Pavel Strnad

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. pmc Oblique bile duct predisposes to the recurrence of bile duct stones
    Pavel Strnad
    Department of Internal Medicine I, University Medical Centre Ulm, Ulm, Germany
    PLoS ONE 8:e54601. 2013
  2. doi request reprint CHOP-mediated hepcidin suppression modulates hepatic iron load
    Katrin Mueller
    Department of Internal Medicine I, University Hospital Ulm, Germany
    J Pathol 231:532-42. 2013
  3. ncbi request reprint High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8
    Ozlem Kucukoglu
    Department of Internal Medicine I, Center for Internal Medicine, University Medical Center Ulm, Ulm, Germany
    Hepatology 60:169-78. 2014
  4. pmc Hepcidin is an antibacterial, stress-inducible peptide of the biliary system
    Pavel Strnad
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    PLoS ONE 6:e16454. 2011
  5. doi request reprint Diagnosis of hereditary hemochromatosis in the era of genetic testing
    Christiane Trieß
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    Dig Dis Sci 57:2988-94. 2012
  6. pmc Keratin 8 variants are infrequent in patients with alcohol-related liver cirrhosis and do not associate with development of hepatocellular carcinoma
    Valentyn Usachov
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    BMC Gastroenterol 12:147. 2012
  7. doi request reprint Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection
    Peggy Schwarz
    Department of Internal Medicine I, Gastroenterology, University Hospital Ulm, Ulm, Germany
    Gut 61:193-201. 2012
  8. doi request reprint Keratins: markers and modulators of liver disease
    Pavel Strnad
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    Curr Opin Gastroenterol 28:209-16. 2012
  9. pmc Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis
    Mariia Lunova
    Department of Internal Medicine I, University Medical Center Ulm, Ulm, Germany
    PLoS ONE 7:e39972. 2012
  10. doi request reprint A novel method of forceps biopsy improves the diagnosis of proximal biliary malignancies
    Hasan Kulaksiz
    Department of Internal Medicine I, Center for Internal Medicine, University Medical Center Ulm, Ulm, Germany
    Dig Dis Sci 56:596-601. 2011

Collaborators

Detail Information

Publications13

  1. pmc Oblique bile duct predisposes to the recurrence of bile duct stones
    Pavel Strnad
    Department of Internal Medicine I, University Medical Centre Ulm, Ulm, Germany
    PLoS ONE 8:e54601. 2013
    ..In our study, we assessed the importance of an altered bile duct course for stone formation...
  2. doi request reprint CHOP-mediated hepcidin suppression modulates hepatic iron load
    Katrin Mueller
    Department of Internal Medicine I, University Hospital Ulm, Germany
    J Pathol 231:532-42. 2013
    ..The differences in iron metabolism between the two widely used fibrosis models likely reflect the differential regulation of hepcidin expression in human liver disease...
  3. ncbi request reprint High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8
    Ozlem Kucukoglu
    Department of Internal Medicine I, Center for Internal Medicine, University Medical Center Ulm, Ulm, Germany
    Hepatology 60:169-78. 2014
    ..Conclusion: Our data demonstrate that HF diet triggers aggregate formation and development of liver injury in susceptible individuals through misfolding and crosslinking of excess K8. (Hepatology 2014;60:169-178). ..
  4. pmc Hepcidin is an antibacterial, stress-inducible peptide of the biliary system
    Pavel Strnad
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    PLoS ONE 6:e16454. 2011
    ..While the role of hepcidin in biliary system is unknown, a recent study demonstrated that conditional gp130-knockout mice display diminished hepcidin levels and increased rate of biliary infections...
  5. doi request reprint Diagnosis of hereditary hemochromatosis in the era of genetic testing
    Christiane Trieß
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    Dig Dis Sci 57:2988-94. 2012
    ..Homozygous C282Y mutation in HFE gene is responsible for the majority of hereditary hemochromatosis cases. Since 1996 this mutation can be identified by a simple genetic test...
  6. pmc Keratin 8 variants are infrequent in patients with alcohol-related liver cirrhosis and do not associate with development of hepatocellular carcinoma
    Valentyn Usachov
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    BMC Gastroenterol 12:147. 2012
    ..The importance of K8/K18 in alcoholic liver disease as well as in established cirrhosis remains unknown...
  7. doi request reprint Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection
    Peggy Schwarz
    Department of Internal Medicine I, Gastroenterology, University Hospital Ulm, Ulm, Germany
    Gut 61:193-201. 2012
    ..Given that hepcidin was shown to be expressed in a variety of extrahepatic tissues and that stomach plays a role in iron absorption and in defence against infections, this study analysed the importance of hepcidin in the stomach...
  8. doi request reprint Keratins: markers and modulators of liver disease
    Pavel Strnad
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    Curr Opin Gastroenterol 28:209-16. 2012
    ..Keratins emerged as important tissue-protecting genes and keratin variants cause/predispose to development of more than 50 human disorders. Our review focuses on the importance of keratins in context of liver disease...
  9. pmc Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis
    Mariia Lunova
    Department of Internal Medicine I, University Medical Center Ulm, Ulm, Germany
    PLoS ONE 7:e39972. 2012
    ..Increased Hsp72 levels were implicated in protection from acute pancreatitis; a hypothesis which was not tested in a transgenic mouse model yet...
  10. doi request reprint A novel method of forceps biopsy improves the diagnosis of proximal biliary malignancies
    Hasan Kulaksiz
    Department of Internal Medicine I, Center for Internal Medicine, University Medical Center Ulm, Ulm, Germany
    Dig Dis Sci 56:596-601. 2011
    ..To improve the tumor detection rate, we developed a new method of forceps biopsy and compared it prospectively with endoscopic transpapillary brush cytology...
  11. doi request reprint Broad spectrum of hepatocyte inclusions in humans, animals, and experimental models
    Pavel Strnad
    Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany
    Compr Physiol 3:1393-436. 2013
    ..This is why hepatic aggregates represent a valuable tool to study the aggregation process in general and to improve our understanding of inclusions found in multiple human disorders...
  12. pmc Non-coding keratin variants associate with liver fibrosis progression in patients with hemochromatosis
    Pavel Strnad
    Department of Internal Medicine I, University Medical Center Ulm, Ulm, Germany
    PLoS ONE 7:e32669. 2012
    ..Given the association of K8/K18 variants with end-stage liver disease and progression in several chronic liver disorders, we studied the importance of keratin variants in patients with hemochromatosis...
  13. ncbi request reprint Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation
    Yoshiaki Sunami
    Institute of Physiological Chemistry, University of Ulm, Ulm, Germany
    Hepatology 56:1117-28. 2012
    ..The elimination of macrophages by clodronate-liposomes attenuated NF-κB-induced liver fibrosis in a liver-injury-independent manner...