Research Topics
| C TermeerSummaryAffiliation: University of Freiburg Country: Germany Publications
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Detail Information
Publications
Oligosaccharides of hyaluronan are potent activators of dendritic cellsC C Termeer
Department of Dermatology, University of Freiburg, Freiburg, Germany
J Immunol 165:1863-70. 2000..However, TNF-alpha is an essential mediator of sHA-induced DC maturation as shown by blocking studies with a soluble TNFR1. These findings suggest that during inflammation, interaction of DC with small HA fragments induce DC maturation...
Targeting dendritic cells with CD44 monoclonal antibodies selectively inhibits the proliferation of naive CD4+ T-helper cells by induction of FAS-independent T-cell apoptosisChristian Termeer
Department of Dermatology, University of Freiburg, Germany
Immunology 109:32-40. 2003..Taken together, we found that perturbation of distinct epitopes of CD44 on DC interfere with early Ca2+ signalling events during the activation of CD4+ T cells, resulting in T-cell apoptosis...- Hyaluronan--magic glue for the regulation of the immune response?Christian Termeer
Department of Dermatology, University of Freiburg, Hauptstrasse 7, D 79104 Freiburg, Germany
Trends Immunol 24:112-4. 2003 - Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4Christian Termeer
Department of Dermatology, University of Freiburg, Freiburg D 79104, Germany
J Exp Med 195:99-111. 2002..In conclusion, this is the first report that polysaccharide degradation products of the extracellular matrix produced during inflammation might serve as an endogenous ligand for the TLR-4 complex on DCs... - The role of CD44 during CD40 ligand-induced dendritic cell clustering and maturationC Termeer
Department of Dermatology, University of Freiburg, Germany
J Leukoc Biol 70:715-22. 2001..However, co-incubation with HA-degrading enzymes induced no changes in the CD154-mediated DC clustering and maturation... - CD44 is the principal mediator of hyaluronic-acid-induced melanoma cell proliferationT Ahrens
Department of Dermatology, University of Freiburg, Freiburg, Germany
J Invest Dermatol 116:93-101. 2001.... - Downregulation of platelet-activating factor responsiveness during maturation of human dendritic cellsS Dichmann
Department of Experimental and Clinical Dermatology, University of Freiburg, Germany
J Cell Physiol 185:394-400. 2000..Therefore, these findings point to a functional relevance of PAF in recruiting immature DCs, whereas MIP-3beta might regulate the migration of DCs at a later stage of maturation... - [Erythema annulare centrifugum Darier. Successful therapy with topical calcitriol and 311 nm-ultraviolet B narrow band phototherapy]J Reuter
Universitäts Hautklinik, Hauptstrasse 7, 79104 Freiburg
Hautarzt 58:146-8. 2007..The combination topical vitamin D3-analogue calcitriol and 311 nm ultraviolet B narrow band phototherapy was effective and can be regarded as a useful alternative to glucocorticosteroids for erythema annulare centrifugum... - Management of actinic cheilitis using diclofenac 3% gel: a report of six casesC Ulrich
Department of Dermatology, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
Br J Dermatol 156:43-6. 2007..Diclofenac 3% gel is used in the treatment of actinic keratosis (AK), but it has not been evaluated for the treatment of actinic cheilitis... - [Tacrolimus--a new therapeutic option for Hailey-Hailey-disease?]Juliane Reuter
Universitäts Hautklinik, Freiburg
J Dtsch Dermatol Ges 3:278-9. 2005..After four weeks of treatment, the pain and erosions were significantly ameliorated. The efficacy of topical tacrolimus in Hailey-Hailey disease may provide new insights into the pathogenesis of the disorder... - Early cytoskeletal rearrangement during dendritic cell maturation enhances synapse formation and Ca(2+) signaling in CD8(+) T cellsMarco Averbeck
Department of Dermatology, University of Leipzig, Leipzig, Germany
Eur J Immunol 34:2708-19. 2004..These data indicate that already very early after receiving a maturation stimulus, DC display enhanced cytoskeletal activity resulting in the rapid formation of immunological synapses and effective CD8(+) T cell stimulation... - Hyaluronan-oligosaccharide-induced transcription of metalloproteasesChristina Fieber
Forschungszentrum Karlsruhe, Institute of Toxicology and Genetics, and University of Karlsruhe, Institute of Genetics, PO Box 3640, 76021 Karlsruhe, Germany
J Cell Sci 117:359-67. 2004..Finally, we show that HA fragment-induced MMP-9 transcription is mediated via NF-kappa B. Our results suggest that the metastasis-associated HA degradation in tumours might promote invasion by inducing MMP expression... - Mature monocyte-derived dendritic cells respond more strongly to CCL19 than to CXCL12: consequences for directional migrationJens Y Humrich
Department of Dermatology, University Hospital of Erlangen, Germany
Immunology 117:238-47. 2006.... - Distinct effects of sphingosine-1-phosphate, lysophosphatidic acid and histamine in human and mouse dendritic cellsAndreas Renkl
Department of Dermatology, University of Ulm, Germany
Int J Mol Med 13:203-9. 2004..These findings suggest that mouse models might underestimate the complex regulative network between mast cells, platelets and DC... - Switch in syndecan-1 and syndecan-4 expression controls maturation associated dendritic cell motilityMarco Averbeck
Department of Dermatology, Venerology and Allergology, Leipzig University, Leipzig, Germany
Exp Dermatol 16:580-9. 2007....