Tobias Traeger

Summary

Affiliation: University of Greifswald
Country: Germany

Publications

  1. pmc Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis
    Tobias Traeger
    Department of Surgery, Ernst Moritz Arndt Universitat Greifswald, Greifswald, Germany
    Infect Immun 76:5285-93. 2008
  2. ncbi request reprint Kupffer cell depletion reduces hepatic inflammation and apoptosis but decreases survival in abdominal sepsis
    Tobias Traeger
    Department of Surgery, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Eur J Gastroenterol Hepatol 22:1039-49. 2010
  3. ncbi request reprint Selective depletion of alveolar macrophages in polymicrobial sepsis increases lung injury, bacterial load and mortality but does not affect cytokine release
    Tobias Traeger
    Department of Surgery, University of Greifswald, Greifswald, Germany
    Respiration 77:203-13. 2009
  4. doi request reprint Implantation of alloplastic material increases survival of mice subsequently exposed to polymicrobial sepsis
    Wolfram Kessler
    Klinik für Allgemeine Chirurgie, Visceral, Thorax und Gefässchirurgie der Ernst Moritz Arndt Universität Greifswald, Friedrich Loeffler Str 23b, 17457, Greifswald, Germany
    Langenbecks Arch Surg 395:157-62. 2010
  5. ncbi request reprint Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis
    Stefan Maier
    Department of Surgery, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Shock 21:505-11. 2004
  6. ncbi request reprint The vagal nerve as a link between the nervous and immune system in the instance of polymicrobial sepsis
    Wolfram Kessler
    Department of Surgery, Abteilung für Allgemeine Chirurgie, Visceral Thorax und Gefässchirurgie, Universitätsklinikum Greifswald der Ernst Moritz Arndt Universität, Friedrich Loeffler Strasse 23b, 17475, Greifswald, Germany
    Langenbecks Arch Surg 391:83-7. 2006
  7. doi request reprint Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) improves the innate immune response and enhances survival in murine polymicrobial sepsis
    Katharina Cziupka
    Department of Surgery, Ernst Moritz Arndt University Greifswald, Germany
    Crit Care Med 38:2169-74. 2010
  8. ncbi request reprint CCR4-deficient mice show prolonged graft survival in a chronic cardiac transplant rejection model
    Norbert Hüser
    Department of Surgery, Technische Universitat Munchen, Munich, Germany
    Eur J Immunol 35:128-38. 2005
  9. ncbi request reprint Sepsis affects cardiac expression of multidrug resistance protein 5 (MRP5, ABCC5), an ABC-type CGMP export pump
    Konrad Meissner
    Klinik für Anästhesiologie und Intensivmedizin, Ernst Moritz Arndt Universitat Greifswald, Greifswald, Germany
    Shock 28:564-9. 2007
  10. ncbi request reprint Seasonal variations in inflammatory responses to sepsis and stress in mice
    Cornelia Kiank
    Departments of Immunology, University of Greifswald, Greifswald, Germany
    Crit Care Med 35:2352-8. 2007

Collaborators

Detail Information

Publications13

  1. pmc Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis
    Tobias Traeger
    Department of Surgery, Ernst Moritz Arndt Universitat Greifswald, Greifswald, Germany
    Infect Immun 76:5285-93. 2008
    ..Thus, our data provide clear evidence that CCR4 plays a strictly detrimental role in the course of polymicrobial sepsis...
  2. ncbi request reprint Kupffer cell depletion reduces hepatic inflammation and apoptosis but decreases survival in abdominal sepsis
    Tobias Traeger
    Department of Surgery, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Eur J Gastroenterol Hepatol 22:1039-49. 2010
    ..This study evaluates the impact of selective KC depletion on hepatic microcirculation, cytokine release, and systemic alterations in the colon ascendens stent peritonitis (CASP), a model of polymicrobial abdominal sepsis...
  3. ncbi request reprint Selective depletion of alveolar macrophages in polymicrobial sepsis increases lung injury, bacterial load and mortality but does not affect cytokine release
    Tobias Traeger
    Department of Surgery, University of Greifswald, Greifswald, Germany
    Respiration 77:203-13. 2009
    ..It has been postulated that AM are involved in the development of acute local disorders as a consequence of extrapulmonary stimuli like pancreatitis, peritonitis, or trauma...
  4. doi request reprint Implantation of alloplastic material increases survival of mice subsequently exposed to polymicrobial sepsis
    Wolfram Kessler
    Klinik für Allgemeine Chirurgie, Visceral, Thorax und Gefässchirurgie der Ernst Moritz Arndt Universität Greifswald, Friedrich Loeffler Str 23b, 17457, Greifswald, Germany
    Langenbecks Arch Surg 395:157-62. 2010
    ..Major surgery can modulate the immune system and by this the clinical course of following complications. Effects of minor surgical treatments on the immune system and septic complications are poorly understood...
  5. ncbi request reprint Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis
    Stefan Maier
    Department of Surgery, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Shock 21:505-11. 2004
    ..In contrast, CLP reveals a model of intra-abdominal abscess formation with sustained and minor signs of systemic inflammation...
  6. ncbi request reprint The vagal nerve as a link between the nervous and immune system in the instance of polymicrobial sepsis
    Wolfram Kessler
    Department of Surgery, Abteilung für Allgemeine Chirurgie, Visceral Thorax und Gefässchirurgie, Universitätsklinikum Greifswald der Ernst Moritz Arndt Universität, Friedrich Loeffler Strasse 23b, 17475, Greifswald, Germany
    Langenbecks Arch Surg 391:83-7. 2006
    ..This connection is called the "cholinergic inflammatory pathway." Through stimulation of the acetylcholine receptors located upon the macrophages, the "unspecific" immune system can be directly influenced...
  7. doi request reprint Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) improves the innate immune response and enhances survival in murine polymicrobial sepsis
    Katharina Cziupka
    Department of Surgery, Ernst Moritz Arndt University Greifswald, Germany
    Crit Care Med 38:2169-74. 2010
    ..TRAIL is commonly known as an apoptosis-inducing agent in cancer cells. It also plays an important role in the regulation of inflammatory reactions. The role of TRAIL in polymicrobial sepsis is still unclear...
  8. ncbi request reprint CCR4-deficient mice show prolonged graft survival in a chronic cardiac transplant rejection model
    Norbert Hüser
    Department of Surgery, Technische Universitat Munchen, Munich, Germany
    Eur J Immunol 35:128-38. 2005
    ..These findings indicate that CCR4 is involved in the recruitment of NK1.1(+)CD3(+) cells into cardiac allografts and clearly establish an important and novel role for CCR4 in chronic graft rejection...
  9. ncbi request reprint Sepsis affects cardiac expression of multidrug resistance protein 5 (MRP5, ABCC5), an ABC-type CGMP export pump
    Konrad Meissner
    Klinik für Anästhesiologie und Intensivmedizin, Ernst Moritz Arndt Universitat Greifswald, Greifswald, Germany
    Shock 28:564-9. 2007
    ..Reduced cGMP export as a consequence of decreased MRP5 expression can attenuate heart failure in sepsis...
  10. ncbi request reprint Seasonal variations in inflammatory responses to sepsis and stress in mice
    Cornelia Kiank
    Departments of Immunology, University of Greifswald, Greifswald, Germany
    Crit Care Med 35:2352-8. 2007
    ..In this study, we analyzed seasonal variations of immunoreactivity using a model of septic shock and a model of immunosuppression induced by chronic stress in mice...
  11. doi request reprint Intraarterial recombinant tissue plasminogen activator thrombolysis of acute and semiacute lower limb arterial occlusion: quality assurance, complication management, and 12-month follow-up reinterventions
    Jens Peter Kuhn
    Department of Diagnostic Radiology and Neuroradiology, Ernst Moritz Arndt University, Greifswald, Germany
    AJR Am J Roentgenol 196:1189-93. 2011
    ..The purpose of this study is to assess the efficacy of intraarterial thrombolysis in acute and semiacute occlusions of the lower limb...
  12. ncbi request reprint Impact of interleukin-12, oxidative burst, and iNOS on the survival of murine fecal peritonitis
    Markus Entleutner
    Chirurgische Klinik und Poliklinik, Technischen Universitat Munchen, Munich, Germany
    Int J Colorectal Dis 21:64-70. 2006
    ..Overall, these findings suggest that IL-12 deficiency causes a profound delay of the immune response after polymicrobial challenge resulting in significantly increased susceptibility in the CASP model...