Ludger Tebartz van Elst

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. pmc Retinal contrast transfer functions in adults with and without ADHD
    Emanuel Bubl
    Department of Psychiatry and Psychotherapy, Albert Ludwigs University of Freiburg, Freiburg, Germany
    PLoS ONE 8:e61728. 2013
  2. ncbi request reprint High-functioning autism spectrum disorder as a basic disorder in adult psychiatry and psychotherapy: psychopathological presentation, clinical relevance and therapeutic concepts
    Ludger Tebartz van Elst
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstraße 5, 79104, Freiburg, Germany
    Eur Arch Psychiatry Clin Neurosci 263:S189-96. 2013
  3. pmc Amygdala size in amyotrophic lateral sclerosis without dementia: an in vivo study using MRI volumetry
    Elmar H Pinkhardt
    Department of Neurology, University of Ulm, Ulm, Germany
    BMC Neurol 6:48. 2006
  4. doi request reprint Amygdala volume loss in patients with dysphoric disorder of epilepsy
    Ludger Tebartz van Elst
    Section for Experimental NeuroPsychiatry, Albert Ludwigs University, Freiburg, Germany
    Epilepsy Behav 16:105-12. 2009
  5. doi request reprint Local area network inhibition: a model of a potentially important paraepileptic pathomechanism in neuropsychiatric disorders
    Ludger Tebartz van Elst
    Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    Epilepsy Behav 22:231-9. 2011
  6. ncbi request reprint Evidence of disturbed amygdalar energy metabolism in patients with borderline personality disorder
    L Tebartz van Elst
    South German Brain Imaging Center, and Department of Psychiatry and Psychotherapy, Medical School, Albert Ludwigs University Freiburg, Hauptstrasse 5, 79104 Freiburg, Germany
    Neurosci Lett 417:36-41. 2007
  7. doi request reprint The psychosocial impact of epilepsy in older people
    Ludger Tebartz van Elst
    Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstr 5, 79104 Freiburg, Germany
    Epilepsy Behav 15:S17-9. 2009
  8. pmc Chronic insomnia and MRI-measured hippocampal volumes: a pilot study
    Dieter Riemann
    Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstr 5, D 79104 Germany
    Sleep 30:955-8. 2007
  9. doi request reprint Reduced interhemispheric structural connectivity between anterior cingulate cortices in borderline personality disorder
    NICOLAS RUSCH
    Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    Psychiatry Res 181:151-4. 2010
  10. doi request reprint Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder
    NICOLAS RUSCH
    Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
    World J Biol Psychiatry 11:372-81. 2010

Collaborators

Detail Information

Publications48

  1. pmc Retinal contrast transfer functions in adults with and without ADHD
    Emanuel Bubl
    Department of Psychiatry and Psychotherapy, Albert Ludwigs University of Freiburg, Freiburg, Germany
    PLoS ONE 8:e61728. 2013
    ..As the contrast gain in an earlier study clearly separated the patients with depression from the controls, we assume that retinal contrast gain might be a specific marker in depression...
  2. ncbi request reprint High-functioning autism spectrum disorder as a basic disorder in adult psychiatry and psychotherapy: psychopathological presentation, clinical relevance and therapeutic concepts
    Ludger Tebartz van Elst
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstraße 5, 79104, Freiburg, Germany
    Eur Arch Psychiatry Clin Neurosci 263:S189-96. 2013
    ..To conclude, we outline first treatment concepts in out- and in-patient settings. ..
  3. pmc Amygdala size in amyotrophic lateral sclerosis without dementia: an in vivo study using MRI volumetry
    Elmar H Pinkhardt
    Department of Neurology, University of Ulm, Ulm, Germany
    BMC Neurol 6:48. 2006
    ..The aim of this study was to investigate possible alterations of amygdala volumes in vivo...
  4. doi request reprint Amygdala volume loss in patients with dysphoric disorder of epilepsy
    Ludger Tebartz van Elst
    Section for Experimental NeuroPsychiatry, Albert Ludwigs University, Freiburg, Germany
    Epilepsy Behav 16:105-12. 2009
    ..Our finding supports a dimensional concept of the meaning of brain alterations and validates the clinical concept of dysphoric disorder of epilepsy...
  5. doi request reprint Local area network inhibition: a model of a potentially important paraepileptic pathomechanism in neuropsychiatric disorders
    Ludger Tebartz van Elst
    Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    Epilepsy Behav 22:231-9. 2011
    ..The LANI hypothesis is capable of explaining the complex relationship between EEG abnormalities and clinical symptoms in different neuropsychiatric syndromes and can be verified and falsified in empirical research...
  6. ncbi request reprint Evidence of disturbed amygdalar energy metabolism in patients with borderline personality disorder
    L Tebartz van Elst
    South German Brain Imaging Center, and Department of Psychiatry and Psychotherapy, Medical School, Albert Ludwigs University Freiburg, Hauptstrasse 5, 79104 Freiburg, Germany
    Neurosci Lett 417:36-41. 2007
    ..This pilot study of simultaneous amygdalar morphometry and spectroscopy in BPD reveals a possible link between amygdalar volume loss, psychopathology and neurochemical abnormalities in terms of creatine signals...
  7. doi request reprint The psychosocial impact of epilepsy in older people
    Ludger Tebartz van Elst
    Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstr 5, 79104 Freiburg, Germany
    Epilepsy Behav 15:S17-9. 2009
    ..In particular, we focus on the specific psychosocial impact that epilepsy has on the life of older people and their carers...
  8. pmc Chronic insomnia and MRI-measured hippocampal volumes: a pilot study
    Dieter Riemann
    Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstr 5, D 79104 Germany
    Sleep 30:955-8. 2007
    ..Morphometric analysis of magnetic resonance imaging brain scans was used to investigate possible neuroanatomic differences between patients with primary insomnia compared to good sleepers...
  9. doi request reprint Reduced interhemispheric structural connectivity between anterior cingulate cortices in borderline personality disorder
    NICOLAS RUSCH
    Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    Psychiatry Res 181:151-4. 2010
    ..Decreased interhemispheric structural connectivity between both ACCs may be a structural correlate of BPD...
  10. doi request reprint Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder
    NICOLAS RUSCH
    Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
    World J Biol Psychiatry 11:372-81. 2010
    ..Borderline personality disorder (BPD) is associated with structural and functional brain changes. Recent models and findings refer to alterations of glutamate and total N-acetylaspartate (tNAA) in this condition...
  11. doi request reprint Magnetic resonance spectroscopy of the anterior cingulate cortex in eating disorders
    Andreas A B Joos
    University of Freiburg, Department of Psychosomatic Medicine and Psychotherapy, Freiburg, Germany
    Psychiatry Res 191:196-200. 2011
    ....
  12. ncbi request reprint Frontolimbic glutamate alterations in first episode schizophrenia: evidence from a magnetic resonance spectroscopy study
    Hans M Olbrich
    Section for Experimental NeuroPsychiatry, Department of Psychiatry, Albert Ludwigs University, Freiburg, Germany
    World J Biol Psychiatry 9:59-63. 2008
    ..Absolute-quantification [1H]MRS can reveal glutamatergic abnormalities which might play an important role in the pathogenesis and course of schizophrenia...
  13. ncbi request reprint Frontocingular dysfunction in bulimia nervosa when confronted with disease-specific stimuli
    Andreas A B Joos
    University of Freiburg, Department of Psychosomatic Medicine and Psychotherapy, Freiburg, Germany
    Eur Eat Disord Rev 19:447-53. 2011
    ..Bulimia nervosa (BN) is characterized by dysregulation of impulse control, in other words, uncontrolled eating. Functional neuroimaging studies have been sparse and have used variable methodologies...
  14. pmc Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorder
    Evgeniy Perlov
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
    J Psychiatry Neurosci 33:509-15. 2008
    ..We sought to test the hypothesis that, like in pediatric patients, there might be hippocampus and amygdala volume abnormalities in adult patients with ADHD...
  15. doi request reprint Voxel-based morphometry in eating disorders: correlation of psychopathology with grey matter volume
    Andreas Joos
    Department of Psychosomatic Medicine and Psychotherapy, University of Freiburg, Hauptstrasse 8, Freiburg, Germany
    Psychiatry Res 182:146-51. 2010
    ....
  16. pmc Clarifying the role of the rostral dmPFC/dACC in fear/anxiety: learning, appraisal or expression?
    Simon Maier
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg im Breisgau, Germany
    PLoS ONE 7:e50120. 2012
    ..We discuss the broader implications of this finding for our understanding of mPFC/ACC function in fear and in negative emotion more generally...
  17. doi request reprint Spectroscopic findings in attention-deficit/hyperactivity disorder: review and meta-analysis
    Evgeniy Perlov
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
    World J Biol Psychiatry 10:355-65. 2009
    ..In this paper we review published MRS results with respect to childhood, adolescence and adult ADHD...
  18. doi request reprint Small amygdala-high aggression? The role of the amygdala in modulating aggression in healthy subjects
    Swantje Matthies
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Freiburg, Germany
    World J Biol Psychiatry 13:75-81. 2012
    ..In order to better understand the physiological role of the amygdala in modulating aggressive behaviour we investigated the relationship between amygdala volumes and lifetime aggression in healthy subjects...
  19. doi request reprint Visual cortex abnormalities in adults with ADHD: a structural MRI study
    Johannes Ahrendts
    Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    World J Biol Psychiatry 12:260-70. 2011
    ..The aim of this study was to clarify the involvement of prefronto-striatal and posterior parietal areas in adult ADHD...
  20. doi request reprint Evaluation of the efficacy and effectiveness of a structured disorder tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trial
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Atten Defic Hyperact Disord 2:203-12. 2010
    ..The trial is funded by the German Federal Ministry of Research and Education (01GV0606) and is part of the German network for the treatment of ADHD in children and adults (ADHD-NET)...
  21. doi request reprint Extraction of prefronto-amygdalar pathways by combining probability maps
    Tobias Bracht
    Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
    Psychiatry Res 174:217-22. 2009
    ..We believe that our approach provides a promising tool to assess the integrity of specific structural connections in patients with neuropsychiatric disorders...
  22. ncbi request reprint Neurochemical and structural correlates of executive dysfunction in schizophrenia
    NICOLAS RUSCH
    Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    Schizophr Res 99:155-63. 2008
    ....
  23. ncbi request reprint Grey matter deficit in long-term recovered anorexia nervosa patients
    Andreas Joos
    Department of Psychosomatic Medicine and Psychotherapy, University of Freiburg, Freiburg, Germany
    Eur Eat Disord Rev 19:59-63. 2011
    ..Cerebral grey matter (GM) reduction has repeatedly been shown in anorexia nervosa (AN). Evidence concerning completeness of GM restitution in recovered patients is contradictory...
  24. doi request reprint Severity of childhood attention-deficit hyperactivity disorder--a risk factor for personality disorders in adult life?
    Swantje Matthies
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Hauptstr 5 D 79104, Freiburg, Germany
    J Pers Disord 25:101-14. 2011
    ..Applying the IPDE we confirmed a high number of PDs among adult ADHD patients. Our findings point to a higher vulnerability for the development of PDs in patients with severe childhood ADHD...
  25. pmc Corpus callosum abnormalities in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder
    NICOLAS RUSCH
    Rüsch, Zahn, Ebert, Tebartz van Elst Department of Psychiatry and Psychotherapy, University of Freiburg, and the South German Brain Imaging Center, Freiburg, Germany
    J Psychiatry Neurosci 32:417-22. 2007
    ..Recent models suggest impaired structural and functional connectivity in this condition. To investigate this, we studied the thickness of the corpus callosum, the largest connecting fibre bundle in the human brain...
  26. doi request reprint Amygdala hyperreactivity in restrictive anorexia nervosa
    Andreas A B Joos
    University of Freiburg, Department of Psychosomatic Medicine and Psychotherapy, Freiburg, Germany
    Psychiatry Res 191:189-95. 2011
    ..Disgust ratings correlated with the amygdala signal negatively, which points to the complex role of this structure within eating disorders...
  27. ncbi request reprint Cerebral correlates of muscle tone fluctuations in restless legs syndrome: a pilot study with combined functional magnetic resonance imaging and anterior tibial muscle electromyography
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University Hospital, Hauptstrasse 5, 79104 Freiburg, Germany
    Sleep Med 9:177-83. 2008
    ..To investigate the pathomechanism of the disorder further we recorded a surface electromyogram (EMG) of the anterior tibial muscle during functional magnetic resonance imaging (fMRI) in patients with idiopathic RLS...
  28. ncbi request reprint Automatic metaphor processing in adults with Asperger syndrome: a metaphor interference effect task
    Ismene Hermann
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstraße 5, 79104, Freiburg, Germany
    Eur Arch Psychiatry Clin Neurosci 263:S177-87. 2013
    ..The findings indicate intact automatic metaphor processing in AS and replicate previous findings on automatic metaphor processing in typically developing individuals. ..
  29. doi request reprint Psychiatric side-effects of bilateral deep brain stimulation for movement disorders
    Marcus Pinsker
    Division of Stereotactic and Functional Neurosurgery, Department of General Neurosurgery, Neurosurgical Clinic, University Medical Center Freiburg, Breisacher Straße 64, Freiburg, D 79106, Germany
    Acta Neurochir Suppl 117:47-51. 2013
    ..The present study investigated psychiatric comorbidity and postoperative effects of DBS of different targets on mood and psychological functions in 81 patients with a mean follow-up of 37 months...
  30. ncbi request reprint Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study
    Ludger Tebartz van Elst
    Department for Psychiatry, Albert Ludwigs University, Freiburg, Germany
    Biol Psychiatry 58:724-30. 2005
    ....
  31. ncbi request reprint Inferior frontal white matter microstructure and patterns of psychopathology in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder
    NICOLAS RUSCH
    Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    Neuroimage 35:738-47. 2007
    ....
  32. doi request reprint Effect of antidepressive therapy on retinal contrast processing in depressive disorder
    Emanuel Bubl
    Department of Psychiatry and Psychotherapy, Albert Ludwigs Universitat, Hauptstrasse 5, Freiburg, Germany
    Br J Psychiatry 201:151-8. 2012
    ..Recently, we reported a reduced retinal contrast gain in unmedicated and medicated patients with major depression...
  33. doi request reprint Orbitofrontal reward sensitivity and impulsivity in adult attention deficit hyperactivity disorder
    Gregor Wilbertz
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Germany
    Neuroimage 60:353-61. 2012
    ..Reward value processing difficulties in ADHD should be considered when assessing reward anticipation and emotional learning in research and applied settings...
  34. doi request reprint Psychiatric comorbidity in patients with pharmacoresistant focal epilepsy and psychiatric outcome after epilepsy surgery
    Sabine Hellwig
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
    Epilepsy Behav 23:272-9. 2012
    ..Symptoms in 48% of patients with preoperative affective syndromes and 60% of patients with DD remitted after surgery. Seizure freedom and improved psychosocial status predicted remission of preoperative psychopathology...
  35. doi request reprint Seeing gray when feeling blue? Depression can be measured in the eye of the diseased
    Emanuel Bubl
    Department of Psychiatry and Psychotherapy, Albert Ludwigs University of Freiburg, Freiburg, Germany
    Biol Psychiatry 68:205-8. 2010
    ..To find an objective correlate of reduced contrast perception, we measured the PERG in healthy control subjects and unmedicated and medicated patients with depression...
  36. doi request reprint Cerebellar volume is linked to cognitive function in temporal lobe epilepsy: a quantitative MRI study
    Sabine Hellwig
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
    Epilepsy Behav 28:156-62. 2013
    ....
  37. ncbi request reprint Voxel-based morphometry in unmedicated patients with restless legs syndrome
    Magdolna Hornyak
    Center for Sleep Research and Sleep Medicine, Department of Psychiatry and Psychotherapy, University Hospital, Freiburg, Germany
    Sleep Med 9:22-6. 2007
    ..To address this issue, we performed VBM in unmedicated RLS patients...
  38. ncbi request reprint Aripiprazole in patients with Tourette syndrome
    Emanuel Bubl
    Department of Psychiatry, Albert Ludwigs University, Freiburg, Germany
    World J Biol Psychiatry 7:123-5. 2006
    ..Furthermore, we discuss possible pharmacological mechanisms for the observed effects...
  39. ncbi request reprint Vision in depressive disorder
    Emanuel Bubl
    Department of Psychiatry and Psychotherapy, Albert Ludwigs Universitat, Freiburg, Germany
    World J Biol Psychiatry 10:377-84. 2009
    ..To test the hypothesis that altered dopaminergic neurotransmission plays a role in major depression we measured contrast sensitivity in patients with major depression and in healthy control subjects...
  40. ncbi request reprint Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study
    Ludger Tebartz van Elst
    Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
    Biol Psychiatry 54:163-71. 2003
    ..We measured limbic and prefrontal brain volumes to test the hypothesis that frontolimbic brain pathology might be associated with borderline personality disorder...
  41. ncbi request reprint Psychotherapy of attention deficit hyperactivity disorder in adults--a pilot study using a structured skills training program
    Bernd Hesslinger
    Albert Ludwigs University, Department of Psychiatry and Psychotherapy, Hauptstr 5, 79104 Freiburg, Germany
    Eur Arch Psychiatry Clin Neurosci 252:177-84. 2002
    ..This treatment resulted in positive outcomes in that patients improved on all psychometric scales...
  42. doi request reprint Management and health implications of epilepsy in older women
    Oliver Tüscher
    Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
    Maturitas 66:242-5. 2010
    ..Gender-specific issues such as the influence of perimenopausal hormonal changes, bone health and hormone replacement therapy are discussed...
  43. ncbi request reprint Attention deficit hyperactivity disorder in adults-early vs. late onset in a retrospective study
    Bernd Hesslinger
    Department of Psychiatry and Psychotherapy, Universitatsklinik Freiburg, Hauptstr 5, 79104 Freiburg, Germany
    Psychiatry Res 119:217-23. 2003
    ..In four of these patients (8% of the total sample), this assessment was confirmed by parent ratings. There was no difference between early onset and late onset ADHD groups in terms of psychopathology or psychiatric comorbidity...
  44. doi request reprint Grey matter deficit in long-term recovered anorexia nervosa patients
    Andreas Joos
    Department of Psychosomatic Medicine and Psychotherapy, University of Freiburg, Freiburg, Germany
    Eur Eat Disord Rev 19:59-63. 2011
    ..Cerebral grey matter (GM) reduction has repeatedly been shown in anorexia nervosa (AN). Evidence concerning completeness of GM restitution in recovered patients is contradictory...
  45. ncbi request reprint Structured group psychotherapy in adults with attention deficit hyperactivity disorder: results of an open multicentre study
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
    J Nerv Ment Dis 195:1013-9. 2007
    ..In this multicenter study, the therapy program showed therapist-independent effects and seemed to be disorder-specific. This warrants the effort of organizing further controlled studies...
  46. doi request reprint A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstrasse 5, 79104, Freiburg, Germany
    Atten Defic Hyperact Disord 6:35-47. 2014
    ....
  47. doi request reprint Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstrasse 5, 79104 Freiburg, Germany
    Neurocase 15:527-34. 2009
    ..Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula...
  48. ncbi request reprint Serum creatine kinase elevation as a possible complication of therapy with olanzapine
    Evgeniy Perlov
    Department Psychiatry and Psychotherapy, University Hospital of Freiburg, Hauptsrtasse 5, 79098, Freiburg, Germany
    Naunyn Schmiedebergs Arch Pharmacol 372:168-9. 2005