A Thies

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. doi request reprint Magnetic resonance imaging of melanoma metastases in a clinical relevant human melanoma xenograft scid mouse model
    Anka Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Cancer Lett 274:194-200. 2009
  2. pmc Low-dose mistletoe lectin-I reduces melanoma growth and spread in a scid mouse xenograft model
    A Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Br J Cancer 98:106-12. 2008
  3. pmc Clinically proven markers of metastasis predict metastatic spread of human melanoma cells engrafted in scid mice
    A Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg D 20246, Germany
    Br J Cancer 96:609-16. 2007
  4. ncbi request reprint Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: implications for diagnosis and pathophysiology of metastases
    Anka Thies
    Institut für Anatomie II Experimentelle Morphologie, Zentrum für Experimentelle Medizin, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Cancer Lett 248:68-80. 2007
  5. ncbi request reprint Influence of mistletoe lectins and cytokines induced by them on cell proliferation of human melanoma cells in vitro
    Anka Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II, Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Toxicology 207:105-16. 2005
  6. ncbi request reprint The developmentally regulated neural crest-associated glycotope HNK-1 predicts metastasis in cutaneous malignant melanoma
    Anka Thies
    Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Pathol 203:933-9. 2004
  7. ncbi request reprint Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma
    Anka Thies
    Institut fur Anatomie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Eur J Cancer 38:1708-16. 2002
  8. ncbi request reprint CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease
    Anka Thies
    Institute for Anatomy, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Clin Oncol 20:2530-6. 2002
  9. ncbi request reprint PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma
    A Thies
    Department of Anatomy, University Hospital Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Pathol 195:537-42. 2001
  10. ncbi request reprint Binding of mistletoe lectins to cutaneous malignant melanoma: implications for prognosis and therapy
    A Thies
    Institute for Anatomy, University of Witten Herdecke, Witten, Germany
    Anticancer Res 21:2883-7. 2001

Detail Information

Publications13

  1. doi request reprint Magnetic resonance imaging of melanoma metastases in a clinical relevant human melanoma xenograft scid mouse model
    Anka Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Cancer Lett 274:194-200. 2009
    ....
  2. pmc Low-dose mistletoe lectin-I reduces melanoma growth and spread in a scid mouse xenograft model
    A Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Br J Cancer 98:106-12. 2008
    ..01). Our results demonstrate that low-dose ML-I reduced melanoma growth and number of metastases in vivo, primarily due to immunomodulatory effects...
  3. pmc Clinically proven markers of metastasis predict metastatic spread of human melanoma cells engrafted in scid mice
    A Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg D 20246, Germany
    Br J Cancer 96:609-16. 2007
    ....
  4. ncbi request reprint Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: implications for diagnosis and pathophysiology of metastases
    Anka Thies
    Institut für Anatomie II Experimentelle Morphologie, Zentrum für Experimentelle Medizin, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Cancer Lett 248:68-80. 2007
    ..Both CAMs seem to be functionally involved in lymphatic and haematogenous spread, and are thus promising target molecules for immunotoxins...
  5. ncbi request reprint Influence of mistletoe lectins and cytokines induced by them on cell proliferation of human melanoma cells in vitro
    Anka Thies
    Zentrum für Experimentelle Medizin, Institut für Anatomie II, Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Toxicology 207:105-16. 2005
    ..The observation of an ultra-sensitivity of one cell line towards ML-I toxicity may serve as an explanation for the therapeutic success in anecdotal case reports and needs further investigations...
  6. ncbi request reprint The developmentally regulated neural crest-associated glycotope HNK-1 predicts metastasis in cutaneous malignant melanoma
    Anka Thies
    Institut für Anatomie II Experimentelle Morphologie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Pathol 203:933-9. 2004
    ..As HNK-1 is also transiently expressed during migration of melanocyte precursor cells derived from the neural crest, recapitulation of this transient expression might occur during metastatic spread of cutaneous malignant melanoma...
  7. ncbi request reprint Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma
    Anka Thies
    Institut fur Anatomie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Eur J Cancer 38:1708-16. 2002
    ..The functional role of L1 was further stressed by the fact that its expression was preserved in metastatic lesions...
  8. ncbi request reprint CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease
    Anka Thies
    Institute for Anatomy, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Clin Oncol 20:2530-6. 2002
    ..CEACAM1 downregulation has been demonstrated in colorectal and prostate carcinomas. This study sought to analyze whether its expression in malignant melanoma is associated with metastasis...
  9. ncbi request reprint PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma
    A Thies
    Department of Anatomy, University Hospital Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Pathol 195:537-42. 2001
    ....
  10. ncbi request reprint Binding of mistletoe lectins to cutaneous malignant melanoma: implications for prognosis and therapy
    A Thies
    Institute for Anatomy, University of Witten Herdecke, Witten, Germany
    Anticancer Res 21:2883-7. 2001
    ..Glycoconjugates, as detected by lectin histochemistry, have been implicated in metastasis formation in many neoplasias. However, no data concerning the three mistletoe lectins (MLs) and the spread of malignant melanoma have been published...
  11. pmc Lectin binding to cutaneous malignant melanoma: HPA is associated with metastasis formation
    A Thies
    Institute for Anatomy, University Hospital Hamburg Eppendorf, Martinistrasse 52, Hamburg, D 20246 Hamburg
    Br J Cancer 84:819-23. 2001
    ..Thus, HPA proved to be a useful and independent prognostic marker for the metastatic phenotype of melanoma...
  12. ncbi request reprint Anti-proliferative effect of peroxisome proliferator-activated receptor gamma agonists on human malignant melanoma cells in vitro
    Christian Freudlsperger
    Zentrum für Experimentelle Medizin, Institut für Anatomie II Experimentelle Morphologie, Hamburg, Germany
    Anticancer Drugs 17:325-32. 2006
    ..As an already approved class of drugs, glitazones have been found to significantly inhibit growth of human malignant melanoma cells in vitro and might be a promising tool for further therapeutic studies...
  13. ncbi request reprint The proteasome inhibitor bortezomib augments anti-proliferative effects of mistletoe lectin-I and the PPAR-gamma agonist rosiglitazone in human melanoma cells
    Christian Freudlsperger
    Institut für Anatomie II Experimentelle Morphologie, Universitätsklinikum Hamburg Eppendorf 20246 Hamburg, Germany
    Anticancer Res 27:207-13. 2007
    ....