Research Topics
Species | A SzegediSummaryAffiliation: University of Mainz Country: Germany Publications
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Detail Information
Publications
Addition of low-dose fluvoxamine to low-dose clozapine monotherapy in schizophrenia: drug monitoring and tolerability data from a prospective clinical trialA Szegedi
Department of Psychiatry, University of Mainz, Germany
Pharmacopsychiatry 32:148-53. 1999..Further studies have to find out if the combined treatment could be advantageous to clozapine monotherapy...- Carbohydrate-deficient transferrin (CDT) and HDL cholesterol (HDL) are highly correlated in male alcohol dependent patientsA Szegedi
Department of Psychiatry, University of Mainz, Germany
Alcohol Clin Exp Res 24:497-500. 2000.... - Early improvement under mirtazapine and paroxetine predicts later stable response and remission with high sensitivity in patients with major depressionArmin Szegedi
Department of Psychiatry, University of Mainz, Mainz, Germany
J Clin Psychiatry 64:413-20. 2003..We aimed to test whether early improvement under antidepressant treatment is a clinically useful predictor of later stable response and remission... - Cue exposure in alcohol dependent patients: preliminary evidence for different types of cue reactivityA Szegedi
Department of Psychiatry, University of Mainz, Federal Republic of Germany
J Neural Transm 107:721-30. 2000..Different types of cue reactivity might be important for treatment strategies involving repeated cue exposure or so-called anti-craving drugs... - Mirtazapine compared with paroxetine in major depressionO Benkert
Psychiatrische Klinik, Universitat Mainz, Germany
J Clin Psychiatry 61:656-63. 2000..The aim was to compare the efficacy and tolerability of mirtazapine with those of paroxetine... - Sex differences in allelic frequencies of the 5-HT2C Cys23Ser polymorphism in psychiatric patients and healthy volunteers: findings from an association studyC Fehr
Department of Psychiatry, University of Mainz, Germany
Psychiatr Genet 10:59-65. 2000..0178). The potential mechanisms of the observed gender difference in allele frequencies, including transmission ratio distortion, are discussed... - Serotonergic polymorphisms in patients suffering from alcoholism, anxiety disorders and narcolepsyC Fehr
Department of Psychiatry, University of Mainz, Germany
Prog Neuropsychopharmacol Biol Psychiatry 25:965-82. 2001..4. There was no association between the 5-HT2A receptor polymorphism (T102C), the intron 7 TPH (A218C) polymorphisms and alcohol dependence, panic disorder, generalized anxiety disorder and narcolepsy in our subsets of German patients... - No association between the dopamine d2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteriaI Anghelescu
Department of Psychiatry, University of Mainz, Untere Zahlbacher Str 8, 55131 Mainz, Germany
Alcohol Clin Exp Res 25:805-9. 2001..The presence of the A1 allele of the dopamine D2 receptor TaqI restriction fragment length polymorphism has been reported to be associated with an earlier age of onset of alcohol dependence as a marker for severity... - GRIN1 locus may modify the susceptibility to seizures during alcohol withdrawalD Rujescu
Department of Psychiatry, University of Munich, Munich, Germany
Am J Med Genet B Neuropsychiatr Genet 133:85-7. 2005..These findings support the hypothesis that the GRIN1 locus may modify the susceptibility to seizures during alcohol withdrawal. This novel finding warrants replication... - Reliability and validity of the German version of the European Addiction Severity Index (EuropASI)A Scheurich
Department of Psychiatry, University of Mainz, Germany
J Stud Alcohol 61:916-9. 2000..The ASI is a frequently used clinical and research instrument that measures problem severity among people with substance dependence... - Association study of suicidal behavior and affective disorders with a genetic polymorphism in ABCG1, a positional candidate on chromosome 21q22.3D Rujescu
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Neuropsychobiology 42:22-5. 2000..Furthermore, we found no association with suicidal behavior. These findings do not support the hypothesis that ABCG1 is a susceptibility gene for affective disorders or suicidal behavior... - Vitamin B12 and hepatic enzyme serum levels correlate in male alcohol-dependent patientsH Himmerich
Department of Psychiatry, University of Mainz, Untere Zahlbacherstr. 8, D-55131 Mainz, Germany
Alcohol Alcohol 36:26-8. 2001..47; glutamate dehydrogenase: r(S) = 0.43; all P: < 0.001). Therefore, for a proper interpretation of vitamin B12 levels, it may be clinically relevant to take markers of hepatocellular damage into account... - The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depressionA Szegedi
Department of Psychiatry, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Pharmacogenomics J 5:49-53. 2005..Time course of response and antidepressant efficacy of mirtazapine, but not paroxetine, seem to be influenced in a clinically relevant manner by this allelic variation within the COMT gene... - Reliability and validity of the form 90 interviewA Scheurich
Department of Psychiatry, University of Mainz, Mainz, Germany
Eur Addict Res 11:50-6. 2005..Alcohol consumption is a central variable in substance abuse research and treatment. The study reports the psychometric characteristics of the German version of the Form 90 interview for the assessment of recent alcohol consumption... - The primary care evaluation of mental disorders (PRIME-MD), German version: a comparison with the CIDIB Loerch
Department of Psychiatry, University of Mainz, Untere Zahlbacher Str 8, 55131, Mainz, Germany
J Psychiatr Res 34:211-20. 2000.... - Association of a MAOA gene variant with generalized anxiety disorder, but not with panic disorder or major depressionA Tadic
Department of Psychiatry and Psychotherapy, University of Mainz, Mainz, Germany
Am J Med Genet B Neuropsychiatr Genet 117:1-6. 2003..However, the results are in line with previous data suggesting an association between the MAOA locus and regulation of complex human behavior... - Depressive factors and their relationships with other symptom domains in schizophrenia, schizoaffective disorder, and psychotic depressionM J Muller
Department of Psychiatry, University of Mainz, Germany
Schizophr Bull 27:19-28. 2001..A more differentiated assessment, analysis, and treatment of depressive symptoms is therefore recommended for patients with combined depressive and psychotic symptoms... - Moderate and severe depression. Gradations for the Montgomery-Asberg Depression Rating ScaleM J Muller
Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, D 55131, Mainz, Germany
J Affect Disord 60:137-40. 2000..Despite its importance, no distinction between moderate and severe depression using the Montgomery-Asberg Depression Rating Scale (MADRS) based on a direct comparison with the Hamilton Depression Rating Scale (HAMD-17) is available... - Neuropsychological status of alcohol-dependent patients: increased performance through goal-setting instructionsA Scheurich
Department of Psychiatry, University of Mainz, Mainz, Psychiatric Hospital Eichberg, Eltville, Germany
Alcohol Alcohol 39:119-25. 2004..The effects of goal-setting instructions on neuropsychological performance of alcohol-dependent patients and control subjects were assessed... - An overview of the clinical efficacy of mirtazapineO Benkert
Johannes Gutenberg University Mainz, Mainz, Germany
Hum Psychopharmacol 17:S23-6. 2002..The negative predictive value approached maximum values as early as week 2 with mirtazapine and week 3 with paroxetine. This suggests that the predictability of the response to treatment is better with mirtazapine than with paroxetine... - The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsyC Fehr
Department of Psychiatry, University of Mainz, Untere Zahlbacher Str 8, D 55101, Mainz, Germany
Psychiatry Res 97:1-10. 2000.... 
Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St John's wort): randomised controlled double blind non-inferiority trial versus paroxetineA Szegedi
, Campus Benjamin Franklin, Department of Psychiatry and Psychotherapy, Eschenallee 3, 14050 Berlin, Germany
BMJ 330:503. 2005..060 events per day of exposure for hypericum and paroxetine, respectively. CONCLUSIONS: In the treatment of moderate to severe major depression, hypericum extract WS 5570 is at least as effective as paroxetine and is better tolerated...- Comparison of Hypericum extract WS 5570 and paroxetine in ongoing treatment after recovery from an episode of moderate to severe depression: results from a randomized multicenter studyI G Anghelescu
Department of Psychiatry and Psychotherapy, , Campus Benjamin Franklin, Berlin, Germany
Pharmacopsychiatry 39:213-9. 2006.... - [Combination treatment with SSRI and cognitive behavior therapy for relapse prevention of alcohol-dependent men. Results of a randomized, controlled multicenter therapeutic study]M Hautzinger
Psychologisches Institut, Eberhard Karls Universitat Tubingen
Nervenarzt 76:295-307. 2005.... - No association of alcohol dependence with a NMDA-receptor 2B gene variantG Schumann
Mol Psychiatry 8:11-2. 2003 - Predicting stable treatment response in patients with major depression treated with hypericum extract WS 5570/5572M Kieser
Dr Willmar Schwabe Pharmaceuticals, P O Box 410925, 76209 Karlsruhe, Germany
Pharmacopsychiatry 38:194-200. 2005.... - Significant correlation between the CD63 assay and the histamine release assay in chronic urticariaA Szegedi
Department of Dermatology, Medical and Health Science Centre, University of Debrecen, 98 Nagyerdei Str, Debrecen 4012, Hungary
Br J Dermatol 155:67-75. 2006..The diagnosis of autoimmune chronic urticaria (ACU) is difficult; the autologous serum skin test (ASST) seems to be a useful screening test, but reliable, additional confirmatory methods are needed...