Research Topics
| Vladimir B TeifSummaryAffiliation: University of Heidelberg Country: Germany Publications
|
Detail Information
Publications
Calculating transcription factor binding maps for chromatinVladimir B Teif
BioQuant and German Cancer Research Center DKFZ, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany
Brief Bioinform 13:187-201. 2012..Strategies are discussed that could further facilitate calculations to allow computing genome-wide TF binding maps...
Predicting nucleosome positions on the DNA: combining intrinsic sequence preferences and remodeler activitiesVladimir B Teif
Research Group Genome Organization and Function, Deutsches Krebsforschungszentrum and BIOQUANT, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Nucleic Acids Res 37:5641-55. 2009..Cell 132, p. 887] it was concluded that the redistribution of a nucleosome map to a new state is greatly facilitated if the remodeler complex translocates the nucleosome with a preferred directionality...
Predicting gene-regulation functions: lessons from temperate bacteriophagesVladimir B Teif
Research Group Genome Organization and Function, Deutsches Krebsforschungszentrum and BIOQUANT, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Biophys J 98:1247-56. 2010....
Condensed DNA: condensing the conceptsVladimir B Teif
BioQuant and German Cancer Research Center, Im Neuenheimer Feld 267, Heidelberg, Germany
Prog Biophys Mol Biol 105:208-22. 2011..We end up with an extended discussion of the role of DNA condensation in the context of gene regulation and mention potential applications of DNA condensation in gene therapy and biotechnology...
A lattice model for transcription factor access to nucleosomal DNAVladimir B Teif
BioQuant and German Cancer Research Center, Heidelberg, Germany
Biophys J 99:2597-607. 2010..These findings indicate that partial unwrapping of DNA from the histone octamer needs to be taken into account in quantitative models of gene regulation in chromatin...
Statistical-mechanical lattice models for protein-DNA binding in chromatinVladimir B Teif
Research Group Genome Organization and Function, Deutsches Krebsforschungszentrum and BIOQUANT, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
J Phys Condens Matter 22:414105. 2010..The results have a number of applications for quantitative models for the regulation of gene expression...
Nucleosome mediated crosstalk between transcription factors at eukaryotic enhancersVladimir B Teif
BioQuant and German Cancer Research Center, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany
Phys Biol 8:044001. 2011..In addition, the proposed model offers explanations for other distance-dependent effects at eukaryotic enhancers...
Genome-wide nucleosome positioning during embryonic stem cell developmentVladimir B Teif
Research Group Genome Organization and Function, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Nat Struct Mol Biol 19:1185-92. 2012..Our results reveal regulatory mechanisms of cell differentiation that involve nucleosome repositioning...
