Affiliation: University of Regensburg
- Increased hypothalamic expression of prolactin in lactation: involvement in behavioural and neuroendocrine stress responsesLuz Torner
Institute of Zoology, University of Regensburg, Universitätsstr 31, 93053 Regensburg, Germany
Eur J Neurosci 15:1381-9. 2002....
- In vivo release and gene upregulation of brain prolactin in response to physiological stimuliLuz Torner
University of Regensburg, Institute of Zoology, Universitatsstrasse 31, 93053 Regensburg, Germany
Eur J Neurosci 19:1601-8. 2004..This is the first demonstration of stimulus-induced, locally restricted release and gene upregulation of PRL within the brain, emphasizing the involvement of this 'novel' neuropeptide in various brain functions...
- Prolactin induces Egr-1 gene expression in cultured hypothalamic cells and in the rat hypothalamusAnnegret Blume
Department of Behavioural and Molecular Neuroendocrinology, Institute of Zoology, University of Regensburg, Regensburg, Germany
Brain Res 1302:34-41. 2009..The data suggest that PRL modulates plasticity in oxytocinergic neurons, through MAP kinase-dependent induction of Egr-1...
- Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neuronsAnnegret Blume
Department of Behavioural and Molecular Neuroendocrinology, Institute of Zoology, University of Regensburg, 93053 Regensburg, Germany
Endocrinology 150:1841-9. 2009..In addition, the prominent stimulatory action of PRL on the ERK/MAPK pathway in the hypothalamic PVN and supraoptic nucleus is likely to mediate neuroplasticity of the neuroendocrine system during lactation...
- Low inborn anxiety correlates with high intermale aggression: link to ACTH response and neuronal activation of the hypothalamic paraventricular nucleusAlexa H Veenema
Department of Behavioral Neuroendocrinology, Institute of Zoology, University of Regensburg, Universitaetsstrasse 31, 93053 Regensburg, Germany
Horm Behav 51:11-9. 2007..Furthermore, the increased neuronal activation of the PVN along with the higher ACTH responsiveness might underlie the display of high aggression...
- Oxytocin reduces anxiety via ERK1/2 activation: local effect within the rat hypothalamic paraventricular nucleusAnnegret Blume
Department of Behavioural and Molecular Neuroendocrinology, Institute of Zoology, University of Regensburg, Germany
Eur J Neurosci 27:1947-56. 2008..Thus, OTR agonism or activation of the ERK1/2 cascade, specifically within the hypothalamus, may provide therapeutically relevant mechanisms...
- Oxytocin actions within the supraoptic and paraventricular nuclei: differential effects on peripheral and intranuclear vasopressin releaseInga D Neumann
Institute of Zoology, Department of Behavioural Neuroendocrinology, University of Regensburg, Resenburg, Germany
Am J Physiol Regul Integr Comp Physiol 291:R29-36. 2006..Further, while exerting an inhibitory effect on hypothalamo-pituitary-adrenal axis activity under basal conditions, hypothalamic OXT is essential for an adequate acute ACTH response...
- Prolactin prevents chronic stress-induced decrease of adult hippocampal neurogenesis and promotes neuronal fateLuz Torner
Department of Behavioral and Molecular Neuroendocrinology, Institute of Zoology, University of Regensburg, 93053 Regensburg, Germany
J Neurosci 29:1826-33. 2009..Cell fate analysis revealed a higher percentage of neurons in PRL- compared with vehicle-treated stressed mice. The results demonstrate that PRL protects neurogenesis in the DG of chronically stressed mice and promotes neuronal fate...
- The brain prolactin system: involvement in stress response adaptations in lactationLuz Torner
University of Regensburg, Institute of Zoology, Universitätsstr 31, Germany
Stress 5:249-57. 2002..The hypothesis of a brain prolactin system activated in the peripartum period which contributes to the adaptive changes in stress responsiveness in order to support reproductive functions is strongly emphasised...