Research Topics
Genomes and Genes | N UlfigSummaryAffiliation: University of Rostock Country: Germany Publications
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Publications
Transient architectonic features in the basolateral amygdala of the human fetal brainN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Germany
Acta Anat (Basel) 163:99-112. 1998..A comparison of Nissl and vimentin preparations reveals that transient architectonic characteristics as visible in relatively thick Nissl sections may be correlated with migrational routes...
Effect of fetal hydrocephalus on the distribution patterns of calcium-binding proteins in the human occipital cortexN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Germany
Pediatr Neurosurg 34:20-32. 2001..On the whole, these neuronal alterations may account for residual deficits observed after shunting...
Expression of a kinase anchoring protein 79 and synaptophysin in the developing human red nucleusN Ulfig
Department of Anatomy, Neuroembryonic Research Laboratory, University of Rostock, Germany
Neurosignals 11:95-102. 2002..Our observations are mainly in line with connectivity data regarding the red nucleus...
Ganglionic eminence of the human fetal brain--new vistasNorbert Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, Faculty of Medicine, University of Rostock, Rostock, Germany
Anat Rec 267:191-5. 2002..The consequences of such bleedings are discussed in view of cellular responses, such as the induction of leukemia inhibitory factor (LIF) expression in GE cells after hemorrhage...
Calcium-binding proteins in the human developing brainN Ulfig
Institut für Anatomie der Universität Rostock, Gertrudenstr 9, 18057 Rostock, Germany
Adv Anat Embryol Cell Biol 165:III-IX, 1-92. 2002..The transient structures are sites of predilection for alteration caused by hypoxia-ischemia, hemorrhage, or hydrocephalus...
The ganglionic eminence--a putative intermediate target of amygdaloid connectionsNorbert Ulfig
RG Neuroembryology, Department of Anatomy, University of Rostock, Gertrudenstr 9, D 18055 Rostock, Germany
Brain Res Dev Brain Res 139:313-8. 2002..These results provide the first evidence that the marginal zone of the inferior ganglionic eminence is likely to constitute an intermediate target for growing axons which belong the amygdaloid projection to the entorhinal cortex...
Ontogeny of the human amygdalaNorbert Ulfig
RG Neuroembryology, Department of Anatomy, University of Rostock, D 18055 Rostock, Germany
Ann N Y Acad Sci 985:22-33. 2003..The aforementioned results provide a basis for investigations on subtle changes in pathologically altered material, such as hemorrhage, in the ganglionic eminence of preterm infants...
Brain macrophages and microglia in human fetal hydrocephalusNorbert Ulfig
Neuroembryonic Research Laboratory, Institute of Anatomy, University of Rostock, Gertrudenstrasse 9, D 18055 Rostock, Germany
Brain Dev 26:307-15. 2004..The macrophage response detected at the ependymal lining of the ventricles and within the periventricular area in hydrocephalus may be related both to the severity of hydrocephalus and the age of the fetus...
Expression of connexin 26 in the ganglionic eminence of preterm infants after bleedingsNorbert Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, Faculty of Medicine, University of Rostock, Gertrudenstr 9, D 18055 Rostock, Germany
Neurosci Res 50:125-8. 2004..In controls, no positive cells are present. It is discussed that an increase of gap junctional communication may result in spreading of the primary injury...
Expression patterns of PSA-NCAM in the human ganglionic eminence and its vicinity: role of PSA-NCAM in neuronal migration and axonal growth?Norbert Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Rostock, Germany
Cells Tissues Organs 177:229-36. 2004..Our results suggest a close relationship between PSA-NCAM expression and neuronal migration (over short distances) and transitory axonal projections (target recognition and axonal fasciculation) in the region of the GE...
Expression of ARVCF in the human ganglionic eminence during fetal developmentNorbert Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Rostock, Germany
Dev Neurosci 26:38-44. 2004..Our results implicate a very close association of ARVCF with migrating neurons from the GE...
Evidence for the presence of the sphingosine-1-phosphate receptor Edg-8 in human radial glial fibersNorbert Ulfig
Department of Anatomy, Neuroembryonic Research Laboratory, University of Rostock, Gertrudenstrasse 9, D 18055 Rostock, Germany
Acta Histochem 106:373-8. 2004..The findings indicate that sphingosine-1-phosphate may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells...
Development-related expression of AKAP79 in the striatal compartments of the human brainN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Germany
Cells Tissues Organs 168:319-29. 2001..This discrepancy might indicate that a subpopulation of matrix neurons may, despite dopaminergic input, not express AKAP79...
Differential expression of calcium-binding proteins in the red nucleus of the developing and adult human brainN Ulfig
Department of Anatomy, University of Rostock, Germany
Anat Embryol (Berl) 203:95-108. 2001....
Transient features of the thalamic reticular nucleus in the human foetal brainN Ulfig
Department of Anatomy, Neuroembryonic Research Laboratory, University of Rostock, Germany
Eur J Neurosci 10:3773-84. 1998..Moreover, the RN may serve as an intermediate target for growing axons which are sorted and directed towards different final targets...
Immunolabelling of spliceosomes in sections and cultured astrocytes of human fetal brain tissueN Ulfig
Department of Anatomy, University of Rostock, Germany
Brain Dev 21:51-8. 1999..The in vitro finding indicates that anti-SC35 may well be used as a tool to study possible alterations of the speckles after, for instance, application of growth factors...
Alterations in the organization of the isocortical layer I in trisomy 22N Ulfig
Department of Anatomy, University of Rostock, Germany
Neurosci Res 33:119-25. 1999..In trisomy 22 the isocortical layer I reveals malpositioned axonal plexus and a corresponding displacement of synaptic proteins. The possible significance of this alteration in the developmental process of the isocortex is discussed...
Expression of a kinase anchoring protein 79 in the human fetal amygdalaN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Rostock, Germany
Microsc Res Tech 46:48-52. 1999..The widespread distribution of AKAP79 indicates its possible role in various amygdaloid circuitries; thus, AKAP79 does not seem to be restricted to definite functional systems in the 8th month...
Interleukin-6 receptor is highly expressed in the ganglionic eminence of the human fetal brainN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Germany
Biol Neonate 76:320-4. 1999..IL-6 may activate the immature IL-6R-positive cells to secrete a protease which is likely to be involved in GE involution and, perhaps, in the development of hemorrhage frequently occurring in the GE of premature infants...
Changing distribution patterns of synaptophysin-immunoreactive structures in the human dorsal striatum of the fetal brainN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, D 18055 Rostock, Federal Republic of Germany
Anat Rec 258:198-209. 2000..The changeover from patchy to homogeneous SYN immunolabelling takes place distinctly earlier than changes in the distribution of other neuroactive substances described before...
Differential activation of mononuclear phagocytes in cerebellar malformation associated with Walker-Warburg syndromeNorbert Ulfig
Neuroembryonic Research Laboratory, Institute of Anatomy, University of Rostock, Rostock, Germany
Neuropathology 28:333-40. 2008..In this case report, we present evidence for focal and differential activation of mononuclear phagocytes specifically confined to the dysplastic cerebellum of an infant at 5 months of age, diagnosed with WWS...
Transient structures of the human fetal brain: subplate, thalamic reticular complex, ganglionic eminenceN Ulfig
Department of Anatomy, University of Rostock, Germany
Histol Histopathol 15:771-90. 2000..The characteristics of the three transient structures are particularly relevant for developmental neuropathology as these structures may be damaged in disorders that preferentially occur in preterm infants...
Transient expression of synaptogyrin in the ganglionic eminence of the human fetal brainN Ulfig
Department of Anatomy, University of Rostock, Germany
Ann Anat 182:505-8. 2000..The synaptogyrin-immunoreactive GE-cells may form an early corticopedal connection which provides a scaffold for outgrowing cortical axons...
Expression of leukemia inhibitory factor in the ganglionic eminence of the human fetal brain after bleedingsN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Gertrudenstrasse 9, D 18055 Rostock, Germany
Neurosci Lett 299:153-5. 2001..The expression of LIF in cases with bleedings may interfere with normal developmental processes taking place within the ganglionic eminence...
Expression of MAP1a and MAP1b in the ganglionic eminence and the internal capsule of the human fetal brainN Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Gertrudenstr 9, D 18055 Rostock, Germany
Neurosci Res 38:397-405. 2000..The short MAP1b fiber bundles found in the IC are in accordance with cell culture experiments showing that MAP1b is concentrated in distal parts of outgrowing axons...
Distribution of GAP-43-immunoreactive structures in the human fetal amygdalaN Ulfig
Department of Anatomy, University of Rostock, Germany
Eur J Histochem 43:19-28. 1999..In general, anti-GAP-43 has been shown to be an appropriate tool to investigate axonal growth and synaptogenesis in the developing human brain...
Expression of calbindin and calretinin in the human ganglionic eminenceN Ulfig
Department of Anatomy, Neuroembryonic Research Laboratory, University of Rostock, Gertrudenstr. 9, 18055 Rostock, Germany
Pediatr Neurol 24:357-60. 2001..The findings are discussed with regard to central nervous system complications in preterm infants involving the ganglionic eminence...
Anomalous alterations affecting microglia in the central nervous system of a fetus at 12 weeks of gestation: case reportPayam Rezaie
Neuroembryonic Research Laboratory, Institute of Anatomy, University of Rostock, Gertrudenstrasse 9, 18055 Rostock, Germany
Acta Neuropathol 107:176-80. 2004....
Nitric oxide donor sodium nitroprusside dilates rat small arteries by activation of inward rectifier potassium channelsRudolf Schubert
Institute of Physiology, University Rostock, Rostock, Germany
Hypertension 43:891-6. 2004..3 and 2.4, were found. However, only K(IR) 2.1 antibodies immunostained the tunica media of the vessel. These data suggest that vascular smooth muscle K(IR) 2.1 channels are involved in the SNP-induced dilation of rat-tail small arteries...
Neuronal vacuolation in the basal nucleus of meynert caused by fetal hydrocephalusNorbert Ulfig
Neuroembryonic Research Laboratory, Department of Anatomy, University of Rostock, Gertrudenstrasse 9, D-18055 Rostock, Germany
Pediatr Neurosurg 36:320-3. 2002..The neuronal alterations in the basal nucleus may account at least in part for residual deficits observed after shunt placement...
Volume, neuron density and total neuron number in five subcortical regions in schizophreniaPawel Kreczmanski
Department of Psychiatry and Neuropsychology, Division of Cellular Neuroscience, Maastricht University, Maastricht, The Netherlands
Brain 130:678-92. 2007....
SMN, the product of the spinal muscular atrophy-determining gene, is expressed widely but selectively in the developing human forebrainMichael Briese
MRC Functional Genetics Unit, Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, Oxford OX1 3QX, United Kingdom
J Comp Neurol 497:808-16. 2006..These findings provide an anatomical basis for future investigations of SMN functions during brain development and for the neuropathological characterization of severe SMA cases...
Microglia in the cerebral wall of the human telencephalon at second trimesterPayam Rezaie
Department of Biological Sciences, Faculty of Science, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK
Cereb Cortex 15:938-49. 2005..These findings are discussed in relation to developmental events that take place during the second trimester within the wall of the telencephalon...
Detection of hypothetical proteins in human fetal perireticular nucleusFelix Hepner
Department of Pediatrics, Medical University of Vienna, Austria
J Proteome Res 4:2379-85. 2005..The existence of formerly HP proteins in the PN of human fetal brain is shown, thus extending knowledge of the brain proteome and proposing the method used as a suitable analytical tool for searching HP...
Mean cell spacing abnormalities in the neocortex of patients with schizophreniaManuel F Casanova
Department of Psychiatry and Behavioral Sciences, University of Louisville, 500 South Preston Street, A Building, Room 217, Louisville, KY 40292, USA
Psychiatry Res 133:1-12. 2005..The lack of variation in the columnarity index argues in favor of a defect postdating the formation of the cell minicolumn...
Fetal and early post-natal development of the human spleen: from primordial arterial B cell lobules to a non-segmented organBirte Steiniger
Institute of Anatomy and Cell Biology, University of Marburg, Robert Koch Str 8, 35037, Marburg, Germany
Histochem Cell Biol 128:205-15. 2007..CCL21, on the contrary, was only demonstrated in fibroblast-like cells supporting T cell clusters from stage II onwards...
Hypothesis on the delayed occurrence of diplegia in infants with periventricular leukomalaciaNorbert Ulfig
Brain Dev 24:787. 2002
