Michael Vieth

Summary

Affiliation: University of Bayreuth
Country: Germany

Publications

  1. ncbi request reprint Adenocarcinoma in an ileal pouch after prior proctocolectomy for carcinoma in a patient with ulcerative pancolitis
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth, Germany
    Virchows Arch 433:281-4. 1998
  2. ncbi request reprint Fundic gland polyps are not induced by proton pump inhibitor therapy
    M Vieth
    Institute of Pathology, Bayreuth Clinic, Germany
    Am J Clin Pathol 116:716-20. 2001
  3. ncbi request reprint What parameters are relevant for the histological diagnosis of gastroesophageal reflux disease without Barrett's mucosa?
    M Vieth
    Institute of Pathology, Otto von Guericke University, Magdeburg, Germany
    Dig Dis 22:196-201. 2004
  4. ncbi request reprint Detection of non-pylori Helicobacter species in "Helicobacter heilmannii"-infected humans
    Dominic De Groote
    Technology Transfer Office, Ghent University, Lammerstraat 35, B 9000 Ghent, Belgium
    Helicobacter 10:398-406. 2005
  5. ncbi request reprint Prevalence of Barrett's esophagus in the general population: an endoscopic study
    Jukka Ronkainen
    Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden
    Gastroenterology 129:1825-31. 2005
  6. pmc Liver-intestine-cadherin is a sensitive marker of intestinal differentiation during Barrett's carcinogenesis
    Anna Mokrowiecka
    Department of Digestive Tract Diseases, Medical University of Lodz, Str Kopcinskiego 22, 90 153, Lodz, Poland
    Dig Dis Sci 58:699-705. 2013
  7. pmc Pyloric gland adenoma of the cystic duct with malignant transformation: report of a case with a review of the literature
    Inga Marie Schaefer
    Department of Pathology, University Medical Center Gottingen, Robert Koch Straße 40, Gottingen, D 37075, Germany
    BMC Cancer 12:570. 2012
  8. ncbi request reprint European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Annotations of colorectal lesions
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Endoscopy 44:SE131-9. 2012
  9. doi request reprint Barrett's esophagus. Practical issues for daily routine diagnosis
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzerstr 101, Bayreuth, Germany
    Pathol Res Pract 208:261-8. 2012
  10. pmc Quality assurance in pathology in colorectal cancer screening and diagnosis—European recommendations
    Phil Quirke
    Pathology and Tumour Biology, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK
    Virchows Arch 458:1-19. 2011

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Adenocarcinoma in an ileal pouch after prior proctocolectomy for carcinoma in a patient with ulcerative pancolitis
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth, Germany
    Virchows Arch 433:281-4. 1998
    ..Adenocarcinoma arising in an ileoanal reservoir is rare. Two other cases have been reported: both patients concerned were believed to have developed cancer in small areas of residual remaining rectal mucosa...
  2. ncbi request reprint Fundic gland polyps are not induced by proton pump inhibitor therapy
    M Vieth
    Institute of Pathology, Bayreuth Clinic, Germany
    Am J Clin Pathol 116:716-20. 2001
    ..2% in the PPI group). No significant differences were present between the groups with respect to the presence of gastritis or age or sex. Our study shows that a causal pathogenetic relationship between PPI therapy and FGPs is unlikely...
  3. ncbi request reprint What parameters are relevant for the histological diagnosis of gastroesophageal reflux disease without Barrett's mucosa?
    M Vieth
    Institute of Pathology, Otto von Guericke University, Magdeburg, Germany
    Dig Dis 22:196-201. 2004
    ..The aim of the present analysis was to relate histological changes of the esophageal squamous epithelium to different severities of GERD...
  4. ncbi request reprint Detection of non-pylori Helicobacter species in "Helicobacter heilmannii"-infected humans
    Dominic De Groote
    Technology Transfer Office, Ghent University, Lammerstraat 35, B 9000 Ghent, Belgium
    Helicobacter 10:398-406. 2005
    ..It was the aim of the present study to assess the presence of animal Helicobacter species and H. pylori in humans infected with HHLO, as diagnosed by histology...
  5. ncbi request reprint Prevalence of Barrett's esophagus in the general population: an endoscopic study
    Jukka Ronkainen
    Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden
    Gastroenterology 129:1825-31. 2005
    ..The prevalence of BE in the general population is uncertain because upper endoscopy is required for diagnosis. This study aimed to determine the prevalence of BE and possible associated risk factors in an adult Swedish population...
  6. pmc Liver-intestine-cadherin is a sensitive marker of intestinal differentiation during Barrett's carcinogenesis
    Anna Mokrowiecka
    Department of Digestive Tract Diseases, Medical University of Lodz, Str Kopcinskiego 22, 90 153, Lodz, Poland
    Dig Dis Sci 58:699-705. 2013
    ..Liver-intestine (LI)-cadherin, an intestine-specific marker, is involved in intestinal metaplasia development in gastric and colon cancers and could be of value in diagnosis and differentiation...
  7. pmc Pyloric gland adenoma of the cystic duct with malignant transformation: report of a case with a review of the literature
    Inga Marie Schaefer
    Department of Pathology, University Medical Center Gottingen, Robert Koch Straße 40, Gottingen, D 37075, Germany
    BMC Cancer 12:570. 2012
    ..5 cm and a mean age of occurrence around 70 years. Adenocarcinoma develops in about 40% of cases and may be difficult to detect due to relatively mild nuclear atypia...
  8. ncbi request reprint European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Annotations of colorectal lesions
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Endoscopy 44:SE131-9. 2012
    ..The content of the annex is presented here to promote international discussion and collaboration by making the issues discussed in the guidelines known to a wider professional and scientific community...
  9. doi request reprint Barrett's esophagus. Practical issues for daily routine diagnosis
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzerstr 101, Bayreuth, Germany
    Pathol Res Pract 208:261-8. 2012
    ....
  10. pmc Quality assurance in pathology in colorectal cancer screening and diagnosis—European recommendations
    Phil Quirke
    Pathology and Tumour Biology, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK
    Virchows Arch 458:1-19. 2011
    ....
  11. pmc Identification of novel cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo
    Anna K Walduck
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    Mol Cancer 8:22. 2009
    ..The aim of this study was to identify novel genes down-stream of Cox-2 in an in vivo model, thereby identifying potential targets for the study of the role of Cox- 2 in H. pylori pathogenesis and the initiation of pre- cancerous changes...
  12. pmc DNA copy number profiles of gastric cancer precursor lesions
    Tineke E Buffart
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    BMC Genomics 8:345. 2007
    ..e. intestinal-type and pyloric gland adenomas, would carry different patterns of DNA copy number changes, possibly reflecting distinct genetic pathways of gastric carcinogenesis in these two adenoma types...
  13. ncbi request reprint New pieces of the pathogenetic mosaic in inflammatory bowel disease
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Eur J Gastroenterol Hepatol 18:123-4. 2006
    ....
  14. doi request reprint Contribution of histology to the diagnosis of reflux disease
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzer Strasse 101, 95445 Bayreuth, Germany
    Best Pract Res Clin Gastroenterol 22:625-38. 2008
    ..However, histology can deliver much more information than the diagnosis of reflux induced lesions (e.g. the exclusion of malignancy or other oesophageal diseases)...
  15. ncbi request reprint Pathology of early upper GI cancers
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzer Str 101, 95445 Bayreuth, Germany
    Best Pract Res Clin Gastroenterol 19:857-69. 2005
    ..Diagnosis of low-grade intraepithelial neoplasia is often confused with regenerative changes. Histological diagnoses of early neoplasms are not the same worldwide and consensus should be improved further...
  16. ncbi request reprint Frequency of Barrett's neoplasia after initial negative endoscopy with biopsy: a long-term histopathological follow-up study
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Endoscopy 38:1201-5. 2006
    ..Barrett's adenocarcinoma is being diagnosed increasingly. We examine possible differences between long segment and short-segment Barrett esophagus (LSBE and SSBE) in long-term follow-up on the basis of our histopathology registry...
  17. ncbi request reprint [Gastritis from a histological point of view]
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth, Preuschwitzer Strasse 101, 95 445 Bayreuth, Germany
    Internist (Berl) 47:578, 580-7. 2006
    ..If less than these four (minimal standard) biopsies are taken, the histological diagnosis will remain uncertain...
  18. ncbi request reprint Pyloric gland adenoma-- how to diagnose?
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Germany
    Cesk Patol 42:4-7. 2006
    ..These cases represent for the most well differentiated early adenocarcinomas which are known to have an excellent prognosis after complete polypectomy and limitation to the mucosal layer...
  19. ncbi request reprint [NSAID-colonopathy]
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth GmbH, Preuschwitzer Strasse 101, 95445 Bayreuth
    Pathologe 27:65-72. 2006
    ..Sometimes NSAID/ASA induced lesions are misdiagnosed as Crohn's disease due to the focal character of the lesions. Since all of our analyses are retrospective, the criteria developed by our group should be checked prospectively...
  20. ncbi request reprint Histological effects of esomeprazole therapy on the squamous epithelium of the distal oesophagus
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Aliment Pharmacol Ther 23:313-9. 2006
    ..Proton pump inhibitor therapy has been reported to reduce proliferative changes of the oesophagus significantly in gastro-oesophageal reflux disease (GERD)...
  21. doi request reprint Structural abnormalities of endoscopy-negative reflux disease--real or perceived?
    Michael Vieth
    Institut fur Pathologie, Klinikum Bayreuth, Bayreuth, Deutschland
    Digestion 78:24-30. 2008
    ..All changes are reversible with PPI therapy. In conclusion, structural abnormalities are not specific for gastroesophageal reflux disease or NERD but are reversible with PPI, which underlines their relevance...
  22. ncbi request reprint Helicobacter pylori infection: protection against Barrett's mucosa and neoplasia?
    M Vieth
    Institute of Pathology, Bayreuth, Germany
    Digestion 62:225-31. 2000
    ....
  23. ncbi request reprint Acute measles gastric infection
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth, Germany
    Am J Surg Pathol 25:259-62. 2001
    ..Our case report confirms the systemic character of measles virus infection and confirms that measles viral replication can involve the gastric mucosa in addition to the conjunctiva, lung, and intestina...
  24. ncbi request reprint [50 years of Barrett esophagus. Current diagnostic possibilities in pathology]
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth, 95445 Bayreuth
    Pathologe 22:62-71. 2001
    ..The gold standard is careful endoscopy and biopsy taking with good documentation of the endoscopical findings and most important still the routine H&E stain are the only reliable diagnostic tools...
  25. ncbi request reprint Red streaks in the oesophagus in patients with reflux disease: is there a histomorphological correlate?
    M Vieth
    Institute of Pathology, Bayreuth, Germany
    Scand J Gastroenterol 36:1123-7. 2001
    ..This study evaluates the histopathology of these red streaks...
  26. pmc Annex to Quirke et al. Quality assurance in pathology in colorectal cancer screening and diagnosis: annotations of colorectal lesions
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzerstr 101, 95445 Bayreuth, Germany
    Virchows Arch 458:21-30. 2011
    ..It is presented here to make the relevant discussion known to a wider scientific audience...
  27. doi request reprint Immunohistochemical analysis of pyloric gland adenomas using a series of Mucin 2, Mucin 5AC, Mucin 6, CD10, Ki67 and p53
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Germany
    Virchows Arch 457:529-36. 2010
    ..The high frequency of malignant transformation of PGA underlines its high potential for invasive malignancy...
  28. doi request reprint [Pseudoneoplastic regeneration of the stomach. Histopathology and differential diagnosis]
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth, Preuschwitzerstr 101, 95445 Bayreuth
    Pathologe 31:171-6. 2010
    ..Gastric ulcers should always be followed-up during the healing phase. A second opinion may confirm the differential diagnosis...
  29. ncbi request reprint Adenoma with gastric differentiation (so-called pyloric gland adenoma) in a heterotopic gastric corpus mucosa in the rectum
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzer Strasse 101, 95445 Bayreuth, Germany
    Virchows Arch 446:542-5. 2005
    ..The present case report is the first case of a pyloric gland-type adenoma within a gastric corpus heterotopia of the rectal mucosa...
  30. doi request reprint Benign serrated colorectal fibroblastic polyps/intramucosal perineuriomas are true mixed epithelial-stromal polyps (hybrid hyperplastic polyp/mucosal perineurioma) with frequent BRAF mutations
    Abbas Agaimy
    Institute of Pathology, University Hospital, Erlangen Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Am J Surg Pathol 34:1663-71. 2010
    ..The perineurial stromal component might be derived from modified pericryptic fibroblasts as a consequence of a yet poorly understood epithelial-stromal interaction...
  31. ncbi request reprint Can the diagnosis of NSAID-induced or Hp-associated gastric ulceration be predicted from histology?
    M Vieth
    Institute of Pathology, Otto von Guericke University Magdeburg, Germany
    Z Gastroenterol 40:783-8. 2002
    ..In conclusion the underlying aetiopathogenesis of gastric ulcerations (NASID/ASA vs. Hp) can be uncovered in a large proportion of patients based on histological examination...
  32. ncbi request reprint INK4a-ARF alterations in Barrett's epithelium, intraepithelial neoplasia and Barrett's adenocarcinoma
    Michael Vieth
    Institute of Pathology, Otto von Guericke University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Virchows Arch 445:135-41. 2004
    ..To study the contribution of each pathway to the carcinogenesis of Barrett's adenocarcinoma, we analysed the alterations of p14ARF and p16INK4a in preneoplastic and neoplastic lesions of this disease...
  33. ncbi request reprint Elevated risk for gastric adenocarcinoma can be predicted from histomorphology
    Michael Vieth
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzer Str 101, 95445 Bayreuth, Germany
    World J Gastroenterol 12:6109-14. 2006
    ..Large prospective long term studies are necessary to prove this and identify new reliable markers for gastric cancer development...
  34. ncbi request reprint [Barrett metaplasia: how dangerous is it really?]
    M Stolte
    Institut fur Pathologie, Klinikum Bayreuth
    Z Gastroenterol 40:5-8. 2002
  35. ncbi request reprint Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics
    Tilman T Rau
    Institute of Pathology, Friedrich Alexander Universitat Erlangen Nurnberg, Krankenhausstraße 8 10, 91054, Erlangen, Germany
    Virchows Arch 464:663-72. 2014
    ..001). Therefore, single well-defined morphological criteria are predictive for genetic alterations in colorectal polyps...
  36. ncbi request reprint Reliable detection of macrolide-resistant Helicobacter pylori via fluorescence in situ hybridization in formalin-fixed tissue
    Stefan Jüttner
    Institute for Pathology, Klinikum Bayreuth, Bayreuth, Germany
    Mod Pathol 17:684-9. 2004
    ..pylori in formalin-fixed, paraffin-embedded biopsy specimens, which represents the routine method of processing tissue obtained upon gastroscopy...
  37. ncbi request reprint Strictures, diaphragms, erosions or ulcerations of ischemic type in the colon should always prompt consideration of nonsteroidal anti-inflammatory drug-induced lesions
    Manfred Stolte
    Institute of Pathology, Klinikum Bayreuth GmbH, Preuschwitzer Str 101, Bayreuth 95445, Germany
    World J Gastroenterol 11:5828-33. 2005
    ..To investigate whether NSAIDs/ASA lesions in the colon can histologically be diagnosed on the basis of ischemic necrosis similar to biopsy-based diagnosis of NSAIDs/ASA-induced erosions and ulcers of the stomach...
  38. ncbi request reprint Radial distribution of dilated intercellular spaces of the esophageal squamous epithelium in patients with reflux disease exhibiting discrete endoscopic lesions
    M Vieth
    Institute of Pathology, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Dig Dis 22:208-12. 2004
    ..We have assessed dilatation of intercellular spaces with regard to: (1) interobserver variability, and (2) whether the incidence of this varies between 'red streaks' and the adjacent normal looking squamous epithelium...
  39. ncbi request reprint Barrett's mucosa, Barrett's dysplasia and Barrett's carcinoma: diagnostic endoscopy without biopsy-taking does not suffice
    M Vieth
    Institute of Pathology, Klinikum Bayreuth, Germany
    Dis Esophagus 13:23-7. 2000
    ....
  40. doi request reprint What is the role of endoscopy and oesophageal biopsies in the management of GERD?
    Jens Krugmann
    Institute of Pathology, Klinikum Bayreuth, Preuschwitzerstr 101, 95445 Bayreuth, Germany
    Best Pract Res Clin Gastroenterol 27:373-85. 2013
    ....
  41. pmc Sporadic adenoma in ulcerative colitis: endoscopic resection is an adequate treatment
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth GmbH, Germany
    Gut 55:1151-5. 2006
    ..In a larger study cohort with more prolonged follow up, we assessed the reliability of this finding...
  42. ncbi request reprint Histological analysis of endoscopic resection specimens from 326 patients with Barrett's esophagus and early neoplasia
    M Vieth
    Institute of Pathology, Otto von Guericke University, Magdeburg, Germany
    Endoscopy 36:776-81. 2004
    ..In the present study we analyzed the histological characteristics of endoscopic resection specimens of Barrett's neoplasia...
  43. ncbi request reprint Pyloric gland adenoma: a clinico-pathological analysis of 90 cases
    M Vieth
    Institute of Pathology, University of Magdeburg, Germany
    Virchows Arch 442:317-21. 2003
    ..Apart from case reports, few clinical data are available on these patients. We therefore conducted a search of the archived material collected between 1990 and 2000 for more clinical data on patients with this rare lesion...
  44. ncbi request reprint Gastritis and gastric cancer: which morphological type of Helicobacter gastritis is a precancerous risk?
    M Stolte
    Institut fur Pathologie, Klinikum Bayreuth, Bayern, Germany
    Chin J Dig Dis 6:110-1. 2005
  45. doi request reprint ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapancreatic origin
    Abbas Agaimy
    Institute of Pathology, University Hospital, Erlangen, Germany
    Mod Pathol 26:995-1003. 2013
    ..These findings modify the role of ISL1 as a marker for pancreatic neuroendocrine neoplasms and suggest that ISL1 has a broader involvement in differentiation and growth of neuroendocrine neoplasms than has so far been assumed. ..
  46. ncbi request reprint Mutations of BRAF and KRAS2 in the development of Barrett's adenocarcinoma
    Florian Sommerer
    Institute of Pathology, University of Leipzig, Liebigstrasse 26, Leipzig 04103, Germany
    Oncogene 23:554-8. 2004
    ..We conclude that the disruption of the Raf/MEK/ERK (MAPK) kinase pathway is a frequent but also early event in the development of Barrett's adenocarcinoma...
  47. ncbi request reprint [Are dilated intercellular spaces an invariable histological sign for gastro-oesophageal reflux disease?]
    M Vieth
    Institut fur Pathologie, Klinikum Bayreuth
    Z Gastroenterol 44:341-3. 2006
  48. pmc Methylation of SOCS-3 and SOCS-1 in the carcinogenesis of Barrett's adenocarcinoma
    I Tischoff
    Institute of Pathology, University of Bochum, Burkle de la Camp Platz 1, D 44789 Bochum, Germany
    Gut 56:1047-53. 2007
    ..The suppressors of cytokine signalling (SOCS) are inhibitors of cytokine signalling; methylation of SOCS-3 has been implicated in the tumorigenesis of liver as well as head and neck cancer...
  49. ncbi request reprint Juvenile-like (inflammatory/hyperplastic) mucosal polyps of the gastrointestinal tract in neurofibromatosis type 1
    Abbas Agaimy
    Institute of Pathology, University Hospital, Erlangen, Germany
    Histopathology 64:777-86. 2014
    ..Inflammatory (juvenile-like) polyps have not been recognised to date as specific gastrointestinal (GI) manifestations of NF-1...
  50. ncbi request reprint Risk factors for symptom relapse in collagenous colitis after withdrawal of short-term budesonide therapy
    Stephan Miehlke
    Center for Digestive Diseases, Hamburg, Germany Department of Gastroenterology, Aalborg Hospital, Aalborg, Denmark Medical Department I, Siloah Hospital, Hannover, Germany Medical Department III, University Hospital, Dresden, Germany Institute for Medical Informatics and Biometry, Technical University, Dresden, Germany Lanserhof Hamburg GmbH, Hamburg, Germany Institute of Pathology, Aalborg Hospital, Aalborg, Denmark Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany Institute of Pathology, University Hospital, Dresden, Germany and Diagnostic Center, Section of Gastroenterology, Regional Hospital Silkeborg, Silkeborg, Denmark
    Inflamm Bowel Dis 19:2763-7. 2013
    ..The aim of this study was to identify the risk factors for symptom relapse in patients with collagenous colitis after withdrawal of short-term budesonide therapy...
  51. doi request reprint Virtual chromoendoscopy for prediction of severity and disease extent in patients with inflammatory bowel disease: a randomized controlled study
    Helmut Neumann
    Department of Medicine I, University of Erlangen Nuremberg, Germany
    Inflamm Bowel Dis 19:1935-42. 2013
    ..Aim was to determine whether computed virtual chromoendoscopy has the potential to enhance assessment of disease severity and extent in patients with mild or inactive IBD in comparison to high-definition white-light endoscopy...
  52. doi request reprint Endocytoscopy allows accurate in vivo differentiation of mucosal inflammatory cells in IBD: a pilot study
    Helmut Neumann
    Department of Medicine I, University of Erlangen Nuremberg, Germany
    Inflamm Bowel Dis 19:356-62. 2013
    ..The aim of our study was to determine the reliability of EC for the discrimination of mucosal inflammatory cells and intestinal inflammatory disease activity in patients with IBD...
  53. doi request reprint Mucinous differentiation in colorectal cancer--indicator of poor prognosis?
    Cord Langner
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, Graz, Austria
    Histopathology 60:1060-72. 2012
    ..To analyse the prognostic impact of mucinous differentiation in colorectal mucinous adenocarcinomas and adenocarcinomas with a mucinous component...
  54. ncbi request reprint [Risk factors for lymphatic metastasis from pT1 colorectal adenocarcinoma]
    P Deinlein
    Institut fur Pathologie, Klinikum Bayreuth, Bayreuth, Germany
    Pathologe 24:387-93. 2003
    ..Drawing on the literature and an analysis of our own patients, we demonstrate a positive correlation between these new markers and an elevated risk of the presence of lymph node metastasis...
  55. ncbi request reprint Analysis of symptoms and endoscopic findings in 117 patients with histological diagnoses of eosinophilic esophagitis
    S Muller
    Institute of Pathology, Munich University, Munich, Germany
    Endoscopy 39:339-44. 2007
    ..In this study, symptoms, accompanying allergic disorders, and endoscopic findings in 117 patients with eosinophilic esophagitis were analyzed retrospectively...
  56. ncbi request reprint Gastroesophageal reflux disease leads to major alterations in lectin-binding in the columnar epithelium of the gastroesophageal junction
    Helmut Neumann
    Otto von Guericke University Magdeburg, Department of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg, Germany
    Scand J Gastroenterol 42:791-8. 2007
    ..The aim was to investigate the binding patterns of lectins UEA-I, DBA, HPA and PNA at the squamocolumnar junction in relation to the existence of gastroesophageal reflux disease (GERD) and Helicobacter pylori (H. pylori) infection...
  57. ncbi request reprint Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis
    Ralf Kiesslich
    I Medical Clinic, Johannes Gutenberg University of Mainz, Germany
    Gastroenterology 132:874-82. 2007
    ..In this study we assessed the value of combined chromoscopy and endomicroscopy for the diagnosis of intraepithelial neoplasias in a randomized controlled trial...
  58. ncbi request reprint Curative endoscopic resection of early esophageal adenocarcinomas (Barrett's cancer)
    Christian Ell
    Department of Internal Medicine II, HSK Wiesbaden, Teaching Hospital of the University of Mainz, Wiesbaden, Germany
    Gastrointest Endosc 65:3-10. 2007
    ....
  59. ncbi request reprint Cytokeratin 7/20 and mucin core protein expression in ulcerative colitis-associated colorectal neoplasms
    Natsuko Tatsumi
    Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kamigyo ku, 602 8566 Kyoto, Japan
    Virchows Arch 448:756-62. 2006
    ..These results suggest that gastric-type mucins play an important role in the initial step of CC-tumorigenesis, and CK7 and gastric-type mucins may be useful in the differential diagnosis between UC-associated neoplasms and sporadic ones...
  60. ncbi request reprint Confocal laser endomicroscopy for in vivo diagnosis of early squamous cell carcinoma in the esophagus
    Oliver Pech
    Department of Medicine II, HSK Wiesbaden, Teaching Hospital of the University of Mainz, Germany
    Clin Gastroenterol Hepatol 6:89-94. 2008
    ..This study was designed to assess the potential of endomicroscopy for predicting histology in vivo during routine endoscopy in patients with early squamous cell cancer...
  61. doi request reprint Nighttime heartburn in patients with gastroesophageal reflux disease under routine care
    Marc Nocon
    Institute for Social Medicine, Epidemiology, and Health Economics, Charite University Medical Center, Berlin, Germany
    Digestion 77:69-72. 2008
    ..Gastroesophageal reflux disease (GERD) is a common disorder. The aim of our study was to describe the prevalence of nighttime heartburn and its associations with esophagitis, Barrett's esophagus, and extra-esophageal symptoms...
  62. ncbi request reprint High-grade dysplasia in sporadic fundic gland polyps: clinically relevant or not?
    Manfred Stolte
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Eur J Gastroenterol Hepatol 15:1153-6. 2003
    ..According to the data available at present, such a constellation must be regarded as an extremely rare event...
  63. doi request reprint Early Barrett's carcinoma with "low-risk" submucosal invasion: long-term results of endoscopic resection with a curative intent
    Hendrik Manner
    Department of Internal Medicine II, HSK Wiesbaden, Wiesbaden, Germany
    Am J Gastroenterol 103:2589-97. 2008
    ..In consequence, also these patients might be eligible for curative ET. The aim of this study was to prospectively evaluate the efficacy and safety of endoscopic resection (ER) in these patients...
  64. ncbi request reprint Barrett's esophagus and neoplasia: data from the Bayreuth Barrett's archive
    Michael Vieth
    Gastroenterology 122:590-1. 2002
  65. ncbi request reprint Local endoscopic therapy for intraepithelial high-grade neoplasia and early adenocarcinoma in Barrett's oesophagus: acute-phase and intermediate results of a new treatment approach
    Andrea May
    Department of Internal Medicine II, Dr Horst Schmidt Kliniken, Ludwig Erhard Strasse 100, 65199 Wiesbaden, Germany
    Eur J Gastroenterol Hepatol 14:1085-91. 2002
    ..Radical oesophageal resection has until now been regarded as the gold standard for treatment in intraepithelial high-grade neoplasia or early adenocarcinoma of the oesophagus. However, the mortality and morbidity rates are substantial...
  66. ncbi request reprint Gastric-type adenocarcinoma of the duodenal second portion histogenetically associated with hyperplasia and gastric-foveolar metaplasia of Brunner's glands
    Ryoji Kushima
    Department of Clinical Laboratory Medicine, Shiga University of Medical Science, Seta, Otsu, Shiga 520 2192 Japan
    Virchows Arch 440:655-9. 2002
    ..Therefore the present carcinoma is thought to have developed under induction of gastric-foveolar differentiation in a manner very similar to that of gastric metaplasia in hyperplastic Brunner's glands...
  67. ncbi request reprint Cholesterol glucosylation promotes immune evasion by Helicobacter pylori
    Christian Wunder
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Chariteplatz 1, 10117 Berlin, Germany
    Nat Med 12:1030-8. 2006
    ..Thus, we propose a mechanism regulating the host-pathogen interaction whereby glucosylation of a lipid tips the scales towards immune evasion or response...
  68. ncbi request reprint Long-term results of photodynamic therapy with 5-aminolevulinic acid for superficial Barrett's cancer and high-grade intraepithelial neoplasia
    Oliver Pech
    Department of Medicine II, HSK Wiesbaden, Teaching Hospital of the University of Mainz, Germay
    Gastrointest Endosc 62:24-30. 2005
    ..However, long-term results in patients with high-grade intraepithelial neoplasia (HGIN) or with early cancer are still lacking...
  69. ncbi request reprint Prospective follow-up data from the ProGERD study suggest that GERD is not a categorial disease
    Joachim Labenz
    Faculty of Medicine, University of Duisburg Essen, Ev Jung Stilling Hospital, Siegen, Germany
    Am J Gastroenterol 101:2457-62. 2006
    ..Aim of the study was to assess progression or regression of GERD over 2 yr in a large cohort of patients (N = 3,894) under routine clinical care in Germany, Austria, and Switzerland (ProGERD study)...
  70. ncbi request reprint Confocal laser endomicroscopy
    Ralf Kiesslich
    1st Medical Clinic, Johannes Gutenberg University Mainz, Mainz, Germany
    Gastrointest Endosc Clin N Am 15:715-31. 2005
    ..This review describes the optical and diagnostic possibilities of confocal laser endomicroscopy...
  71. ncbi request reprint Helicobacter pylori induces gastritis and intestinal metaplasia but no gastric adenocarcinoma in Mongolian gerbils
    Anders Elfvin
    Department of Gastrosurgical Research, Sahlgrenska Academy, Goteborg University, Sahlgrensky University Hospital Box 75038, SE 400 36 Gothenburg, Sweden
    Scand J Gastroenterol 40:1313-20. 2005
    ..The purpose of this study was to compare two different H. pylori strains and elucidate whether adenocarcinomas developed in gerbils...
  72. ncbi request reprint Cathepsins K, L, B, X and W are differentially expressed in normal and chronically inflamed gastric mucosa
    Frank Buhling
    Institute of Immunology, Otto von Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    Biol Chem 385:439-45. 2004
    ..Immunohistochemistry revealed specific expression of cathepsin X (macrophages), cathepsin K (parietal cells) and cathepsin W (lymphocytes), whereas cathepsins B and L were predominantly expressed in epithelial cells...
  73. ncbi request reprint Helicobacter pylori infection, but not low-dose aspirin, results in a local reduction of the secretory leukocyte protease inhibitor in gastroduodenal mucosa
    Thomas Wex
    Department of Gastroenterology, Hepatology and Infectious Diseases, Tongji Medical College of Basic Medical Sciences, Huazhong University of Wuhan, China
    Helicobacter 11:31-8. 2006
    ..Therefore, the effect of low-dose aspirin on gastrointestinal SLPI expression was analyzed in the context of H. pylori infection...
  74. ncbi request reprint Secretory leukocyte protease inhibitor expression in various types of gastritis: a specific role of Helicobacter pylori infection
    Istvan Hritz
    Department of Gastroenterology, Hepatology and Infectious Diseases, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Gastroenterol Hepatol 18:277-82. 2006
    ..The aim of the study was to investigate whether SLPI downregulation of gastric mucosa represents a specific phenomenon of H. pylori infection or is generally linked to gastric inflammation...
  75. ncbi request reprint TFF3 expression at the esophagogastric junction is increased in gastro-esophageal reflux disease (GERD)
    Ulrich Peitz
    Department of Gastroenterology, Hepatology, and Infectiology, Otto von Guericke University, Leipziger Str 44, D 39120 Magdeburg, Germany
    Peptides 25:771-7. 2004
    ..pylori status or to tumor necrosis factor-alpha (TNF-alpha) expression. The expression of TFF3 at the cardia may represent an adaptation to GERD and precede the development of Barrett's esophagus...
  76. ncbi request reprint A negative Helicobacter pylori serology test is more reliable for exclusion of premalignant gastric conditions than a negative test for current H. pylori infection: a report on histology and H. pylori detection in the general adult population
    Tom Storskrubb
    Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden
    Scand J Gastroenterol 40:302-11. 2005
    ..pylori infection and associated gastric mucosal findings by means of histological survey of a random adult population...
  77. ncbi request reprint Cardia-type metaplasia arising in the remnant esophagus after cardia resection
    Ulrich Peitz
    Department of Gastroenterology, Hepatology and Infectiology, Otto von Guericke University, Magdeburg, Germany
    Gastrointest Endosc 59:810-7. 2004
    ..The aim of this study was to investigate the mucosal effects of esophagogastrostomy, an artificial interface between esophageal squamous and gastric oxyntic epithelium...
  78. ncbi request reprint In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopy
    Ralf Kiesslich
    Medical Clinic, Johannes Gutenberg University Mainz, Germany
    Clin Gastroenterol Hepatol 4:979-87. 2006
    ..Here, we have applied this technique to the in vivo diagnosis of Barrett's epithelium and associated neoplasia...
  79. ncbi request reprint Ciliated surface in the esophagogastric junction zone: a precursor of Barrett's mucosa or ciliated pseudostratified metaplasia?
    Kaiyo Takubo
    Human Tissue Research Group, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
    Am J Surg Pathol 29:211-7. 2005
    ..These findings may suggest that squamous metaplasia-like change at the EGJ is not a precursor of Barrett's mucosa but rather is a form of pseudostratified metaplasia...
  80. ncbi request reprint Long-term follow-up after complete ablation of Barrett's esophagus with argon plasma coagulation
    Ahmed Madisch
    Medical Department I, Technical University Hospital, Fetscherstr 74, D 01307 Dresden, Germany
    World J Gastroenterol 11:1182-6. 2005
    ..To report the long-term outcome of patients after complete ablation of non-neoplastic Barrett's esophagus (BE) with respect to BE relapse and development of intraepithelial neoplasia or esophageal adenocarcinoma...
  81. ncbi request reprint Islands of squamous epithelium and their surrounding mucosa in columnar-lined esophagus: a pathognomonic feature of Barrett's esophagus?
    Kaiyo Takubo
    Human Tissue Research Group, Tokyo Metropolitan Institute of Gerontology, Japan
    Hum Pathol 36:269-74. 2005
    ..From a practical point of view, biopsy specimens from columnar-lined mucosa of the esophagus do not always show intestinal metaplasia (specialized intestinal metaplasia)...
  82. pmc Hypermethylation and loss of expression of glutathione peroxidase-3 in Barrett's tumorigenesis
    Ok Jae Lee
    Digestive Health Center of Excellence, University of Virginia Health System, Charlottesville, VA 22908 0708, USA
    Neoplasia 7:854-61. 2005
    ....
  83. ncbi request reprint Prevalence of H pylori associated "high risk gastritis" for development of gastric cancer in patients with normal endoscopic findings
    Andreas Leodolter
    Department of Gastroenterology and Hepatology, Otto von Guericke University, Leipziger Street 44, Magdeburg D 39120, Germany
    World J Gastroenterol 12:5509-12. 2006
    ..To investigate the prevalence of H pylori associated corpus-predominant gastritis (CPG) or pangastritis, severe atrophy, and intestinal metaplasia (IM) in patients without any significant abnormal findings during upper-GI endoscopy...
  84. ncbi request reprint Pyloric gland adenoma arising in Barrett's esophagus with mucin immunohistochemical and molecular cytogenetic evaluation
    Ryoji Kushima
    Division of Diagnostic Pathology, Shiga University of Medical Science, Seta, Otsu, 520 2192 Shiga, Japan
    Virchows Arch 446:537-41. 2005
    ..2, 2q14.1-ter, 5q31.3-32, 6q23-24, 8q23-24.2, 11q22.3-24 and 18q21.1-22. This is the first case of pyloric gland adenoma found to arise in Barrett's epithelium of the esophagus, showing its unstable and precancerous nature...
  85. ncbi request reprint Gastric-type well-differentiated adenocarcinoma and pyloric gland adenoma of the stomach
    Ryoji Kushima
    Division of Diagnostic Pathology, Shiga University of Medical Science Hospital, Otsu, 520 2192, Japan
    Gastric Cancer 9:177-84. 2006
    ..In this article, we review and discuss the clinicopathological and molecular pathological aspects of gastric-type well-differentiated adenocarcinomas and pyloric gland adenomas, mainly based on our published and unpublished data...
  86. ncbi request reprint Acid challenge to the human esophageal mucosa: effects on epithelial architecture in health and disease
    Mogens Bove
    Department of Otolaryngology, Sahlgrenska University Hospital, Goteborg, Sweden
    Dig Dis Sci 50:1488-96. 2005
    ..A protective effect of luminal nitric oxide on DIS development is suggested...
  87. ncbi request reprint Expression of G1 phase cyclins in human gastric cancer and gastric mucosa of first-degree relatives
    Stephan Miehlke
    Medical Department I, Gastroenterology, Hematology and Oncology, Technical University Hospital, Dresden, Germany
    Dig Dis Sci 47:1248-56. 2002
    ..Our data suggest that deregulation of G1 phase cyclins may play a role in gastric carcinogenesis, and may point to the presence of molecular alterations in individuals at an increased risk for gastric cancer...
  88. ncbi request reprint Acid challenge to the esophageal mucosa: effects on local nitric oxide formation and its relation to epithelial functions
    Mogens Bove
    Department of Otolaryngology, NAL, Trollhattan, Sweden
    Dig Dis Sci 50:640-8. 2005
    ..Blood flow was lower among reflux patients but did not correlate with acid exposure or nitric oxide. Nitric oxide is formed following acid perfusion and predominantly in gastroesophageal reflux disease...
  89. ncbi request reprint A prospective randomized trial of two different endoscopic resection techniques for early stage cancer of the esophagus
    Andrea May
    HSK Wiesbaden, Nuremberg, Germany
    Gastrointest Endosc 58:167-75. 2003
    ..However, there is no report of a prospective randomized comparison of different techniques...
  90. ncbi request reprint DAPK promotor methylation is an early event in colorectal carcinogenesis
    Falk Mittag
    Department of Pathology, Otto von Guericke University Magdeburg, Germany
    Cancer Lett 240:69-75. 2006
    ..We suggest that DAPK promotor hypermethylation may play an important role in the early steps of tumor progression in colorectal carcinoma...
  91. ncbi request reprint No prognostic impact of isolated lymphovascular invasion after radical resection of rectal cancer--results of a multicenter observational study
    Henry Ptok
    Department of General, Abdominal and Vascular Surgery, University Hospital, Magdeburg, Germany
    Int J Colorectal Dis 22:749-56. 2007
    ..The prognostic impact of isolated lymphovascular invasion (LVI) after radical resection of rectal cancer is controversially discussed. However, it could be relevant to decide for an adjuvant treatment...
  92. pmc Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: the population-based Kalixanda study
    Jukka Ronkainen
    Department of Neurobiology, Care Sciences and Society, Centre for Family and Community Medicine, Karolinska Institutet, Stockholm, Sweden
    Gut 56:615-20. 2007
    ..Eosinophilic oesophagitis may be increasing but the prevalence in the general population remains unknown. Our aim was to assess this and the presence of eosinophils in the distal oesophageal epithelium in the community...
  93. ncbi request reprint The optimal dose of 5-aminosalicylic acid in active ulcerative colitis: a dose-finding study with newly developed mesalamine
    Wolfgang Kruis
    Evangelisches Krankenhaus Kalk, University of Cologne, Cologne, Germany
    Clin Gastroenterol Hepatol 1:36-43. 2003
    ..A new pellet preparation was designed combining slow and delayed release properties. Aims of the study were to find the optimal dose and to test efficacy and safety of a new 5-aminosalicylic acid formulation...
  94. ncbi request reprint Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis
    Irina Kouznetsova
    Institut für Molekularbiologie und Medizinische Chemie, Universitatsklinikum, Otto von Guericke Universitat Magdeburg, Leipziger Strasse 44, Magdeburg, Germany
    Cell Tissue Res 328:365-74. 2007
    ..This indicates the special requirement, particularly of the esophagogastric junction, for TFF3-triggered protection and repair...
  95. ncbi request reprint Vascular endothelial growth factor-D and its receptor VEGFR-3: two novel independent prognostic markers in gastric adenocarcinoma
    Stefan Jüttner
    Laboratory for Angiogenesis and Tumor Metastasis, Charite, Campus Virchow Klinikum, Berlin, Germany
    J Clin Oncol 24:228-40. 2006
    ..Therefore, we analyzed expression and prognostic significance of VEGF-D along with VEGF-C, and VEGFR-3 in gastric adenocarcinomas...
  96. ncbi request reprint A gradient of TFF3 (trefoil factor family 3) peptide synthesis within the normal human gastric mucosa
    Irina Kouznetsova
    Institut für Molekularbiologie und Medizinische Chemie, Universitatsklinikum, Otto von Guericke Universitat, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Cell Tissue Res 316:155-65. 2004
    ..TFF3 might therefore have important physiological functions in the stomach, e.g. as a luminal surveillance peptide maintaining particularly the integrity of the antral and pyloric mucosa...
  97. ncbi request reprint Endoscopic resection of superficial esophageal squamous-cell carcinomas: Western experience
    Oliver Pech
    Department of Medicine II, HSK Wiesbaden, Teaching Hospital of the University of Mainz, Germany
    Am J Gastroenterol 99:1226-32. 2004
    ..In the present observational study, we report on the largest prospective series so far in Western countries of patients with early squamous-cell cancer or carcinoma in situ, who were treated using endoscopic resection therapy...
  98. ncbi request reprint Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease
    Eike Hollenbach
    Institute of Experimental Internal Medicine, Otto von Guericke University, Magdeburg, Germany
    FASEB J 18:1550-2. 2004
    ..Thus, RICK could represent a novel target for future therapies in human IBD...
  99. ncbi request reprint A prospective, randomized study of quadruple therapy and high-dose dual therapy for treatment of Helicobacter pylori resistant to both metronidazole and clarithromycin
    Stephan Miehlke
    Medical Department I, Technical University Hospital, Dresden, Germany
    Helicobacter 8:310-9. 2003
    ..Here, we investigated the efficacy of high-dose dual therapy and quadruple therapy as salvage treatments for eradication of H. pylori resistant to both metronidazole and clarithromycin...
  100. ncbi request reprint Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo
    Ralf Kiesslich
    First Medical Clinic, Johannes Gutenberg University of Mainz, Mainz, Germany
    Gastroenterology 127:706-13. 2004
    ..The aim of the present study was to assess its potential for prediction of histology during screening colonoscopy for colorectal cancer...
  101. ncbi request reprint Technology insight: confocal laser endoscopy for in vivo diagnosis of colorectal cancer
    Ralf Kiesslich
    I Med Klinik und Poliklinik, Johannes Gutenberg Universitat Mainz, Mainz, Germany
    Nat Clin Pract Oncol 4:480-90. 2007
    ..Taken together, CLE has led colorectal cancer endoscopy into a new era. CLE can no longer be regarded as just another endoscopic technique, but emerges as a crucial novel imaging technique for in vivo diagnosis of colorectal cancer...