Andreas Vilcinskas

Summary

Affiliation: University of Giessen
Country: Germany

Publications

  1. pmc Development and immunity-related microRNAs of the lepidopteran model host Galleria mellonella
    Krishnendu Mukherjee
    Fraunhofer Institute for Molecular Biology and Applied Ecology, Department of Bioresources, Winchester Str, 2, 35395 Giessen, Germany
    BMC Genomics 15:705. 2014
  2. pmc A switch from constitutive chemical defence to inducible innate immune responses in the invasive ladybird Harmonia axyridis
    Henrike Schmidtberg
    Department Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Winchesterstrasse 2, 35394 Giessen, Germany
    Biol Lett 9:20130006. 2013
  3. doi request reprint Response to comments on "Invasive harlequin ladybird carries biological weapons against native competitors"
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Heinrich Buff Ring 26 32, Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Science 341:1342. 2013
  4. doi request reprint Invasive harlequin ladybird carries biological weapons against native competitors
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Heinrich Buff Ring 26 32, Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Science 340:862-3. 2013
  5. doi request reprint Evolutionary plasticity of insect immunity
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    J Insect Physiol 59:123-9. 2013
  6. pmc Expansion of the antimicrobial peptide repertoire in the invasive ladybird Harmonia axyridis
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Justus Liebig University, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Proc Biol Sci 280:20122113. 2013
  7. pmc Histone acetylation mediates epigenetic regulation of transcriptional reprogramming in insects during metamorphosis, wounding and infection
    Krishnendu Mukherjee
    Department of Bioresources, Fraunhofer Institute of Molecular Biology and Applied Ecology, Winchester Str, 2, Giessen, 35395, Germany
    Front Zool 9:25. 2012
  8. pmc Immunity and other defenses in pea aphids, Acyrthosiphon pisum
    Nicole M Gerardo
    Department of Biology, Emory University, O Wayne Rollins Research Center, 1510 E, Clifton Road NE, Atlanta, GA 30322, USA
    Genome Biol 11:R21. 2010
  9. ncbi request reprint Anti-infective therapeutics from the Lepidopteran model host Galleria mellonella
    Andreas Vilcinskas
    Fraunhofer Institute of Molecular Biology and Applied Ecology, Department of Bio resources, Giessen, Germany
    Curr Pharm Des 17:1240-5. 2011
  10. doi request reprint Coevolution between pathogen-derived proteinases and proteinase inhibitors of host insects
    Andreas Vilcinskas
    Justus Liebig University of Giessen, Institute of Phytopathology and Applied Zoology at the Interdisciplinary Research Center, Giessen, Germany
    Virulence 1:206-14. 2010

Collaborators

Detail Information

Publications56

  1. pmc Development and immunity-related microRNAs of the lepidopteran model host Galleria mellonella
    Krishnendu Mukherjee
    Fraunhofer Institute for Molecular Biology and Applied Ecology, Department of Bioresources, Winchester Str, 2, 35395 Giessen, Germany
    BMC Genomics 15:705. 2014
    ..mellonella transcriptome, here we describe the identification and analysis of development and immunity-related miRNAs, thus providing valuable additional data to promote the use of this model host for the analysis of complex processes...
  2. pmc A switch from constitutive chemical defence to inducible innate immune responses in the invasive ladybird Harmonia axyridis
    Henrike Schmidtberg
    Department Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Winchesterstrasse 2, 35394 Giessen, Germany
    Biol Lett 9:20130006. 2013
    ..These alternative antimicrobial defence mechanisms may reflect a trade-off resulting from fitness-related costs associated with the simultaneous synthesis of harmonine and antimicrobial peptides/proteins...
  3. doi request reprint Response to comments on "Invasive harlequin ladybird carries biological weapons against native competitors"
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Heinrich Buff Ring 26 32, Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Science 341:1342. 2013
    ..We contend that there is abundant evidence that native ladybirds feed on H. axyridis eggs and that interspecific microsporidial transfer is a common phenomenon, supporting the proposed role of these parasites as biological weapons. ..
  4. doi request reprint Invasive harlequin ladybird carries biological weapons against native competitors
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Heinrich Buff Ring 26 32, Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Science 340:862-3. 2013
    ....
  5. doi request reprint Evolutionary plasticity of insect immunity
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    J Insect Physiol 59:123-9. 2013
    ....
  6. pmc Expansion of the antimicrobial peptide repertoire in the invasive ladybird Harmonia axyridis
    Andreas Vilcinskas
    Institute of Phytopathology and Applied Zoology, Justus Liebig University, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Proc Biol Sci 280:20122113. 2013
    ..The invasive success of H. axyridis can therefore be attributed at least in part to the greater efficiency of its immune system, particularly the expansion of AMP gene families and their induction in response to pathogens...
  7. pmc Histone acetylation mediates epigenetic regulation of transcriptional reprogramming in insects during metamorphosis, wounding and infection
    Krishnendu Mukherjee
    Department of Bioresources, Fraunhofer Institute of Molecular Biology and Applied Ecology, Winchester Str, 2, Giessen, 35395, Germany
    Front Zool 9:25. 2012
    ..abstract:..
  8. pmc Immunity and other defenses in pea aphids, Acyrthosiphon pisum
    Nicole M Gerardo
    Department of Biology, Emory University, O Wayne Rollins Research Center, 1510 E, Clifton Road NE, Atlanta, GA 30322, USA
    Genome Biol 11:R21. 2010
    ....
  9. ncbi request reprint Anti-infective therapeutics from the Lepidopteran model host Galleria mellonella
    Andreas Vilcinskas
    Fraunhofer Institute of Molecular Biology and Applied Ecology, Department of Bio resources, Giessen, Germany
    Curr Pharm Des 17:1240-5. 2011
    ..The potential and limitations of insect-derived gene-encoded antimicrobial compounds as anti-infective therapeutics are discussed...
  10. doi request reprint Coevolution between pathogen-derived proteinases and proteinase inhibitors of host insects
    Andreas Vilcinskas
    Justus Liebig University of Giessen, Institute of Phytopathology and Applied Zoology at the Interdisciplinary Research Center, Giessen, Germany
    Virulence 1:206-14. 2010
    ....
  11. pmc Analysis of the immune-inducible transcriptome from microbial stress resistant, rat-tailed maggots of the drone fly Eristalis tenax
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Interdisciplinary Research Center, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    BMC Genomics 8:326. 2007
    ..tenax that are induced upon septic injury. Suppression subtractive hybridization was performed to selectively amplify and identify cDNAs that are differentially expressed in response to injected crude bacterial endotoxin (LPS)...
  12. pmc Insect peptide metchnikowin confers on barley a selective capacity for resistance to fungal ascomycetes pathogens
    Mohammad Rahnamaeian
    Institute of Phytopathology and Applied Zoology, Research Centre for BioSystems, Land Use and Nutrition IFZ, Justus Liebig University, D 35392 Giessen, Germany
    J Exp Bot 60:4105-14. 2009
    ....
  13. ncbi request reprint Identification of immune-related genes from an apterygote insect, the firebrat Thermobia domestica
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Interdisciplinary Research Center, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Insect Biochem Mol Biol 37:726-31. 2007
    ..The identified genes implicate the presence of sophisticated regulatory mechanisms in insect immune signaling and give insight into evolutionarily conserved features of insect innate immunity...
  14. pmc MMPs regulate both development and immunity in the tribolium model insect
    Eileen Knorr
    Interdisciplinary Research Center, Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Giessen, Germany
    PLoS ONE 4:e4751. 2009
    ..In spite of previous, intensive investigation in vitro and in cell culture, their pleiotrophic functions in vivo are still not well understood...
  15. pmc Screening the biosphere: the fungicolous fungus Trichoderma phellinicola, a prolific source of hypophellins, new 17-, 18-, 19-, and 20-residue peptaibiotics
    Christian Rene Röhrich
    Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Bioresources Project Group, Winchesterstrasse 2, D 35394 Giessen
    Chem Biodivers 10:787-812. 2013
    ..For the new peptaibiotics produced by T. phellinicola, the name 'hypophellin(s)', based on the teleomorph name, is introduced...
  16. pmc Brain infection and activation of neuronal repair mechanisms by the human pathogen Listeria monocytogenes in the lepidopteran model host Galleria mellonella
    Krishnendu Mukherjee
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Giessen, Germany
    Virulence 4:324-32. 2013
    ..Our data extend the utility of G. mellonella larvae as an ideal model for the high-throughput in vivo testing of potential compounds against listeriosis. ..
  17. ncbi request reprint Identification of a lepidopteran matrix metalloproteinase with dual roles in metamorphosis and innate immunity
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Interdisciplinary Research Center, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Dev Comp Immunol 32:400-9. 2008
    ....
  18. pmc Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity
    Christian Rene Röhrich
    Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Giessen, Germany
    Biol Lett 8:308-11. 2012
    ..Harmonine displays gametocytocidal activity, and inhibits the exflagellation of microgametocytes and zygote formation. In an Anopheles stephensi mosquito feeding model, harmonine displays transmission-blocking activity...
  19. pmc Anti-Listeria activities of Galleria mellonella hemolymph proteins
    Krishnendu Mukherjee
    Institute of Phytopathology and Applied Zoology, Justus Liebig University, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Appl Environ Microbiol 77:4237-40. 2011
    ..We also have shown that specific virulence-associated genes known to mediate antimicrobial resistance of Listeria in mammalian models indicated a similar function in Galleria...
  20. doi request reprint Pathogen-induced release of plant allomone manipulates vector insect behavior
    Christoph J Mayer
    Institute for Phytopathology and Applied Zoology, Justus Liebig University, Giessen, 35392, Germany
    J Chem Ecol 34:1518-22. 2008
    ..picta. Consequently, this new type of infochemical, i.e., a phytopathogen-induced plant allomone, represents a promising compound to develop innovative techniques for monitoring or maybe even mass trapping of C. picta...
  21. ncbi request reprint Beetle immunity: Identification of immune-inducible genes from the model insect Tribolium castaneum
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Dev Comp Immunol 32:585-95. 2008
    ..g. heat-shock proteins) or insecticide resistance (e.g. cytochrome P450s) in Tribolium, suggesting that there may be crosstalk between the immune and stress responses...
  22. doi request reprint Multifunctional weaponry: the chemical defenses of earwigs
    Tina Gasch
    Institute of Phytopathology and Applied Zoology, Justus Liebig University Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany Electronic address
    J Insect Physiol 59:1186-93. 2013
    ..auricularia displayed nematicidal activity against Caenorhabditis elegans. Our data support the hypothesis that earwig secretions are multifunctional, serving both to deter predators and sanitize the microenvironment. ..
  23. ncbi request reprint The insect metalloproteinase inhibitor gene of the lepidopteran Galleria mellonella encodes two distinct inhibitors
    Marianne Wedde
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Biol Chem 388:119-27. 2007
    ....
  24. doi request reprint Identification of collagen IV derived danger/alarm signals in insect immunity by nanoLC-FTICR MS
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Biol Chem 390:1303-11. 2009
    ..Further examination using specific MAP kinase inhibitors indicated that MEK/ERK and p38 are involved in RGD/E-mediated immune-signaling pathways, whereas JNK seems to play only a minor role...
  25. pmc Galleria mellonella as a model system for studying Listeria pathogenesis
    Krishnendu Mukherjee
    Institute for Phytopathology and Applied Zoology, Justus Liebig University, Frankfurter Strasse 107, 35392 Giessen, Germany
    Appl Environ Microbiol 76:310-7. 2010
    ..isolated from a wide variety of settings from both the clinic and the environment...
  26. doi request reprint The sequences of the eleven-residue peptaibiotics: suzukacillins-B
    Christian Rene Röhrich
    Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Bioresources Project Group, Winchesterstrasse 2, D 35394 Giessen
    Chem Biodivers 10:827-37. 2013
    ..One peptide contains a C-terminal residue of yet undetermined structure. Comparison with previously reported eleven-residue peptaibol sequences reveals that eight of the peptides represent new sequence analogs...
  27. doi request reprint Insect antenna-based biosensors for in situ detection of volatiles
    Matthias Schott
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 39592, Giessen, Germany
    Adv Biochem Eng Biotechnol 136:101-22. 2013
    ..We also consider the use of these applications in portable devices outside the laboratory under field conditions...
  28. doi request reprint Tribolium castaneum as a model for high-throughput RNAi screening
    Eileen Knorr
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 39592, Giessen, Germany
    Adv Biochem Eng Biotechnol 136:163-78. 2013
    ..The T. castaneum screening platform offers a system for discovery of candidate genes with high potential benefit...
  29. pmc Homoserine lactones influence the reaction of plants to rhizobia
    Azhar A Zarkani
    Institute of Phytopathology and Applied Zoology, Centre for BioSystems, Land Use and Nutrition, Justus Liebig University Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Int J Mol Sci 14:17122-46. 2013
    ..In addition, plants seem to influence the availability of AHLs in the rhizosphere. Taken together, this report provides new insights in the role of N-acyl-homoserine lactones in the inter-kingdom communication at the root surface...
  30. pmc Microbial metalloproteinases mediate sensing of invading pathogens and activate innate immune responses in the lepidopteran model host Galleria mellonella
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Infect Immun 75:175-83. 2007
    ..mellonella. The obtained results support the proposed danger model, which suggests that the immune system senses endogenous alarm signals during infection besides recognition of microbial pattern molecules...
  31. pmc A comprehensive transcriptome and immune-gene repertoire of the lepidopteran model host Galleria mellonella
    Heiko Vogel
    Institute of Phytopathology and Applied Zoology, University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    BMC Genomics 12:308. 2011
    ..In order to compensate for the lack of genomic information in Galleria, we subjected the transcriptome of different developmental stages and immune-challenged larvae to next generation sequencing...
  32. doi request reprint Post-embryonic functions of HSP90 in Tribolium castaneum include the regulation of compound eye development
    Eileen Knorr
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Dev Genes Evol 221:357-62. 2011
    ..Our results suggest that HSP90 functions can be expanded beyond the known ones in insect embryogenesis to include roles in post-embryonic development such as the regulation of compound eye development...
  33. ncbi request reprint Host-derived extracellular nucleic acids enhance innate immune responses, induce coagulation, and prolong survival upon infection in insects
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, Giessen, Germany
    J Immunol 181:2705-12. 2008
    ....
  34. pmc Gender- and stressor-specific microRNA expression in Tribolium castaneum
    Dalial Freitak
    Institute for Phytopathology and Applied Entomology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Biol Lett 8:860-3. 2012
    ..Our results suggest that Tribolium males and females display differential regulatory elements, both pre- and post-transcriptional, likely resulting from different investment strategies in life-history traits...
  35. doi request reprint Optimization of insect cell based protein production processes - online monitoring, expression systems, scale up
    Damir Druzinec
    Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Giessen, Germany
    Adv Biochem Eng Biotechnol 136:65-100. 2013
    ..Since scale up of production processes is one of the most critical steps in process development, a conclusive overview is given about scale up aspects for industrial insect cell culture processes...
  36. pmc High-resolution mass spectrometry driven discovery of peptidic danger signals in insect immunity
    Arton Berisha
    Institute of Inorganic and Analytical Chemistry, Justus Liebig University, Giessen, Germany
    PLoS ONE 8:e80406. 2013
    ..Consequently, our study indicates that the danger model also plays a role in insect immunity. ..
  37. doi request reprint A portable gas chromatograph with simultaneous detection by mass spectrometry and electroantennography for the highly sensitive in situ measurement of volatiles
    Matthias Schott
    Institute of Phytopathology and Applied Zoology, Justus Liebig University Giessen, Heinrich Buff Ring 26 32, 35392, Giessen, Germany
    Anal Bioanal Chem 405:7457-67. 2013
    ..Our data confirm that the instrument generates highly reproducible results and is highly sensitive, with a detection threshold of 3 ng/m(3) (E,Z)-7,9-dodecadienyl acetate in outside air. ..
  38. doi request reprint Protected by fumigants: beetle perfumes in antimicrobial defense
    Jürgen Gross
    Institute of Phytopathology and Applied Zoology, Justus Liebig University Giessen, Heinrich Buff Ring 26 32, Giessen, Germany
    J Chem Ecol 34:179-88. 2008
    ....
  39. doi request reprint Phytopathogen lures its insect vector by altering host plant odor
    Christoph J Mayer
    Institute for Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Giessen, 35392, Germany
    J Chem Ecol 34:1045-9. 2008
    ..These results suggest that the pathogen modifies host plant odor that lures its vector to infected plants. This may result in higher numbers of transmitting vector insects within the population...
  40. pmc Metabolite localization by atmospheric pressure high-resolution scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging in whole-body sections and individual organs of the rove beetle Paederus riparius
    Dhaka Ram Bhandari
    Institute of Inorganic and Analytical Chemistry, Justus Liebig University Giessen, Schubertstraße 60, Building 16, 35392, Giessen, Germany
    Anal Bioanal Chem 407:2189-201. 2015
    ..Without any labeling, we assigned key lipids for specific organs to describe their location in the body and to identify morphological structures with a specificity higher than with staining or immunohistology methods. ..
  41. doi request reprint Peptaibol, Secondary-Metabolite, and Hydrophobin Pattern of Commercial Biocontrol Agents Formulated with Species of the Trichoderma harzianum Complex
    Thomas Degenkolb
    Interdisciplinary Research Centre for Biosystems, Land Use and Nutrition IFZ, Department of Food Sciences, Institute of Nutritional Science, University of Giessen, Heinrich Buff Ring 26 32, DE 35392 Giessen Present address Interdisciplinary Research Centre for BioSystems, Land Use and Nutrition IFZ, Department of Applied Entomology, Institute of Phytopathology and Applied Zoology IPAZ, University of Giessen, Heinrich Buff Ring 26 32, DE 35392 Giessen phone 49 641 99 37651, fax 49 641 99 37609
    Chem Biodivers 12:662-84. 2015
    ..Notably, none of the isolates produced low-molecular weight mycotoxins. ..
  42. pmc Antimicrobial Peptides Expressed in Medicinal Maggots of the Blow Fly Lucilia sericata Show Combinatorial Activity against Bacteria
    Anne Kathrin Pöppel
    Fraunhofer Institute for Molecular Biology and Applied Ecology, Department of Bioresources, Giessen, Germany
    Antimicrob Agents Chemother 59:2508-14. 2015
    ..The AMPs that are easy to synthesize are currently being produced in bulk to allow their evaluation as novel anti-infectives that can be formulated in hydrogels to produce therapeutic wound dressings and adhesive bandages. ..
  43. doi request reprint Identification of immune inducible genes from the velvet worm Epiperipatus biolleyi (Onychophora)
    Boran Altincicek
    Interdisciplinary Research Center, Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Dev Comp Immunol 32:1416-21. 2008
    ....
  44. doi request reprint Two c-type lysozymes boost the innate immune system of the invasive ladybird Harmonia axyridis
    Annika Beckert
    Department of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Strasse 2, 35394 Gießen, Germany Institute for Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Dev Comp Immunol 49:303-12. 2015
    ..Our results suggest that two structurally and functionally distinct lysozymes contribute to innate immune responses of H.axyridis and augment the harmonine and AMP components of the immune response...
  45. doi request reprint Hypopulvins, novel peptaibiotics from the polyporicolous fungus Hypocrea pulvinata, are produced during infection of its natural hosts
    Christian Rene Röhrich
    Fraunhofer Institute for Molecular Biology and Applied Ecology, Bioresources Project Group, Winchesterstraße 2, 35394 Giessen, Germany
    Fungal Biol 116:1219-31. 2012
    ....
  46. doi request reprint Galleria mellonella as a model host to study gut microbe homeostasis and brain infection by the human pathogen listeria monocytogenes
    Krishnendu Mukherjee
    Department of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Str 2, 35395, Giessen, Germany
    Adv Biochem Eng Biotechnol 135:27-39. 2013
    ..We also discuss the current uses of G. mellonella as a model to develop therapeutic strategies against listeriosis. ..
  47. doi request reprint On-site airborne pheromone sensing
    Christoph Wehrenfennig
    Institute of Applied Physics, JLU Giessen, Giessen, Germany
    Anal Bioanal Chem 405:6389-403. 2013
    ..Furthermore, the infochemical effect describing the anthropogenic contamination of the ecosystem through semiochemicals, will be considered in the context of novel on-site pheromone sensing-systems. ..
  48. doi request reprint Secondary metabolites released by the burying beetle Nicrophorus vespilloides: chemical analyses and possible ecological functions
    Thomas Degenkolb
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Giessen, Germany
    J Chem Ecol 37:724-35. 2011
    ..We discuss the ecological relevance of these compounds with respect to both their antimicrobial activity and ecological relevance...
  49. doi request reprint The structural sheath protein of aphids is required for phloem feeding
    Torsten Will
    Institute for Phytopathology and Applied Zoology, Justus Liebig University Giessen, Heinrich Buff Ring 26 32, D 35392, Giessen, Germany
    Insect Biochem Mol Biol 57:34-40. 2015
    ..The SHP is present in several aphid species and silencing has a similar impact to aphid-resistant plants, suggesting that SHP is an excellent target for RNAi-mediated pest control. ..
  50. doi request reprint The chemical defense in larvae of the earwig Forficula auricularia
    Tina Gasch
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Giessen, Germany
    J Insect Physiol 67:1-8. 2014
    ..rubra, however, it does not discourage feeding in spiders. Our results suggest that earwigs use different glands during ontogenesis to produce secretions that play roles in chemical defense against predators such as ants. ..
  51. doi request reprint Aphid-proof plants: biotechnology-based approaches for aphid control
    Torsten Will
    Department of Phytopathology and Applied Zoology, Justus Liebig University Giessen, Heinrich Buff Ring 26 32, 35392, Giessen, Germany
    Adv Biochem Eng Biotechnol 136:179-203. 2013
    ..The results from several different studies suggest that biotechnology-based approaches offer a promising strategy for aphid control. ..
  52. pmc Methods to identify enzymes that degrade the main extracellular polysaccharide component of Staphylococcus epidermidis biofilms
    Anke Gökçen
    Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Giesen, Germany
    Virulence 4:260-70. 2013
    ..We validated our procedures using dispersin B, which is currently the only known PNAG-degrading enzyme...
  53. ncbi request reprint Transgenic expression of gallerimycin, a novel antifungal insect defensin from the greater wax moth Galleria mellonella, confers resistance to pathogenic fungi in tobacco
    Gregor Langen
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Biol Chem 387:549-57. 2006
    ..The feasibility of the use of gallerimycin to counteract fungal diseases in crop plants is discussed...
  54. pmc Comparative analysis of septic injury-inducible genes in phylogenetically distant model organisms of regeneration and stem cell research, the planarian Schmidtea mediterranea and the cnidarian Hydra vulgaris
    Boran Altincicek
    Interdisciplinary Research Center, Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
    Front Zool 5:6. 2008
    ....
  55. ncbi request reprint Metamorphosis and collagen-IV-fragments stimulate innate immune response in the greater wax moth, Galleria mellonella
    Boran Altincicek
    Institute of Phytopathology and Applied Zoology, Justus Liebig University of Giessen, Heinrich Buff Ring 26 32, 35392 Giessen, Germany
    Dev Comp Immunol 30:1108-18. 2006
    ....
  56. doi request reprint Antimicrobial peptides: the ancient arm of the human immune system
    Jochen Wiesner
    Justus Liebig University of Giessen, Institute of Phytopathology and Applied Zoology at the Interdisciplinary Research Center, Giessen, Germany
    Virulence 1:440-64. 2010
    ..Omiganan, representing an indolicidin derivative, has been demonstrated to be effective in the treatment of acne and catheter-related local infections and is currently considered to be the most promising AMP-based drug candidate...