P Thomas

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi request reprint Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation
    P Thomas
    Department of Dermatology and Allergology, Ludwig Maximilians University Munich, Frauenlobstr 9 11, Munich 80337, Germany
    Allergy 64:1157-65. 2009
  2. pmc Allergy or tolerance: reduced inflammatory cytokine response and concomitant IL-10 production of lymphocytes and monocytes in symptom-free titanium dental implant patients
    Peter Thomas
    Department of Dermatology and Allergology, Ludwig Maximilians University of Munich, Frauenlobstraße 9 11, 80337 Munich, Germany
    Biomed Res Int 2013:539834. 2013
  3. ncbi request reprint [Characteristics of 200 patients with suspected implant allergy compared to 100 symptom-free arthroplasty patients]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität München, Frauenlobstr 9 11, 80337, Munchen, Deutschland
    Orthopade 42:607-13. 2013
  4. ncbi request reprint [Allergy diagnostics in suspected metal implant intolerance]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität München, Frauenlobstr 9 11, 80337, Munchen, Deutschland
    Orthopade 42:602-6. 2013
  5. ncbi request reprint Hypersensitivity to titanium osteosynthesis with impaired fracture healing, eczema, and T-cell hyperresponsiveness in vitro: case report and review of the literature
    Peter Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität, Munchen, Germany
    Contact Dermatitis 55:199-202. 2006
  6. ncbi request reprint [Orthopedic surgical implants and allergies. Joint statement by the Implant Allergy Working Group (AK 20) of the DGOOC (German Association of Orthopedics and Orthopedic Surgery), DKG (German Contact Dermatitis Research Group) and DGAKI (German Society for
    P Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München
    Hautarzt 59:220-9. 2008
  7. ncbi request reprint [Orthopedic surgical implants and allergies: joint statement by the implant allergy working group (AK 20) of the DGOOC (German association of orthopedics and orthopedic surgery), DKG (German contact dermatitis research group) and dgaki (German society for
    P Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München, Frauenlobstrasse 9 11, 80337 München, Deutschland
    Orthopade 37:75-88. 2008
  8. doi request reprint [Allergy to bone cement components]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, 80337, Munchen, Deutschland
    Orthopade 37:117-20. 2008
  9. doi request reprint [Allergy diagnostics in implant intolerance]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, 80337, Munchen, Deutschland
    Orthopade 37:131-5. 2008
  10. ncbi request reprint [Lice, scabies and fleas in children]
    Peter Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen
    MMW Fortschr Med 150:31-2. 2008

Collaborators

Detail Information

Publications31

  1. doi request reprint Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation
    P Thomas
    Department of Dermatology and Allergology, Ludwig Maximilians University Munich, Frauenlobstr 9 11, Munich 80337, Germany
    Allergy 64:1157-65. 2009
    ..In 16 patients with revised metal-on-metal arthroplasty and peri-implant lymphocytic inflammation, we verified the role of metal hypersensitivity by patch testing (PT) and lymphocyte transformation test (LTT)...
  2. pmc Allergy or tolerance: reduced inflammatory cytokine response and concomitant IL-10 production of lymphocytes and monocytes in symptom-free titanium dental implant patients
    Peter Thomas
    Department of Dermatology and Allergology, Ludwig Maximilians University of Munich, Frauenlobstraße 9 11, 80337 Munich, Germany
    Biomed Res Int 2013:539834. 2013
    ..Thus in vitro IL-1 β -, IL-6-, and TNF- α production reflects "normal" unspecific immune response to Ti. This might be reduced by production of tolerogenic IL-10 in individuals with symptom-free Ti dental implants. ..
  3. ncbi request reprint [Characteristics of 200 patients with suspected implant allergy compared to 100 symptom-free arthroplasty patients]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität München, Frauenlobstr 9 11, 80337, Munchen, Deutschland
    Orthopade 42:607-13. 2013
    ....
  4. ncbi request reprint [Allergy diagnostics in suspected metal implant intolerance]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität München, Frauenlobstr 9 11, 80337, Munchen, Deutschland
    Orthopade 42:602-6. 2013
    ..Additional information on a scientific level is given by the lymphocyte transformation test (LTT) assessing metal sensitivity and by peri-implant molecular cytokine profiling giving the inflammatory pattern. ..
  5. ncbi request reprint Hypersensitivity to titanium osteosynthesis with impaired fracture healing, eczema, and T-cell hyperresponsiveness in vitro: case report and review of the literature
    Peter Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität, Munchen, Germany
    Contact Dermatitis 55:199-202. 2006
    ..Parallel to this, in vitro hyperreactivity to titanium disappeared. Although contact allergic reactions to titanium have been very rarely reported, these findings support a diagnosis of titanium allergy in our patient...
  6. ncbi request reprint [Orthopedic surgical implants and allergies. Joint statement by the Implant Allergy Working Group (AK 20) of the DGOOC (German Association of Orthopedics and Orthopedic Surgery), DKG (German Contact Dermatitis Research Group) and DGAKI (German Society for
    P Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München
    Hautarzt 59:220-9. 2008
    ..If a regular, potentially applicable CoCr/PE articulation is preferred, the patient must be well informed and must give his/her written consent...
  7. ncbi request reprint [Orthopedic surgical implants and allergies: joint statement by the implant allergy working group (AK 20) of the DGOOC (German association of orthopedics and orthopedic surgery), DKG (German contact dermatitis research group) and dgaki (German society for
    P Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München, Frauenlobstrasse 9 11, 80337 München, Deutschland
    Orthopade 37:75-88. 2008
    ..If a regular, potentially applicable CoCr/PE articulation is preferred, the patient must be well informed and must give his/her written consent...
  8. doi request reprint [Allergy to bone cement components]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, 80337, Munchen, Deutschland
    Orthopade 37:117-20. 2008
    ..8%) and BPO (8.0%). The clinical significance of test results cannot always be shown, but we still recommend including bone cement components in the allergological diagnostics of suspected hypersensitivity reactions to arthroplasty...
  9. doi request reprint [Allergy diagnostics in implant intolerance]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, 80337, Munchen, Deutschland
    Orthopade 37:131-5. 2008
    ..Identification of histological allergy characteristics and evaluation of the lymphocyte transformation test beyond indications of sensitization will be possible only when larger studies are available...
  10. ncbi request reprint [Lice, scabies and fleas in children]
    Peter Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen
    MMW Fortschr Med 150:31-2. 2008
  11. doi request reprint [Implant allergies]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstr 9 11, 80337, Munchen
    Hautarzt 61:255-62; quiz 263-4. 2010
    ..If the regular CoCr-polyethylene articulation is employed, the patient should give informed written consent...
  12. ncbi request reprint [Allergy towards bone cement]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, 80337, Munchen
    Orthopade 35:956, 958-60. 2006
    ..Therefore, in the case of suspected hypersensitivity reactions to arthroplasty, the allergological diagnostics should include bone cement components...
  13. ncbi request reprint Osteosynthesis associated contact dermatitis with unusual perpetuation of hyperreactivity in a nickel allergic patient
    P Thomas
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München, Munchen, Germany
    Contact Dermatitis 54:222-5. 2006
  14. doi request reprint [Implant allergy register--a first report]
    R Eben
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Frauenlobstrasse 9 11, 80337, Munchen, Deutschland
    Orthopade 38:557-62. 2009
    ..There are case reports about patients with metal implant allergy. However, large-scale observations regarding frequency and elicitors are lacking...
  15. ncbi request reprint Immuno-allergological properties of aluminium oxide (Al2O3) ceramics and nickel sulfate in humans
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, D 80337 München, Germany
    Biomaterials 24:959-66. 2003
    ..Cellular reactivity of nickel allergic and non-allergic donors was partly enhanced upon contact to Al(2)O(3) disks...
  16. ncbi request reprint Molecular analysis of T-cell clonality with concomitant specific T-cell proliferation in vitro in nickel-allergic individuals
    B Summer
    , , Frauenlobstr. 9-11, D-80337 Munich, Germany
    Allergy 56:767-70. 2001
    ....
  17. ncbi request reprint Erythema induratum of Bazin. Evidence of T-lymphocyte hyperresponsiveness to purified protein derivative of tuberculin: report of two cases and treatment
    M W Ollert
    Department of Dermatology, Ludwig Maximilians Universitat, Munich, Germany
    Arch Dermatol 129:469-73. 1993
    ....
  18. ncbi request reprint [Allergic reactions to implant materials]
    P Thomas
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Munich
    Orthopade 32:60-4. 2003
    ....
  19. doi request reprint [Contact allergy to metals and bone cement components in patients with intolerance of arthroplasty]
    R Eben
    Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig Maximilians Universität München
    Dtsch Med Wochenschr 135:1418-22. 2010
    ..There is no investigation in a large patient series giving data about the frequency of allergic reactions to metals or bone cement components in arthroplasty with complications...
  20. ncbi request reprint Targeted treatment of pyoderma gangrenosum in PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra
    M Brenner
    Department of Dermatology, Ludwig Maximilian University of Munich, D 80337 Munich, Germany
    Br J Dermatol 161:1199-201. 2009
    ..We report the rapid and lasting response of pyoderma gangrenosum to the targeted treatment with the recombinant human interleukin-1 receptor antagonist (rHuIL-1Ra) anakinra in a patient with PAPA syndrome...
  21. doi request reprint Nickel (Ni) allergic patients with complications to Ni containing joint replacement show preferential IL-17 type reactivity to Ni
    Burkhard Summer
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Munchen, Germany
    Contact Dermatitis 63:15-22. 2010
    ..Some nickel (Ni) allergic patients develop complications following Ni-containing arthroplasty. In the peri-implant tissue of such patients, we had observed lymphocyte dominated inflammation together with IFN-gamma and IL-17 expression...
  22. doi request reprint Intolerance reactions to knee arthroplasty in patients with nickel/cobalt allergy and disappearance of symptoms after revision surgery with titanium-based endoprostheses
    Karin Almut Dietrich
    Department of Dermatology and Allergy, University of Munich, Germany
    J Dtsch Dermatol Ges 7:410-3. 2009
    ..The subsequent alleviation of symptoms underlined the relevance and usefulness of allergological diagnostics in selected cases of complicated arthroplasty...
  23. ncbi request reprint Patch test reactivity to a cobalt-chromium-molybdenum alloy and stainless steel in metal-allergic patients in correlation to the metal ion release
    Burkhard Summer
    Klinik und Poliklinik für Dermatologie und Allergologie der, Ludwig Maximilians Universitat Munchen, Frauenlobstr 9 11, D 80337 München, Germany
    Contact Dermatitis 57:35-9. 2007
    ..None of the controls reacted to the discs. Apart from nickel being a focus of allergological research, our results point to the possibly underestimated association of cobalt release and potential hyperreactivity to CoCrMo alloy...
  24. ncbi request reprint Contact allergy to propylene glycol and dodecyl gallate mimicking seborrheic dermatitis
    Alexander V Kuznetsov
    Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Contact Dermatitis 55:307-8. 2006
  25. ncbi request reprint Cross-sensitization between poppy seed and buckwheat in a food-allergic patient with poppy seed anaphylaxis
    Tilmann Oppel
    Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
    Int Arch Allergy Immunol 140:170-3. 2006
    ..Allergological workup revealed a poppy seed anaphylaxis and led to the identification of a novel cross-sensitization with buckwheat...
  26. ncbi request reprint [The tuberculid concept from the current viewpoint]
    O Braun-Falco
    Dermatologische Klinik und Poliklinik, Ludwig Maximilians Universitat, Munchen
    Hautarzt 46:383-7. 1995
    ..An increasing number of case reports on tuberculids, new immunological tests and molecular biology-based techniques for the detection of mycobacteria have shed new light on the tuberculid concept...
  27. ncbi request reprint Systemic contact dermatitis elicited by oral intake of Balsam of Peru
    Wolfgang Pfutzner
    Acta Derm Venereol 83:294-5. 2003
  28. ncbi request reprint Biomechanical and allergological characteristics of a biodegradable poly(D,L-lactic acid) coating for orthopaedic implants
    Hans Gollwitzer
    Klinik und Poliklinik für Orthopädie und Sportorthopädie, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munchen, Germany
    J Orthop Res 23:802-9. 2005
    ..PDLLA coating proved high mechanical stability on different orthopaedic implants and did not influence in vitro T-cell reactivity towards specific biomaterials...
  29. pmc Inhibition of lipopolysaccharide activation of Kupffer cells by transition metals
    Peter Thomas
    Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    J Surg Res 148:116-20. 2008
    ..Endotoxin intravenously administered to mice can have fatal consequences. Previous studies have shown that the transition metals Mn2+ and Cr3+ can be protective...
  30. ncbi request reprint Vitamin E co-treatment reduces Aroclor 1254-induced impairment of reproductive neuroendocrine function in Atlantic croaker
    Izhar A Khan
    Marine Science Institute, The University of Texas at Austin, 750 Channelview Drive, Port Aransas, TX 78373, USA
    Mar Environ Res 58:333-6. 2004
    ..The vitamin E co-treatments (1 and 10 mg/100 g BW/day) with PCB significantly reduced the effects of PCB on TPH activity and gonadal growth. These results suggest possible involvement of oxidative processes in PCB neurotoxicity...
  31. ncbi request reprint Controlling cell biomechanics in orthopaedic tissue engineering and repair
    Alicia J El Haj
    Institute of Science and Technology in Medicine, Keele University Medical School, University Hospital of North Staffordshire, Hartshill, Stoke on Trent ST4 7QB, UK
    Pathol Biol (Paris) 53:581-9. 2005
    ..The effects of these factors on successful bone tissue formation observed in increased matrix protein synthesis due to the optimisation of mechano-transduction pathways is discussed...