A Tauch

Summary

Affiliation: University of Bielefeld
Country: Germany

Publications

  1. ncbi The surface (S)-layer gene cspB of Corynebacterium glutamicum is transcriptionally activated by a LuxR-type regulator and located on a 6 kb genomic island absent from the type strain ATCC 13032
    Nicole Hansmeier
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Microbiology 152:923-35. 2006
  2. ncbi The Corynebacterium glutamicum gene pmt encoding a glycosyltransferase related to eukaryotic protein-O-mannosyltransferases is essential for glycosylation of the resuscitation promoting factor (Rpf2) and other secreted proteins
    Martina Mahne
    Institut für Genomforschung, Centrum für Biotechnologie, Bielefeld, Germany
    FEMS Microbiol Lett 259:226-33. 2006
  3. pmc The alternative sigma factor SigB of Corynebacterium glutamicum modulates global gene expression during transition from exponential growth to stationary phase
    Christof Larisch
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, 33594 Bielefeld, Germany
    BMC Genomics 8:4. 2007
  4. pmc Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms
    Jan Baumbach
    International Computer Science Institute, Berkeley, CA 94704, USA
    BMC Syst Biol 3:8. 2009
  5. pmc The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacterium diphtheriae and Corynebacterium jeikeium deduced from the complete genome sequences
    Iris Brune
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstr, 25, D 33615 Bielefeld, Germany
    BMC Genomics 6:86. 2005
  6. pmc CoryneRegNet: an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks
    Jan Baumbach
    International NRW Graduate School in Bioinformatics and Genome Research, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    BMC Genomics 7:24. 2006
  7. pmc The DtxR protein acting as dual transcriptional regulator directs a global regulatory network involved in iron metabolism of Corynebacterium glutamicum
    Iris Brune
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    BMC Genomics 7:21. 2006
  8. pmc EMMA 2--a MAGE-compliant system for the collaborative analysis and integration of microarray data
    Michael Dondrup
    Computational Genomics, Center for Biotechnology, Bielefeld University, 33594 Bielefeld, Germany
    BMC Bioinformatics 10:50. 2009
  9. ncbi Plasmids in Corynebacterium glutamicum and their molecular classification by comparative genomics
    Andreas Tauch
    Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 104:27-40. 2003
  10. doi Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids
    Andreas Tauch
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 136:22-30. 2008

Collaborators

Detail Information

Publications63

  1. ncbi The surface (S)-layer gene cspB of Corynebacterium glutamicum is transcriptionally activated by a LuxR-type regulator and located on a 6 kb genomic island absent from the type strain ATCC 13032
    Nicole Hansmeier
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Microbiology 152:923-35. 2006
    ..Disruption of the cg2831 gene in C. glutamicum resulted in an almost complete loss of PS2 synthesis. These results suggested that Cg2831 is a transcriptional activator of cspB gene expression in C. glutamicum...
  2. ncbi The Corynebacterium glutamicum gene pmt encoding a glycosyltransferase related to eukaryotic protein-O-mannosyltransferases is essential for glycosylation of the resuscitation promoting factor (Rpf2) and other secreted proteins
    Martina Mahne
    Institut für Genomforschung, Centrum für Biotechnologie, Bielefeld, Germany
    FEMS Microbiol Lett 259:226-33. 2006
    ....
  3. pmc The alternative sigma factor SigB of Corynebacterium glutamicum modulates global gene expression during transition from exponential growth to stationary phase
    Christof Larisch
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, 33594 Bielefeld, Germany
    BMC Genomics 8:4. 2007
    ..glutamicum and is responsible for promoter recognition of house-keeping genes. The sigB gene codes for the non-essential sigma factor SigB that has a proposed role in stress reponse...
  4. pmc Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms
    Jan Baumbach
    International Computer Science Institute, Berkeley, CA 94704, USA
    BMC Syst Biol 3:8. 2009
    ..However, the prediction quality is limited by the low level of evolutionary conservation of the transcription factor binding sites, even within organisms of the same genus...
  5. pmc The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacterium diphtheriae and Corynebacterium jeikeium deduced from the complete genome sequences
    Iris Brune
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstr, 25, D 33615 Bielefeld, Germany
    BMC Genomics 6:86. 2005
    ..Here, we apply a combination of bioinformatic tools and a comparative genomic approach to identify and characterize a set of conserved DNA-binding transcriptional regulators in the four corynebacterial genomes...
  6. pmc CoryneRegNet: an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks
    Jan Baumbach
    International NRW Graduate School in Bioinformatics and Genome Research, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    BMC Genomics 7:24. 2006
    ..These large-scale reconstructions can be converted into in silico models of bacterial cells that allow a systematic analysis of network behavior in response to changing environmental conditions...
  7. pmc The DtxR protein acting as dual transcriptional regulator directs a global regulatory network involved in iron metabolism of Corynebacterium glutamicum
    Iris Brune
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    BMC Genomics 7:21. 2006
    ..Here, we apply a combination of transcriptomics, bioinformatics, in vitro assays, and comparative genomics to decipher the regulatory network of the iron-dependent transcriptional regulator DtxR of Corynebacterium glutamicum...
  8. pmc EMMA 2--a MAGE-compliant system for the collaborative analysis and integration of microarray data
    Michael Dondrup
    Computational Genomics, Center for Biotechnology, Bielefeld University, 33594 Bielefeld, Germany
    BMC Bioinformatics 10:50. 2009
    ..Integration of genomic annotation data and other sources of external knowledge using open standards is therefore a key requirement for future integrated analysis systems...
  9. ncbi Plasmids in Corynebacterium glutamicum and their molecular classification by comparative genomics
    Andreas Tauch
    Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 104:27-40. 2003
    ..glutamicum plasmid families...
  10. doi Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids
    Andreas Tauch
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 136:22-30. 2008
    ..A complete beta-oxidation pathway involved in the degradation of fatty acids is present in the genome. Evaluation of the genomic data indicated that lipophilism is the dominant feature involved in pathogenicity of C. kroppenstedtii...
  11. pmc Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora
    Andreas Tauch
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Bacteriol 187:4671-82. 2005
    ..The predicted virulence factors of C. jeikeium K411 are apparently involved in ensuring the availability of exogenous fatty acids by damaging the host tissue...
  12. ncbi Comparative genomics identified two conserved DNA modules in a corynebacterial plasmid family present in clinical isolates of the opportunistic human pathogen Corynebacterium jeikeium
    Andreas Tauch
    Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Plasmid 52:102-18. 2004
    ..jeikeium strains, which revealed 16S-23S rDNA spacer length polymorphisms and specific antibiotic susceptibility profiles, implying a wide dissemination of the plasmid in clinical isolates of C. jeikeium...
  13. pmc Rational design of a Corynebacterium glutamicum pantothenate production strain and its characterization by metabolic flux analysis and genome-wide transcriptional profiling
    Andrea T Hüser
    Lehrstuhl fur Genetik, Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Appl Environ Microbiol 71:3255-68. 2005
    ..Our strategy not only successfully improved pantothenate production by genetically modified C. glutamicum strains but also revealed new constraints in attaining high productivity...
  14. ncbi The 79,370-bp conjugative plasmid pB4 consists of an IncP-1beta backbone loaded with a chromate resistance transposon, the strA-strB streptomycin resistance gene pair, the oxacillinase gene bla(NPS-1), and a tripartite antibiotic efflux system of the resi
    A Tauch
    Zentrum für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, 33615, Bielefeld, Germany
    Mol Genet Genomics 268:570-84. 2003
    ..The global genetic organization of pB4 implies that its gene load might be disseminated between bacteria in different habitats by the combined action of the conjugation apparatus and the mobility of its component elements...
  15. ncbi The alanine racemase gene alr is an alternative to antibiotic resistance genes in cloning systems for industrial Corynebacterium glutamicum strains
    Andreas Tauch
    Degussa AG, Kantstrasse 2, D 33788 Halle Künsebeck, Germany
    J Biotechnol 99:79-91. 2002
    ..glutamicum strains. In an application example, the novel deltaalr host-alr(+) vector-system for C. glutamicum was used to overproduce the vitamin D-pantothenic acid...
  16. doi The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing
    Andreas Tauch
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 136:11-21. 2008
    ..The complete genome sequence of C. urealyticum revealed a detailed picture of the lifestyle of this opportunistic human pathogen...
  17. ncbi Strategy to sequence the genome of Corynebacterium glutamicum ATCC 13032: use of a cosmid and a bacterial artificial chromosome library
    Andreas Tauch
    Zentrum für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 95:25-38. 2002
    ..A total of 21 BACs represented linking clones between previously sequenced cosmid contigs and provided a valuable tool for completing the genome sequence of C. glutamicum...
  18. ncbi TetZ, a new tetracycline resistance determinant discovered in gram-positive bacteria, shows high homology to gram-negative regulated efflux systems
    A Tauch
    Degussa Hüls AG, Kantstrabetae 2, Halle Künsebeck, D 33790, Germany
    Plasmid 44:285-91. 2000
    ..This is the first time a repressor-regulated tet gene has been found in gram-positive bacteria. A new class of tetracycline resistance and repressor proteins, termed TetA(Z) and TetR(Z), is proposed...
  19. ncbi The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens
    A Tauch
    Lehrstuhl fur Genetik, Universitat Bielefeld, Germany
    Mol Gen Genet 263:1-11. 2000
    ....
  20. pmc The Zur regulon of Corynebacterium glutamicum ATCC 13032
    Jasmin Schröder
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, D 33615 Bielefeld, Germany
    BMC Genomics 11:12. 2010
    ....
  21. doi The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model
    Thomas A Kohl
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstrasse 27, D 33615 Bielefeld, Germany
    J Biotechnol 143:239-46. 2009
    ..glutamicum. This network model exhibited a hierarchical and modular structure and is characterized by the presence of master regulators in each functional module, with GlxR serving as the dominating regulatory hub...
  22. doi The GlxR regulon of the amino acid producer Corynebacterium glutamicum: in silico and in vitro detection of DNA binding sites of a global transcription regulator
    Thomas A Kohl
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 135:340-50. 2008
    ....
  23. pmc The IclR-type transcriptional repressor LtbR regulates the expression of leucine and tryptophan biosynthesis genes in the amino acid producer Corynebacterium glutamicum
    Iris Brune
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Bacteriol 189:2720-33. 2007
    ..glutamicum IB1486...
  24. ncbi The McbR repressor modulated by the effector substance S-adenosylhomocysteine controls directly the transcription of a regulon involved in sulphur metabolism of Corynebacterium glutamicum ATCC 13032
    Daniel A Rey
    Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, 33615 Bielefeld, Germany
    Mol Microbiol 56:871-87. 2005
    ..As the activity of McbR is modulated by S-adenosylhomocysteine, a major product of transmethylation reactions, the results point also to a novel regulatory mechanism in bacteria to control the biosynthesis of S-adenosylmethionine...
  25. ncbi Isoleucine uptake in Corynebacterium glutamicum ATCC 13032 is directed by the brnQ gene product
    A Tauch
    Lehrstuhl fur Genetik, Universitat Bielefeld, Postfach 100131, D 33501 Bielefeld, Germany
    Arch Microbiol 169:303-12. 1998
    ..3 nmol min-1 mg (dry mass)-1. Evidently, the brnQ gene encodes the only transport system in C. glutamicum directing isoleucine uptake...
  26. pmc The extracytoplasmic function-type sigma factor SigM of Corynebacterium glutamicum ATCC 13032 is involved in transcription of disulfide stress-related genes
    Diana Nakunst
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, 33501 Bielefeld, Germany
    J Bacteriol 189:4696-707. 2007
    ..A typical SigH-responsive promoter was mapped upstream of the sigM gene. The ECF sigma factor SigM is apparently part of a regulatory cascade, and its transcription is controlled by SigH under conditions of thiol-oxidative stress...
  27. doi Characterization of the LacI-type transcriptional repressor RbsR controlling ribose transport in Corynebacterium glutamicum ATCC 13032
    Svenja S Nentwich
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstrasse 27, 33615 Bielefeld, Germany
    Microbiology 155:150-64. 2009
    ....
  28. pmc Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion
    Eva Trost
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstrasse 27, D 33615 Bielefeld, Germany
    BMC Genomics 11:91. 2010
    ..For a better understanding of the physiology and lifestyle of this potential urogenital pathogen, the complete genome sequence of C. aurimucosum ATCC 700975 was determined...
  29. ncbi Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum
    Alice C McHardy
    Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33515 Bielefeld, Germany
    J Biotechnol 104:229-40. 2003
    ..The theoretical and experimental data we present should further provide a solid platform for ongoing research and understanding of the network of aminotransferases which participate in amino acid biosynthesis in C. glutamicum...
  30. ncbi The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS6100
    Andreas Tauch
    Degussa AG, Kantstrasse 2, D 33790 Halle Künsebeck, Germany
    Plasmid 48:117-29. 2002
    ..glutamicum. These data suggest a central role of IS6100 in the evolutionary history of pTET3 by mediating the cointegrative assembly of resistance gene-carrying DNA segments...
  31. ncbi Insights into the genetic organization of the Corynebacterium diphtheriae erythromycin resistance plasmid pNG2 deduced from its complete nucleotide sequence
    Andreas Tauch
    Zentrum für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Plasmid 49:63-74. 2003
    ..The detailed annotation of the entire pNG2 sequence provided genetic information regarding its molecular evolution and its role in dissemination of antibiotic resistance genes by horizontal gene transfer...
  32. doi Genetic makeup of the Corynebacterium glutamicum LexA regulon deduced from comparative transcriptomics and in vitro DNA band shift assays
    Nina Jochmann
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstrasse 27, D 33615 Bielefeld, Germany
    Microbiology 155:1459-77. 2009
    ..One of the four LexA binding sites detected in the intergenic region is involved in regulating divS-nrdR transcription, whereas the other sites are apparently used for negative autoregulation of lexA expression...
  33. ncbi A Corynebacterium glutamicum mutant with a defined deletion within the rplK gene is impaired in (p)ppGpp accumulation upon amino acid starvation
    L Wehmeier
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, D 33501 Bielefeld, Germany
    Microbiology 147:691-700. 2001
    ..Evidently, the C. glutamicum rplK gene is required for (p)ppGpp accumulation upon nutritional starvation...
  34. ncbi Development of a Corynebacterium glutamicum DNA microarray and validation by genome-wide expression profiling during growth with propionate as carbon source
    Andrea T Hüser
    Lehrstuhl fur Genetik, Universitat Bielefeld, Universitatsstrasse 25, Bielefeld D 33615, Germany
    J Biotechnol 106:269-86. 2003
    ..Differential expression of these genes was confirmed by real-time reverse transcription (RT) PCR assays...
  35. doi Taxonomic composition and gene content of a methane-producing microbial community isolated from a biogas reactor
    Lutz Krause
    Centrum für Biotechnologie CeBiTec, Universitat Bielefeld, D 33594 Bielefeld, Germany
    J Biotechnol 136:91-101. 2008
    ..Finally, the results unveiled that most of the organisms constituting the sample are still unexplored...
  36. doi Triple transcriptional control of the resuscitation promoting factor 2 (rpf2) gene of Corynebacterium glutamicum by the regulators of acetate metabolism RamA and RamB and the cAMP-dependent regulator GlxR
    Britta Jungwirth
    Centrum für Biotechnologie, Institut für Genomforschung und Systembiologie, Universitat Bielefeld, Bielefeld, Germany
    FEMS Microbiol Lett 281:190-7. 2008
    ..glutamicum strain overexpressing glxR. The deduced network of regulatory interactions provided insights into the complex regulation pattern of rpf2 expression in C. glutamicum...
  37. ncbi The transcriptional regulator SsuR activates expression of the Corynebacterium glutamicum sulphonate utilization genes in the absence of sulphate
    Daniel J Koch
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, 33615 Bielefeld, Germany
    Mol Microbiol 58:480-94. 2005
    ..Therefore, the regulatory protein SsuR activates the expression of the ssu and seu genes in C. glutamicum in the absence of the preferred sulphur source sulphate...
  38. ncbi The complete nucleotide sequence and environmental distribution of the cryptic, conjugative, broad-host-range plasmid pIPO2 isolated from bacteria of the wheat rhizosphere
    Andreas Tauch
    Zentrum für Genomforschung, Universitat Bielefeld, D 33615 Bielefeld, Germany
    Microbiology 148:1637-53. 2002
    ..These data add to the growing evidence that plasmids carry advantageous genes with as yet undefined functions in plant-associated communities...
  39. doi The LacI/GalR family transcriptional regulator UriR negatively controls uridine utilization of Corynebacterium glutamicum by binding to catabolite-responsive element (cre)-like sequences
    Karina Brinkrolf
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Bielefeld, Germany
    Microbiology 154:1068-81. 2008
    ..glutamicum KB1547 with that of the wild-type strain revealed that UriR is a pathway-specific repressor of genes involved in uridine utilization in C. glutamicum...
  40. ncbi The cytosolic, cell surface and extracellular proteomes of the biotechnologically important soil bacterium Corynebacterium efficiens YS-314 in comparison to those of Corynebacterium glutamicum ATCC 13032
    Nicole Hansmeier
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Proteomics 6:233-50. 2006
    ..The high abundance of molecular chaperones and amino acid biosynthesis enzymes in C. efficiens points to environmental adaptations of this recently discovered amino acid-producing bacterium...
  41. ncbi The glycosylated cell surface protein Rpf2, containing a resuscitation-promoting factor motif, is involved in intercellular communication of Corynebacterium glutamicum
    Michael Hartmann
    Lehrstuhl fur Genetik, Universitat Bielefeld, Universitatsstrasse 25, Bielefeld, Germany
    Arch Microbiol 182:299-312. 2004
    ..In contrast, the lag phase of the C. glutamicum rpf double mutant was not affected upon addition of these culture supernatants...
  42. ncbi Classification of hyper-variable Corynebacterium glutamicum surface-layer proteins by sequence analyses and atomic force microscopy
    Nicole Hansmeier
    Lehrstuhl fur Genetik, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 112:177-93. 2004
    ..2 to 17.4 nm), which correlates with the sequence similarity-based classification. It could be demonstrated that differences in the primary structure of the S-layer proteins were reflected by the S-layer morphology...
  43. pmc The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate:sugar phosphotransferase system (PTS) in Corynebacterium glutamicum
    Lars Gaigalat
    Institut für Genomforschung, Universitat Bielefeld, D 33594 Bielefeld, Germany
    BMC Mol Biol 8:104. 2007
    ....
  44. ncbi Efficient electrotransformation of corynebacterium diphtheriae with a mini-replicon derived from the Corynebacterium glutamicum plasmid pGA1
    Andreas Tauch
    Zentrum für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    Curr Microbiol 45:362-7. 2002
    ..diphtheriae. Thus, the ability to apply the standard methods of C. glutamicum recombinant DNA technology will greatly facilitate the functional analysis of the recently completed C. diphtheriae genome sequence...
  45. ncbi Identification and characterization of the last two unknown genes, dapC and dapF, in the succinylase branch of the L-lysine biosynthesis of Corynebacterium glutamicum
    Michael Hartmann
    Lehrstuhl fur Genetik, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 104:199-211. 2003
    ..Overexpression of the dapF or the dapC gene in an industrial C. glutamicum strain resulted in an increased L-lysine production, indicating that both genes might be relevant targets for the development of improved production strains...
  46. ncbi Under the influence of the active deodorant ingredient 4-hydroxy-3-methoxybenzyl alcohol, the skin bacterium Corynebacterium jeikeium moderately responds with differential gene expression
    Iris Brune
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 127:21-33. 2006
    ..Differential expression of relevant genes was validated by real-time reverse transcription PCR assays...
  47. ncbi The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins
    Jorn Kalinowski
    Institut für Genomforschung, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 104:5-25. 2003
    ..As an example for biotechnological application the complete genome sequence was used to reconstruct the metabolic flow of carbon into a number of industrially important products derived from the amino acid L-aspartate...
  48. pmc Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway
    Sascha Mormann
    Institut für Genomforschung, Universitat Bielefeld, D 33594 Bielefeld, Germany
    BMC Genomics 7:205. 2006
    ..An efficient transposon mutagenesis system for the completely sequenced type strain ATCC 13032 would significantly advance functional genome analysis in this bacterium...
  49. doi Identification of McbR as transcription regulator of aecD and genes involved in methionine and cysteine biosynthesis in Corynebacterium jeikeium K411
    Iris Brune
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstraße 27, D 33615 Bielefeld, Germany
    J Biotechnol 151:22-9. 2011
    ..The McbR protein from C. jeikeium K411 directly regulates genes involved in methionine uptake and biosynthesis, in cysteine biosynthesis and sulfate reduction, and in the biosynthesis of amino acids belonging to the aspartate family...
  50. doi The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technology
    Andreas Schluter
    Lehrstuhl fur Genetik, Universitat Bielefeld, D 33594 Bielefeld, Germany
    J Biotechnol 136:77-90. 2008
    ..Metagenome sequence data from a biogas-producing microbial community residing in a fermenter of a biogas plant provide the basis for a rational approach to improve the biotechnological process of biogas production...
  51. doi Molecular basis of human body odour formation: insights deduced from corynebacterial genome sequences
    H Barzantny
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstraße 27, D 33615 Bielefeld, Germany
    Int J Cosmet Sci 34:2-11. 2012
    ..We particularly focused on the metabolic abilities of the lipophilic axillary isolate Corynebacterium jeikeium K411...
  52. ncbi Transcriptional regulation of catabolic pathways for aromatic compounds in Corynebacterium glutamicum
    K Brinkrolf
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Bielefeld, Germany
    Genet Mol Res 5:773-89. 2006
    ..glutamicum...
  53. ncbi Mapping and comprehensive analysis of the extracellular and cell surface proteome of the human pathogen Corynebacterium diphtheriae
    Nicole Hansmeier
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Universitätsstrasse, Bielefeld, Germany
    Proteomics 6:2465-76. 2006
    ..diphtheriae C7s(-)tox-...
  54. ncbi The transcriptional regulatory network of the amino acid producer Corynebacterium glutamicum
    Karina Brinkrolf
    Institut für Genomforschung, Centrum für Biotechnologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 129:191-211. 2007
    ..A graphical reconstruction revealed first insights into the functional modularity, the hierarchical architecture and the topological design principles of the transcriptional regulatory network of C. glutamicum...
  55. ncbi Tools for genetic engineering in the amino acid-producing bacterium Corynebacterium glutamicum
    Oliver Kirchner
    Lehrstuhl für Gentechnologie Mikrobiologie, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 104:287-99. 2003
    ..This repertoire of C. glutamicum methodology provides an experimental basis for efficient genetic analyses of the recently completed genome sequence...
  56. ncbi A comprehensive proteome map of the lipid-requiring nosocomial pathogen Corynebacterium jeikeium K411
    Nicole Hansmeier
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Bielefeld, Germany
    Proteomics 7:1076-96. 2007
    ....
  57. doi The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis
    Frank Jörg Vorhölter
    Universitat Bielefeld, Biologie VI Genetik, Universitatsstr 25, D 33615 Bielefeld, Germany
    J Biotechnol 134:33-45. 2008
    ..The updated genome annotation data allowed reconsidering and refining the mechanistic model for xanthan biosynthesis...
  58. doi The transcriptional regulatory repertoire of Corynebacterium glutamicum: reconstruction of the network controlling pathways involved in lysine and glutamate production
    Karina Brinkrolf
    Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universitat Bielefeld, Universitätsstrasse 27, D 33615 Bielefeld, Germany
    J Biotechnol 149:173-82. 2010
    ..glutamicum from the perspective of systems biology and may provide the basis for computational modeling of the respective biotechnologically important metabolic pathways...
  59. ncbi CoryneRegNet 3.0--an interactive systems biology platform for the analysis of gene regulatory networks in corynebacteria and Escherichia coli
    Jan Baumbach
    Algorithms and Statistics for Systems Biology Group, Genominformatik, Technische Fakultat, Universitat Bielefeld, Universitatsstrasse 25, D 33615 Bielefeld, Germany
    J Biotechnol 129:279-89. 2007
    ..coli and Corynebacterium glutamicum. CoryneRegNet is available at the following URL: http://www.cebitec.uni-bielefeld.de/groups/gi/software/coryneregnet/...
  60. ncbi Expression of alr gene from Corynebacterium glutamicum ATCC 13032 in Escherichia coli and molecular characterization of the recombinant alanine racemase
    Tadao Oikawa
    Department of Biotechnology, Faculty of Engineering, Kansai University, 3 3 35 Yamate cho, Suita, Osaka Fu 564 8680, Japan
    J Biotechnol 125:503-12. 2006
    ..The high substrate specificity of the Alr from C. glutamicum ATCC 13032 is expected to be a biocatalyst for d-alanine production from the l-counter part...
  61. pmc Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum
    Marco Ventura
    Department of Genetics, Biology of Microorganisms, Anthropology and Evolution, University of Parma, Parco Area delle Scienze 11A, 43100 Parma, Italy
    Microbiol Mol Biol Rev 71:495-548. 2007
    ..This review provides an account of the recent explosion of actinobacterial genomics data and an attempt to place this in a biological and evolutionary context...
  62. pmc Heat shock proteome analysis of wild-type Corynebacterium glutamicum ATCC 13032 and a spontaneous mutant lacking GroEL1, a dispensable chaperone
    Carlos Barreiro
    Institute of Biotechnology of León, INBIOTEC, Parque Cientifico de Leon, Av Real, 1, 24006 Leon, Spain
    J Bacteriol 187:884-9. 2005
    ..The GroEL1 chaperone is, therefore, dispensable in C. glutamicum. On the other hand, GroEL2 appears to be essential for growth. Based on these results, the role of the duplicate groEL1 and groEL2 genes is analyzed...
  63. ncbi ef1097 and ypkK encode enterococcin V583 and corynicin JK, members of a new family of antimicrobial proteins (bacteriocins) with modular structure from Gram-positive bacteria
    Pearl M Swe
    Department of Microbiology and Immunology, Otago School of Medical Sciences, The University of Otago, PO Box 56, Dunedin, New Zealand
    Microbiology 153:3218-27. 2007
    ..jeikeium. Finally, we determined that the proteins kill sensitive bacteria without lysis, a feature that distinguishes them from known murolytic proteins...