Birgit C Viertlboeck

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Characterization of the chicken C-type lectin-like receptors B-NK and B-lec suggests that the NK complex and the MHC share a common ancestral region
    Sally L Rogers
    Institute for Animal Health, Compton, Berkshire, United Kingdom
    J Immunol 174:3475-83. 2005
  2. doi request reprint Chicken immunoregulatory Ig-like receptor families: an overview and expression details on ggTREM-A1
    Birgit C Viertlboeck
    Institute for Animal Physiology, Department of Veterinary Sciences, Ludwig Maximilians University, Munich, Germany
    Dev Comp Immunol 41:403-12. 2013
  3. doi request reprint Complexity of expressed CHIR genes
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Veterinaerstr 13, 80539 Munich, Germany
    Dev Comp Immunol 34:866-73. 2010
  4. ncbi request reprint A novel activating chicken IgY FcR is related to leukocyte receptor complex (LRC) genes but is located on a chromosomal region distinct from the LRC and FcR gene clusters
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 182:1533-40. 2009
  5. ncbi request reprint Characterization of the chicken CD200 receptor family
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, 80539 Munich, Germany
    Mol Immunol 45:2097-105. 2008
  6. doi request reprint The chicken leukocyte receptor complex encodes a family of different affinity FcY receptors
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 182:6985-92. 2009
  7. ncbi request reprint The chicken immunoregulatory receptor families SIRP, TREM, and CMRF35/CD300L
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Veterinarstr 13, Munich 80539, Germany
    Immunogenetics 58:180-90. 2006
  8. doi request reprint Chicken IgY binds its receptor at the CH3/CH4 interface similarly as the human IgA: Fc alpha RI interaction
    Jana Pürzel
    Department of Veterinary Sciences, University of Munich, Munich, Germany
    J Immunol 183:4554-9. 2009
  9. doi request reprint Chicken NK cell receptors
    Christian Straub
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Germany
    Dev Comp Immunol 41:324-33. 2013
  10. ncbi request reprint The chicken leukocyte receptor complex: a highly diverse multigene family encoding at least six structurally distinct receptor types
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 175:385-93. 2005

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Characterization of the chicken C-type lectin-like receptors B-NK and B-lec suggests that the NK complex and the MHC share a common ancestral region
    Sally L Rogers
    Institute for Animal Health, Compton, Berkshire, United Kingdom
    J Immunol 174:3475-83. 2005
    ..This provides evidence that C-type lectin-like receptors were present in the preduplication, primordial MHC region, and suggests that an original function of MHC molecules was for recognition by NK cell receptors encoded nearby...
  2. doi request reprint Chicken immunoregulatory Ig-like receptor families: an overview and expression details on ggTREM-A1
    Birgit C Viertlboeck
    Institute for Animal Physiology, Department of Veterinary Sciences, Ludwig Maximilians University, Munich, Germany
    Dev Comp Immunol 41:403-12. 2013
    ..In conclusion, ggTREM-A1 is expressed on a variety of cells, relevant for the immune system, possibly combining physiological function of different mammalian TREM...
  3. doi request reprint Complexity of expressed CHIR genes
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Veterinaerstr 13, 80539 Munich, Germany
    Dev Comp Immunol 34:866-73. 2010
    ..This analysis of expressed CHIR genes in different chickens demonstrates an unusual polymorphism of expressed receptors, where only few are conserved between chickens...
  4. ncbi request reprint A novel activating chicken IgY FcR is related to leukocyte receptor complex (LRC) genes but is located on a chromosomal region distinct from the LRC and FcR gene clusters
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 182:1533-40. 2009
    ..Surprisingly, ggFcR is not encoded in the leukocyte receptor complex, but it is located as a single isolated gene at the extremity of chicken chromosome 20...
  5. ncbi request reprint Characterization of the chicken CD200 receptor family
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, 80539 Munich, Germany
    Mol Immunol 45:2097-105. 2008
    ..Furthermore, the presence of potentially soluble CD200R molecules implies an important role for these in the regulation of myeloid cells in chicken...
  6. doi request reprint The chicken leukocyte receptor complex encodes a family of different affinity FcY receptors
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 182:6985-92. 2009
    ..These results imply that multiple FcY receptors of variable affinity are encoded by the CHIR locus and that different chicken lines may express both unique as well as highly conserved FcY receptors...
  7. ncbi request reprint The chicken immunoregulatory receptor families SIRP, TREM, and CMRF35/CD300L
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Veterinarstr 13, Munich 80539, Germany
    Immunogenetics 58:180-90. 2006
    ..In conclusion, the mammalian diversity of immunoregulatory molecules is present the chicken suggesting an important role for TREM, SIRP, and CMRF35/CD300L in a functionally conserved network...
  8. doi request reprint Chicken IgY binds its receptor at the CH3/CH4 interface similarly as the human IgA: Fc alpha RI interaction
    Jana Pürzel
    Department of Veterinary Sciences, University of Munich, Munich, Germany
    J Immunol 183:4554-9. 2009
    ..The identification of the IgY Cv3/Cv4 interdomain region as critical for binding to CHIR-AB1 significantly enhances our understanding of the IgY receptor interaction and allows further conclusions regarding the FcR phylogeny...
  9. doi request reprint Chicken NK cell receptors
    Christian Straub
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Germany
    Dev Comp Immunol 41:324-33. 2013
    ..Here we will review recent progress regarding the diverse NK cell receptor families, with special emphasis on novel families identified in the chicken genome with potential as chicken NK cell receptors...
  10. ncbi request reprint The chicken leukocyte receptor complex: a highly diverse multigene family encoding at least six structurally distinct receptor types
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 175:385-93. 2005
    ..Fluorescence in situ hybridization localized the CHIR gene cluster to microchromosome 31 and identified this region as orthologous to the human leukocyte receptor complex...
  11. pmc The chicken leukocyte receptor complex encodes a primordial, activating, high-affinity IgY Fc receptor
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, 80539 Munich, Germany
    Proc Natl Acad Sci U S A 104:11718-23. 2007
    ..CHIR-AB1 thus represents a primordial Fc receptor that combines features of different mammalian counterparts...
  12. pmc The Turkey Ig-like receptor family: identification, expression and function
    Katharina Windau
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Munich, Germany
    PLoS ONE 8:e59577. 2013
    ..In summary, although the turkey harbors similar LRC genes as the chicken, their distribution seems to be distinct with predominance on thrombocytes rather than lymphocytes...
  13. ncbi request reprint Chicken Ig-like receptor B2, a member of a multigene family, is mainly expressed on B lymphocytes, recruits both Src homology 2 domain containing protein tyrosine phosphatase (SHP)-1 and SHP-2, and inhibits proliferation
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 173:7385-93. 2004
    ..Together, we have identified a multigene family containing multiple CHIR including one receptor designated CHIR-B2 that is mainly expressed on B lymphocytes and inhibits cellular proliferation by recruitment of SHP-1 and SHP-2...
  14. doi request reprint A striking example of convergent evolution observed for the ggFcR:IgY interaction closely resembling that of mammalian FcR:IgG
    Barbara Schreiner
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Veterinarstrasse 13, 80539 Munich, Germany
    Dev Comp Immunol 36:566-71. 2012
    ..These results demonstrate that ggFcR has a contact site to IgY which closely resembles that of human IgG bound to FcR...
  15. doi request reprint The red jungle fowl leukocyte receptor complex contains a large, highly diverse number of chicken immunoglobulin-like receptor (CHIR) genes
    Katharina M Lochner
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Veterinarstr 13, 80539 Munich, Germany
    Mol Immunol 47:1956-62. 2010
    ....
  16. doi request reprint The chicken leukocyte receptor cluster
    Birgit C Viertlboeck
    Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munchen, Veterinarstr 13, 80539 Munchen, Germany
    Vet Immunol Immunopathol 144:1-10. 2011
    ..Detailed analyses of CHIR-AB1, its crystal structure, the interaction to IgY and functional capabilities allow us to draw conclusions regarding Fc receptor phylogeny and function...
  17. ncbi request reprint Chicken C-type lectin-like receptor B-NK, expressed on NK and T cell subsets, binds to a ligand on activated splenocytes
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Veterinarstr 13, 80539 Munich, Germany
    Mol Immunol 45:1398-404. 2008
    ..In summary, B-NK is expressed by NK cells and T cell subsets, and it binds to a ligand on activated cells...
  18. doi request reprint The chicken SLAM family
    Christian Straub
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Veterinarstr 13, 80539 Munich, Germany
    Immunogenetics 65:63-73. 2013
    ..The characterization of the chicken SLAM family of receptors and the SAP adaptors demonstrates the phylogenetic conservation of this family, in particular, its signaling capacities...
  19. doi request reprint Chicken SLAMF4 (CD244, 2B4), a receptor expressed on thrombocytes, monocytes, NK cells, and subsets of αβ-, γδ- T cells and B cells binds to SLAMF2
    Christian Straub
    Institute for Animal Physiology, Department of Veterinary Sciences, University of Munich, Veterinarstr 13, 80539 Munich, Germany
    Dev Comp Immunol 42:159-68. 2014
    ..In conclusion, the avian SLAMF4 expression markedly differs from mammals; it binds to SLAMF2 and will be an important tool to discriminate several γδ T cell subsets...
  20. pmc The crystal structure of CHIR-AB1: a primordial avian classical Fc receptor
    Tal I Arnon
    Division of Biology, 114 96 and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA
    J Mol Biol 381:1012-24. 2008
    ..Taken together, these results add to the structural understanding of Fc receptors and their functional mechanisms...