Research Topics
Species | Sebastian StriethSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
[Piercing complications in the facial area]S Strieth
Klinik fur Hals, Nasen, Ohrenheilkunde, Klinikum Grosshadern und Innenstadt, LMU Munchen
MMW Fortschr Med 148:41-3. 2006..Through specific advice, early detection and treatment of complications, serious health damage to the wearer of piercing jewelry can be avoided...
Paclitaxel encapsulated in cationic liposomes increases tumor microvessel leakiness and improves therapeutic efficacy in combination with CisplatinSebastian Strieth
Department of Otorhinolaryngology, Campus Grosshadern, University of Munich, Munich, Germany
Clin Cancer Res 14:4603-11. 2008....
Biocompatibility of porous polyethylene implants tissue-engineered by extracellular matrix and VEGFSebastian Strieth
Walter Brendel Center for Experimental Medicine WBex, University of Munich LMU, Marchioninistr 27, Munich 81377, Germany
J Biomed Mater Res A 93:1566-73. 2010..Therefore, novel tissue- engineered constructs of PPE implants providing ECM and VEGF in high local concentrations can increase biocompatibility especially under unfavorable conditions for implantation...
Static magnetic fields induce blood flow decrease and platelet adherence in tumor microvesselsSebastian Strieth
Department of Otorhinolaryngology, Universityof Munich LMU, Marchioninistr 15, Munich 81377 Germany
Cancer Biol Ther 7:814-9. 2008..These reversible changes may have implications for functional measurements of tumor microcirculation by MRI and new therapeutic strategies using strong SMFs...
Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomesSebastian Strieth
Institute for Surgical Research, University of Munich LMU, Germany
Int J Cancer 122:452-60. 2008..Significantly disbalancing the coagulation system within tumors by targeted induction of microthromboses within the tumor microcirculation appears to be an important mechanism of EndoTAG-1 therapy...
Antiangiogenic combination tumor therapy blocking alpha(v)-integrins and VEGF-receptor-2 increases therapeutic effects in vivoSebastian Strieth
Institute for Surgical Research, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
Int J Cancer 119:423-31. 2006....
A new animal model to assess angiogenesis and endocrine function of parathyroid heterografts in vivoSebastian Strieth
Institute for Surgical Research, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
Transplantation 79:392-400. 2005..We provide a new animal model allowing simultaneous and repetitive in vivo assessment of angiogenesis and endocrine function of parathyroid transplants...
Neovascular targeting chemotherapy: encapsulation of paclitaxel in cationic liposomes impairs functional tumor microvasculatureSebastian Strieth
Institute for Surgical Research, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
Int J Cancer 110:117-24. 2004..Remarkable microcirculatory changes indicate that encapsulation of paclitaxel in cationic liposomes resulted in a mechanistic switch from tumor cell toxicity to an antivascular therapy...
Static magnetic fields impair angiogenesis and growth of solid tumors in vivoDonata Strelczyk
Walter Brendel Center for Experimental Medicine WBex, Campus Grosshadern, University of Munich LMU, Munich, Germany
Cancer Biol Ther 8:1756-62. 2009..Hence, SMF therapy appears as a promising new anticancer strategy-as an inhibitor of tumor growth and angiogenesis and as a potential sensitizer to chemotherapy...
Vascular targeting by EndoTAG-1 enhances therapeutic efficacy of conventional chemotherapy in lung and pancreatic cancerMartin E Eichhorn
Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, Germany
Int J Cancer 126:1235-45. 2010..Therefore, this combination represents a promising novel strategy for clinical cancer therapy...
Neovascular targeting therapy: paclitaxel encapsulated in cationic liposomes improves antitumoral efficacyMarcus Schmitt-Sody
Institute for Surgical Research, Department of Otorhinolaryngology, Klinikum Grosshadern, University of Munich, 81377 Munich, Germany
Clin Cancer Res 9:2335-41. 2003..This may serve as proof of the concept of neovascular tumor targeting therapy by cationic liposomes...
Modeling the measurements of cochlear microcirculation and hearing function after loud noiseWarangkana Arpornchayanon
Walter Brendel Center for Experimental Medicine, University of Munich, Munich, Germany
Otolaryngol Head Neck Surg 145:463-9. 2011..The aim of this study was to establish an animal model for in vivo analysis of cochlear microcirculation and hearing function after a loud noise to allow precise measurements of both parameters in vivo...
Automated assessment of tumour microvascular architecture in vivoSven Becker
Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University, Marchioninistrasse 15, D 81377 Munich, Germany
Anticancer Res 30:2597-602. 2010..The aim of this study was to develop an automated analysis technique enabling quantitative assessment of complete tumour vascular networks non-invasively in vivo...
Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activityManuela Schneider
Walter Brendel Center of Experimental Medicine, Ludwig Maximilians University, Marchioninistrasse 15, Munich, Germany
Neoplasia 12:254-63. 2010..Thus, we conclude that GPx4, through controlling 12/15-LOX activity, is an important regulator of tumor angiogenesis as well as vessel maturation...
Quantitative estimation of minor conductive hearing loss with distortion product otoacoustic emissions in the guinea pigBernhard Olzowy
Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University of Munich Medical Center, Marchioninistr 15, 81377 Munich, Germany
J Acoust Soc Am 128:1845-52. 2010..CHL(DPOAE) correlated well with CHL(CAP) (R=0.741, p=0.0142). Mean difference between CHL(DPOAE) and CHL(CAP) was 4.2±2.6 dB. Estimation of minor CHL from DPOAE measurements might help to increase the diagnostic value of DPOAEs...
Anti-vascular tumor therapy: recent advances, pitfalls and clinical perspectivesMartin E Eichhorn
Department of Surgery, Klinikum Grosshadern, University of Munich, Germany
Drug Resist Updat 7:125-38. 2004..Conceptual differences between anti-angiogenic and vascular targeting therapies will be discussed with emphasis on specific problems and pitfalls in the conversion into the clinic...
Acute hyperfibrinogenemia impairs cochlear blood flow and hearing function in guinea pigs in vivoFritz Ihler
Department of Otorhinolaryngology, Head and Neck Surgery, University of Göttingen Hospital, Robert Koch Strasse 40, Gottingen, Germany
Int J Audiol 51:210-5. 2012..Fibrinogen is known as a risk factor for both microvascular dysfunction and SSNHL. Therefore, the aim of this study was to investigate the effect of elevated serum levels of fibrinogen on cochlear blood flow and hearing function in vivo...
Vascular targeting tumor therapy: non-invasive contrast enhanced ultrasound for quantitative assessment of tumor microcirculationMartin E Eichhorn
Department of Surgery, Campus Grosshadern, Walter Brendel Centre of Experimental Medicine WBex, University of Munich, Munich, Germany
Cancer Biol Ther 9:794-802. 2010..Bimodal tumor imaging by intravital microscopy and CEUS represents an experimental tool to further develop molecular imaging of tumor microcirculation by CEUS...
Tumor necrosis factor-α enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine-1-phosphate signalingElias Q Scherer
Hals Nasen Ohrenklinik und Poliklinik, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
Stroke 41:2618-24. 2010..We sought to demonstrate that tumor necrosis factor (TNF)-α, via sphingosine-1-phosphate signaling, has the potential to alter cochlear blood flow and thus, cause ischemic hearing loss...
Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivoFritz Ihler
Department of Otorhinolaryngology, Head and Neck Surgery, Goettingen University Medical School, Gottingen, Germany
PLoS ONE 7:e39086. 2012..This study investigated the effect of betahistine on guinea pigs at dosages corresponding to clinically used doses for cochlear microcirculation...
An animal model for the analysis of cochlear blood flow [corrected] disturbance and hearing threshold in vivoMartin Canis
Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich LMU, Campus Grosshadern, Munich, Germany
Eur Arch Otorhinolaryngol 267:197-203. 2010..This technique can be used to evaluate effects of treatments aimed at cochlear microcirculation in inner ear pathologies...
[Antivascular strategies--a new concept for diagnosis and therapy of head and neck cancer. A review]M Dellian
Klinik und Poliklinik Fur Hals, Nasen und Ohrenkranke der Ludwig Maximilians Universität München, Klinikum Grosshadern
Laryngorhinootologie 81:509-15. 2002..While antiangiogenic therapy prevents neovascularisation by inhibiting new blood vessel growth, the aim of vascular targeting is the destruction of already existing tumor vasculature...
Cationic lipid complexed camptothecin (EndoTAG-2) improves antitumoral efficacy by tumor vascular targetingM E Eichhorn
Department of Surgery and Institute for Surgical Research, Klinikum Grosshadern, University of Munich, Munich, Germany
Cancer Biol Ther 6:920-9. 2007..In conclusion this study shows that cationic lipid complexed camptothecin (EndoTag-2) is a markedly active antitumor agent based on an innovative vascular targeting approach...
Intratympanic treatment of acute acoustic trauma with a cell-permeable JNK ligand: a prospective randomized phase I/II studyM Suckfuell
Ludwig Maximilians Universitat Munchen, Munchen, Germany
Acta Otolaryngol 127:938-42. 2007..Intratympanic administration of a cell-permeable JNK ligand has been shown to prevent hearing loss after acute acoustic trauma in animal models...
Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatmentM E Eichhorn
Department of Surgery, Klinikum Grosshadern, University of Munich LMU, Germany
Cancer Biol Ther 7:1006-13. 2008....
Porous polyethylene implants in revision rhinoplasty: chances and risksKlaus Stelter
Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Centre, Ludwig Maximilians University, Munich, Germany
Rhinology 45:325-31. 2007..The material is being used more frequently in nasal surgery. In this study we describe possibilities and limitations in the use of PE in rhino-surgery...
Level alterations of the 2f (1)-f (2) distortion product due to hypoxia in the guinea pig depend on the stimulus frequencyBernhard Olzowy
Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University of Munich Medical Center, Marchioninistr 15, 81377 Munchen, Germany
Eur Arch Otorhinolaryngol 267:351-5. 2010..16 kHz). DPOAE level alterations due to hypoxia depend on the frequency in guinea pigs. Studies in human are warranted to improve non-invasive ICP monitoring with DPOAE by the detection of hypoxia-related changes...
Paclitaxel encapsulated in cationic lipid complexes (MBT-0206) impairs functional tumor vascular properties as detected by dynamic contrast enhanced magnetic resonance imagingM E Eichhorn
Department of Surgery, Institute for Surgical Research, Klinikum Grosshadern, University of Munich, Munich, Germany
Cancer Biol Ther 5:89-96. 2006..In conclusion, antivascular tumor therapy with MBT-0206 significantly impairs functional tumor microcirculation. DCE-MRI is a promising tool to quantify the antivascular effects of MBT-0206 during treatment...
Contrast-enhanced ultrasound for monitoring effects of extracorporeal shock wave sialolithotripsy in sialolithiasisVanessa Siedek
Department of Otorhinolaryngology, University of Munich, Munich, Germany
Laryngoscope 122:1301-5. 2012..The aim of this investigator-initiated clinical trial was the evaluation of CE-US as a quantitative monitoring technique during gland-preserving extracorporeal shock wave sialolithotripsy (ESWL)...
Protamine enhances uptake of cationic liposomes in angiogenic microvesselsM E Eichhorn
Department of Surgery, Klinikum Grosshadern, University of Munich, Germany
Angiogenesis 7:133-41. 2004..CONCLUSION: Pre-administration of protamine increases the accumulation of cationic liposomes in a solid tumour animal model causing an increased selectivity of cationic liposomes in targeting angiogenic microvessels...
Static magnetic fields affect capillary flow of red blood cells in striated skin muscleGunnar Brix
Federal Office for Radiation Protection, Department of Medical Radiation Hygiene and Dosimetry, Neuherberg, Germany
Microcirculation 15:15-26. 2008....
