Matthias B Stope

Summary

Affiliation: University of Greifswald
Country: Germany

Publications

  1. doi request reprint Jump in the fire - heat shock proteins and their impact on ovarian cancer therapy
    M B Stope
    Department of Urology, University Medicine Greifswald, Greifswald, Germany Electronic address
    Crit Rev Oncol Hematol 97:152-6. 2016
  2. doi request reprint Androgen receptor (AR) inhibitor ErbB3-binding protein-1 (Ebp1) is not targeted by the newly identified AR controlling signaling axis heat-shock protein HSP27 and microRNA miR-1 in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Ferdinand Sauerbruch Straße, 17475, Greifswald, Germany
    World J Urol 33:323-7. 2015
  3. ncbi request reprint Heat-shock protein HSPB1 attenuates microRNA miR-1 expression thereby restoring oncogenic pathways in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    Anticancer Res 34:3475-80. 2014
  4. ncbi request reprint Shortened isoforms of the androgen receptor are regulated by the cytoprotective heat-shock protein HSPB1 and the tumor-suppressive microRNA miR-1 in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Ferdinand Sauerbruch Str, D 17475 Greifswald, Germany
    Anticancer Res 33:4921-6. 2013
  5. doi request reprint Effect of the heat shock protein HSP27 on androgen receptor expression and function in prostate cancer cells
    Matthias B Stope
    Department of Urology, Ernst Moritz Arndt University of Greifswald, Ferdinand Sauerbruch Straße, 17475, Greifswald, Germany
    World J Urol 30:327-31. 2012
  6. doi request reprint [Transforming growth factor β in prostate cancer: cellular effects and basic molecular mechanisms]
    M B Stope
    Klinik und Poliklinik fur Urologie, Universitätsmedizin Greifswald, Ernst Moritz Arndt Universitat Greifswald, Ferdinand Sauerbruch Straße, 17475 Greifswald, Deutschland
    Urologe A 52:378-83. 2013
  7. ncbi request reprint Antiestrogens suppress effects of transforming growth factor-β in breast cancer cells via the signaling axis estrogen receptor-α and Y-box Binding Protein-1
    Simone L Popp
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    Anticancer Res 33:2473-80. 2013
  8. ncbi request reprint Inhibition of Cell Growth of the Prostate Cancer Cell Model LNCaP by Cold Atmospheric Plasma
    Martin Weiss
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    In Vivo 29:611-6. 2015
  9. doi request reprint Immediate and transient phosphorylation of the heat shock protein 27 initiates chemoresistance in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    Oncol Rep 32:2380-6. 2014
  10. doi request reprint Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment
    Lisa Rauschenberger
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    Prostate 76:409-24. 2016

Collaborators

  • Stefan Oswald
  • Martin Burchardt
  • Uwe Zimmermann
  • Martin Weiss
  • Reinhard Walther
  • Lisa Rauschenberger
  • Robert Mandelkow
  • Cornelius Knabbe
  • Hannah Grossebrummel
  • Patrick Ziegler
  • Lars Ove Brandenburg
  • Denis Gümbel
  • Nadine Gelbrich
  • Madeleine Saupe
  • Simone L Popp
  • Uwe Lendeckel
  • Damián Muzzio
  • Simone Venz
  • Marek Zygmunt
  • Tilmann Peter
  • Kathleen Thom
  • Federico Jensen
  • Christian Scharf
  • Werner Weitschies
  • Uwe Volker
  • Doreen Staar
  • Rabea Schlüter
  • Georg Homuth
  • Axel Ekkernkamp
  • Melanie Preuß
  • Christopher H Lillig
  • Axel Kramer
  • Sebastian Fussek
  • Axel Sckell
  • Eva Maria Hanschmann
  • Peter Fritz
  • Miriam B Buck
  • Christian Joffroy

Detail Information

Publications13

  1. doi request reprint Jump in the fire - heat shock proteins and their impact on ovarian cancer therapy
    M B Stope
    Department of Urology, University Medicine Greifswald, Greifswald, Germany Electronic address
    Crit Rev Oncol Hematol 97:152-6. 2016
    ..Despite the limited knowledge on HSPs in OC progression, their roles as biomarkers, prognostic factors and their drug target properties appears promising for future clinical applications and therapeutic approaches. ..
  2. doi request reprint Androgen receptor (AR) inhibitor ErbB3-binding protein-1 (Ebp1) is not targeted by the newly identified AR controlling signaling axis heat-shock protein HSP27 and microRNA miR-1 in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Ferdinand Sauerbruch Straße, 17475, Greifswald, Germany
    World J Urol 33:323-7. 2015
    ..In this study, an assumed regulation of Ebp1 by the newly identified AR controlling signaling axis heat-shock protein 27 (HSP27)-microRNA-1 (miR-1) was examined...
  3. ncbi request reprint Heat-shock protein HSPB1 attenuates microRNA miR-1 expression thereby restoring oncogenic pathways in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    Anticancer Res 34:3475-80. 2014
    ..Due to cytoprotective properties of HSPB1 we analyzed molecular mechanisms of drug resistance in PCa cell culture systems, and notably found HSPB1 functionality linked to microRNA miR-1 activities...
  4. ncbi request reprint Shortened isoforms of the androgen receptor are regulated by the cytoprotective heat-shock protein HSPB1 and the tumor-suppressive microRNA miR-1 in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Ferdinand Sauerbruch Str, D 17475 Greifswald, Germany
    Anticancer Res 33:4921-6. 2013
    ..We examined the regulation of shortened AR isoforms by a newly-identified AR regulatory signaling pathway involving heat-shock protein HSPB1 and microRNA miR-1...
  5. doi request reprint Effect of the heat shock protein HSP27 on androgen receptor expression and function in prostate cancer cells
    Matthias B Stope
    Department of Urology, Ernst Moritz Arndt University of Greifswald, Ferdinand Sauerbruch Straße, 17475, Greifswald, Germany
    World J Urol 30:327-31. 2012
    ..In order to study the functional relationship between HSP27 and the AR, we modulated the expression of the small heat shock protein HSP27 in human prostate cancer (PC) cell lines...
  6. doi request reprint [Transforming growth factor β in prostate cancer: cellular effects and basic molecular mechanisms]
    M B Stope
    Klinik und Poliklinik fur Urologie, Universitätsmedizin Greifswald, Ernst Moritz Arndt Universitat Greifswald, Ferdinand Sauerbruch Straße, 17475 Greifswald, Deutschland
    Urologe A 52:378-83. 2013
    ..Although TGFβ plays an important role in tumor progression little is known about the underlying effects of TGFβ in the molecular pathology of PCa...
  7. ncbi request reprint Antiestrogens suppress effects of transforming growth factor-β in breast cancer cells via the signaling axis estrogen receptor-α and Y-box Binding Protein-1
    Simone L Popp
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    Anticancer Res 33:2473-80. 2013
    ..Thus, a putative influence of YB1 on TGFβ signaling should be investigated...
  8. ncbi request reprint Inhibition of Cell Growth of the Prostate Cancer Cell Model LNCaP by Cold Atmospheric Plasma
    Martin Weiss
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    In Vivo 29:611-6. 2015
    ..Backround/Aim: Physical plasmas are ionized gases containing several biologically-reactive factors that yet exert their anti-microbial and anti-proliferative effects in fields of surface sterilisation, de-contamination and wound healing...
  9. doi request reprint Immediate and transient phosphorylation of the heat shock protein 27 initiates chemoresistance in prostate cancer cells
    Matthias B Stope
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    Oncol Rep 32:2380-6. 2014
    ..The protective function depends on the initial phosphorylation status of HSP27 and represents a putative co-therapeutic target to prevent chemoresistance during docetaxel therapy. ..
  10. doi request reprint Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment
    Lisa Rauschenberger
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    Prostate 76:409-24. 2016
    ..We characterized the mRNA and protein composition as well as cellular functions of prostate cancer cell-derived exosomes...
  11. doi request reprint Cytochrome P450 17A1 inhibitor abiraterone attenuates cellular growth of prostate cancer cells independently from androgen receptor signaling by modulation of oncogenic and apoptotic pathways
    Hannah Grossebrummel
    Department of Urology, University Medicine Greifswald, D 17475 Greifswald, Germany
    Int J Oncol 48:793-800. 2016
    ..In this regard, abiraterone is not only a promising drug for treatment of AR-negative PC stages, even more, abiraterone may represent an alternative for treatment of other malignancies besides prostate cancer. ..
  12. doi request reprint Differential expression of the multidrug resistance 1 (MDR1) protein in prostate cancer cells is independent from anticancer drug treatment and Y box binding protein 1 (YB-1) activity
    Madeleine Saupe
    Department of Urology, University Medicine Greifswald, Ferdinand Sauerbruch Straße, 17475, Greifswald, Germany
    World J Urol 33:1481-6. 2015
    ..Believed to be involved in the induction of MDR1 expression is the presence of anticancer drugs as well as the Y box binding protein 1 (YB-1)...
  13. doi request reprint Cold Atmospheric Plasma Treatment Induces Anti-Proliferative Effects in Prostate Cancer Cells by Redox and Apoptotic Signaling Pathways
    Martin Weiss
    Department of Urology, University Medicine Greifswald, Greifswald, Germany
    PLoS ONE 10:e0130350. 2015
    ..We assume that the general intracellular redox homeostasis, especially the levels of cellular GSH and peroxidases such as peroxiredoxins affect the outcome of the CAP treatment...