the subthalamic nucleus may be effective...
  24. ncbi request reprint Deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a therapy approaching evidence-based standards
    G Deuschl
    Department of Neurology, Christian Albrechts Universitat Kiel, Niemannsweg 147, 24105 Kiel, Germany
    J Neurol 250:I43-6. 2003
    ..Further studies should specifically address the questions of efficacy and side effects as well as the impact on quality of life...
  25. ncbi request reprint Effects of bilateral pallidal or subthalamic stimulation on gait in advanced Parkinson's disease
    N Allert
    Department of Neurology, , Germany
    Mov Disord 16:1076-85. 2001
    ..Hence, the increase in gait velocity in the STN group was almost exclusively due to a significant increase in step length, while in the GPi group statistically non-significant increases in both step length and cadence contributed...
  26. ncbi request reprint Deep brain stimulation for idiopathic or secondary movement disorders
    H M Mehdorn
    Department of Neurosurgery, Christian Albrechts University of Kiel Medical Center, Kiel, Germany
    Acta Neurochir Suppl 93:105-11. 2005
    ..Presenting our clinical series of 179 patients operated upon since 1999, the indications, risks and benefits for the patients are discussed in order to further improve the techniques and their applications...
  27. ncbi request reprint Deep brain stimulation for movement disorders and its neuropsychological implications
    H M Mehdorn
    Department of Neurosurgery, University Clinics of Schleswig Holstein Kiel, Kiel, Germany
    Acta Neurochir Suppl 101:9-12. 2008
    ....
  28. ncbi request reprint Deep brain stimulation for the treatment of Parkinson's disease
    Jens Volkmann
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    J Clin Neurophysiol 21:6-17. 2004
    ....
  29. ncbi request reprint Different cortical organization of visceral and somatic sensation in humans
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Eur J Neurosci 11:305-15. 1999
    ..We propose that this cortical projection pattern forms the neurophysiological basis of the low temporal and spatial resolution of conscious visceral sensation...
  30. doi request reprint Effect of controlled-release levodopa on the microstructure of sleep in Parkinson's disease
    S Wailke
    Department of Neurology, University Hospital Schleswig Holstein, Campus Kiel, Germany
    Eur J Neurol 18:590-6. 2011
    ..Hence, the question arises whether the disrupted sleep pattern in Parkinson's disease (PD) is responsive to dopaminergic treatment...
  31. ncbi request reprint Gait analysis of sporadic and hereditary spastic paraplegia
    S Klebe
    Neurologische Klinik, Christian Albrechts Universitat, Niemannsweg 147, 24105, Kiel, Germany
    J Neurol 251:571-8. 2004
    ..Spastic paraparesis is the major and most disabling clinical symptom and was assessed with gait analysis using a three-dimensional infrared movement analysis system...
  32. ncbi request reprint The effect of subthalamic nucleus stimulation on autogenic inhibition in Parkinson disease
    M Potter
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Neurology 63:1234-9. 2004
    ..The authors investigated the effect of high frequency stimulation of the subthalamic nucleus (STN-HFS) on autogenic inhibition in PD...
  33. ncbi request reprint Treatment of severe tardive dystonia with pallidal deep brain stimulation
    T Trottenberg
    Department of Neurology, Charite Campus Virchow, Humboldt University, Berlin, Germany
    Neurology 64:344-6. 2005
    ..7 SD of the motor part of the Burke-Fahn-Marsden Dystonia Rating Scale) improvement of dystonia and functional disability without adverse events...
  34. doi request reprint Subthalamic nucleus stimulation restores corticospinal facilitation in Parkinson's disease
    Monika Pötter-Nerger
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 23:2210-5. 2008
    ..01). STN-HFS restores the normal facilitatory drive of a transcranially evoked motor cortical response to the spinal motoneuron pool. In addition to subcortical routes, STN-DBS also alters spinal excitability via transcortical pathways...
  35. doi request reprint Influence of subthalamic deep brain stimulation versus levodopa on motor perseverations in Parkinson's disease
    Jan Herzog
    Department of Neurology, Christian Albrechts University, Schittenhelmstr 10, Kiel, Germany
    Mov Disord 24:1206-10. 2009
    ..7 +/- 2.6 (P < 0.001) whereas levodopa had no impact (R(2) reduction 3.7 +/- 1.6, P = 0.081). This demonstrates that STN-DBS, by reducing motor perseveration, influences higher order aspects of motor behavior of patients with PD...
  36. ncbi request reprint The cerebral oscillatory network of parkinsonian resting tremor
    Lars Timmermann
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Brain 126:199-212. 2003
    ..The main frequency of cerebro-cerebral coupling corresponds to double the tremor frequency...
  37. ncbi request reprint Deep-brain stimulation for Parkinson's disease
    G Deuschl
    Department of Neurology, Christian Albrechts Universitat Kiel, Niemannsweg 147, 24105 Kiel, Germany
    J Neurol 249:III/36-9. 2002
    ..However, prospective studies for this procedure are lacking and some clinical problems may be more easily solved with targeting the internal pallidum or the thalamus. Despite major progress in this field, much work remains to be done...
  38. doi request reprint Hypothalamic deep brain stimulation for cluster headache: experience from a new multicase series
    T Bartsch
    Department of Neurology, University Hospital Schleswig Holstein, Kiel, Germany
    Cephalalgia 28:285-95. 2008
    ..Future controlled multicentre trials will need to confirm this open-label experience and should help to better define predictive factors for non-responders...
  39. ncbi request reprint No benefit of 3,4-diaminopyridine in essential tremor: a placebo-controlled crossover study
    D Lorenz
    Department of Neurology, University Hospital Schleswig Holstein, Kiel, Germany
    Neurology 66:1753-5. 2006
    ..They did not find any significant change in tremor severity as measured by clinical ratings or accelerometry...
  40. ncbi request reprint Technical complication in deep brain stimulation
    W Hamel
    Klinik für Neurochirurgie, Universitatsklinikum Kiel, Germany
    Zentralbl Neurochir 63:124-7. 2002
    ..Renewed dislocation of revised extensions may be prevented by securing the position of the connector (e.g. with manipulates)...
  41. ncbi request reprint MRI- and skull x-ray-based approaches to evaluate the position of deep brain stimulation electrode contacts--a technical note
    W Hamel
    Klinik für Neurochirurgie, Universitatsklinikum Kiel
    Zentralbl Neurochir 63:65-9. 2002
    ..18 mm (range 0.42 to 1.93 mm). These data suggest that both approaches may be used to determine the position of single electrode contacts...
  42. ncbi request reprint Kinematic analysis of thalamic versus subthalamic neurostimulation in postural and intention tremor
    Jan Herzog
    Department of Neurology, Christian Albrechts University Kiel, Germany
    Brain 130:1608-25. 2007
    ..The better efficacy of stimulation within the STA compared to thalamus proper favours the concept of a modulation of cerebello-thalamic projections underlying the improvement of these symptoms...
  43. pmc Effects of subthalamic nucleus stimulation and levodopa on the autonomic nervous system in Parkinson's disease
    Janne Ludwig
    Division of Neurological Pain Research and Therapy, University of Kiel, Kiel, Germany
    J Neurol Neurosurg Psychiatry 78:742-5. 2007
    ..Since less pharmacotherapy is needed after STN stimulation, reduced levodopa intake results in relative improvement of autonomic function in deep brain stimulated PD patients...
  44. ncbi request reprint A randomized trial of deep-brain stimulation for Parkinson's disease
    Gunther Deuschl
    Christian Albrechts University, Kiel, Germany
    N Engl J Med 355:896-908. 2006
    ..Neurostimulation of the subthalamic nucleus reduces levodopa-related motor complications in advanced Parkinson's disease. We compared this treatment plus medication with medical management...
  45. doi request reprint Gait ataxia in essential tremor is differentially modulated by thalamic stimulation
    Alfonso Fasano
    Department of Neurology, Christian Albrechts University, 24105 Kiel, Germany
    Brain 133:3635-48. 2010
    ....
  46. ncbi request reprint Patients with Parkinson's disease learn to control complex systems-an indication for intact implicit cognitive skill learning
    Karsten Witt
    Department of Neurology, University Medical Center Schleswig Holstein, Campus Kiel, Germany
    Neuropsychologia 44:2445-51. 2006
    ..These results demonstrate a functional independence of implicit cognitive skill learning and certain aspects of executive functions...
  47. ncbi request reprint Deep brain stimulation: postoperative issues
    Gunther Deuschl
    Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
    Mov Disord 21:S219-37. 2006
    ..The report has been endorsed by the Scientific Issues Committee of the Movement Disorder Society and the American Society of Stereotactic and Functional Neurosurgery...
  48. ncbi request reprint Subthalamic stimulation modulates cortical control of urinary bladder in Parkinson's disease
    Jan Herzog
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Brain 129:3366-75. 2006
    ..The data suggest that STN-DBS ameliorates bladder dysfunction and that this modulation may result from facilitated processing of afferent bladder information...
  49. ncbi request reprint The impact of normal aging and Parkinson's disease on response preparation in task-switching behavior
    Karsten Witt
    Department of Neurology, University Medical Center Schleswig Holstein Campus Kiel, Schittenhelmstrasse 10, D 24105 Kiel, Germany
    Brain Res 1114:173-82. 2006
    ..This argues for different mechanisms that underlie the changes in task-switching behavior in healthy aging and PD...
  50. doi request reprint Risk factors for executive dysfunction after subthalamic nucleus stimulation in Parkinson's disease
    Christine Daniels
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 25:1583-9. 2010
    ....
  51. ncbi request reprint Differential effects of L-dopa and subthalamic stimulation on depressive symptoms and hedonic tone in Parkinson's disease
    Karsten Witt
    Department of Neurology, University Schleswig Holstein, Kiel, Germany
    J Neuropsychiatry Clin Neurosci 18:397-401. 2006
    ..These results demonstrate a single dissociation of depressive symptoms and anhedonia in response to an acute L-dopa and STN-stimulation challenge...
  52. doi request reprint Cortical correlates of the basic and first harmonic frequency of Parkinsonian tremor
    Jan Raethjen
    Department of Neurology, University of Kiel, Schittenhelmstr 10, 24105 Kiel, Germany
    Clin Neurophysiol 120:1866-72. 2009
    ..It has been hypothesized that the basic and first harmonic frequency of Parkinsonian tremor are somewhat independent oscillations the biological basis of which remains unclear...
  53. doi request reprint Inducing homeostatic-like plasticity in human motor cortex through converging corticocortical inputs
    Monika Pötter-Nerger
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    J Neurophysiol 102:3180-90. 2009
    ..These results provide evidence for a homeostatic response pattern in the human M1(HAND) that integrates acute plastic changes evoked through different "input channels."..
  54. ncbi request reprint Two different pathogenetic mechanisms in psychogenic tremor
    J Raethjen
    Department of Neurology, University of Kiel, Germany
    Neurology 63:812-5. 2004
    ..But some patients have tremor ongoing during their waking time which is unlikely to be produced voluntarily. Therefore, nonvoluntary physiologic oscillatory mechanisms must be considered...
  55. ncbi request reprint Most effective stimulation site in subthalamic deep brain stimulation for Parkinson's disease
    Jan Herzog
    Department of Neurology, Christian Albrechts Universitat Kiel, Germany
    Mov Disord 19:1050-4. 2004
    ..g., zona incerta, were significantly less effective. We suggest that the dorsolateral STN border should be covered by STN-DBS...
  56. doi request reprint Effect of cabergoline on parkinsonian tremor assessed by long-term actigraphy
    Sabine Binder
    Department of Neurology, Universitatsklinikum Schleswig Holstein, Campus Kiel, Schittenhelmstrasse 10, Kiel, Germany
    Eur Neurol 61:149-53. 2009
    ..One reason is the substantial fluctuation of tremor severity over time, which is difficult to capture and may render momentary clinical assessments unreliable...
  57. ncbi request reprint Two-year follow-up of subthalamic deep brain stimulation in Parkinson's disease
    Jan Herzog
    Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
    Mov Disord 18:1332-7. 2003
    ..The current series demonstrates efficacy and safety of STN-DBS beyond the first year after surgical procedure. Complications of STN-DBS comprise a wide range of psychiatric adverse events which, however, were temporary...
  58. doi request reprint Acquired stuttering after pallidal deep brain stimulation for dystonia
    Adelheid Nebel
    Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
    J Neural Transm 116:167-9. 2009
    ..This emphasizes a role of the sensorimotor part of the internal globus pallidus in regulating speech fluency...
  59. ncbi request reprint Effect of subthalamic deep brain stimulation on the function of the urinary bladder
    Christoph Seif
    Department of Urology, Christian Albrechts Universitat Kiel, Kiel, Germany
    Ann Neurol 55:118-20. 2004
    ..In a series of 16 patients, we demonstrated that subthalamic deep brain stimulation has a significant and urodynamically recordable effect leading to a normalization of pathologically increased bladder sensibility...
  60. ncbi request reprint Improved sensory gating of urinary bladder afferents in Parkinson's disease following subthalamic stimulation
    Jan Herzog
    Department of Neurology, Christian Albrechts University Kiel, Schittenhelmstrasse 10, 24105 Kiel, Germany
    Brain 131:132-45. 2008
    ..Furthermore, this is the first imaging study, which shows an effect of STN-DBS on sensory gating in PD patients and its neural basis...
  61. ncbi request reprint Deep brain stimulation in late stage Parkinson's disease: a retrospective cost analysis in Germany
    Wassilios Meissner
    Department of Neurology, Charite Campus Virchow Klinikum, Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
    J Neurol 252:218-23. 2005
    ..The present study provides first data of an important number of patients on clinical effectiveness and expenses in relation to STNDBS...
  62. ncbi request reprint Pallidal stimulation for dystonia
    Martin Krause
    Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany
    Neurosurgery 55:1361-8; discussion 1368-70. 2004
    ..Yet only few studies have been published to date regarding this treatment. We present the results of DBS of the GPi in 17 patients with severe dystonia of different causes...
  63. doi request reprint Camptocormia in idiopathic Parkinson's disease: a focal myopathy of the paravertebral muscles
    Nils G Margraf
    Department of Neurology, University Hospital Schleswig Holstein, Campus Kiel, Germany
    Mov Disord 25:542-51. 2010
    ..The cause of camptocormia in idiopathic PD is a focal myopathy. Our findings suggest that the myopathy has a progressive course, which finally leads to degeneration of the paravertebral muscles...
  64. doi request reprint Deep brain stimulation in Parkinson's disease following fetal nigral transplantation
    Jan Herzog
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 23:1293-6. 2008
    ..These findings, based on two case reports, highlight the pivotal role of the GPi in mediating dyskinesia-related neural activity within the basal ganglia loop...
  65. ncbi request reprint Long-term benefit to pallidal deep brain stimulation in a case of dystonia secondary to pantothenate kinase-associated neurodegeneration
    Martin Krause
    Department of Neurology, Ruprecht Krals University, INF 400, Heidelberg, Germany
    Mov Disord 21:2255-7. 2006
    ..The impact of DBS on the progression and life expectancy in PKAN is unknown. We present a 5-year outcome and video documentation of bilateral GPi-DBS of an adolescent patient suffering from genetically defined PKAN...
  66. doi request reprint ATP13A2 variants in early-onset Parkinson's disease patients and controls
    Ana Djarmati
    Department of Neurology, University of Lubeck, Lubeck, Germany
    Mov Disord 24:2104-11. 2009
    ..Although heterozygous variants are present in a considerable number of patients, they are-based on this relatively small sample-not significantly more frequent in patients compared to controls...
  67. ncbi request reprint Praying-induced oromandibular dystonia
    Tihomir V Ilic
    Department of Neurology, Christian Albrechts University of Kiel, Kiel, Germany
    Mov Disord 20:385-6. 2005
    ..His speech was affected exclusively while reciting Islamic prayers in Arabic language, which he otherwise did not speak...
  68. ncbi request reprint Pallidal deep-brain stimulation in primary generalized or segmental dystonia
    Andreas Kupsch
    Charite Universitatsmedizin Berlin, Campus Virchow, Berlin, Germany
    N Engl J Med 355:1978-90. 2006
    ..Neurostimulation of the internal globus pallidus has been shown to be effective in reducing symptoms of primary dystonia. We compared this surgical treatment with sham stimulation in a randomized, controlled clinical trial...
  69. ncbi request reprint Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: results from a prospective, randomized sham-controlled trial
    Joerg Mueller
    Mov Disord 23:131-4. 2008
    ..The open-label extension phase resulted in a significant improvement in all SF-36 domains following 6 months of neurostimulation. These results demonstrate a favorable impact of DBS on HRQoL in primary dystonia...
  70. ncbi request reprint Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position
    Jurgen Voges
    Department of Stereotactic and Functional Neurosurgery, University of Cologne, Germany
    J Neurosurg 96:269-79. 2002
    ..The goal of this study was to relate the degree of clinical improvement and that of energy consumption to the anatomical position of electrode poles used for long-term stimulation...
  71. ncbi request reprint Deep brain stimulation of the subthalamic nucleus enhances emotional processing in Parkinson disease
    Frank Schneider
    Department of Psychiatry and Psychotherapy, University of Dusseldorf, Germany
    Arch Gen Psychiatry 60:296-302. 2003
    ..Clinical observations indicate additional influence on emotional behavior...
  72. ncbi request reprint Dementia in idiopathic Parkinson's syndrome
    Gerd A Fuchs
    Parkinson Clinic Wolfach, Kreuzbergstr 12 24, 77709 Wolfach, Germany
    J Neurol 251:VI/28-32. 2004
    ..The demented Parkinsonian patients then present with improvement in cognitive function while motor skills do not deteriorate...
  73. ncbi request reprint Premutations in the FMR1 gene as a modifying factor in Parkin-associated Parkinson's disease?
    Katja Hedrich
    Department of Human Genetics, University of Lubeck, Lubeck, Germany
    Mov Disord 20:1060-2. 2005
    ..Of note, 1 of the affected premutation carriers had a heterozygous Parkin mutation...
  74. ncbi request reprint [Non-medical neurosurgical Parkinson treatment]
    Jan Herzog
    Neurologische Klinik der Christian Albrechts Universität, Kiel
    Pharm Unserer Zeit 35:234-40. 2006
  75. ncbi request reprint Managing Parkinson's disease with continuous dopaminergic stimulation
    Erik Wolters
    Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    CNS Spectr 13:1-14; quiz 15-6. 2008
    ..Jens Volkmann, MD, discusses selection criteria for STN DBS and duodenal L-dopa/carbidopa infusion. Teus van Laar, MD, PhD, and Ad Hovestadt, MD, discuss the first data from a Dutch cohort study of duodenal L-dopa/carbidopa...
  76. ncbi request reprint Depression and Parkinson's disease
    Matthias R Lemke
    Rhine Clinic Bonn, Kaiser Karl Ring 20, 53111 Bonn, Germany
    J Neurol 251:VI/24-7. 2004
    ..New dopamine agonists pramipexole and ropinirole appear to ameliorate depressive symptoms in PD in addition to effects on motor symptoms. There is a lack of appropriate rating scales and controlled studies regarding depression in PD...